Paul T Jubinsky

Summary

Affiliation: Yale University
Country: USA

Publications

  1. pmc The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism
    Mary K Short
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS ONE 7:e39428. 2012
  2. doi request reprint Severe Evans syndrome with multi-system involvement is a distinct immunodeficiency disorder
    Paul T Jubinsky
    Section of Pediatric Hematology Oncology, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Pediatr Blood Cancer 52:659-61. 2009
  3. doi request reprint Design, synthesis, and biological activity of novel Magmas inhibitors
    Paul T Jubinsky
    Pediatric Hematology Oncology, Yale University Medical School, New Haven, CT 06510, United States
    Bioorg Med Chem Lett 21:3479-82. 2011
  4. ncbi request reprint Magmas expression in neoplastic human prostate
    Paul T Jubinsky
    Division of Pediatric Hematology Oncology, Albert Einstein College of Medicine, Bronx, NY, USA
    J Mol Histol 36:69-75. 2005
  5. ncbi request reprint Magmas gene structure and evolution
    Jianbin Peng
    Laboratory of Biochemistry and Molecular Genetics, Lindsley F Kimball Research Institute, New York Blood Center, New York, NY 10021, USA
    In Silico Biol 5:251-63. 2005
  6. ncbi request reprint A syndrome of holoprosencephaly, recurrent infections, and monocytosis
    Paul T Jubinsky
    Pediatric Hematology Oncology, Albert Einstein College of Medicine and Children s Hospital at Montefiore, Bronx, New York, USA
    Am J Med Genet A 140:2742-8. 2006
  7. doi request reprint Therapeutic strategies for targeting mononuclear phagocytes in cancer
    David S Dickens
    Pediatric Hematology Oncology, Helen DeVos Children s Hospital, Grand Rapids, MI, USA
    J Pediatr Hematol Oncol 31:14-7. 2009
  8. pmc Essential role of Drosophila black-pearl is mediated by its effects on mitochondrial respiration
    Soumit Roy
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    FASEB J 26:3822-33. 2012
  9. doi request reprint New roles for mononuclear phagocytes in cancer biology
    Paul T Jubinsky
    Pediatric Hematology Oncology and Developmental and Molecular Biology, Albert Einstein College of Medicine and Children s Hospital, Montefiore, Bronx, NY 10461, USA
    J Pediatr Hematol Oncol 30:584-91. 2008

Collaborators

Detail Information

Publications9

  1. pmc The yeast magmas ortholog pam16 has an essential function in fermentative growth that involves sphingolipid metabolism
    Mary K Short
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, New York, United States of America
    PLoS ONE 7:e39428. 2012
    ..Our results suggest that the pleiotropic effects caused by impaired Pam16/Magmas function are mediated in part by changes in lipid metabolism...
  2. doi request reprint Severe Evans syndrome with multi-system involvement is a distinct immunodeficiency disorder
    Paul T Jubinsky
    Section of Pediatric Hematology Oncology, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    Pediatr Blood Cancer 52:659-61. 2009
    ..These features place the patient at the most severe portion of the Evans syndrome spectrum, and suggest that this case may represent a rare, new immunodeficiency disorder...
  3. doi request reprint Design, synthesis, and biological activity of novel Magmas inhibitors
    Paul T Jubinsky
    Pediatric Hematology Oncology, Yale University Medical School, New Haven, CT 06510, United States
    Bioorg Med Chem Lett 21:3479-82. 2011
    ..Target specificity of the lead compound was established by demonstrating direct binding of the compound to Magmas and by genetic studies. Molecular modeling suggested that the inhibitor bound at the predicted site in Magmas...
  4. ncbi request reprint Magmas expression in neoplastic human prostate
    Paul T Jubinsky
    Division of Pediatric Hematology Oncology, Albert Einstein College of Medicine, Bronx, NY, USA
    J Mol Histol 36:69-75. 2005
    ..Further studies are needed to determine if Magmas expression has prognostic significance in prostate cancer...
  5. ncbi request reprint Magmas gene structure and evolution
    Jianbin Peng
    Laboratory of Biochemistry and Molecular Genetics, Lindsley F Kimball Research Institute, New York Blood Center, New York, NY 10021, USA
    In Silico Biol 5:251-63. 2005
    ..These studies demonstrate that Magmas members constitute an important family of conserved proteins having multifunctional activities, and provide a basis for future experiments...
  6. ncbi request reprint A syndrome of holoprosencephaly, recurrent infections, and monocytosis
    Paul T Jubinsky
    Pediatric Hematology Oncology, Albert Einstein College of Medicine and Children s Hospital at Montefiore, Bronx, New York, USA
    Am J Med Genet A 140:2742-8. 2006
    ..This is the first report demonstrating an association between abnormal mononuclear phagocytes and holoprosencephaly...
  7. doi request reprint Therapeutic strategies for targeting mononuclear phagocytes in cancer
    David S Dickens
    Pediatric Hematology Oncology, Helen DeVos Children s Hospital, Grand Rapids, MI, USA
    J Pediatr Hematol Oncol 31:14-7. 2009
    ..Thus therapies that regulate these cells represent an innovative approach for improving patient survival in childhood cancer...
  8. pmc Essential role of Drosophila black-pearl is mediated by its effects on mitochondrial respiration
    Soumit Roy
    Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    FASEB J 26:3822-33. 2012
    ....
  9. doi request reprint New roles for mononuclear phagocytes in cancer biology
    Paul T Jubinsky
    Pediatric Hematology Oncology and Developmental and Molecular Biology, Albert Einstein College of Medicine and Children s Hospital, Montefiore, Bronx, NY 10461, USA
    J Pediatr Hematol Oncol 30:584-91. 2008
    ..2008, in press) describes the targeting of these cells for therapeutic benefit. Incorporating these strategies into future childhood cancer protocols could be an innovative approach for improving patient outcome...