Ho Chi Minh City

Summary

Organization: Ho Chi Minh City
Country: Vietnam

Top Publications

  1. ncbi Neurological infections: clinical advances and emerging threats
    Me Török
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, District 5, Ho Chi Minh City, Vietnam
    Lancet Neurol 6:16-8. 2007
  2. doi Hemostatic changes in Vietnamese children with mild dengue correlate with the severity of vascular leakage rather than bleeding
    Bridget Wills
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
    Am J Trop Med Hyg 81:638-44. 2009
  3. pmc A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentation
    Ha Vinh
    The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    BMC Infect Dis 9:204. 2009
  4. pmc Microscopic observation drug susceptibility assay (MODS) for early diagnosis of tuberculosis in children
    Dang Thi Minh Ha
    TB Department, Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam
    PLoS ONE 4:e8341. 2009
  5. pmc A real-time RT-PCR for detection of clade 1 and 2 H5N1 influenza A virus using locked nucleic acid (LNA) TaqMan probes
    Tran Tan Thanh
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, Dist 05, Ho Chi Minh City, Viet Nam
    Virol J 7:46. 2010
  6. pmc Pretreatment CD4 cell slope and progression to AIDS or death in HIV-infected patients initiating antiretroviral therapy--the CASCADE collaboration: a collaboration of 23 cohort studies
    Marcel Wolbers
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    PLoS Med 7:e1000239. 2010
  7. pmc Searching for the elusive typhoid diagnostic
    Stephen Baker
    Oxford University Clinical Research Unit, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    BMC Infect Dis 10:45. 2010
  8. pmc Randomized controlled trial of artesunate or artemether in Vietnamese adults with severe falciparum malaria
    Nguyen H Phu
    Hospital for Tropical Diseases, 190 Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Malar J 9:97. 2010
  9. pmc Guidelines for identifying homologous recombination events in influenza A virus
    Maciej F Boni
    Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    PLoS ONE 5:e10434. 2010
  10. pmc Influenza A H5N1 and HIV co-infection: case report
    Annette Fox
    Oxford University Clinical Research Unit Viet Nam, Wellcome Trust Major Overseas Program, National Hospital of Tropical Diseases, 78 Giai Phong Road, Dong da, Ha Noi, Viet Nam
    BMC Infect Dis 10:167. 2010

Scientific Experts

  • Walter Rj Taylor
  • Maciej F Boni
  • Marcel Wolbers
  • Jeremy Farrar
  • Me Török
  • Dang Thi Minh Ha
  • Dinh The Trung
  • Thuy Le
  • Stephen Baker
  • Annette Fox
  • Tran T Hien
  • Ha Vinh
  • Thanh Tran Tan
  • Bridget Wills
  • Heiman F L Wertheim
  • H Rogier van Doorn
  • Christiane Dolecek
  • Jean Paul Charlieu
  • Dang Thi Minh Ha
  • Van Tan Le
  • Menno D de Jong
  • Khoa T D Thai
  • Nguyen H Phu
  • Tran Tan Thanh
  • Nguyen Huy Dung
  • Tran Van Quyet
  • Vo Sy Kiet
  • Jeremy Day
  • Nguyen Thi Nho
  • Dai Viet Hoa
  • Hoang Thi Thanh Hang
  • Nguyen Thi Bich Tuyen
  • Maxine Caws
  • Nguyen Thi Ngoc Lan
  • Vo Thi Ha
  • Tinh Hien Tran
  • Sarah J Dunstan
  • Truong Thi Anh
  • Nghiem My Ngoc
  • Doan Thanh Phuong
  • Ngo Thanh Binh
  • Tu Qui Phan
  • Pham Thuy An
  • Nicholas Day
  • Quang Ha do
  • Chau Luong Hoa
  • Bach Hue Nguyen
  • Van Cam Bach
  • Nguyen Quang Hien
  • Nguyen Thi Minh Chau
  • Peter J de Vries
  • Van Vinh Chau Nguyen
  • Endang R Sedyaningsih
  • Dinh X Sinh
  • Quoi Bao Lam
  • Harun Syahrial
  • Ly V Chuong
  • Huu Khanh Truong
  • Phung Q Tuan
  • Le Hong Ngoc
  • Phan Thi Hoang Anh
  • Tran T H Chau
  • Long Thi Vo
  • Vu Thieu Nga Tran
  • Nguyen Anh Tien
  • Cameron P Simmons
  • Nguyen T H Mai
  • Bernard Cazelles
  • Vo Minh Hien
  • Minh Hien Vo
  • Nam Van Nguyen
  • Hana Apsari Pawestri
  • Tan Tram Tran
  • Nicholas J White
  • Nguyen Ngoc Hai
  • Nguyen Van Vinh Chau
  • Nguyen Vu Trung
  • Quang Ha Do
  • Do Thi Tuong Oanh
  • Constance Schultsz
  • Rogier H van Doorn
  • Tran Ngoc Duong
  • Nguyen Huu Lan
  • Le Thi Hong Ngoc
  • Nguyen Dang Quang
  • Tran Thi Van Thinh
  • Nguyen Thi Ngoc Anh
  • Vinh Ha
  • Mahamadou Diakite
  • Ngoc Lanh Mai

