Gilberto Vargas-Alarcon

Summary

Publications

  1. doi request reprint The interleukin 6 -572 G>C (rs1800796) polymorphism is associated with the risk of developing acute coronary syndrome
    José Manuel Fragoso
    Department of Molecular Biology and Cardiovascular Disease s Genomic and Proteomic Study Group, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Genet Test Mol Biomarkers 14:759-63. 2010
  2. pmc Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population
    Diana Torres-García
    Department of Immunolgy, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Tlalpan 4502, Mexico City, 14080, Mexico
    J Transl Med 11:220. 2013
  3. pmc Detection of IS6110 and HupB gene sequences of Mycobacterium tuberculosis and bovis in the aortic tissue of patients with Takayasu's arteritis
    Maria Elena Soto
    Department of Physiology, National Institute of Cardiology Ignacio Chavez, Juan Badiano No 1, Colonia Seccion XVI, 14080 Mexico DF, Mexico
    BMC Infect Dis 12:194. 2012
  4. ncbi request reprint Class II allele and haplotype frequencies in Mexican systemic lupus erythematosus patients: the relevance of considering homologous chromosomes in determining susceptibility
    G Vargas-Alarcon
    Cellular Biology Section, Physiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, Mexico
    Hum Immunol 62:814-20. 2001
  5. ncbi request reprint Angiotensin-I-converting enzyme (ACE) insertion/deletion polymorphism in Mexican patients with coronary artery disease. Association with the disease but not with lipid levels
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiología Ignacio Chávez México City, Mexico
    Exp Mol Pathol 81:131-5. 2006
  6. ncbi request reprint [Physiopathogenesis of hypertension]
    Gilberto Vargas Alarcon
    Departamento de Fisiologia, Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, DF Mexico
    Arch Cardiol Mex 76:S157-60. 2006
  7. ncbi request reprint Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with spondyloarthritis
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Hum Immunol 67:826-32. 2006
  8. ncbi request reprint A deletion in the PRKAR1A gene is associated with Carney complex
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, DF Mexico
    J Pediatr Endocrinol Metab 21:705-9. 2008
  9. ncbi request reprint HLA genes in Mexican Teeneks: HLA genetic relationship with other worldwide populations
    Gilberto Vargas-Alarcon
    Department of Physiology and Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, 14080 Mexico City, Mexico
    Mol Immunol 43:790-9. 2006
  10. ncbi request reprint [Genetic polymorphisms in cardiovascular diseases. The experience in the National Institute of Cardiology "Ignacio Chávez"]
    Gilberto Vargas Alarcon
    Departamento de Fisiologia, Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, DF
    Arch Cardiol Mex 77:S4-88-93. 2007

Collaborators

Detail Information

Publications99

  1. doi request reprint The interleukin 6 -572 G>C (rs1800796) polymorphism is associated with the risk of developing acute coronary syndrome
    José Manuel Fragoso
    Department of Molecular Biology and Cardiovascular Disease s Genomic and Proteomic Study Group, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Genet Test Mol Biomarkers 14:759-63. 2010
    ..The aim of the present study was to evaluate the role of INF-γ and IL-6 gene polymorphisms as susceptibility markers for acute coronary syndromes (ACS) in a group of Mexican patients...
  2. pmc Variants in toll-like receptor 9 gene influence susceptibility to tuberculosis in a Mexican population
    Diana Torres-García
    Department of Immunolgy, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Tlalpan 4502, Mexico City, 14080, Mexico
    J Transl Med 11:220. 2013
    ..Our objective was to determine the influence of TLRs polymorphisms in the susceptibility to develop tuberculosis (TB) in Amerindian individuals from a rural area of Oaxaca, Mexico with high TB incidence...
  3. pmc Detection of IS6110 and HupB gene sequences of Mycobacterium tuberculosis and bovis in the aortic tissue of patients with Takayasu's arteritis
    Maria Elena Soto
    Department of Physiology, National Institute of Cardiology Ignacio Chavez, Juan Badiano No 1, Colonia Seccion XVI, 14080 Mexico DF, Mexico
    BMC Infect Dis 12:194. 2012
    ..tuberculosis and M. bovis. Our objective was to search the presence of IS6110 and HupB genes in aorta of patients with TA...
  4. ncbi request reprint Class II allele and haplotype frequencies in Mexican systemic lupus erythematosus patients: the relevance of considering homologous chromosomes in determining susceptibility
    G Vargas-Alarcon
    Cellular Biology Section, Physiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, Mexico
    Hum Immunol 62:814-20. 2001
    ....
  5. ncbi request reprint Angiotensin-I-converting enzyme (ACE) insertion/deletion polymorphism in Mexican patients with coronary artery disease. Association with the disease but not with lipid levels
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiología Ignacio Chávez México City, Mexico
    Exp Mol Pathol 81:131-5. 2006
    ..Our data suggest that genetic variation at the ACE is a genetic factor related with the susceptibility to coronary artery disease in the Mexican Mestizo population...
  6. ncbi request reprint [Physiopathogenesis of hypertension]
    Gilberto Vargas Alarcon
    Departamento de Fisiologia, Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, DF Mexico
    Arch Cardiol Mex 76:S157-60. 2006
    ..On the other hand, the hereditary nature of this disease has been well established in many familial studies The quantitative contribution of genetic factors to blood pressure variance is estimated to be about 30%...
  7. ncbi request reprint Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with spondyloarthritis
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Hum Immunol 67:826-32. 2006
    ..The present study demonstrates that TNF-alpha -308 polymorphism appears to be associated with the genetic susceptibility U-SpA. The association seems independent of the susceptibility conferred by the HLA-B27 in this group of patients...
