Alexander O Vargas

Summary

Publications

  1. pmc New developmental evidence supports a homeotic frameshift of digit identity in the evolution of the bird wing
    Miguel Salinas-Saavedra
    Laboratorio de Ontogenia y Filogenia, Departamento de Biologia, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425, Nunoa, Santiago, Chile
    Front Zool 11:33. 2014
  2. doi request reprint Did Paul Kammerer discover epigenetic inheritance? A modern look at the controversial midwife toad experiments
    Alexander O Vargas
    Laboratory of Ontogeny and Phylogeny, Department of Biology, Faculty of Science, University of Chile, Las Palmeras, Nunoa, Casilla, Santiago, Chile
    J Exp Zool B Mol Dev Evol 312:667-78. 2009
  3. pmc The evolution of HoxD-11 expression in the bird wing: insights from Alligator mississippiensis
    Alexander O Vargas
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA
    PLoS ONE 3:e3325. 2008
  4. doi request reprint Evolution of digit identity in the three-toed Italian skink Chalcides chalcides: a new case of digit identity frame shift
    Rebecca L Young
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    Evol Dev 11:647-58. 2009
  5. doi request reprint Frame-shifts of digit identity in bird evolution and Cyclopamine-treated wings
    Alexander O Vargas
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8106, USA
    Evol Dev 11:163-9. 2009
  6. doi request reprint Greater Growth of Proximal Metatarsals in Bird Embryos and the Evolution of Hallux Position in the Grasping Foot
    João Francisco Botelho
    Departamento de Biologia, Laboratorio de Ontogenia y Filogenia, Facultad de Ciencias de la Universidad de Chile, Santiago, RM, Chile
    J Exp Zool B Mol Dev Evol . 2016
  7. ncbi request reprint The digits of the wing of birds are 1, 2, and 3. A review
    Alexander O Vargas
    Programa de Anatomía y Biología del Desarrollo, Facultad de Medicina, Universidad de Chile, Independencia 1027, Casilla 70 079 Santiago 7, Santiago, Chile
    J Exp Zool B Mol Dev Evol 304:206-19. 2005
  8. pmc Molecular development of fibular reduction in birds and its evolution from dinosaurs
    João Francisco Botelho
    Laboratorio de Ontogenia y Filogenia, Departamento de Biologia, Facultad de Ciencias de la Universidad de Chile, Santiago, Chile
    Evolution 70:543-54. 2016
  9. pmc New developmental evidence clarifies the evolution of wrist bones in the dinosaur-bird transition
    João Francisco Botelho
    Laboratorio de Ontogenia y Filogenia, Departamento de Biologia, Facultad de Ciencias, Universidad de Chile, Santiago, Chile
    PLoS Biol 12:e1001957. 2014
  10. pmc On the nature of thumbs
    Gunter P Wagner
    Department of Ecology and Evolutionary Biology, Yale University, Prospect Street, New Haven, CT 06520 8106, USA
    Genome Biol 9:213. 2008