Detail Information

Publications32

  1. ncbi Neurological infections: clinical advances and emerging threats
    Me Török
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, District 5, Ho Chi Minh City, Vietnam
    Lancet Neurol 6:16-8. 2007
  2. doi Hemostatic changes in Vietnamese children with mild dengue correlate with the severity of vascular leakage rather than bleeding
    Bridget Wills
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Viet Nam
    Am J Trop Med Hyg 81:638-44. 2009
    ..The findings do not support a primary diagnosis of disseminated intravascular coagulation to explain the intrinsic coagulopathy. An alternative biologically plausible hypothesis is discussed...
  3. pmc A changing picture of shigellosis in southern Vietnam: shifting species dominance, antimicrobial susceptibility and clinical presentation
    Ha Vinh
    The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    BMC Infect Dis 9:204. 2009
    ..Antimicrobial resistance in the genus Shigella is a constant threat, with reports of organisms in Asia being resistant to multiple antimicrobials and new generation therapies...
  4. pmc Microscopic observation drug susceptibility assay (MODS) for early diagnosis of tuberculosis in children
    Dang Thi Minh Ha
    TB Department, Pham Ngoc Thach Hospital, Ho Chi Minh City, Vietnam
    PLoS ONE 4:e8341. 2009
    ..001 and P = 0.04), respectively. MODS is a rapid and sensitive alternative method for the isolation of M.tuberculosis from children...
  5. pmc A real-time RT-PCR for detection of clade 1 and 2 H5N1 influenza A virus using locked nucleic acid (LNA) TaqMan probes
    Tran Tan Thanh
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, Dist 05, Ho Chi Minh City, Viet Nam
    Virol J 7:46. 2010
    ..The emergence and co-circulation of two different clades (clade 1 and 2) of H5N1 influenza viruses in Vietnam necessitates the availability of a diagnostic assay that can detect both variants...
  6. pmc Pretreatment CD4 cell slope and progression to AIDS or death in HIV-infected patients initiating antiretroviral therapy--the CASCADE collaboration: a collaboration of 23 cohort studies
    Marcel Wolbers
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    PLoS Med 7:e1000239. 2010
    ..It is not known whether the rate of CD4 cell decline prior to therapy is related to prognosis and should, therefore, influence the decision on when to initiate cART...
  7. pmc Searching for the elusive typhoid diagnostic
    Stephen Baker
    Oxford University Clinical Research Unit, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    BMC Infect Dis 10:45. 2010
    ..Here we discuss the current position of typhoid diagnostics, highlight the need for technological improvements and suggest potential ways of advancing this area...
  8. pmc Randomized controlled trial of artesunate or artemether in Vietnamese adults with severe falciparum malaria
    Nguyen H Phu
    Hospital for Tropical Diseases, 190 Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    Malar J 9:97. 2010
    ..These two artemisinin derivatives had not been compared in a randomized trial...
  9. pmc Guidelines for identifying homologous recombination events in influenza A virus
    Maciej F Boni
    Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    PLoS ONE 5:e10434. 2010
    ....
  10. pmc Influenza A H5N1 and HIV co-infection: case report
    Annette Fox
    Oxford University Clinical Research Unit Viet Nam, Wellcome Trust Major Overseas Program, National Hospital of Tropical Diseases, 78 Giai Phong Road, Dong da, Ha Noi, Viet Nam
    BMC Infect Dis 10:167. 2010
    ..The role of adaptive immunity in severe influenza is poorly understood. The occurrence of influenza A/H5N1 in a patient with HIV provided a rare opportunity to investigate this...
  11. pmc Dengue dynamics in Binh Thuan province, southern Vietnam: periodicity, synchronicity and climate variability
    Khoa T D Thai
    Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, Amsterdam, The Netherlands
    PLoS Negl Trop Dis 4:e747. 2010
    ..The epidemiology is complex with long inter-epidemic intervals and endemic with seasonal fluctuations. This study was initiated to investigate dengue transmission dynamics in Binh Thuan province, southern Vietnam...
  12. pmc Navigating the future of bacterial molecular epidemiology
    Stephen Baker
    Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, Hospital for Tropical Diseases, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Viet Nam