  8. ncbi request reprint A deletion in the PRKAR1A gene is associated with Carney complex
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, DF Mexico
    J Pediatr Endocrinol Metab 21:705-9. 2008
    ..In Western blot analyses only full-length protein was present without any evidence of truncated product. These data suggest that the mutant allele might be a null allele due to degradation of the mutant mRNA via nonsense-mediated decay...
  9. ncbi request reprint HLA genes in Mexican Teeneks: HLA genetic relationship with other worldwide populations
    Gilberto Vargas-Alarcon
    Department of Physiology and Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, 14080 Mexico City, Mexico
    Mol Immunol 43:790-9. 2006
    ....
  10. ncbi request reprint [Genetic polymorphisms in cardiovascular diseases. The experience in the National Institute of Cardiology "Ignacio Chávez"]
    Gilberto Vargas Alarcon
    Departamento de Fisiologia, Grupo de Estudio en Genómica y Proteómica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, DF
    Arch Cardiol Mex 77:S4-88-93. 2007
    ..The revision discusses recently published data of polymorphic markers associated with cardiovascular disease in the Mexican population...
  11. ncbi request reprint Association study of LMP gene polymorphisms in Mexican patients with spondyloarthritis
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Hum Immunol 65:1437-42. 2004
    ..05). The data suggest that, besides HLA-B27, LMP2 genotypes are also involved in the genetic susceptibility to develop AS in Mexicans. Furthermore, the age at onset of this disease might also be influenced by genotypes of this gene...
  12. ncbi request reprint Comparative study of the residues 63 and 67 on the HLA-B molecule in patients with Takayasu's Arteritis
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, Col Seccion XVI, Tlalpan 14080, Mexico
    Immunol Lett 96:225-9. 2005
    ..016, OR = 0.13). These data corroborate the participation of positions 63 and 67 in the genetic susceptibility to TA and explain the high heterogeneity of alleles associated with the disease in several populations...
  13. doi request reprint Distribution of HLA class II alleles and haplotypes in Mexican Mestizo population: comparison with other populations
    Gilberto Vargas-Alarcon
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Immunol Invest 39:268-83. 2010
    ..In summary, the HLA class II haplotype frequencies demonstrated the tri-racial component existing in Mexican Mestizos...
  14. doi request reprint HLA-class II genes in Mexican Amerindian Mayas: relatedness with Guatemalan Mayans and other populations
    Gilberto Vargas-Alarcon
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Immunol Invest 40:101-11. 2011
    ..The data corroborate the restricted polymorphism of HLA-DRB1 and DQB1 alleles and the high frequency of HLA-DRB1*04 and HLA-DQB1*0302 in Mayans from Mexico...
  15. ncbi request reprint Distribution of HLA-B alleles in Mexican Amerindian populations
    Gilberto Vargas-Alarcon
    Physiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Immunogenetics 54:756-60. 2003
    ..In spite of the restriction in this polymorphism, differences in frequencies of HLA-B alleles could be helpful in distinguishing each of these populations...
  16. ncbi request reprint [Acute coronary syndrome. Physiopathology and genetics]
    Gilberto Vargas-Alarcon
    Departamento de Biologia Molecular, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, DF
    Rev Invest Clin 63:64-74. 2011
    ..However, in some cases inconsistent results in different populations have been reported. In this review the physiopathogenesis and the role of several candidate genes involved in the pathogenesis of ACS are discussed...
  17. ncbi request reprint LMP2 and LMP7 gene polymorphism in Mexican populations: Mestizos and Amerindians
    G Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Genes Immun 3:373-7. 2002
    ....
  18. pmc Effect of HLA-B and HLA-DR genes on susceptibility to and severity of spondyloarthropathies in Mexican patients
    G Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico DF, Mexico
    Ann Rheum Dis 61:714-7. 2002
    ..To investigate the role of HLA-B and HLA-DR genes as contributors to genetic susceptibility and clinical expression of the spondyloarthropathies (SpA) in the Mexican population...
  19. ncbi request reprint Polymorphism and distribution of HLA-DR2 alleles in Mexican populations
    G Vargas-Alarcon
    Cellular Biology Section, Physiology Department, Instituto Nacional de la Nutricion Salvador Zubiran, D F, Mexico, Mexico
    Hum Immunol 62:286-91. 2001
    ....
  20. pmc Heat shock protein 70 gene polymorphisms in Mexican patients with spondyloarthropathies
    G Vargas-Alarcon
    Cellular Biology Section, Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, Mexico DF, Mexico
    Ann Rheum Dis 61:48-51. 2002
    ..To investigate the role of HSP70 genes as contributors to genetic susceptibility of the spondyloarthropathies (SpA) in the Mexican population...
  21. ncbi request reprint Immunogenetics and clinical aspects of Takayasu's arteritis patients in a Mexican Mestizo population
    G Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Clin Exp Rheumatol 19:439-43. 2001
    ..The aim of the present work was to study the association between HLA alleles and Takayasu's arteritis in Mexican Mestizo patients...
  22. doi request reprint Tumor necrosis factor alpha and interleukin 10 promoter polymorphisms in Mexican patients with restenosis after coronary stenting
    Marco Antonio Martínez-Ríos
    Interventional Cardiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Biochem Genet 47:707-16. 2009
    ..001, OR = 0.199) and the -819 TT genotype (P = 0.037, OR = 0.391). These results suggest the IL-10 -819 TT genotype has a protective role against in-stent restenosis...
  23. ncbi request reprint Angiotensin-converting enzyme gene (ACE) insertion/deletion polymorphism in Mexican populations
    Gilberto Vargas-Alarcon
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan 14080, Mexico DF, Mexico
    Hum Biol 75:889-96. 2003
    ....
