Nico Van Rooijen

Summary

Publications

  1. pmc Monocyte depletion increases local proliferation of macrophage subsets after skeletal muscle injury
    Claude H Cote
    Centre de Recherche du CHUL CHUQ, 2705 Boulevard Laurier, RC 9800 Québec, Quebec, Canada
    BMC Musculoskelet Disord 14:359. 2013
  2. pmc Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures
    Hiromi Kumamaru
    Department of Orthopedic Surgery, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Neuroinflammation 9:116. 2012
  3. pmc Neuroprotective function for ramified microglia in hippocampal excitotoxicity
    Jonathan Vinet
    Department of Neuroscience, Section Medical Physiology, University Medical Center Groningen UMCG, Rijksuniversiteit Groningen RUG, Groningen, The Netherlands
    J Neuroinflammation 9:27. 2012
  4. pmc Resident macrophages influence stem cell activity in the mammary gland
    David E Gyorki
    VBCRC Laboratory, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia
    Breast Cancer Res 11:R62. 2009
  5. ncbi request reprint Liposomes for targeting of antigens and drugs: immunoadjuvant activity and liposome-mediated depletion of macrophages
    Nico Van Rooijen
    Department of Molecular Cell Biology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    J Drug Target 16:529-34. 2008
  6. ncbi request reprint Small artery remodeling and erythrocyte deformability in L-NAME-induced hypertension: role of transglutaminases
    Adrian Pistea
    Department of Medical Physics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Vasc Res 45:10-8. 2008
  7. ncbi request reprint Blood flow-dependent arterial remodelling is facilitated by inflammation but directed by vascular tone
    Erik N T P Bakker
    Department of Medical Physics, Academic Medical Center, Amsterdam, The Netherlands
    Cardiovasc Res 78:341-8. 2008
  8. ncbi request reprint "In vivo" depletion of macrophages by liposome-mediated "suicide"
    Nico Van Rooijen
    Department of Cell and Immunology, Faculty of Medicine, Vrije Universiteit Medical Center, Van de Boechhorststraat 7, 1081 BT Amsterdam, The Netherlands
    Methods Enzymol 373:3-16. 2003
  9. ncbi request reprint Clodronate liposomes: perspectives in research and therapeutics
    Nico Van Rooijen
    Department of Molecular Cell Biology, Research Institute of Immunology and Inflammation, Faculty of Medicine, Vrije Universiteit Van der Boechorststraat, Amsterdam, The Netherlands
    J Liposome Res 12:81-94. 2002
  10. ncbi request reprint Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: possible compensation by macrophage-derived factor XIII
    Erik N T P Bakker
    Department of Medical Physics, Academic Medical Center and Cardiovascular Research Institute Amsterdam, Amsterdam, The Netherlands
    Circ Res 99:86-92. 2006

Collaborators

  • Erik N T P Bakker
  • Ed Vanbavel
  • Gerrit A Meijer
  • Max R Hardeman
  • Claude H Cote
  • Hiromi Kumamaru
  • Jonathan Vinet
  • David E Gyorki
  • Adrian Pistea
  • Steven J Oosterling
  • Machteld M J Polfliet
  • Elise Duchesne
  • David Marsolais
  • Patrice Bouchard
  • Knut Biber
  • Kazuhide Inoue
  • Annette Heinrich
  • Yukihide Iwamoto
  • Kazu Kobayakawa
  • Hirokazu Saiwai
  • Anja Wegner
  • Seiji Okada
  • Hilmar R J van Weering
  • Nieske Brouwer
  • Frank L Heppner
  • Nico Van Rooijen
  • Hendrikus W G M Boddeke
  • Kensuke Kubota
  • Roland E Kälin
  • Marie Liesse Asselin-Labat
  • Jane E Visvader
  • Geoffrey J Lindeman
  • Jos A E Spaan
  • Cornelis W Tuk
  • Sybren Meijer
  • Joost R M van der Sijp
  • Robert H J Beelen
  • Marjolein van Egmond
  • Gerben J van der Bij
  • Evert Van Garderen
  • Ed A Döpp
  • Christine D Dijkstra
  • Timo K van den Berg
  • Esther M L van Kesteren-Hendrikx
  • F van de Veerdonk

