Ning Zhang

Summary

Affiliation: Xenogen Corporation
Country: USA

Publications

  1. pmc Regulation of IkappaBalpha expression involves both NF-kappaB and the MAP kinase signaling pathways
    Ning Zhang
    Xenogen Corporation, Alameda, California 94501, USA
    J Inflamm (Lond) 2:10. 2005
  2. ncbi Serum amyloid A-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the effects of proteasome inhibition
    Ning Zhang
    Xenogen, Alameda, CA 94501, USA
    J Immunol 174:8125-34. 2005
  3. ncbi NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation
    Ning Zhang
    Xenogen Corporation, Alameda, California 94501, USA
    J Biol Chem 280:21400-8. 2005
  4. ncbi Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse
    Ning Zhang
    Xenogen Corporation, 860 Atlantic Ave, Alameda, CA 94501
    Blood 103:617-26. 2004
  5. ncbi An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice
    Ning Zhang
    Xenogen Corporation, Alameda, CA 94501, USA
    J Immunol 170:6307-19. 2003
  6. doi Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles
    Ning Zhang
    Caliper Life Sciences, Alameda, California, USA
    Nat Med 19:500-5. 2013
  7. doi A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging
    Ning Zhang
    Caliper Life Sciences, Alameda, CA 94501, USA
    Clin Cancer Res 15:4915-24. 2009
  8. ncbi Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain
    Ning Zhang
    Department of Neurology, Juntendo University School of Medicine, 2 1 1 Hongo, Tokyo 113 0033, Japan
    Stroke 36:2220-5. 2005
  9. ncbi [Regulatory function of nuclear factor kappa B on lymphocyte proliferation and apoptosis in bronchial asthmatic rats and effect of triptolide on the regulation]
    Ning Zhang
    Department of Respiratory Medicine, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030
    Zhongguo Zhong Xi Yi Jie He Za Zhi 24:435-8. 2004
  10. ncbi [Immunogenicity analysis of HIV vaccine based on replicating vaccinia virus Tiantan vector]
    Ying Liu
    National Center for AIDS STD Prevention and Control, China CDC, Beijing 100050, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 18:281-3. 2004

Collaborators

Detail Information

Publications65

  1. pmc Regulation of IkappaBalpha expression involves both NF-kappaB and the MAP kinase signaling pathways
    Ning Zhang
    Xenogen Corporation, Alameda, California 94501, USA
    J Inflamm (Lond) 2:10. 2005
    ..The IkappaBalpha-luc transgenic mice are useful for analyzing IkappaBalpha expression and the NF-kappaB transcriptional activity in vivo...
  2. ncbi Serum amyloid A-luciferase transgenic mice: response to sepsis, acute arthritis, and contact hypersensitivity and the effects of proteasome inhibition
    Ning Zhang
    Xenogen, Alameda, CA 94501, USA
    J Immunol 174:8125-34. 2005
    ..These results suggest that both local and systemic induction of A-SAA occur during inflammation and may contribute to the pathogenesis of chronic inflammatory diseases associated with amyloid deposition...
  3. ncbi NF-kappaB and not the MAPK signaling pathway regulates GADD45beta expression during acute inflammation
    Ning Zhang
    Xenogen Corporation, Alameda, California 94501, USA
    J Biol Chem 280:21400-8. 2005
    ..Thus, NF-kappaB signaling involves induction of GADD45beta expression, which supports the proposed role of GADD45beta in protecting cells against DNA damaged under various stress conditions...
  4. ncbi Tracking angiogenesis induced by skin wounding and contact hypersensitivity using a Vegfr2-luciferase transgenic mouse
    Ning Zhang
    Xenogen Corporation, 860 Atlantic Ave, Alameda, CA 94501
    Blood 103:617-26. 2004
    ..The Vegfr2-luc model will be valuable in monitoring the ability of drugs to affect angiogenesis in vivo...
  5. ncbi An inducible nitric oxide synthase-luciferase reporter system for in vivo testing of anti-inflammatory compounds in transgenic mice
    Ning Zhang
    Xenogen Corporation, Alameda, CA 94501, USA
    J Immunol 170:6307-19. 2003
    ..The establishment of the iNos-luc transgenic model provides a valuable tool for studying processes in which the iNOS gene is induced and for screening anti-inflammatory compounds in vivo...