  24. ncbi request reprint Origin of Mexican Nahuas (Aztecs) according to HLA genes and their relationships with worldwide populations
    Gilberto Vargas-Alarcon
    Department of Physiology and Grupo de Estudio de Genomica y Proteomica en Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, 14080 Mexico City, Mexico
    Mol Immunol 44:747-55. 2007
    ..This suggests that Nahua language (Nahuatl) may have been imposed to scattered groups throughout Mexico; otherwise Aztecs may have been living in Mexico long before their postulated immigration in the XII century AD...
  25. doi request reprint Human leukocyte antigens I and II haplotypes associated with human papillomavirus 16-positive invasive cervical cancer in Mexican women
    Dulce M Hernández-Hernández
    Department of Epidemiology, Medical Research Unit in Oncology Diseases, Epidemiological Research and Health Services Unit Oncology Hospital, Centro Medico Siglo XXI, Instituto Mexicano del Seguro Social, Av Cuauhtemoc 330, Mexico City, Mexico
    Int J Gynecol Cancer 19:1099-106. 2009
    ..These results support the hypothesis that some HLA class I and II haplotypes could be involved with susceptibility for developing CC...
  26. ncbi request reprint Cytochrome P4501A1 polymorphisms in the Amerindian and Mestizo populations of Mexico
    José Manuel Fragoso
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Cell Biochem Funct 23:189-93. 2005
    ..Our data could be helpful in understanding the distribution of these polymorphisms and in clarifying their roles as genetic and evolution markers in Amerindian populations...
  27. ncbi request reprint MHC class II alleles in Mexican patients with rheumatic heart disease
    Guadalupe Hernández-Pacheco
    Departments of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano No 1, Tlalpan 14080, Mexico City, Mexico
    Int J Cardiol 92:49-54. 2003
    ..Thus, the aim of the present study was to investigate the role of class II alleles in the genetic susceptibility to RHD in Mexican patients and establish the relationship of these alleles with the pattern of valve damage...
  28. pmc Serum magnesium is inversely associated with coronary artery calcification in the Genetics of Atherosclerotic Disease (GEA) study
    Rosalinda Posadas-Sanchez
    Departamento de Endocrinologia, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, Seccion XVI, Mexico City, 14080, Mexico
    Nutr J 15:22. 2016
    ..Serum magnesium is inversely associated to coronary artery calcification (CAC) in patients with chronic kidney disease. There is little information on this association in a general healthy population...
  29. ncbi request reprint MHC class I and class II genes in Mexican patients with Chagas disease
    David Cruz-Robles
    Department of Pathology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico DF, Mexico
    Hum Immunol 65:60-5. 2004
    ..HLA-DR4 and HLA-B39 could be associated directly with the infection by T. cruzi, whereas, HLA-DR16 could be marker of susceptibility to heart damage and HLA-A68 might confer protection to develop cardiomyopathy...
  30. doi request reprint Association of adrenergic receptor gene polymorphisms with different fibromyalgia syndrome domains
    Gilberto Vargas-Alarcon
    National Institute of Cardiology Ignacio Chavez, Tlalpan, Mexico City, Mexico
    Arthritis Rheum 60:2169-73. 2009
    ..We undertook this study to correlate alpha-AR and beta-AR gene polymorphisms with the presence of FM and with different domains of the FM syndrome as measured by the Fibromyalgia Impact Questionnaire (FIQ)...
  31. doi request reprint The MHC2TA 1614 C>G gene polymorphism is associated with risk of developing acute coronary syndrome
    Gilberto Vargas-Alarcon
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Mol Immunol 55:424-8. 2013
    ..The aim of the present study was to evaluate the role of MHC2TA gene polymorphisms as susceptibility markers for acute coronary syndrome (ACS)...
  32. ncbi request reprint Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with rheumatic heart disease
    Guadalupe Hernández-Pacheco
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano No 1, Tlalpan 14080, Mexico City, Mexico
    J Autoimmun 21:59-63. 2003
    ..The data demonstrate that RHD is associated with TNF-alpha polymorphisms in the Mexican population; however, these polymorphisms do not have relation with the valve damage...
  33. ncbi request reprint Matrix gamma-carboxyglutamic acid protein (MGP) G-7A and T-138C gene polymorphisms in Indian (Mayo and Teenek) and Mestizo populations from Mexico
    Guadalupe Hernández-Pacheco
    Department of Physiology and Grupo de Estudio en Genómica y Proteómica de Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano No 1, Tlalpan 14080, Mexico City, Mexico
    Hum Biol 77:385-91. 2005
    ..For the T-138C genotype, we found differences among the Mexicans. This study could help to define the significance of MGP polymorphisms as genetic markers in Amerindian populations...
  34. ncbi request reprint Beta1-adrenergic receptor gene polymorphisms in Mexican patients with idiopathic dilated cardiomyopathy
    José Manuel Fragoso
    Department of Physiology, Cardiovascular Disease s Genomic and Proteomic Study Group, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan 14080, Mexico City, Mexico
    Exp Mol Pathol 80:279-82. 2006
    ..16) and *Arg/*Gly genotype (pC = 0.027, OR = 2.70) in the group of IDC patients when compared to healthy controls. The data suggest that Arg389Gly polymorphism could be involved in the genetic susceptibility to develop IDC in Mexicans...
  35. doi request reprint Interleukin 1 receptor antagonist polymorphisms are associated with the risk of developing acute coronary syndrome in Mexicans
    José Manuel Fragoso
    Department of Molecular Biology and Cardiovascular Disease s Genomic and Proteomic Study Group, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Immunol Lett 133:106-11. 2010
    ..Patients with ACS showed increased frequency of "T1C" haplotype when compared to healthy controls. The results suggest that IL-1RN gene polymorphisms could be involved in the risk of developing ACS in Mexican individuals...