    Curr Opin Microbiol 13:640-5. 2010
    ..As genome sequencing, SNP detection and geospatial information become more accessible these methods will continue to transform the way molecular epidemiology is used to study populations of bacterial pathogens...
  13. doi AIDS‐associated Cryptococcus neoformans and Penicillium marneffei coinfection: a therapeutic dilemma in resource‐limited settings
    Thuy Le
    Wellcome Trust Major Overseas Programmes, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    Clin Infect Dis 51:e65-8. 2010
    ..Itraconazole poorly penetrates the central nervous system, whereas fluconazole has poor activity against P. marneffei. We prospectively report management of 1 patient and retrospectively review 7 coinfection cases from Vietnam...
  14. pmc Liver involvement associated with dengue infection in adults in Vietnam
    Dinh The Trung
    Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    Am J Trop Med Hyg 83:774-80. 2010
    ..Chronic co-infection with hepatitis B was associated with modestly but significantly increased levels of alanine aminotransferase, but did not otherwise impact the clinical picture...
  15. pmc Diagnosis of pulmonary tuberculosis in HIV-positive patients by microscopic observation drug susceptibility assay
    Dang Thi Minh Ha
    Pham Ngoc Thach Hospital, and Wellcome Trust Mamor Overseas Programme, Oxford University Clinical Research Unit, 120 Hung Vuong, District 5, Ho Chi Minh City, Vietnam
    J Clin Microbiol 48:4573-9. 2010
    ..7%. In conclusion, MODS is a sensitive, specific, and rapid test that is appropriate for the detection of HIV-associated TB; its cost and ease of use make it particularly useful in resource-limited settings...
  16. pmc Modelling the progression of pandemic influenza A (H1N1) in Vietnam and the opportunities for reassortment with other influenza viruses
    Maciej F Boni
    Oxford University Clinical Research Unit, Vietnam
    BMC Med 7:43. 2009
    ..This is of greater concern in parts of Southeast Asia, where the population density is high, influenza is less seasonal, human-animal contact is common and avian influenza is still endemic...
  17. doi Acute febrile myalgia in Vietnam due to trichinellosis following the consumption of raw pork
    Walter R J Taylor
    Oxford University Clinical Research Unit, London, United Kingdom
    Clin Infect Dis 49:e79-83. 2009
    ..Diagnosing trichinella can be problematic because fever and myalgia are nonspecific, and diagnosis may be delayed. We describe 5 Vietnamese patients in whom trichinellosis was diagnosed after several weeks of illness...
  18. pmc A TNF region haplotype offers protection from typhoid fever in Vietnamese patients
    Sarah J Dunstan
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, Quan 5, District 5, Ho Chi Minh City, Vietnam
    Hum Genet 122:51-61. 2007
    ..Finally, individuals that carry the typhoid fever protective haplotype *12122*1111 also produce a relatively low TNF-alpha response to LPS...
  19. ncbi A personal perspective on clinical research in Enteric Fever
    Jeremy Farrar
    The Hospital for Tropical Diseases, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam
    Clin Infect Dis 45:S9-14. 2007
    ..Better integration of clinical medicine with epidemiology, public health, vaccine development, and modern laboratory science will help to yield tangible benefits for the vast number of people who have this disease...
  20. ncbi Global health science: a threat and an opportunity for collaborative clinical science
    Jeremy Farrar
    The Hospital for Tropical Diseases, Ho Chi Minh City, Quan 5, Viet Nam
    Nat Immunol 8:1277-9. 2007
  21. pmc High-throughput genotyping of Salmonella enterica serovar Typhi allowing geographical assignment of haplotypes and pathotypes within an urban District of Jakarta, Indonesia
    Stephen Baker
    The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom
    J Clin Microbiol 46:1741-6. 2008
    ..The study also provides insight into the evolution of serovar Typhi and demonstrates the value of a molecular epidemiological technique that is exchangeable, that is internet friendly, and that has global utility...
  22. pmc Clinical and microbiological features of HIV-associated tuberculous meningitis in Vietnamese adults
    M Estee Torok
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS ONE 3:e1772. 2008
