Eda Cengiz

Summary

Affiliation: Yale University
Country: USA

Publications

  1. ncbi request reprint Closer to ideal insulin action: ultra fast acting insulins
    E Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, CT, USA
    Panminerva Med 55:269-75. 2013
  2. pmc Acceleration of insulin pharmacodynamic profile by a novel insulin infusion site warming device
    Eda Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, CT 06520, USA
    Pediatr Diabetes 14:168-73. 2013
  3. pmc Analysis of a remote system to closely monitor glycemia and insulin pump delivery--is this the beginning of a wireless transformation in diabetes management?
    Eda Cengiz
    Division of Pediatric Endocrinology, Yale School of Medicine, 333 Cedar St LMP 3103, P O Box 208064, New Haven, CT 06520, USA
    J Diabetes Sci Technol 7:362-4. 2013
  4. pmc Undeniable need for ultrafast-acting insulin: the pediatric perspective
    Eda Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Diabetes Sci Technol 6:797-801. 2012
  5. pmc The alteration of aspart insulin pharmacodynamics when mixed with detemir insulin
    Eda Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 35:690-2. 2012
  6. doi request reprint A bridge to insulin pump therapy: twice-daily regimen with NPH and detemir insulins during initial treatment of youth with type 1 diabetes mellitus
    Eda Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, Connecticut 06520, USA
    Endocr Pract 17:862-6. 2011
  7. pmc A tale of two compartments: interstitial versus blood glucose monitoring
    Eda Cengiz
    Section of Pediatric Endocrinology and Yale Center for Clinical Investigation, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Diabetes Technol Ther 11:S11-6. 2009
  8. pmc New-generation diabetes management: glucose sensor-augmented insulin pump therapy
    Eda Cengiz
    Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, CT 06520, USA
    Expert Rev Med Devices 8:449-58. 2011
  9. pmc Early pharmacokinetic and pharmacodynamic effects of mixing lispro with glargine insulin: results of glucose clamp studies in youth with type 1 diabetes
    Eda Cengiz
    Division of Pediatric Endocrinology, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 33:1009-12. 2010
  10. pmc Putting brakes on insulin pump infusion to prevent hypoglycemia
    Eda Cengiz
    Yale Pediatric Endocrinology, New Haven, Connecticut 06519, USA
    J Diabetes Sci Technol 5:1142-3. 2011

