Scott D Weatherbee

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification
    Scott D Weatherbee
    Department of Developmental Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 103:15103-7. 2006
  2. pmc IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
    Daisy Xin
    Development 144:1544-1553. 2017
  3. doi request reprint Mammalian limbs take flight
    Scott D Weatherbee
    Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA
    Dev Cell 14:149-50. 2008
  4. pmc A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling
    Scott D Weatherbee
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Hum Mol Genet 18:4565-75. 2009
  5. pmc Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling
    Kasey J Christopher
    Department of Genetics, Yale University, New Haven, CT 06520, USA
    Dev Biol 368:382-92. 2012
  6. pmc Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length
    Emily K Mis
    Department of Genetics, Yale University, New Haven, CT 06520, United States
    Dev Biol 385:67-82. 2014
  7. ncbi request reprint LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction
    Scott D Weatherbee
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10021, USA
    Development 133:4993-5000. 2006
  8. doi request reprint TMEM107 Is a Critical Regulator of Ciliary Protein Composition and Is Mutated in Orofaciodigital Syndrome
    Natalia A Shylo
    Department of Genetics, Yale University, School of Medicine, P O Box 208005, SHM I 142D, 333 Cedar Street, New Haven, CT, 06520
    Hum Mutat 37:155-9. 2016
  9. pmc Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells
    Sunjin Lee
    Department of Genetics, Yale University, New Haven, CT 06520, USA
    Dev Biol 383:201-13. 2013
  10. doi request reprint Of Mice and Snakes: A Tail of Oct4
    Natalia A Shylo
    Department of Genetics, Yale University, New Haven, CT 06520, USA
    Dev Cell 38:224-6. 2016

Collaborators

Detail Information

Publications11

  1. pmc Interdigital webbing retention in bat wings illustrates genetic changes underlying amniote limb diversification
    Scott D Weatherbee
    Department of Developmental Biology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Proc Natl Acad Sci U S A 103:15103-7. 2006
    ....
  2. pmc IFT56 regulates vertebrate developmental patterning by maintaining IFTB complex integrity and ciliary microtubule architecture.
    Daisy Xin
    Development 144:1544-1553. 2017
    ..These studies define a distinct and novel role for IFT56 in IFTB complex integrity that is crucial for cilia structure and function and, ultimately, animal development...
  3. doi request reprint Mammalian limbs take flight
    Scott D Weatherbee
    Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA
    Dev Cell 14:149-50. 2008
    ..In an attempt to understand factors influencing this diversity, Cretekos and colleagues, in a recent issue of Genes & Development, provide molecular insight into the evolution of wing morphology in bats...
  4. pmc A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and Hedgehog signaling
    Scott D Weatherbee
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10065, USA
    Hum Mol Genet 18:4565-75. 2009
    ..Thus the disruption of Hh signaling can explain many, but not all, of the defects caused by loss of Mks1...
  5. pmc Forward genetics uncovers Transmembrane protein 107 as a novel factor required for ciliogenesis and Sonic hedgehog signaling
    Kasey J Christopher
    Department of Genetics, Yale University, New Haven, CT 06520, USA
    Dev Biol 368:382-92. 2012
    ..Together, these studies identify a previously unknown regulator of ciliogenesis and provide insight into how ciliary factors affect Shh signaling and cilia biogenesis in distinct tissues...
  6. pmc Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length
    Emily K Mis
    Department of Genetics, Yale University, New Haven, CT 06520, United States
    Dev Biol 385:67-82. 2014
    ..The pug mutant serves as a novel model for mammalian dwarfism and identifies a key role for proteoglycan modification in the initiation of chondrocyte maturation. ..
  7. ncbi request reprint LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction
    Scott D Weatherbee
    Developmental Biology Program, Sloan Kettering Institute, New York, NY 10021, USA
    Development 133:4993-5000. 2006
    ..The identification of Lrp4 as a crucial factor for NMJ formation may have implications for human neuromuscular diseases such as myasthenia syndromes...
  8. doi request reprint TMEM107 Is a Critical Regulator of Ciliary Protein Composition and Is Mutated in Orofaciodigital Syndrome
    Natalia A Shylo
    Department of Genetics, Yale University, School of Medicine, P O Box 208005, SHM I 142D, 333 Cedar Street, New Haven, CT, 06520
    Hum Mutat 37:155-9. 2016
    ..These data indicate that TMEM107 plays a key, conserved role in regulating ciliary protein composition, and is a novel candidate for ciliopathies of unknown etiology. ..
  9. pmc Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells
    Sunjin Lee
    Department of Genetics, Yale University, New Haven, CT 06520, USA
    Dev Biol 383:201-13. 2013
    ....
  10. doi request reprint Of Mice and Snakes: A Tail of Oct4
    Natalia A Shylo
    Department of Genetics, Yale University, New Haven, CT 06520, USA
    Dev Cell 38:224-6. 2016
    ..Aires et al. (2016) uncover a key role for Oct4 in determining trunk length in mice. Additionally, a heterochronic shift in Oct4 expression may underlie the extreme elongation of the trunk in snakes. ..
  11. ncbi request reprint Embryonic staging system for the short-tailed fruit bat, Carollia perspicillata, a model organism for the mammalian order Chiroptera, based upon timed pregnancies in captive-bred animals
    Chris J Cretekos
    Department of Molecular Genetics, University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Dev Dyn 233:721-38. 2005
    ..This staging system provides a framework for studying Carollia embryogenesis and should prove useful as a guide for embryological studies of other bat species and for comparisons with other orders of mammals...