  36. doi request reprint The Srb1+1050T allele is associated with metabolic syndrome in children but not with cholesteryl ester plasma concentrations of high-density lipoprotein subclasses
    Minerva Juárez-Meavepeña
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Metab Syndr Relat Disord 10:110-6. 2012
    ..However, the possible contribution of SR-BI has not been specifically explored in this kind of patients...
  37. doi request reprint The TGF-B1 and IL-10 gene polymorphisms are associated with risk of developing silent myocardial ischemia in the diabetic patients
    Miguel Cruz
    Medical Biochemistry Unit of the Specialities Hospital, Centro Médico Nacional Siglo XXI Instituto Mexicano del Seguro Social, Mexico City, Mexico
    Immunol Lett 156:18-22. 2013
    ..In our study, it was possible to distinguish two protective haplotypes in TGF-β1 for SMI development. ..
  38. doi request reprint The interleukin 1B-511 polymorphism is associated with the risk of developing restenosis after coronary stenting in Mexican patients
    Emma Miranda-Malpica
    Interventional Cardiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Hum Immunol 69:116-21. 2008
    ..The results suggest that IL-1B-511 polymorphism could be involved in the risk of developing restenosis after coronary stent placement...
  39. ncbi request reprint Tumor necrosis factor-alpha promoter polymorphism in Mexican patients with Chagas' disease
    Jose Manuel Rodriguez-Perez
    Physiology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Immunol Lett 98:97-102. 2005
    ..The present study demonstrates that Chagas' disease is associated with TNF-alpha polymorphisms in the Mexican population. The TNF-308 T2 allele could be directly involved in the genetic susceptibility to the chronic phase of the disease...
  40. ncbi request reprint Clinical and genetic heterogeneity in Mexican patients with ulcerative colitis
    Jesus K Yamamoto-Furusho
    Department of Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Tlalpan, Mexico
    Hum Immunol 64:119-23. 2003
    ..HLA-DR15 distinguishes a subgroup of patients with extensive colitis and the HLA-DRB1*0103 allele distinguishes a subgroup of severe form of disease that might require surgical management...
  41. doi request reprint Apolipoprotein E polymorphisms in Mexican patients with coronary artery disease
    Ricardo Gamboa
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Clin Chem Lab Med 46:481-5. 2008
    ..Thus, the purpose of this study was to investigate the association of apolipoprotein E polymorphisms with coronary artery disease and with plasma lipid levels in a group of Mexican Mestizo patients...
  42. doi request reprint Genetic admixture and diversity estimations in the Mexican Mestizo population from Mexico City using 15 STR polymorphic markers
    Teresa Juarez-Cedillo
    Epidemiological Research and Health Services Unit, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico
    Forensic Sci Int Genet 2:e37-9. 2008
    ..They should also be helpful in genetics, population evolution, forensic and paternity testing...
  43. ncbi request reprint MHC class II genes in Mexican patients with idiopathic dilated cardiomyopathy
    Jose Manuel Rodriguez-Perez
    Department of Physiology, Cardiovascular Disease s Genomic and Proteomic Study Group, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan 14080, Mexico City, Mexico
    Exp Mol Pathol 82:49-52. 2007
    ..03, OR=0.26) and HLA-DQB1*0201 (pC=0.04, OR=0.41). These data suggest that variation in class II HLA alleles could be a genetic factor involved in the susceptibility to IDC of the Mexican Mestizo population...
  44. ncbi request reprint HLA-DR association with the genetic susceptibility to develop ashy dermatosis in Mexican Mestizo patients
    Marisol Carrillo Correa
    Department of Dermatology, Hospital General Manuel Gea Gonzalez, Tlalpan, Mexico
    J Am Acad Dermatol 56:617-20. 2007
    ..Ashy dermatosis, also known as erythema dyschromicum perstans, is an acquired benign disease, characterized by blue-gray pigment patches with erythematous borders. The cause is still unclear, but probably has an immunologic basis...
  45. pmc Single nucleotide polymorphisms of the angiotensin-converting enzyme (ACE) gene are associated with essential hypertension and increased ACE enzyme levels in Mexican individuals
    Nancy Martínez-Rodríguez
    Molecular Biology Department, Instituto Nacional de Cardiología Ignacio Chávez INCICH, Mexico City, Mexico
    PLoS ONE 8:e65700. 2013
    ..To explore the role of the ACE gene polymorphisms in the risk of essential hypertension in Mexican Mestizo individuals and evaluate the correlation between these polymorphisms and the serum ACE levels...
  46. doi request reprint The HIF1A rs2057482 polymorphism is associated with risk of developing premature coronary artery disease and with some metabolic and cardiovascular risk factors. The Genetics of Atherosclerotic Disease (GEA) Mexican Study
    Alberto Lopez-Reyes
    Molecular Synovioanalisis Laboratory, Instituto Nacional de Rehabilitacion, Mexico City, Mexico
    Exp Mol Pathol 96:405-10. 2014
    ..009) and HDL-C levels (P = 0.04) in healthy controls. The results suggest that HIF1A rs2057482 polymorphism is involved in the risk of developing CAD and is associated with some metabolic parameters and cardiovascular risk factors...
  47. pmc Single nucleotide polymorphisms within LIPA (Lysosomal Acid Lipase A) gene are associated with susceptibility to premature coronary artery disease. a replication in the genetic of atherosclerotic disease (GEA) Mexican study
    Gilberto Vargas-Alarcon
    Department of Molecular Biology, Instituto Nacional de Cardiología Ignacio, Chávez, Mexico City, Mexico
    PLoS ONE 8:e74703. 2013
    ..The aim of the present study was to replicate this association in an independent population with a different genetic background...