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Closer to ideal insulin action: ultra fast acting insulins
    E Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, CT, USA
    Panminerva Med 55:269-75. 2013
    ..This review explains the rationale behind the undeniable need for ultra-fast acting insulins from a clinical and research perspective and summarizes ongoing and future projects to accelerate insulin action. ..
  2. pmc Acceleration of insulin pharmacodynamic profile by a novel insulin infusion site warming device
    Eda Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, CT 06520, USA
    Pediatr Diabetes 14:168-73. 2013
    ..2 unit/kg bolus dose of aspart insulin using the euglycemic clamp technique...
  3. pmc Analysis of a remote system to closely monitor glycemia and insulin pump delivery--is this the beginning of a wireless transformation in diabetes management?
    Eda Cengiz
    Division of Pediatric Endocrinology, Yale School of Medicine, 333 Cedar St LMP 3103, P O Box 208064, New Haven, CT 06520, USA
    J Diabetes Sci Technol 7:362-4. 2013
    ..Based on the results, the mySentry system met all predefined criteria for acceptability without safety issues in this small-scale, short-term study and as an example of wireless systems integration in diabetes management...
  4. pmc Undeniable need for ultrafast-acting insulin: the pediatric perspective
    Eda Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    J Diabetes Sci Technol 6:797-801. 2012
    ..Lastly, it briefly summarizes ongoing and future projects to accelerate insulin action in youth with T1DM...
  5. pmc The alteration of aspart insulin pharmacodynamics when mixed with detemir insulin
    Eda Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 35:690-2. 2012
    ..This crossover, randomized study was undertaken to determine whether mixing aspart with detemir insulin has an adverse effect on the early glucodynamic action of rapid-acting insulin analog in humans...
  6. doi request reprint A bridge to insulin pump therapy: twice-daily regimen with NPH and detemir insulins during initial treatment of youth with type 1 diabetes mellitus
    Eda Cengiz
    Division of Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, Connecticut 06520, USA
    Endocr Pract 17:862-6. 2011
    ....
  7. pmc A tale of two compartments: interstitial versus blood glucose monitoring
    Eda Cengiz
    Section of Pediatric Endocrinology and Yale Center for Clinical Investigation, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Diabetes Technol Ther 11:S11-6. 2009
    ..This article will review the differences between interstitial and blood glucose and some of the challenges in measuring interstitial glucose levels accurately...
  8. pmc New-generation diabetes management: glucose sensor-augmented insulin pump therapy
    Eda Cengiz
    Pediatric Endocrinology and Diabetes, Yale School of Medicine, New Haven, CT 06520, USA
    Expert Rev Med Devices 8:449-58. 2011
    ..This article summarizes the evolution of sensor-augmented insulin pump therapy until present day and its future applications in new-generation diabetes management...
  9. pmc Early pharmacokinetic and pharmacodynamic effects of mixing lispro with glargine insulin: results of glucose clamp studies in youth with type 1 diabetes
    Eda Cengiz
    Division of Pediatric Endocrinology, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 33:1009-12. 2010
    ....
  10. pmc Putting brakes on insulin pump infusion to prevent hypoglycemia
    Eda Cengiz
    Yale Pediatric Endocrinology, New Haven, Connecticut 06519, USA
    J Diabetes Sci Technol 5:1142-3. 2011
    ....
  11. pmc Is an automatic pump suspension feature safe for children with type 1 diabetes? An exploratory analysis with a closed-loop system
    Eda Cengiz
    Department of Pediatrics, Section of Pediatric Endocrinology, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Diabetes Technol Ther 11:207-10. 2009
    ..It has been proposed that the first step towards a closed-loop artificial pancreas might be to use a continuous glucose sensor to automatically suspend the basal insulin delivery based on projected low sensor glucose values...
  12. pmc Effect of insulin feedback on closed-loop glucose control: a crossover study
    Jessica L Ruiz
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06520 8064, USA
    J Diabetes Sci Technol 6:1123-30. 2012
    ..An insulin feedback (IFB) modification to the PID algorithm has been introduced to mitigate this risk. We examined the effect of IFB on CL BG control...
  13. doi request reprint From pumps to prevention: recent advances in the treatment of type 1 diabetes
    Jennifer Sherr
    Department of Pediatrics, Yale University School of Medicine, New Haven, CT, United States
    Drug Discov Today 14:973-81. 2009
    ..Another area of exploration is the autoimmune process that causes beta-cell destruction. Immunomodulators used for T1DM prevention and secondary intervention will be reviewed...
