Clementina M Van Rijn

Summary

Publications

  1. pmc Neurodegenerative properties of chronic pain: cognitive decline in patients with chronic pancreatitis
    Marijtje L A Jongsma
    Donders Centre for Cognition, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    PLoS ONE 6:e23363. 2011
  2. ncbi request reprint Endocannabinoid system protects against cryptogenic seizures
    Clementina M Van Rijn
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, P O B 9104, 6500 HE Nijmegen, The Netherlands
    Pharmacol Rep 63:165-8. 2011
  3. pmc Decapitation in rats: latency to unconsciousness and the 'wave of death'
    Clementina M Van Rijn
    Department of Biological Psychology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    PLoS ONE 6:e16514. 2011
  4. doi request reprint WAG/Rij rats show a reduced expression of CB₁ receptors in thalamic nuclei and respond to the CB₁ receptor agonist, R(+)WIN55,212-2, with a reduced incidence of spike-wave discharges
    Clementina M Van Rijn
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, The Netherlands
    Epilepsia 51:1511-21. 2010
  5. doi request reprint The learning-oddball paradigm: data of 24 separate individuals illustrate its potential usefulness as a new clinical tool
    Marijtje L A Jongsma
    Donders Institute for Brain, Cognition, and Behavior, DCC, Radboud University Nijmegen, Montessorilaan 3, 6525 HR Nijmegen, The Netherlands
    Clin Neurophysiol 124:514-21. 2013
  6. ncbi request reprint The effects of vigabatrin on spike and wave discharges in WAG/Rij rats
    Brigitte M Bouwman
    NICI Department of Biological Psychology, Radboud University Nijmegen, 6500 HE Nijmegen, The Netherlands
    Epilepsy Res 76:34-40. 2007
  7. ncbi request reprint GABAergic mechanisms in absence epilepsy: a computational model of absence epilepsy simulating spike and wave discharges after vigabatrin in WAG/Rij rats
    Brigitte M Bouwman
    NICI Department of Biological Psychology, Radboud University Nijmegen, PO Box 9104, 6500 HE Nijmegen, The Netherlands
    Eur J Neurosci 25:2783-90. 2007
  8. ncbi request reprint Tracking pattern learning with single-trial event-related potentials
    Marijtje L A Jongsma
    NICI, Department of Biological Psychology, Radboud University, Nijmegen, The Netherlands
    Clin Neurophysiol 117:1957-73. 2006
  9. doi request reprint Event related potentials to digit learning: tracking neurophysiologic changes accompanying recall performance
    Marijtje L A Jongsma
    Donders Institute for Brain, Cognition, and Behavior, DCC, Radboud University Nijmegen, Montessorilaan 3, 6525 HR Nijmegen, The Netherlands
    Int J Psychophysiol 85:41-8. 2012
  10. ncbi request reprint Starting and stopping mechanisms of absence epileptic seizures are revealed by hazard functions
    Eric Maris
    Nijmegen Institute of Cognition and Information NICI, Radboud University Nijmegen, P O Box 9104, 6500 HE Nijmegen, The Netherlands
    J Neurosci Methods 152:107-15. 2006

