T J Dengler

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Elevated serum concentrations of cardiac troponin T in acute allograft rejection after human heart transplantation
    T J Dengler
    Department of Cardiology, University of Heidelberg, Germany
    J Am Coll Cardiol 32:405-12. 1998
  2. ncbi request reprint Differential immune response to influenza and pneumococcal vaccination in immunosuppressed patients after heart transplantation
    T J Dengler
    Department of Cardiology, Medical University Hospital, University of Heidelberg, Germany
    Transplantation 66:1340-7. 1998
  3. doi request reprint Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal
    A O Doesch
    Department of Cardiology, University of Heidelberg, Germany
    Transplant Proc 42:3694-9. 2010
  4. doi request reprint Interstitial leukocytes in right ventricular endomyocardial biopsies after heart transplantation in patients with complicated versus uneventful postoperative course
    A Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 40:947-50. 2008
  5. doi request reprint Increased incidence of acute graft rejection on calcineurin inhibitor-free immunosuppression after heart transplantation
    S Celik
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 43:1862-7. 2011
  6. ncbi request reprint Differentiated expression patterns of growth factors in routine formalin-fixed endomyocardial biopsies in the early postoperative phase after heart transplantation
    A Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 39:554-7. 2007
  7. doi request reprint Impact of apoptosis in acute rejection episodes after heart transplantation: immunohistochemical examination of right ventricular myocardial biopsies
    A Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 40:943-6. 2008
  8. ncbi request reprint Prolonged allograft survival but no tolerance induction by modulating CD28 antibody JJ319 after high-responder rat heart transplantation
    T J Dengler
    Department of Cardiology, Medical University Hospital, University of Heidelberg, Germany
    Transplantation 67:392-8. 1999
  9. ncbi request reprint The Eurotransplant High-Urgency Heart Transplantation Program: an option for patients in acute heart failure?
    A Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Thorac Cardiovasc Surg 54:414-7. 2006
  10. ncbi request reprint Extended experience and subgroup analysis using cardiac troponin T for rejection monitoring after heart transplantation
    C A Gleissner
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 34:2178-80. 2002