  14. pmc Mitigating Meal-Related Glycemic Excursions in an Insulin-Sparing Manner During Closed-Loop Insulin Delivery: The Beneficial Effects of Adjunctive Pramlintide and Liraglutide
    Jennifer L Sherr
    Yale School of Medicine, New Haven, CT
    Diabetes Care 39:1127-34. 2016
    ..Use of single-day, 30-μg/meal pramlintide lowers meal excursions during CL. We sought to further elucidate the potential benefits of adjunctive agents after 3-4 weeks of outpatient dose titration...
  15. doi request reprint Presentation of youth with type 2 diabetes in the Pediatric Diabetes Consortium
    Georgeanna J Klingensmith
    Department of Pediatrics, Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO, USA
    Pediatr Diabetes 17:266-73. 2016
    ..Type 2 diabetes (T2D) in youth is recognized as a pediatric disease, but few reports describe the characteristics during diagnosis. We describe the clinical presentation of 503 youth with T2D...
  16. pmc Effect of pramlintide on prandial glycemic excursions during closed-loop control in adolescents and young adults with type 1 diabetes
    Stuart A Weinzimer
    Department of Pediatrics, Yale University School of Medicine, New Haven, Connecticut, USA
    Diabetes Care 35:1994-9. 2012
    ..We hypothesized that delaying gastric emptying with preprandial injections of pramlintide would improve postprandial glycemia by allowing a better match between carbohydrate and insulin absorptions...
  17. pmc Severe hypoglycemia and diabetic ketoacidosis among youth with type 1 diabetes in the T1D Exchange clinic registry
    Eda Cengiz
    Department of Endocrinology, Yale University, New Haven, CT, USA
    Pediatr Diabetes 14:447-54. 2013
    ..The aim of this study was to determine the frequency of SH and DKA and identify factors related to their occurrence in the T1D Exchange pediatric and young adult cohort...
  18. pmc Clinical outcomes in youth beyond the first year of type 1 diabetes: Results of the Pediatric Diabetes Consortium (PDC) type 1 diabetes new onset (NeOn) study
    Eda Cengiz
    Department of Pediatric Endocrinology, Yale University, New Haven, Connecticut
    Pediatr Diabetes . 2016
    ..This paper describes clinical outcomes in the T1D NeOn cohort during the first 3 years postdiagnosis...
  19. pmc Pediatric diabetes consortium T1D New Onset (NeOn) study: clinical outcomes during the first year following diagnosis
    Eda Cengiz
    Department of Pediatric Endocrinology, Yale University, New Haven, CT, 06520, USA
    Pediatr Diabetes 15:287-93. 2014
    ..The objective of this report from the Pediatric Diabetes Consortium (PDC) T1D New Onset (NeOn) study was to assess the natural history and clinical outcomes in children during the first year after diagnosis of T1D...
  20. pmc Faster in and faster out: accelerating insulin absorption and action by insulin infusion site warming
    Eda Cengiz
    Division of Pediatric Endocrinology, Yale School of Medicine, New Haven, Connecticut
    Diabetes Technol Ther 16:20-5. 2014
    ..Petach-Tikvah, Israel), on insulin aspart pharmacodynamics (PD) and pharmacokinetics (PK) in adolescents with type 1 diabetes...
  21. pmc Mitigating Reductions in Glucose During Exercise on Closed-Loop Insulin Delivery: The Ex-Snacks Study
    Neha S Patel
    Yale School of Medicine, Yale Pediatric Endocrinology and Diabetes, New Haven, Connecticut
    Diabetes Technol Ther 18:794-799. 2016
    ..To assess whether snacking could be used with closed-loop (CL) insulin delivery to avoid exercise-induced reductions in plasma glucose (PG), as well as elevations in PG at the end of exercise...
  22. doi request reprint Moving toward the ideal insulin for insulin pumps
    Eda Cengiz
    A Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA
    Expert Rev Med Devices 13:57-69. 2016
    ..These technological and pharmacological advances are likely to facilitate the development of closed-loop pump systems (i.e., artificial pancreas), and improve glycemic control and quality of life for patients with diabetes. ..
  23. doi request reprint Diabetic ketoacidosis at diabetes onset: still an all too common threat in youth
    Georgeanna J Klingensmith
    Department of Pediatrics, Barbara Davis Center for Childhood Diabetes, University of Colorado School of Medicine, Aurora, CO, USA
    J Pediatr 162:330-4.e1. 2013
    ..To define the demographic and clinical characteristics of children at the onset of type 1 diabetes (T1D), with particular attention to the frequency of diabetic ketoacidosis (DKA)...
  24. doi request reprint Substance Use Disorders among Patients with Type 2 Diabetes: a Dangerous but Understudied Combination
    Kimberly N Walter
    University of Connecticut School of Medicine MC 3944, 263 Farmington Ave, Farmington, CT, 06030 3944, USA
    Curr Diab Rep 17:2. 2017
    ..It describes epidemiological data on SUDs in persons with type 2 diabetes, overviews effects of substance use on diabetes outcomes, and discusses treatments for SUDs in patients with diabetes...