  6. doi Enhanced detection of myeloperoxidase activity in deep tissues through luminescent excitation of near-infrared nanoparticles
    Ning Zhang
    Caliper Life Sciences, Alameda, California, USA
    Nat Med 19:500-5. 2013
    ..We developed a sensitive MPO detection methodology that provides a means for visualizing and quantifying oxidative stress in deep tissue. This method is amenable to rapid evaluation of anti-inflammatory agents in animal models...
  7. doi A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging
    Ning Zhang
    Caliper Life Sciences, Alameda, CA 94501, USA
    Clin Cancer Res 15:4915-24. 2009
    ..We have generated an EL1-luc/TAg transgenic mouse model that develops spontaneous and bioluminescent acinar cell carcinomas. We applied this model to noninvasively monitor tumor development and drug response...
  8. ncbi Edaravone reduces early accumulation of oxidative products and sequential inflammatory responses after transient focal ischemia in mice brain
    Ning Zhang
    Department of Neurology, Juntendo University School of Medicine, 2 1 1 Hongo, Tokyo 113 0033, Japan
    Stroke 36:2220-5. 2005
    ....
  9. ncbi [Regulatory function of nuclear factor kappa B on lymphocyte proliferation and apoptosis in bronchial asthmatic rats and effect of triptolide on the regulation]
    Ning Zhang
    Department of Respiratory Medicine, Tongji Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030
    Zhongguo Zhong Xi Yi Jie He Za Zhi 24:435-8. 2004
    ....
  10. ncbi [Immunogenicity analysis of HIV vaccine based on replicating vaccinia virus Tiantan vector]
    Ying Liu
    National Center for AIDS STD Prevention and Control, China CDC, Beijing 100050, China
    Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi 18:281-3. 2004
    ..To investigate the immunogenicity of HIV vaccine vTKgpe based on Vaccinia Virus Tiantan vector in mice and rabbits...
  11. ncbi [In vivo transfection of cis element 'decoy' against nuclear factor-kappaB binding site modulates function of T lymphocytes in asthma]
    Ning Zhang
    Department of Respiratory Medicine, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
    Zhonghua Jie He He Hu Xi Za Zhi 27:36-40. 2004
    ..To investigate the effect of nuclear factor-kappaB (NF-kappaB) decoy oligodeoxynucleotide (ODN) on proliferation, apoptosis and cytokine synthesis of T lymphocytes from asthmatic patients...
  12. ncbi Strongylocentrotus purpuratus transcription factor GATA-E binds to and represses transcription at an Otx-Goosecoid cis-regulatory element within the aboral ectoderm-specific spec2a enhancer
    Takae Kiyama
    Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, Houston, 77030, USA
    Dev Biol 280:436-47. 2005
    ..Our results show that the recently evolved proximal element contributes to the repression of spec2a in endomesoderm and oral ectoderm territories...
  13. pmc A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1
    Ning Zhang
    Laboratory of Molecular Immunoregulation, Intramural Research Support Program, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Frederick, MD 21702 1201, USA
    Proc Natl Acad Sci U S A 102:4536-41. 2005
    ....
  14. ncbi Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice
    Miki Komine-Kobayashi
    Department of Neurology, Juntendo University School of Medicine, Bunkyo ku, Tokyo, Japan
    J Cereb Blood Flow Metab 26:402-13. 2006
    ..Our study indicated that G-CSF exerts a neuroprotective effect through the direct activation of antiapoptotic pathway, and suggested that G-CSF is important for expansion of the therapeutic time window in patients with cerebral ischemia...
  15. pmc Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses
    De Yang
    Basic Research Program, SAIC Frederick, Inc, MD, USA
    J Exp Med 205:79-90. 2008
    ....
  16. ncbi Social interaction improves experimental stroke outcome
    Tara K S Craft
    Department of Psychology, The Ohio State University, Columbus, OH 43210, USA
    Stroke 36:2006-11. 2005
    ..The purpose of the present study was to determine whether affiliative social interactions before and after stroke improve ischemic outcomes as assessed through histological analysis and behavioral assays...
  17. ncbi Ege A, a novel C2 domain containing protein, is essential for GPCR-mediated gene expression in dictyostelium
    Ning Zhang
    Department of Cell Biology and Anatomy, Johns Hopkins University of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA
    Dev Biol 248:1-12. 2002
    ..We propose that Ege A is a novel cytosolic component required by early gene expression...