Collaborators

Detail Information

Publications19

  1. ncbi request reprint Elevated serum concentrations of cardiac troponin T in acute allograft rejection after human heart transplantation
    T J Dengler
    Department of Cardiology, University of Heidelberg, Germany
    J Am Coll Cardiol 32:405-12. 1998
    ..This study evaluates the concept and diagnostic efficacy of using serum troponin T for the detection of cardiac graft rejection...
  2. ncbi request reprint Differential immune response to influenza and pneumococcal vaccination in immunosuppressed patients after heart transplantation
    T J Dengler
    Department of Cardiology, Medical University Hospital, University of Heidelberg, Germany
    Transplantation 66:1340-7. 1998
    ..Due to therapeutic immunosuppression, the response to active immunizations may be reduced. The serological efficacy of pneumococcal and influenza vaccination was studied in heart transplant recipients...
  3. doi request reprint Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal
    A O Doesch
    Department of Cardiology, University of Heidelberg, Germany
    Transplant Proc 42:3694-9. 2010
    ..Markedly fewer patients with noncutaneous malignancies died after switch to a CNI-free regimen, not quite reaching statistical significance by Kaplan-Meier analysis, however...
  4. doi request reprint Interstitial leukocytes in right ventricular endomyocardial biopsies after heart transplantation in patients with complicated versus uneventful postoperative course
    A Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 40:947-50. 2008
    ..The aim of this study was to evaluate whether qualitative and quantitative analyses of various interstitial leukocytes in endomyocardial biopsies during the first 2 weeks after HTX provided early information on these complications...
  5. doi request reprint Increased incidence of acute graft rejection on calcineurin inhibitor-free immunosuppression after heart transplantation
    S Celik
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 43:1862-7. 2011
    ..Calcineurin inhibitor (CNI)-free immunosuppression is used increasingly after heart transplantation to avoid CNI toxicity, but in the absence of a randomized trial, concerns remain over an increased rejection risk...
  6. ncbi request reprint Differentiated expression patterns of growth factors in routine formalin-fixed endomyocardial biopsies in the early postoperative phase after heart transplantation
    A Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 39:554-7. 2007
    ..The aim of this study was to analyze the time course of the expression of PDGF A and B, PDGF-receptor alpha (PDGF-Ralpha) and beta, aFGF, and bFGF on formalin-fixed routine endomyocardial biopsies...
  7. doi request reprint Impact of apoptosis in acute rejection episodes after heart transplantation: immunohistochemical examination of right ventricular myocardial biopsies
    A Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 40:943-6. 2008
    ..The aim of our study was to quantify the amount and extent of apoptotic cells during acute rejection episodes after orthotopic heart transplantation...
  8. ncbi request reprint Prolonged allograft survival but no tolerance induction by modulating CD28 antibody JJ319 after high-responder rat heart transplantation
    T J Dengler
    Department of Cardiology, Medical University Hospital, University of Heidelberg, Germany
    Transplantation 67:392-8. 1999
    ..Because this approach also inhibits a potentially tolerizing signal through CTLA-4, selective blockade of CD28 ligation might induce more profound immunosuppression and transplant tolerance...
  9. ncbi request reprint The Eurotransplant High-Urgency Heart Transplantation Program: an option for patients in acute heart failure?
    A Koch
    Department of Cardiac Surgery, University of Heidelberg, Heidelberg, Germany
    Thorac Cardiovasc Surg 54:414-7. 2006
    ..But do the results of HU heart transplantation justify performing primary heart transplantation in these critically ill patients and offer an acceptable outcome?..
  10. ncbi request reprint Extended experience and subgroup analysis using cardiac troponin T for rejection monitoring after heart transplantation
    C A Gleissner
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 34:2178-80. 2002
  11. ncbi request reprint Cyclosporine withdrawal improves renal function in heart transplant patients on reduced-dose cyclosporine therapy
    C A Gleissner
    Department of Cardiology, Angiology and Pneumonology, University of Heidelberg, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    Am J Transplant 6:2750-8. 2006
    ..The results of this study warrant further confirmation in larger clinical trials that are powered to assess clinical outcomes...
  12. pmc Troponin T concentrations 72 hours after myocardial infarction as a serological estimate of infarct size
    M Licka
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Heart 87:520-4. 2002
    ....
  13. doi request reprint Increased adherence after switch from twice daily calcineurin inhibitor based treatment to once daily modified released tacrolimus in heart transplantation: a pre-experimental study
    A O Doesch
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Transplant Proc 42:4238-42. 2010
    ....
  14. ncbi request reprint Differential immunosuppressive activity of monoclonal CD2 antibodies on allograft rejection versus specific antibody production
    B Sido
    Department of Surgery, University of Heidelberg, Germany
    Eur J Immunol 28:1347-57. 1998
    ..These results demonstrate the pivotal role of CD2 signaling in mediating allogeneic immune reactions after vascularized organ transplantation while allowing specific humoral immune responses in vivo...
  15. doi request reprint Strain-encoded cardiac magnetic resonance for the evaluation of chronic allograft vasculopathy in transplant recipients
    G Korosoglou
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Am J Transplant 9:2587-96. 2009
    ..In combination with the clinical evaluation, these parameters may be effective tools for the routine surveillance of HTx-recipients...
  16. ncbi request reprint Detection of cardiac allograft rejection by real-time PCR analysis of circulating mononuclear cells
    M Schoels
    Institute of Immunology, University of Heidelberg, Heildelberg, Germany
    Clin Transplant 18:513-7. 2004
    ..We have explored the possibility of whether graft rejection could be detected by characteristic gene expression patterns in peripheral blood mononuclear cells (PBMC) of heart-transplant recipients...
  17. pmc PARP inhibition in atherosclerosis and its effects on dendritic cells, T cells and auto-antibody levels
    Christian Erbel
    Department of Cardiology, Angiology and Pneumology, Medical Clinic III, University Hospital Heidelberg, INF 410, 69120 Heidelberg, Germany
    Eur J Med Res 16:367-74. 2011
    ..Poly(ADP-ribose) polymerase-1 (PARP), a nuclear enzyme linked to DNA repair, has been shown to be involved in atherogenesis; however, the effects on dendritic cells, T cells and serum auto-antibody levels are not fully understood...
  18. ncbi request reprint Do cytokines enable risk stratification to be improved in NYHA functional class III patients? Comparison with other potential predictors of prognosis
    R Kell
    Department of Cardiology, University of Heidelberg, Heidelberg, Germany
    Eur Heart J 23:70-8. 2002
    ..The purpose of this study was to assess whether cytokines improve risk stratification in a homogeneous group of NYHA class III patients with a left ventricular ejection fraction <40%...
  19. ncbi request reprint Interstitial fibrosis in the heart: differences in extracellular matrix proteins and matrix metalloproteinases in end-stage dilated, ischaemic and valvular cardiomyopathy
    E Herpel
    Department of Pathology, University of Heidelberg, Heidelberg, Germany
    Histopathology 48:736-47. 2006
    ..To investigate whether or not there are differences in the distribution of extracellular matrix (ECM) proteins and matrix metalloproteinases (MMPs) in end-stage heart failure underlying different cardiomyopathies...