Detail Information

Publications25

  1. pmc Neurodegenerative properties of chronic pain: cognitive decline in patients with chronic pancreatitis
    Marijtje L A Jongsma
    Donders Centre for Cognition, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    PLoS ONE 6:e23363. 2011
    ..Therefore, early and effective therapeutic interventions might reduce or prevent decline in cognitive performance, thereby improving outcomes and quality of life in these patients...
  2. ncbi request reprint Endocannabinoid system protects against cryptogenic seizures
    Clementina M Van Rijn
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, P O B 9104, 6500 HE Nijmegen, The Netherlands
    Pharmacol Rep 63:165-8. 2011
    ..We hypothesize that an accumulation of micro-injuries in the brain is responsible for these "spontaneous" seizures...
  3. pmc Decapitation in rats: latency to unconsciousness and the 'wave of death'
    Clementina M Van Rijn
    Department of Biological Psychology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands
    PLoS ONE 6:e16514. 2011
    ..This observation might have implications in the discussions on the appropriate time for organ donation...
  4. doi request reprint WAG/Rij rats show a reduced expression of CB₁ receptors in thalamic nuclei and respond to the CB₁ receptor agonist, R(+)WIN55,212-2, with a reduced incidence of spike-wave discharges
    Clementina M Van Rijn
    Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, The Netherlands
    Epilepsia 51:1511-21. 2010
    ..We used WAG/Rij rats to examine whether absence seizures are associated with changes in the expression of type-1 cannabinoid (CB₁) receptors...
  5. doi request reprint The learning-oddball paradigm: data of 24 separate individuals illustrate its potential usefulness as a new clinical tool
    Marijtje L A Jongsma
    Donders Institute for Brain, Cognition, and Behavior, DCC, Radboud University Nijmegen, Montessorilaan 3, 6525 HR Nijmegen, The Netherlands
    Clin Neurophysiol 124:514-21. 2013
    ..Using the learning-oddball paradigm, the aim of the present paper was to determine ERP effects of introducing regularity in individual participants...
  6. ncbi request reprint The effects of vigabatrin on spike and wave discharges in WAG/Rij rats
    Brigitte M Bouwman
    NICI Department of Biological Psychology, Radboud University Nijmegen, 6500 HE Nijmegen, The Netherlands
    Epilepsy Res 76:34-40. 2007
    ..Vigabatrin gradually changed the course of the hazard rates of the SWD durations, suggesting a qualitative GABAergic role in the mechanism(s) underlying the stopping of an ongoing SWD...
  7. ncbi request reprint GABAergic mechanisms in absence epilepsy: a computational model of absence epilepsy simulating spike and wave discharges after vigabatrin in WAG/Rij rats
    Brigitte M Bouwman
    NICI Department of Biological Psychology, Radboud University Nijmegen, PO Box 9104, 6500 HE Nijmegen, The Netherlands
    Eur J Neurosci 25:2783-90. 2007
    ..Based on these results, we suggest that GABAergic neurotransmission in TC cells is actively involved in the SWD termination...
  8. ncbi request reprint Tracking pattern learning with single-trial event-related potentials
    Marijtje L A Jongsma
    NICI, Department of Biological Psychology, Radboud University, Nijmegen, The Netherlands
    Clin Neurophysiol 117:1957-73. 2006
    ..A new 'learning-oddball' paradigm was employed presenting eight random targets (the 'no-pattern') followed by eight regular targets (the 'pattern'). In total, six repetitions of the 'no-pattern' followed by the 'pattern' were presented...
  9. doi request reprint Event related potentials to digit learning: tracking neurophysiologic changes accompanying recall performance
    Marijtje L A Jongsma
    Donders Institute for Brain, Cognition, and Behavior, DCC, Radboud University Nijmegen, Montessorilaan 3, 6525 HR Nijmegen, The Netherlands
    Int J Psychophysiol 85:41-8. 2012
    ..These results, which were discussed in the framework of theories on the functional significance of the P300 amplitude, add to the scarce empirical data on the dynamics of ERP responses in the process of intentional learning...
  10. ncbi request reprint Starting and stopping mechanisms of absence epileptic seizures are revealed by hazard functions
    Eric Maris
    Nijmegen Institute of Cognition and Information NICI, Radboud University Nijmegen, P O Box 9104, 6500 HE Nijmegen, The Netherlands
    J Neurosci Methods 152:107-15. 2006
    ..Initially, this probability is larger with a high GABA level, but gradually it converges to the same constant baseline probability as in the condition with a low GABA level...
  11. ncbi request reprint Expectancy effects on omission evoked potentials in musicians and non-musicians
    Marijtje L A Jongsma
    Department of Biological Psychology, Nijmegen Institute of Cognition and Information, Radboud University Nijmegen, The Netherlands
    Psychophysiology 42:191-201. 2005
    ..Thus, musical training seems to lead to more efficient and more refined processing of auditory temporal patterns...
  12. ncbi request reprint Rhythmic training decreases latency-jitter of omission evoked potentials (OEPs) in humans
    Marijtje L A Jongsma
    NICI Nijmegen Institute of Cognition and Information, Department of Biological Psychology, University of Nijmegen, PO Box 9104, 6500 HE Nijmegen, The Netherlands
    Neurosci Lett 355:189-92. 2004
    ..No group differences in OEPs amplitudes or latencies were observed. However, rhythmic experts showed less latency-jitter of both the OEPs positive wave and of behavioral responses compared with non-musicians...
  13. pmc Anti-epileptogenesis: Electrophysiology, diffusion tensor imaging and behavior in a genetic absence model
    Gilles van Luijtelaar
    Donders Centre for Cognition, Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, The Netherlands Electronic address