  18. ncbi Cilostazol protects against brain white matter damage and cognitive impairment in a rat model of chronic cerebral hypoperfusion
    Terubumi Watanabe
    Department of Neurology, Juntendo University School of Medicine, Tokyo 113 0033, Japan
    Stroke 37:1539-45. 2006
    ....
  19. ncbi Interaction of Skp1 with CENP-E at the midbody is essential for cytokinesis
    Dan Liu
    Division of Cellular Dynamics, Hefei National Laboratory and University of Science and Technology of China, Hefei, China 230027
    Biochem Biophys Res Commun 345:394-402. 2006
    ..We hypothesize that CENP-E degradation is essential for faithful mitotic exit and the proteolysis of CENP-E is mediated by SCF via a direct Skp1 link...
  20. ncbi [Establishment of a nude mouse model of orthotopically transplanted human primary malignant lymphoma of the liver]
    Qiu zhen Liu
    Department of Hepatobiliary Surgery, No 202 Hospital of PLA, Shenyang 110003, China
    Zhonghua Zhong Liu Za Zhi 28:244-7. 2006
    ..To establish a nude mouse model of orthotopically transplanted human primary malignant lymphoma of the liver, and to serve researches on pathogenesis and experimental treatment of this disease...
  21. ncbi Coexpression of erythopoietin and erythopoietin receptor in sporadic clear cell renal cell carcinoma
    Kan Gong
    Department of Urology, Peking University First Hospital, Institute of Urology, Peking University, Beijing, PR China
    Cancer Biol Ther 5:582-5. 2006
    ..Coexpression of Epo and EpoR was detected in 50 out of 54 tumors regardless of their VHL mutation status. The results suggest that coexpression of Epo and EpoR plays an important role in tumorigenesis of sporadic CCRCC...
  22. ncbi Characterization of brimonidine transport in retinal pigment epithelium
    Ning Zhang
    Department of Pharmaceutical Sciences, School of Pharmacy, University of Southern California, Los Angeles, CA, USA
    Invest Ophthalmol Vis Sci 47:287-94. 2006
    ..To investigate the involvement of carrier-mediated transport mechanisms in brimonidine transport in retinal pigment epithelium (RPE)...
  23. pmc Adenosine A2a receptors induce heterologous desensitization of chemokine receptors
    Ning Zhang
    Laboratory of Molecular Immunoregulation, Center for Cancer Research and Basic Research Program, Science Applications International Frederick, National Cancer Institute at Frederick, Frederick, MD 21702, USA
    Blood 108:38-44. 2006
    ....
  24. ncbi Blood-borne stem cells differentiate into vascular and cardiac lineages during normal development
    Ning Zhang
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
    Stem Cells Dev 15:17-28. 2006
    ..Moreover, the demonstration that blood-borne cells contribute to the development of various organs lends credence to claims that hematopoietic stem cells have utility for treating diseased or damaged tissues in the adult...
  25. ncbi Neonatal factors influence adult stroke outcome
    Tara K S Craft
    Department of Psychology, The Ohio State University, 51 Psychology Building, 1835 Neil Avenue, Columbus, OH 43210, USA
    Psychoneuroendocrinology 31:601-13. 2006
    ..Taken together, these data provide the first direct evidence that neonatal environment can substantially influence adult cerebrovascular health...
  26. ncbi Human serum paraoxonase gene polymorphisms, Q192R and L55M, are not associated with the risk of cerebral infarction in Chinese Han population
    Qing Huang
    Institute of Neurology, Xiangya Hospital of Central South University, Changsha 410008, China
    Neurol Res 28:549-54. 2006
    ..However, little is known about the role of PON1 gene polymorphism in cerebral infarction (CI). For this, we have investigated the relationship between PON1 gene polymorphisms, Q192R and L55M, and CI in Chinese Han population...
  27. pmc Cardiac expression patterns of endothelin-converting enzyme (ECE): implications for conduction system development
    David Sedmera
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Dev Dyn 237:1746-53. 2008
    ..In vivo, ET receptor blockade with bosentan delayed activation sequence maturation. These data support a role for ECE in avian cardiac conduction system differentiation and maturation...
