Christiane Dolecek

Summary

Affiliation: Ho Chi Minh City
Country: Vietnam

Publications

  1. pmc A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children
    Tinh Hien Tran
    The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS ONE 5:e11778. 2010
  2. pmc In vivo susceptibility of Plasmodium falciparum to artesunate in Binh Phuoc Province, Vietnam
    Tran Tinh Hien
    Wellcome Trust Major Overseas Programme MOP, Oxford University Clinical Research Unit OUCRU, Ho Chi Minh City, Vietnam
    Malar J 11:355. 2012
  3. pmc A multi-center randomised controlled trial of gatifloxacin versus azithromycin for the treatment of uncomplicated typhoid fever in children and adults in Vietnam
    Christiane Dolecek
    Oxford University Clinical Research Unit, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS ONE 3:e2188. 2008
  4. pmc Combined high-resolution genotyping and geospatial analysis reveals modes of endemic urban typhoid fever transmission
    Stephen Baker
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Open Biol 1:110008. 2011
  5. doi request reprint The decline of typhoid and the rise of non-typhoid salmonellae and fungal infections in a changing HIV landscape: bloodstream infection trends over 15 years in southern Vietnam
    Tran Vu Thieu Nga
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Trans R Soc Trop Med Hyg 106:26-34. 2012
  6. pmc The sensitivity of real-time PCR amplification targeting invasive Salmonella serovars in biological specimens
    Tran Vu Thieu Nga
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    BMC Infect Dis 10:125. 2010
  7. pmc Suitable disk antimicrobial susceptibility breakpoints defining Salmonella enterica serovar Typhi isolates with reduced susceptibility to fluoroquinolones
    Christopher M Parry
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Antimicrob Agents Chemother 54:5201-8. 2010
  8. pmc A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children
    Ha Vinh
    The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS Negl Trop Dis 5:e1264. 2011
  9. pmc A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure
    Duy Pham Thanh
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    elife 5:e14003. 2016
  10. pmc Undifferentiated febrile illness in Kathmandu, Nepal
    Corinne N Thompson
    Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam The London School of Hygiene and Tropical Medicine, London, United Kingdom Wellcome Trust, London, United Kingdom Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Oxford University Clinical Research Unit Nepal, Patan Academy of Health Sciences, Lalitpur, Nepal
    Am J Trop Med Hyg 92:875-8. 2015