  48. ncbi request reprint Beta1 adrenergic receptor polymorphisms Arg389Gly and Ser49Gly in the Amerindian and Mestizo populations of Mexico
    José Manuel Fragoso
    Department of Physiology and Grupo de Estudio en Genómica y Proteómica de Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano No 1, Tlalpan 14080, Mexico City, Mexico
    Hum Biol 77:515-20. 2005
    ..Mayos present the highest frequency for the *Gly allele. The knowledge of the distribution of these alleles could help define the significance of these polymorphisms as genetic susceptibility markers in Amerindian populations...
  49. ncbi request reprint Distribution of paraoxonase PON1 gene polymorphisms in Mexican populations. Its role in the lipid profile
    Ricardo Gamboa
    Department of Physiology and Grupo de Estudio en Genómica y Proteómica de Enfermedades Cardiovasculares, Instituto Nacional de Cardiología Ignacio Chávez Juan Badiano No 1, Tlalpan 14080, Mexico City, Mexico
    Exp Mol Pathol 80:85-90. 2006
    ..The present data could be helpful to understand the distribution of these polymorphisms and its role as genetic and evolutive markers in the Amerindian populations...
  50. ncbi request reprint Association between IL-1B and IL-1RN gene polymorphisms and Chagas' disease development susceptibility
    David Cruz-Robles
    Department of Molecular Biology and Cardiovascular Disease s Genomic and Proteomic Study Group, Instituto Nacional de Cardiologia, Ignacio Chavez, Mexico City, Mexico
    Immunol Invest 38:231-9. 2009
    ..0018; OR = 16.74) and healthy individuals (pC = 0.011; OR = 3.6). There is an evident association between the IL1RN.4 polymorphism, T. cruzi infection and CCC development...
  51. doi request reprint Alleles and haplotypes of the interleukin 10 gene polymorphisms are associated with risk of developing acute coronary syndrome in Mexican patients
    José Manuel Fragoso
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Cytokine 55:29-33. 2011
    ..The results suggest that IL-10 gene polymorphisms could be involved in the risk of developing ACS in the Mexican population...
  52. pmc A SCN9A gene-encoded dorsal root ganglia sodium channel polymorphism associated with severe fibromyalgia
    Gilberto Vargas-Alarcon
    Department of Molecular Biology, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico
    BMC Musculoskelet Disord 13:23. 2012
    ..The aim of this study was to search for an association between fibromyalgia and several SCN9A sodium channels gene polymorphisms...
  53. ncbi request reprint HLA class I and class II haplotypes in admixed families from several regions of Mexico
    Rodrigo Barquera
    Molecular Genetics Laboratory, ENAH, Mexico City, Mexico
    Mol Immunol 45:1171-8. 2008
    ..Our results are important for future comparative genetic studies of different Mexican ethnic groups with special relevance to disease association and transplantation studies...
  54. pmc HLA class I and class II conserved extended haplotypes and their fragments or blocks in Mexicans: implications for the study of genetic diversity in admixed populations
    Joaquin Zuniga
    Department of Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico
    PLoS ONE 8:e74442. 2013
    ..This work will help as a reference to improve future studies in Mexicans regarding allotransplantation, immune responses and disease associations. ..
  55. doi request reprint The -974C>A (rs3087459) gene polymorphism in the endothelin gene (EDN1) is associated with risk of developing acute coronary syndrome in Mexican patients
    Gilberto Vargas-Alarcon
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Gene 542:258-62. 2014
    ..In this case, the adjusted OR was 1.73 for the AT haplotype (Pc=0.0018). In summary, resulting data suggest that the END1-914 C>A gene polymorphism could be involved in the risk of developing ACS in Mexican individuals...
  56. doi request reprint Normal HDL-apo AI turnover and cholesterol enrichment of HDL subclasses in New Zealand rabbits with partial nephrectomy
    Paola Toledo-Ibelles
    Molecular Biology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico D F
    Metabolism 62:492-8. 2013
    ..Here, we aimed at determining the effects of a renal mass reduction on HDL size distribution, lipid content, and apo AI turnover...
  57. doi request reprint The interleukin-1 gene cluster polymorphisms are associated with Takayasu's arteritis in Mexican patients
    María Elena Soto López
    Department of Immunology, National Cardiology Institute Ignacio Chávez, Mexico City, Mexico
    J Interferon Cytokine Res 33:369-75. 2013
    ..IL-1B and IL-1RN gene polymorphisms could be involved in the risk of developing TA in the Mexican population. These associations were independent of the affected vessels. ..
  58. ncbi request reprint Comparison distribution of HLA-B alleles in mexican patients with takayasu arteritis and tuberculosis
    Maria Elena Soto
    Department of Immunology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Hum Immunol 68:449-53. 2007
    ..TA was characterized by HLA-B39, -B44, and -B52, pulmonary Tb by HL-B35 and extrapulmonary Tb by HLA-B39 and -B40. This preliminary study suggests a difference in the distribution of HLA-B alleles in patients with TA and Tb...
  59. doi request reprint Association of angiotensin II type 1-receptor gene polymorphisms with the risk of developing hypertension in Mexican individuals
    Nancy Martínez-Rodríguez
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    J Renin Angiotensin Aldosterone Syst 13:133-40. 2012
    ..In the present work, the role of angiotensin II type 1-receptor (AGTR1) gene polymorphisms as susceptibility markers for hypertension was evaluated...