  28. doi Neuroprotective role of angiotensin II type 2 receptor after transient focal ischemia in mice brain
    Nobukazu Miyamoto
    Department of Neurology, Juntendo University School of Medicine 2 1 1, Hongo, Bunkyo ku, Tokyo 113 8421, Japan
    Neurosci Res 61:249-56. 2008
    ..05). Our results indicated that angiotensin II type 2 receptor has antiapoptotic activity by activating the B-cell lymphoma protein-2 via the janus kinase/signal transducer and activator of transcription signaling pathway...
  29. ncbi Effect of local viral transfer of interleukin 10 gene on a rabbit arthritis model induced by interleukin 1beta
    Ning Zhang
    Department of Rheumatology and Immunology, Shengjing Hospital of China Medical University, Shenyang, Liaoning 110004, China
    Chin Med J (Engl) 121:435-8. 2008
    ..The objective of this study was to evaluate the feasibility of local recombinant retrovirus viral interleukin 10 (rRV-vIL-10) gene transfer treatment of a rabbit model of arthritis induced by IL-1beta...
  30. ncbi [Influence of varicocele on sperm chromatin structure and sperm motility]
    Jie Tang
    Reproduction Centre, The 202nd Hospital of PLA, Shenyang, Liaoning 110003, China
    Zhonghua Nan Ke Xue 13:690-2. 2007
    ..To study the influence of varicocele on sperm chromatin structure and sperm motility...
  31. ncbi FBXL5 interacts with p150Glued and regulates its ubiquitination
    Ning Zhang
    Division of Cellular Dynamics, Hefei National Laboratory for Physical Sciences and Chinese University of Science and Technology, Hefei 230027, China
    Biochem Biophys Res Commun 359:34-9. 2007
    ..Overexpression of FBXL5 promotes poly-ubiquitination of p150(Glued) and protein turnover of p150(Glued). Our findings provide a potential mechanism by which p150(Glued) protein function is regulated by SCFs...
  32. ncbi The involvement of lipid rafts in epidermal growth factor-induced chemotaxis of breast cancer cells
    Ying Liu
    Beijing National Laboratory for Molecular Sciences BNLMS and Department of Chemical Biology, College of Chemistry and Molecular Engineering, Peking University, Beijing, China
    Mol Membr Biol 24:91-101. 2007
    ..Taken together, our study indicated that integrity of lipid rafts was critical in EGF-induced chemotaxis of human breast cancer cells...
  33. ncbi Spinal cord perfusion after extensive segmental artery sacrifice: can paraplegia be prevented?
    Christian D Etz
    Department of Cardiothoracic Surgery, Mount Sinai School of Medicine, New York, NY 10029, USA
    Eur J Cardiothorac Surg 31:643-8. 2007
    ..Understanding the ability of the paraspinal anastomotic network to provide adequate spinal cord perfusion pressure (SCPP) critical for both surgical and endovascular repair of thoracoabdominal aortic aneurysms (TAAA)...
  34. ncbi Mucosal priming with PEI/DNA complex and systemic boosting with recombinant TianTan vaccinia stimulate vigorous mucosal and systemic immune responses
    Xianggang Huang
    State Key Laboratory for Infectious Diseases Prevention and Control, National Center for AIDS STD Control and Prevention NCAIDS, China CDC, Beijing, China
    Vaccine 25:2620-9. 2007
    ..These results demonstrate that the combination of intranasal priming with PEI/DNA complexes and systemic boosting with rTTV is a preferable regimen for induction of both T-cell and humoral immune responses...
  35. ncbi Development of a microscopy-based assay for protein kinase Czeta activation in human breast cancer cells
    Caijie Zhao
    Beijing National Laboratory for Molecular Sciences, Department of Chemical Biology and State Key Laboratory of Molecular Dynamic and Stable Structures, College of Chemistry, Peking University, Beijing 100871, China
    Anal Biochem 362:8-15. 2007
    ..This assay can be used in screening for inhibitors of PKCzeta activation, which is critically required for cancer cell chemotaxis...
  36. doi Ischemic preconditioning suppresses apoptosis of rabbit spinal neurocytes by inhibiting ASK1-14-3-3 dissociation
    Chengwei Yang
    The First Affiliated Hospital of Nanjing Medical University, 300 Guang Zhou Road, Jiangsu 210029, PR China
    Neurosci Lett 441:267-71. 2008
    ..These results indicate that ischemic preconditioning may have a protective affect against ASK1/14-3-3 dissociation-induced spinal cord injuries...