Collaborators

Detail Information

Publications12

  1. pmc A randomised trial evaluating the safety and immunogenicity of the novel single oral dose typhoid vaccine M01ZH09 in healthy Vietnamese children
    Tinh Hien Tran
    The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS ONE 5:e11778. 2010
    ..Studies in healthy adults demonstrated immunogenicity and an acceptable safety profile...
  2. pmc In vivo susceptibility of Plasmodium falciparum to artesunate in Binh Phuoc Province, Vietnam
    Tran Tinh Hien
    Wellcome Trust Major Overseas Programme MOP, Oxford University Clinical Research Unit OUCRU, Ho Chi Minh City, Vietnam
    Malar J 11:355. 2012
    ..Therefore, there is an urgent need to investigate whether there is any evidence of a change in the parasitological response to the artemisinin derivatives in Vietnam...
  3. pmc A multi-center randomised controlled trial of gatifloxacin versus azithromycin for the treatment of uncomplicated typhoid fever in children and adults in Vietnam
    Christiane Dolecek
    Oxford University Clinical Research Unit, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS ONE 3:e2188. 2008
    ..Drug resistant typhoid fever is a major clinical problem globally. Many of the first line antibiotics, including the older generation fluoroquinolones, ciprofloxacin and ofloxacin, are failing...
  4. pmc Combined high-resolution genotyping and geospatial analysis reveals modes of endemic urban typhoid fever transmission
    Stephen Baker
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Open Biol 1:110008. 2011
    ..These findings have implications for typhoid-control strategies, and our innovative approach may be applied to other diseases caused by other monophyletic or emerging pathogens...
  5. doi request reprint The decline of typhoid and the rise of non-typhoid salmonellae and fungal infections in a changing HIV landscape: bloodstream infection trends over 15 years in southern Vietnam
    Tran Vu Thieu Nga
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Trans R Soc Trop Med Hyg 106:26-34. 2012
    ..We propose such changes are related to increasing economic prosperity and HIV prevalence, and this pattern marks a substantial change in the epidemiology of invasive salmonellosis in Southeast Asia...
  6. pmc The sensitivity of real-time PCR amplification targeting invasive Salmonella serovars in biological specimens
    Tran Vu Thieu Nga
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    BMC Infect Dis 10:125. 2010
    ..Invasive Salmonella serovars, which cause enteric fever, can be commonly cultured from the blood of infected patients. Yet, the isolation of invasive Salmonella serovars from blood is protracted and potentially insensitive...
  7. pmc Suitable disk antimicrobial susceptibility breakpoints defining Salmonella enterica serovar Typhi isolates with reduced susceptibility to fluoroquinolones
    Christopher M Parry
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Antimicrob Agents Chemother 54:5201-8. 2010
    ..Screening for nalidixic acid resistance or ciprofloxacin and ofloxacin disk inhibition zone are suitable for detecting S. Typhi isolates with reduced fluoroquinolone susceptibility...
  8. pmc A multi-center randomized trial to assess the efficacy of gatifloxacin versus ciprofloxacin for the treatment of shigellosis in Vietnamese children
    Ha Vinh
    The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS Negl Trop Dis 5:e1264. 2011
    ..We aimed to assess the efficacy of gatifloxacin versus ciprofloxacin in the treatment of uncomplicated shigellosis in children...
  9. pmc A novel ciprofloxacin-resistant subclade of H58 Salmonella Typhi is associated with fluoroquinolone treatment failure
    Duy Pham Thanh
    The Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    elife 5:e14003. 2016
    ..01)(pS. Typhi clade internationally, but there are no data regarding disease outcome with this organism. We report an emergent new subclade of S. Typhi-H58 that is associated with fluoroquinolone treatment failure. ..
  10. pmc Undifferentiated febrile illness in Kathmandu, Nepal
    Corinne N Thompson
    Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam The London School of Hygiene and Tropical Medicine, London, United Kingdom Wellcome Trust, London, United Kingdom Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Oxford University Clinical Research Unit Nepal, Patan Academy of Health Sciences, Lalitpur, Nepal
    Am J Trop Med Hyg 92:875-8. 2015
    ..Murine typhus represents an important cause of predominantly urban UFIs in Nepal, and fluoroquinolones seem to be an effective empirical treatment. ..
  11. pmc Clinically and microbiologically derived azithromycin susceptibility breakpoints for Salmonella enterica serovars Typhi and Paratyphi A
    Christopher M Parry
    Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam Centre for Tropical Medicine and Global Health, Old Road Campus, University of Oxford, Oxford, United Kingdom Liverpool School of Tropical Medicine, Liverpool, United Kingdom London School of Hygiene and Tropical Medicine, London, United Kingdom School of Tropical Medicine and Global Health, Nagasaki University, Nagasaki, Japan
    Antimicrob Agents Chemother 59:2756-64. 2015
    ..Further work is needed to define the response to treatment in S. Typhi isolates with an azithromycin MIC of >16 μg/ml and to determine MIC and disk breakpoints for S. Paratyphi A...
  12. pmc Antimicrobial drug resistance of Salmonella enterica serovar typhi in asia and molecular mechanism of reduced susceptibility to the fluoroquinolones
    Tran Thuy Chau
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, Ho Chi Minh City, Vietnam
    Antimicrob Agents Chemother 51:4315-23. 2007
    ..The 8-methoxy fluoroquinolone gatifloxacin showed rapid killing of serovar Typhi harboring both the single- and double-amino-acid substitutions...