  60. doi request reprint Increased HDL Size and Enhanced Apo A-I Catabolic Rates Are Associated With Doxorubicin-Induced Proteinuria in New Zealand White Rabbits
    Victoria López-Olmos
    Molecular Biology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, Section XVI, 14080, Mexico D F, Mexico
    Lipids 51:311-20. 2016
    ..Proteinuria was also connected to an alteration in HDL subclass lipids, apolipoprotein content of HDL, high paraoxonase-1 activity, and a rise in the fractional catabolic rate of the [(131)I]-apo A-I...
  61. doi request reprint Monocyte chemoattractant protein-1 gene (MCP-1) polymorphisms are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study
    Javier Angeles-Martínez
    Departments of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico Electronic address
    Immunol Lett 167:125-30. 2015
    ..The four MCP-1 polymorphisms were in high linkage disequilibrium and one haplotype was significantly associated with risk of developing premature CAD. ..
  62. pmc Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia
    Gilberto Vargas-Alarcon
    National Institute of Cardiology, Juan Badiano 1, Mexico City 14080, Mexico
    Arthritis Res Ther 9:R110. 2007
    ..This association was not observed in Mexican patients. Studies with a larger sample size are needed in order to verify or amend these preliminary results...
  63. ncbi request reprint Distribution of class I and class III MHC antigens in the Tarasco Amerindians
    Francisco Loeza
    Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    Hum Immunol 63:143-8. 2002
    ..This information withstands the basis for population genetic analysis and disease association studies in Mexican mestizos...
  64. ncbi request reprint Polymorphisms in the promoter region of tumor necrosis factor alpha (TNF-alpha) and the HLA-DRB1 locus in Mexican mestizo patients with ulcerative colitis
    Jesus K Yamamoto-Furusho
    Department of Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, DF, Mexico
    Immunol Lett 95:31-5. 2004
    ..In conclusion, this clinical differential pattern of association distinguished in two neighboring loci within the MHC region suggest an independent role of the TNF locus in the genetic susceptibility to develop UC...
  65. ncbi request reprint The matrix metalloproteinase 2-1575 gene polymorphism is associated with the risk of developing myocardial infarction in Mexican patients
    Nonanzit Pérez-Hernández
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    J Atheroscler Thromb 19:718-27. 2012
    ..Was to evaluate the role of seven matrix metalloproteinase (MMP) polymorphisms in the genetic susceptibility to develop myocardial infarction in Mexican individuals...
  66. doi request reprint The T29C polymorphism of the transforming growth factor-β1 (TGF-β1) gene is associated with genetic susceptibility to acute coronary syndrome in Mexican patients
    José Manuel Fragoso
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Cytokine 58:380-3. 2012
    ..The results suggest that TGF-β1 T29C gene polymorphism could be involved in the risk of developing ACS in Mexican individuals...
  67. doi request reprint Reduction of serum lipids by soy protein and soluble fiber is not associated with the ABCG5/G8, apolipoprotein E, and apolipoprotein A1 polymorphisms in a group of hyperlipidemic Mexican subjects
    Nimbe Torres
    Depto de Fisiología de la Nutrición, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico, Mexico
    Nutr Res 29:728-35. 2009
    ..3% had the ApoE (3/4) polymorphism. Independently of genotype, the combination of cholesterol-lowering foods in an LSF diet significantly reduced serum TC and TG in Mexican hypercholesterolemic subjects...
  68. doi request reprint No association found between the insertion/deletion of a 287-bp alu repeat sequence within intron 16 of the angiotensin-I-converting enzyme (ACE) gene in Mexican patients and binary restenosis after coronary stenting
    Marco Antonio Martínez-Ríos
    Interventional Cardiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Clin Chim Acta 397:65-7. 2008
    ....
  69. pmc Interleukin-17A gene haplotypes are associated with risk of premature coronary artery disease in Mexican patients from the Genetics of Atherosclerotic Disease (GEA) study
    Gilberto Vargas-Alarcon
    Departments of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    PLoS ONE 10:e0114943. 2015
    ..The aim of the present study was to evaluate the role of IL-17A gene polymorphisms as susceptibility markers for CAD in the Mexican population...
  70. doi request reprint Low concentrations of phospholipids and plasma HDL cholesterol subclasses in asymptomatic subjects with high coronary calcium scores
    Cynthia García-Sánchez
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico
    Atherosclerosis 238:250-5. 2015
    ..To determine whether HDL size distribution and HDL subclasses are associated with coronary calcium scores...
  71. doi request reprint Association of the suppressor of cytokine signaling 1 (SOCS1) gene polymorphisms with acute coronary syndrome in Mexican patients
    Gilberto Vargas-Alarcon
    Department of Molecular Biology and Interventional Genetic Study Group Instituto Nacional de Cardiología Ignacio Chávez, Mexico City, Mexico
    Mol Immunol 62:137-41. 2014
    ..In summary, our data suggests that the four studied polymorphisms of the SOCS1 gene play an important role as susceptibility markers for developing ACS...
  72. doi request reprint Haplotypes of the angiotensin-converting enzyme (ACE) gene are associated with coronary artery disease but not with restenosis after coronary stenting
    Marco Antonio Martínez-Ríos
    Interventional Cardiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Exp Mol Pathol 97:166-70. 2014
    ..Haplotypes of the ACE gene could be a genetic factor related to coronary artery disease in the Mexican individuals, but do not support its role as a risk factor for developing restenosis after coronary stenting. ..
  73. pmc Role of the HLA-DQ locus in the development of chronic gastritis and gastric carcinoma in Mexican patients
    Roberto Herrera-Goepfert
    Department of Pathology, Instituto Nacional de Cancerologia, Mexico City, Mexico
    World J Gastroenterol 12:7762-7. 2006
    ..To determine the HLA-DQ locus in Mexican patients with Chronic gastritis and gastric adenocarcinoma...