    ..58 patients were admitted to the Hospital for Tropical Diseases in Ho Chi Minh City and underwent routine clinical and laboratory assessments...
  23. pmc Mobilization of the incQ plasmid R300B with a chromosomal conjugation system in Salmonella enterica serovar typhi
    Stephen Baker
    The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire, United Kingdom
    J Bacteriol 190:4084-7. 2008
    ..Evidence suggests that SPI-7 is susceptible to spontaneous circularization, loss, and transposition. Here, we demonstrate that a region within SPI-7 has the ability to mobilize the small incQ plasmid R300B...
  24. pmc A multi-center randomised controlled trial of gatifloxacin versus azithromycin for the treatment of uncomplicated typhoid fever in children and adults in Vietnam
    Christiane Dolecek
    Oxford University Clinical Research Unit, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS ONE 3:e2188. 2008
    ..Drug resistant typhoid fever is a major clinical problem globally. Many of the first line antibiotics, including the older generation fluoroquinolones, ciprofloxacin and ofloxacin, are failing...
  25. ncbi Fluoroquinolone resistance detection in Mycobacterium tuberculosis with locked nucleic acid probe real-time PCR
    H R van Doorn
    Department of Medical Microbiology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Int J Tuberc Lung Dis 12:736-42. 2008
    Pham Ngoc Thach Hospital for Tuberculosis and Lung Diseases, Ho Chi Minh City, Vietnam.
  26. pmc Benefits of using multiple first-line therapies against malaria
    Maciej F Boni
    Resources for the Future, Washington, DC 20036, USA
    Proc Natl Acad Sci U S A 105:14216-21. 2008
    ..The clinical benefits of using multiple first-line therapies against malaria suggest that MFT policies should play a key role in malaria elimination and control programs...
  27. pmc Fatal wound infection caused by Chromobacterium violaceum in Ho Chi Minh City, Vietnam
    Stephen Baker
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, 190 Ben Ham Tu, Quan 5, Ho Chi Minh City, Vietnam
    J Clin Microbiol 46:3853-5. 2008
    ..Here, we report a fatal bacteremia caused by Chromobacterium violaceum in Vietnam. We describe a number of clinical, microbiological, and molecular aspects associated with this bacterial infection...
  28. pmc Oseltamivir is adequately absorbed following nasogastric administration to adult patients with severe H5N1 influenza
    Walter R J Taylor
    Oxford University Clinical Research Unit, Hanoi, Vietnam
    PLoS ONE 3:e3410. 2008
    ..150 mg bid of oseltamivir was well absorbed and converted extensively to OC. Virus was cleared in two patients but two patients died, suggesting viral efficacy but poor clinical efficacy...
  29. pmc Changes in the total leukocyte and platelet counts in Papuan and non Papuan adults from northeast Papua infected with acute Plasmodium vivax or uncomplicated Plasmodium falciparum malaria
    Walter R J Taylor
    The US Navy Medical Research Unit no 2, Jakarta, Indonesia
    Malar J 7:259. 2008
    ..There are limited data on the evolution of the leukocyte and platelet counts in malaria patients...
  30. doi Prognostic models with competing risks: methods and application to coronary risk prediction
    Marcel Wolbers
    Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital Basel, Basel, Switzerland
    Epidemiology 20:555-61. 2009
    ..We conclude that competing risks have to be considered explicitly in frail populations such as the elderly...
  31. pmc Streptococcus suis, an important cause of adult bacterial meningitis in northern Vietnam
    Heiman F L Wertheim
    Oxford University Clinical Research Unit, National Institute of Infectious and Tropical Diseases, Hanoi, Viet Nam
    PLoS ONE 4:e5973. 2009
    ..S. suis is often misdiagnosed, due to lack of awareness and improper testing. Here we report the first fifty cases diagnosed with S. suis infection in northern Viet Nam...
  32. pmc Viral etiology of encephalitis in children in southern Vietnam: results of a one-year prospective descriptive study
    Van Tan Le
    Oxford University Clinical Research Unit, South East Asia Infectious Diseases Clinical Research Network, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    PLoS Negl Trop Dis 4:e854. 2010
    ..To identify viral causes of encephalitis, in 2004 we conducted a one-year descriptive study at Children's Hospital Number One, a referral hospital for children in southern Vietnam including Ho Chi Minh City.