Collaborators

Detail Information

Publications15

  1. pmc New developmental evidence supports a homeotic frameshift of digit identity in the evolution of the bird wing
    Miguel Salinas-Saavedra
    Laboratorio de Ontogenia y Filogenia, Departamento de Biologia, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425, Nunoa, Santiago, Chile
    Front Zool 11:33. 2014
    ..We tested these hypotheses using DiI injections to study the fate of cells in these experimental wings...
  2. doi request reprint Did Paul Kammerer discover epigenetic inheritance? A modern look at the controversial midwife toad experiments
    Alexander O Vargas
    Laboratory of Ontogeny and Phylogeny, Department of Biology, Faculty of Science, University of Chile, Las Palmeras, Nunoa, Casilla, Santiago, Chile
    J Exp Zool B Mol Dev Evol 312:667-78. 2009
    ..Given available molecular tools and our current understanding of epigenetics, new experimentation with the midwife toad is strongly encouraged...
  3. pmc The evolution of HoxD-11 expression in the bird wing: insights from Alligator mississippiensis
    Alexander O Vargas
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, Connecticut, USA
    PLoS ONE 3:e3325. 2008
    ..If this is the case, we can expect closer relatives of birds to show no HoxD-11 expression only in digit 1. To test this prediction we investigate HoxD-11 expression in crocodilians, the closest living relatives of birds...
  4. doi request reprint Evolution of digit identity in the three-toed Italian skink Chalcides chalcides: a new case of digit identity frame shift
    Rebecca L Young
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520, USA
    Evol Dev 11:647-58. 2009
    ..This result suggests that changes in of digit identity might be a more frequent consequence of digit reduction than previously assumed...
  5. doi request reprint Frame-shifts of digit identity in bird evolution and Cyclopamine-treated wings
    Alexander O Vargas
    Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT 06520 8106, USA
    Evol Dev 11:163-9. 2009
    ..The serial shift of digit identity toward posterior confirms a mechanistic possibility that was previously inferred from the evolutionary history of birds...
  6. doi request reprint Greater Growth of Proximal Metatarsals in Bird Embryos and the Evolution of Hallux Position in the Grasping Foot
    João Francisco Botelho
    Departamento de Biologia, Laboratorio de Ontogenia y Filogenia, Facultad de Ciencias de la Universidad de Chile, Santiago, RM, Chile
    J Exp Zool B Mol Dev Evol . 2016
    ..It also brings attention to the developmental mechanisms leading to differential growth between epiphyses and their evolutionary consequences...
  7. ncbi request reprint The digits of the wing of birds are 1, 2, and 3. A review
    Alexander O Vargas
    Programa de Anatomía y Biología del Desarrollo, Facultad de Medicina, Universidad de Chile, Independencia 1027, Casilla 70 079 Santiago 7, Santiago, Chile
    J Exp Zool B Mol Dev Evol 304:206-19. 2005
    ....
  8. pmc Molecular development of fibular reduction in birds and its evolution from dinosaurs
    João Francisco Botelho
    Laboratorio de Ontogenia y Filogenia, Departamento de Biologia, Facultad de Ciencias de la Universidad de Chile, Santiago, Chile
    Evolution 70:543-54. 2016
    ..Accordingly, many Mesozoic birds show a fibula that has lost its distal epiphysis, but remains almost as long as the tibia, suggesting that loss of the fibulare preceded and allowed subsequent evolution of great fibulo-tibial disparity. ..
  9. pmc New developmental evidence clarifies the evolution of wrist bones in the dinosaur-bird transition
    João Francisco Botelho
    Laboratorio de Ontogenia y Filogenia, Departamento de Biologia, Facultad de Ciencias, Universidad de Chile, Santiago, Chile
    PLoS Biol 12:e1001957. 2014
    ..The bird wrist provides a modern example of how developmental and paleontological data illuminate each other. Based on all available data, we introduce a new nomenclature for bird wrist ossifications. ..
  10. pmc On the nature of thumbs
    Gunter P Wagner
    Department of Ecology and Evolutionary Biology, Yale University, Prospect Street, New Haven, CT 06520 8106, USA
    Genome Biol 9:213. 2008
    ..This asymmetric expression correlates with independent morphological evolutionary variation of digit 1...
  11. ncbi request reprint Birds have dinosaur wings: The molecular evidence
    Alexander O Vargas
    Programa de Morfología, Facultad de Medicina, Universidad de Chile, Independencia 1027, Casilla 70 079 Santiago 7, Santiago, Chile
    J Exp Zool B Mol Dev Evol 304:86-90. 2005
    ..Our evidence contradicts the long-standing argument that the development of the wing does not support the hypothesis that birds are living dinosaurs...
  12. pmc Skeletal plasticity in response to embryonic muscular activity underlies the development and evolution of the perching digit of birds
    João Francisco Botelho
    Departamento de Biologia, Facultad de Ciencias de la Universidad de Chile and FONDAP Center for Genome Regulation Las Palmeras 3425, Santiago, Chile 7800003
    Sci Rep 5:9840. 2015
    ..We hypothesize on how delayed maturation may have increased plasticity, facilitating muscular twisting. Our experimental results emphasize the importance of embryonic muscular activity in the evolutionary origin of a crucial adaptation. ..
  13. pmc Bird embryos uncover homology and evolution of the dinosaur ankle
    Luis Ossa-Fuentes
    Departamento de Biologia, Laboratorio de Ontogenia y Filogenia, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425, Nunoa, Santiago 7800003, Chile
    Nat Commun 6:8902. 2015
    ..The ASC originated in early dinosaurs along changes to upright posture and locomotion, revealing an intriguing combination of functional innovation and reversion in its evolution. ..
  14. pmc Cortical cytasters: a highly conserved developmental trait of Bilateria with similarities to Ctenophora
    Miguel Salinas-Saavedra
    Laboratory of Ontogeny and Phylogeny, Department of Biology, Faculty of Science, University of Chile, Las Palmeras, Nunoa, Casilla 653, Santiago, Chile
    Evodevo 2:23. 2011
    ..They become associated with several cytoplasmic components, and participate in the reorganization of cortical cytoplasm after fertilization, patterning the antero-posterior and dorso-ventral body axes...
  15. ncbi request reprint How ancient is the adult swimming capacity in the lineage leading to Euchordates?
    Alexander O Vargas
    Departamento de Anatomía y Biología del Desarrollo, Facultad de Medicina, Universidad de Chile, Independencia 1027, Casilla 70 079 Santiago 7, Santiago, Chile
    Evol Dev 7:171-4. 2005