  74. ncbi request reprint [Alleles of the major histocompatibility system associated with susceptibility to the development of Takayasu's arteritis]
    C Flores-Dominguez
    Departamentos de Biología Celular e Inmunología, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano No 1, Tlalpan 14080, Mexico D F
    Gac Med Mex 138:177-83. 2002
    ....
  75. pmc High resolution human leukocyte antigen (HLA) class I and class II allele typing in Mexican mestizo women with sporadic breast cancer: case-control study
    David Cantu de Leon
    Department of Gynecologic Oncology, Instituto Nacional de Cancerología de México, Mexico City, Mexico
    BMC Cancer 9:48. 2009
    ..HLAAllele-specific interaction has not been well established. Recently, several studies had been conducted in order to do so, but the results are controversial and in some instances contradictory...
  76. doi request reprint Lipid plasma concentrations of HDL subclasses determined by enzymatic staining on polyacrylamide electrophoresis gels in children with metabolic syndrome
    Cynthia García-Sánchez
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, Seccion XVI, 14080 Mexico D F, Mexico
    Clin Chim Acta 412:292-8. 2011
    ..HDL particles of the same size can have different lipid contents in some physiopathological situations. However, little is known about the plasma lipid levels of HDL subclasses when they are separated by their hydrodynamic diameter...
  77. doi request reprint Relationship between the angiotensin I-converting enzyme insertion/deletion (I/D) polymorphism and cardiovascular risk factors in healthy young Mexican women
    Maite Vallejo
    Department of Research Direction, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Genet Test Mol Biomarkers 13:237-42. 2009
    ..The purpose of this study was to identify the CRF patterns associated with the ACE I/D polymorphism in women from different Mexican communities...
  78. doi request reprint MCP-1, RANTES, and SDF-1 polymorphisms in Mexican patients with systemic lupus erythematosus
    Guadalupe Lima
    Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    Hum Immunol 68:980-5. 2007
    ..Our results suggest that MCP-1 polymorphism is moderately associated with the genetic susceptibility to SLE in Mexican individuals. The polymorphisms could be related to specific clinical and laboratory characteristics in these patients...
  79. pmc Distribution of the IL-1RN, IL-6, IL-10, INF-γ, and TNF-α Gene Polymorphisms in the Mexican Population
    Gilberto Vargas-Alarcon
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Genet Test Mol Biomarkers 16:1246-53. 2012
    ..These polymorphisms have been reported in several populations, with important variation in frequency according to the studied population...
  80. doi request reprint The MHC2TA gene polymorphisms are not associated with restenosis after coronary stenting in Mexican patients
    Hilda Delgadillo
    Interventional Genetic Study Group in Cardiovascular Disease s, National Institute of Cardiology Ignacio Chavez, Mexico City, Mexico
    Arch Cardiol Mex 82:208-13. 2012
    ..The aim of this study was to test for association between MHC2TA gene polymorphisms and risk for restenosis after coronary stent placement in a group of Mexican patients...
  81. ncbi request reprint HLA-DR allele frequencies in Mexican mestizos with autoimmune liver diseases including overlap syndromes
    Sergio Zepeda-Gomez
    Department of Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    Immunol Invest 38:276-83. 2009
    ..On the other hand, the gene frequency of HLADR5 was significantly decreased in the total group of patients as compared to healthy controls suggesting a protective role of this allele for developing autoimmune liver disease...
  82. doi request reprint PDCD1 gene polymorphisms in different Mexican ethnic groups and their role in the susceptibility to hypersensitivity pneumonitis
    Joaquin Zuniga
    Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, 14080, Mexico
    Clin Biochem 43:929-31. 2010
    ..This study was conducted to test whether the PD1.3 and PD1.5 polymorphisms are associated with HP in Mexican patients and to explore the distribution of these polymorphisms in different Mexican ethnic groups...
  83. ncbi request reprint The risk of developing cervical cancer in Mexican women is associated to CYP1A1 MspI polymorphism
    Teresa Juarez-Cedillo
    Epidemiological Research and Health Services Unit, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico
    Eur J Cancer 43:1590-5. 2007
    ..These results suggest an important role of the CYP1A1 MspI polymorphism in the risk of developing cervical cancer...
  84. ncbi request reprint [Low paraoxonase and arylesterase plasma activities in Mexican patients with coronary artery disease]
    Ricardo Gamboa
    Departamento de Fisiologia, Instituto Nacional de Cardiologia Ignacio Chavez, DF Mexico
    Arch Cardiol Mex 78:360-8. 2008
    ..To determine the Paraoxonase-1 (PON1) activity as well as its pheno- and genotypes at position 192 in Mexican subjects with diagnosis of coronary heart disease (CHD)...
  85. ncbi request reprint The Arg389Gly beta1-adrenergic receptor gene polymorphism and susceptibility to faint during head-up tilt test
    M F Marquez
    Department of Electrocardiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Europace 9:585-8. 2007
    ..To investigate the association of the Gly389 allele with positive head-up tilt test (HUT) in a Mexican Mestizo population...
  86. doi request reprint Protective role of interleukin-19 gene polymorphisms in patients with ulcerative colitis
    Jesus K Yamamoto-Furusho
    Inflammatory Bowel Disease Clinic, Department of Gastroenterology, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    Hum Immunol 72:1029-32. 2011
    ..The results suggest that IL-19 polymorphisms (rs2243188 and rs2243193) might have a protective role in the development of UC in Mexican individuals...