    Neurobiol Dis 60:126-38. 2013
    ..The treatment of patients before symptom onset might prevent many of the adverse consequences of chronic epilepsy...
  14. doi request reprint The effect of high-frequency conditioning stimulation of human skin on reported pain intensity and event-related potentials
    Emanuel N van den Broeke
    Department of Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Neurophysiol 108:2276-81. 2012
    ..Recently, it has been proposed that ERPs, at least partly, reflect a saliency detection system. Therefore, the enhanced ERPs might reflect enhanced saliency to potentially threatening stimuli...
  15. ncbi request reprint Auditory event-related potentials in humans and rats: effects of task manipulation
    Anke Sambeth
    Nijmegen Institute of Cognition and Information Department of Biological Psychology, University of Nijmegen, Nijmegen, The Netherlands
    Psychophysiology 40:60-8. 2003
    ..The P3 in rats appeared at 380 ms. We conclude that either the relation between human and rat peak latencies is not linear, or the P3 in rats is not the equivalent of the human P3...
  16. ncbi request reprint Effects of levetiracetam on spike and wave discharges in WAG/Rij rats
    Brigitte M Bouwman
    NICI Department of Biological Psychology, University of Nijmegen, P O Box 9104, 6500 HE Nijmegen, The Netherlands
    Seizure 13:591-4. 2004
    ..Furthermore, the decrease of the SWD peak frequency might support the suggestions that levetiracetam might have a GABAergic mechanism of action...
  17. pmc Neural correlates of heterotopic facilitation induced after high frequency electrical stimulation of nociceptive pathways
    Emanuel N van den Broeke
    Department of Anesthesiology, Pain and Palliative Medicine, Pain and Nociception Neuroscience Research Group, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Mol Pain 7:28. 2011
    ..To this end we measured evoked potentials in response to noxious electrical pinprick-like stimuli applied in the heterotopic skin area before, directly after and 30 minutes after HFS...
  18. doi request reprint Patients with persistent pain after breast cancer treatment show enhanced alpha activity in spontaneous EEG
    Emanuel N van den Broeke
    Donders Institute for Brain, Cognition and Behavior, Radboud University Nijmegen, Nijmegen, The Netherlands
    Pain Med 14:1893-9. 2013
    ....
  19. pmc Altered cortical responsiveness to pain stimuli after high frequency electrical stimulation of the skin in patients with persistent pain after inguinal hernia repair
    Emanuel N van den Broeke
    Department of Anesthesiology, Pain and Palliative Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    PLoS ONE 8:e82701. 2013
    ..The aim of the present study was to investigate whether this enhanced ERP N1 amplitude could be a potential marker for altered cortical sensory processing in patients with persistent pain after surgery...
  20. ncbi request reprint The interaction between vigabatrin and diazepam on the electroencephalogram during active behaviour in rats: an isobolic analysis
    Brigitte M Bouwman
    NICI Department of Biological Psychology, University of Nijmegen, P O Box 9104, 6500 HE Nijmegen, The Netherlands
    Eur J Pharmacol 495:119-28. 2004
    ..Furthermore, we show that on different variables, there might be different optimal dosage combinations, which might complicate the clinical application of polytherapy...
  21. ncbi request reprint Evoked potentials to test rhythm perception theories
    Marijtje L A Jongsma
    Music, Mind, Machine Group, NICI University of Nijmegen, Nijmegen, The Netherlands
    Ann N Y Acad Sci 999:180-3. 2003
    ..We investigate this by means of EEG recordings from which evoked potentials (EPs), resulting from sensory and cognitive neural activity, are extracted...
  22. doi request reprint Neurophysiological correlates of nociceptive heterosynaptic long-term potentiation in humans
    Emanuel N van den Broeke
    The Department of Anesthesiology, Pain and Palliative Medicine, Pain and Nociception Neuroscience Research Group, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Neurophysiol 103:2107-13. 2010
    ..These findings suggest that HFS is capable of producing heterosynaptic spinal LTP that can be measured not only behaviorally but also using ERPs...
  23. ncbi request reprint Effects of the combination of valproate and ethosuximide on spike wave discharges in WAG/Rij rats
    Clementina M Van Rijn
    Department of Biological Psychology, Nijmegen Institute for Cognition and Information, University of Nijmegen, Post box 9104, 6500 HE Nijmegen, The Netherlands
    Epilepsy Res 59:181-9. 2004
    ..We studied the interaction between valproate (VPA) and ethosuximide (ESM) in diminishing the incidence of absence-like spike-wave discharges (SWDs) in the EEG of WAG/Rij rats...
  24. ncbi request reprint A four-ligand hypercube model to quantify allosteric interactions within the GABAA receptor complex
    Clementina M Van Rijn
    NICI Department of Biological Psychology, University of Nijmegen, Post box 9104, 6500 HE Nijmegen, The Netherlands
    Eur J Pharmacol 485:43-51. 2004
    ..The simultaneous binding of any two ligands enhances the affinity of the third by a factor 9. These results may contribute to the understanding of individual variability in drug responses and to the discussion about rational polytherapy...
  25. ncbi request reprint The effects of vigabatrin on type II spike wave discharges in rats
    Brigitte M Bouwman
    NICI Department of Biological Psychology, University of Nijmegen, PO Box 9104, 6500 HE, Nijmegen, The Netherlands
    Neurosci Lett 338:177-80. 2003
    ..6 Hz) as compared to saline treatment (7.5 Hz). Thus, vigabatrin alters the type II SWD morphology. These results are in agreement with predictions of Destexhe's theoretical model, modulating both GABA(A) and GABA(B) conductances...