Detail Information

Publications13

  1. pmc Monocyte depletion increases local proliferation of macrophage subsets after skeletal muscle injury
    Claude H Cote
    Centre de Recherche du CHUL CHUQ, 2705 Boulevard Laurier, RC 9800 Québec, Quebec, Canada
    BMC Musculoskelet Disord 14:359. 2013
    ..The aims of this study are thus to investigate if proliferation occurs in macrophage subsets within injured skeletal muscles; and to determine if monocyte depletion leads to increased proliferation of macrophages after injury...
  2. pmc Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures
    Hiromi Kumamaru
    Department of Orthopedic Surgery, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    J Neuroinflammation 9:116. 2012
    ..However, this advantage can be hindered by microglial contamination. Although several authors have warned regarding microglial contamination in this system, complete microglial elimination has never been achieved...
  3. pmc Neuroprotective function for ramified microglia in hippocampal excitotoxicity
    Jonathan Vinet
    Department of Neuroscience, Section Medical Physiology, University Medical Center Groningen UMCG, Rijksuniversiteit Groningen RUG, Groningen, The Netherlands
    J Neuroinflammation 9:27. 2012
    ..Resting, ramified microglia are suggested to primarily monitor their environment including synapses. Here, we show an active protective role of ramified microglia in excitotoxicity-induced neurodegeneration...
  4. pmc Resident macrophages influence stem cell activity in the mammary gland
    David E Gyorki
    VBCRC Laboratory, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia
    Breast Cancer Res 11:R62. 2009
    ..Here we have explored a role for macrophages in regulating mammary stem cell (MaSC) activity, by assessing the ability of MaSCs to reconstitute a mammary gland in a macrophage-depleted fat pad...
  5. ncbi request reprint Liposomes for targeting of antigens and drugs: immunoadjuvant activity and liposome-mediated depletion of macrophages
    Nico Van Rooijen
    Department of Molecular Cell Biology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    J Drug Target 16:529-34. 2008
    ..In several cases, organ-specific depletion can be obtained by choosing the right administration route for the clodronate liposomes...
  6. ncbi request reprint Small artery remodeling and erythrocyte deformability in L-NAME-induced hypertension: role of transglutaminases
    Adrian Pistea
    Department of Medical Physics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Vasc Res 45:10-8. 2008
    ..We hypothesized that these alterations depend on transglutaminases, cross-linking enzymes present in the vascular wall, monocytes/macrophages and erythrocytes...
  7. ncbi request reprint Blood flow-dependent arterial remodelling is facilitated by inflammation but directed by vascular tone
    Erik N T P Bakker
    Department of Medical Physics, Academic Medical Center, Amsterdam, The Netherlands
    Cardiovasc Res 78:341-8. 2008
    ..We tested the hypothesis that inflammation facilitates the remodelling response, but that vascular tone determines its direction (inward or outward)...
  8. ncbi request reprint "In vivo" depletion of macrophages by liposome-mediated "suicide"
    Nico Van Rooijen
    Department of Cell and Immunology, Faculty of Medicine, Vrije Universiteit Medical Center, Van de Boechhorststraat 7, 1081 BT Amsterdam, The Netherlands
    Methods Enzymol 373:3-16. 2003
  9. ncbi request reprint Clodronate liposomes: perspectives in research and therapeutics
    Nico Van Rooijen
    Department of Molecular Cell Biology, Research Institute of Immunology and Inflammation, Faculty of Medicine, Vrije Universiteit Van der Boechorststraat, Amsterdam, The Netherlands
    J Liposome Res 12:81-94. 2002
    ....
  10. ncbi request reprint Flow-dependent remodeling of small arteries in mice deficient for tissue-type transglutaminase: possible compensation by macrophage-derived factor XIII
    Erik N T P Bakker
    Department of Medical Physics, Academic Medical Center and Cardiovascular Research Institute Amsterdam, Amsterdam, The Netherlands
    Circ Res 99:86-92. 2006
    ..Adventitial monocytes/macrophages are a source of factor XIII in tTG-null mice and contribute to an alternative, delayed mechanism of inward remodeling when tTG is absent...
  11. ncbi request reprint Liposomes for specific depletion of macrophages from organs and tissues
    Nico Van Rooijen
    Department of Molecular Cell Biology and Immunology, VU University Medical Center, Amsterdam, The Netherlands
    Methods Mol Biol 605:189-203. 2010
    ..In several cases, organ specific depletion can be obtained by choosing the right administration route for the clodronate liposomes...
  12. ncbi request reprint Macrophages direct tumour histology and clinical outcome in a colon cancer model
    Steven J Oosterling
    Department of Surgical Oncology, VU University Medical Center, Amsterdam, The Netherlands
    J Pathol 207:147-55. 2005
    ..The selective inhibition of macrophage functions involved in malignant progression without interfering with cytotoxic ability may therefore identify important new targets for cancer therapy...
  13. ncbi request reprint The role of perivascular and meningeal macrophages in experimental allergic encephalomyelitis
    Machteld M J Polfliet
    Department of Molecular Cell Biology, Faculty of Medicine, Vrije Universiteit, Van der Boechorststraat 7, 1081 BT, Amsterdam, The Netherlands
    J Neuroimmunol 122:1-8. 2002
    ..These observations indicate that PVM and MM play a role during the early stages of EAE development...