  87. ncbi request reprint [Influence of alleles and haplotypes of the main histocompatibility complex on the susceptibility to systemic lupus erythematosus in the Mexican population]
    Julio Granados
    Departamento de Inmunología y Reumatología, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico DF
    Gac Med Mex 142:195-9. 2006
    ....
  88. ncbi request reprint Palmitic acid in HDL is associated to low apo A-I fractional catabolic rates in vivo
    Oscar Pérez-Méndez
    Department of Physiology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Clin Chim Acta 378:53-8. 2007
    ..However, little is known about the impact of NEFAs on HDL metabolism. We investigated the effects of one NEFA, the palmitic acid, on HDL structure and catabolism...
  89. ncbi request reprint [Antithrombotic regulation by fibrinolytic system]
    Aurora de la Peña Díaz
    Departamento de Farmacologia, Facultad de Medicina, Universidad Nacional Autonoma de Mexico
    Arch Cardiol Mex 77:S4-82-7. 2007
    ..It is described: the mechanism of activation of plasminogen by their activators as much on the fibrin as in the cells surface; the inhibition of the activators in different metabolic alterations...
  90. doi request reprint Transporter associated with antigen processing (TAP) 1 gene polymorphisms in patients with hypersensitivity pneumonitis
    Arnoldo Aquino-Galvez
    Instituto Nacional de Enfermedades Respiratorias, Tlalpan 4502, Col Seccion XVI, 14080, Mexico City, Mexico
    Exp Mol Pathol 84:173-7. 2008
    ..002, OR=0.07, CI=0.0-0.57). These findings suggest that TAP1 gene polymorphisms are related to HP risk, and highlight the importance of the MHC in the development of this disease...
  91. pmc Protective KIR-HLA interactions for HCV infection in intravenous drug users
    Joaquin Zuniga
    Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City, Mexico
    Mol Immunol 46:2723-7. 2009
    ..These results support the hypothesis that activator signaling, mediated by KIR2DS4, plays a determinant role in the regulation of NK cell antiviral-activity...
  92. doi request reprint Rosiglitazone modifies HDL structure and increases HDL-apo AI synthesis and catabolic rates
    Elizabeth Carreón-Torres
    Department of Molecular Biology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Clin Chim Acta 401:37-41. 2009
    ..Therefore, we determined the effect of rosiglitazone on apo AI turnover, HDL structure, and PON1 plasma activity...
  93. ncbi request reprint HLA-DRB1*08 allele may help to distinguish between type 1 diabetes mellitus and type 2 diabetes mellitus in Mexican children
    Ana L Rodríguez-Ventura
    Department of Pediatric Endocrinology, Hospital Infantil de Mexico, Mexico City, Mexico
    Pediatr Diabetes 8:5-10. 2007
    ..The human leukocyte antigen (HLA)-DR genotype has been associated with T1DM and with T2DM only in adults and in determined cases...
  94. ncbi request reprint Familial collapsing glomerulopathy: clinical, pathological and immunogenetic features
    M Carmen Avila-Casado
    Department of Pathology, Instituto Nacional de CardiologiaIgnacio Chavez, Universidad Nacional Autonoma de Mexico, Mexico DF, Mexico
    Kidney Int 63:233-9. 2003
    ..Until now, the occurrence of CG in a familial pattern has not been reported...
  95. doi request reprint Comparative study of the residues 63 and 67 on the HLA-B molecule in patients with Takayasu's arteritis and tuberculosis
    Gilberto Vargas-Alarcon
    Department of Physiology and Cardiovascular Disease s Genomic and Proteomic Study Group, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Cell Biochem Funct 26:820-3. 2008
    ..7%) did not show similarity at the mentioned positions (p = 0.019). This preliminary study suggests a difference in the distribution of the residues 63 and 67 of the HLA-B alleles in patients with TA and TB...
  96. ncbi request reprint [Clinical guidelines for detection, prevention, diagnosis and treatment of systemic arterial hypertension in Mexico (2008)]
    Martin Rosas
    Departamento de Cardiología Adultos III, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, Mexico DF
    Arch Cardiol Mex 78:S2-5-57. 2008
    ..Also we have approached some aspects related to the hypertensive emergencies and other special situations. In this second version some recommendations are presented for boarding hypertension in children and adolescents...
  97. ncbi request reprint [KCNQ 1 (KvLQT1) missense mutation causing congenital long QT syndrome (Jervell-Lange-Nielsen) in a Mexican family]
    Manlio F Marquez
    Departamento de Electrocardiologia, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, Mexico
    Arch Cardiol Mex 76:257-62. 2006
    ..The Jervell and Lange-Nielsen (JLN) syndrome is the recessive form of the disease and is associated with deafness. Few families with JLN syndrome and genetic studies are reported in the literature...
  98. ncbi request reprint [Pro-inflammatory and anti-inflammatory markers in coronary artery disease and acute ischemic coronary syndrome]
    José Manuel Fragoso-Lona
    Departamento de Biologia Molecular, Grupo de Estudio en Genómica y Proteómica de Enfermedades Cardiovasculares, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, Mexico D F, Mexico
    Arch Cardiol Mex 79:54-62. 2009
    ..The analysis of the markers may be useful for the development of new strategies for coronary disease prevention and treatment. Therefore, we need a well-designed evaluation of these markers before their use in the clinical practice...
  99. ncbi request reprint [Cardiac myxomas and the Carney complex]
    Jesús Vargas-Barrón
    Departamento de Ecocardiografia, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico DF, Mexico
    Rev Esp Cardiol 61:1205-9. 2008
    ..In conclusion, the possible presence of the Carney complex should be investigated in patients with multiple myxomas or with a cardiac myxoma whose location is atypical...