  37. ncbi Recombinant human granulocyte colony-stimulating factor protects against MPTP-induced dopaminergic cell death in mice by altering Bcl-2/Bax expression levels
    Xu Qing Cao
    Department of Neurology, Juntendo University School of Medicine, Tokyo, Japan
    J Neurochem 99:861-7. 2006
    ..Our findings indicate that G-CSF provides neuroprotection against MPTP-induced cell death and this effect is mediated by increasing Bcl-2 expression levels and decreasing Bax expression levels in C57BL/6 mice...
  38. doi Recruitment of endogenous stem cells for tissue repair
    Jing Zhao
    Department of Bioengineering, Clemson University, Clemson, SC 29634, USA
    Macromol Biosci 8:836-42. 2008
    ..Herein we compare the use of different sECM compositions for controlled release of HGF and concomitant recruitment of human bone marrow MSCs into the scaffold in vitro. [Figure: see text]...
  39. ncbi Stimulation of apical and basolateral VEGF-A and VEGF-C secretion by oxidative stress in polarized retinal pigment epithelial cells
    Ram Kannan
    Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90033, USA
    Mol Vis 12:1649-59. 2006
    ..To investigate whether oxidative stress modulates vascular endothelial growth factor (VEGF)-A and VEGF-C expression and polarized secretion in a human retinal pigment epithelium cell line (ARPE-19)...
  40. ncbi [Molecular identification of medicinal plants: Dendrobium chrysanthum, Dendrobium fimbriatum and their morphologically allied species by PCR-RFLP analyses]
    Ting Zhang
    Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China
    Yao Xue Xue Bao 40:728-33. 2005
    ..To establish a simple method for molecular identification of original plants of D. chrysanthum and D. fimbriatum using molecular marker rDNA ITS region...
  41. ncbi [DNA damage in lymphocytes from patients with chronic obstructive pulmonary disease]
    Jun gang Xie
    Department of Respiratory Medicine, Tongji Hospital of Tongji Medical College, Huazhong Science and Technology University, Wuhan 430030, China
    Zhonghua Nei Ke Za Zhi 44:656-8. 2005
    ..To explore the relationship of DNA damage in lymphocytes with chronic obstructive pulmonary disease (COPD)...
  42. ncbi Microorganisms in the gut of beetles: evidence from molecular cloning
    Ning Zhang
    Department of Biological Sciences, Louisiana State University, Baton Rouge, LA 70803, USA
    J Invertebr Pathol 84:226-33. 2003
    ..Examination of all gut regions of living passalids, however, failed to reveal parabasalids, and it is possible that they were parasites in the gut tissue present in low numbers...
  43. ncbi [Regulation of epidermal growth factor, thyrotropin releasing hormone and dexamethasone on the expression of fetal lung SP mRNAs in rabbits]
    Feng Ying Wang
    Department of Obstetrics and Gynecology, Southwestern Hospital, Third Military Medical University, Chongqing 400038, China
    Zhonghua Fu Chan Ke Za Zhi 38:541-4. 2003
    ..To compare the effect of epidermal growth factor (EGF), thyrotropin releasing hormone (TRH) and dexamethasone (Dex) on the expression of surfactant protein (SP)-A, SP-B and SP-C mRNA in fetal rabbit lungs...
  44. ncbi [Evaluation of radiation damage to the sperm DNA of radar operators]
    Xin Liu
    Reproduction Center, No 202 Hospital, PLA, Liaoning, Shenyang 110003, China
    Zhonghua Nan Ke Xue 9:494-6, 500. 2003
    ..To evaluate the inflicted by radar electromagnetic radiation to the sperm DNA of radar operators...
  45. ncbi Importance of extrasegmental vessels for spinal cord blood supply in a chronic porcine model
    Justus T Strauch
    Department of Cardiothoracic Surgery, Mount Sinai School of Medicine New York University, New York, NY 10029, USA
    Eur J Cardiothorac Surg 24:817-24. 2003
    ..Our purpose was to investigate the interaction of the important components of spinal cord blood supply in the pig model to enable its use for future studies of spinal cord protection...
  46. ncbi Impact of hypothermic selective cerebral perfusion compared with hypothermic cardiopulmonary bypass on cerebral hemodynamics and metabolism
    Justus T Strauch
    Department of Cardiothoracic Surgery, Mount Sinai School of Medicine New York University, One Gustave L Levy Place, P O Box 1028, New York, NY 10029, USA
    Eur J Cardiothorac Surg 24:807-16. 2003
    ..This study explored the physiology of prolonged SCP compared to hypothermic cardiopulmonary bypass (HCPB) in pigs...
  47. ncbi Selective inactivation of CCR5 and decreased infectivity of R5 HIV-1 strains mediated by opioid-induced heterologous desensitization
    Imre Szabo
    Department of Microbiology and Immunology, Temple University School of Medicine, 3400 N Broad Street, Philadelphia, PA 19140, USA
    J Leukoc Biol 74:1074-82. 2003
    ..The interference with HIV-1 uptake by heterologous desensitization of CCR5 suggests that HIV-1 interaction with this receptor is not passive but involves a signal transduction process...
  48. pmc Shikonin, a component of chinese herbal medicine, inhibits chemokine receptor function and suppresses human immunodeficiency virus type 1
    Xin Chen
    Basic Research Program, SAIC Frederick, Inc, National Cancer Institute Frederick, Frederick, Maryland 21702 1201, USA
    Antimicrob Agents Chemother 47:2810-6. 2003
    ..Therefore, shikonin, as a naturally occurring, low-molecular-weight pan-chemokine receptor inhibitor, constitutes a basis for the development of novel anti-HIV therapeutic agents...
  49. ncbi [Study on sperm quality of males living in cold area]
    Xiao Ping Ding
    Reproduction Center, 202nd Hospital of Shenyang Command, People s Liberation Army, Shenyang 110003, China
    Zhonghua Liu Xing Bing Xue Za Zhi 24:206-9; discussion 209. 2003
    ..To investigate the effects on male reproductive function working under cold area...
  50. ncbi [Studies on NaNO2-induced DNA mutation by convolution spectrometry]
    Feng Lu
    School of Pharmacy, Second Military Medical University, Shanghai 200433, China
    Yao Xue Xue Bao 37:447-9. 2002
    ..To study the sodium nitrite induced DNA mutation by convolution spectrometry (CS)...
  51. ncbi [Establishment and characteristics of orthotopically transplanted model of human primary malignant spleen lymphoma in nude mice]
    Qiuzhen Liu
    Department of PLA Hepatobiliary Surgerg, 202 Hospital, Shenyang 110003, China
    Zhonghua Zhong Liu Za Zhi 24:234-8. 2002
    ..To establish three orthotopically transplanted model of human primary malignant spleen lymphoma in the nude mice...
  52. ncbi Mild hypothermia protects the spinal cord from ischemic injury in a chronic porcine model
    Justus T Strauch
    Department of Cardiothoracic Surgery, Mount Sinai School of Medicine New York University, One Gustave L Levy Place, P O Box 1028, New York, NY 10029, USA
    Eur J Cardiothorac Surg 25:708-15. 2004
    ..This study investigated the impact of mild hypothermia during aortic cross-clamping on postoperative paraplegia in a chronic porcine model...
  53. ncbi [Role of nitric oxide--NF-kappaB signaling pathway in differentiation of human naive T lymphocytes into Th1/Th2 cells]
    Ning Zhang
    Department of Respiratory Medicine, Tongji Hospital of Tongji Medical College, Huazhong University of Sciences and Technology, Wuhan 430030, China
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 20:215-7. 2004
    ..To explore the role of nitric oxide (NO)--NF-kappaB signaling pathway in the differentiation of human naive T lymphocytes into Th1/Th2 cells...
  54. ncbi Creation of cis-regulatory elements during sea urchin evolution by co-option and optimization of a repetitive sequence adjacent to the spec2a gene
    Sandeep Dayal
    Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Dev Biol 273:436-53. 2004
    ..Our results indicated that a dynamic pattern of cis-regulatory element evolution exists for spec genes despite their conserved aboral ectoderm expression...
  55. ncbi [Role of nitric oxide-nuclear factor kappaB signal pathway in functional expression of T lymphocytes from asthmatic patients]
    Ning Zhang
    Department of Respiratory Medicine, Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
    Zhonghua Nei Ke Za Zhi 44:328-32. 2005
    ..To investigate the regulatory role of nitric oxide (NO)-nuclear factor kappaB (NF-kappaB) signal pathway in cytokine expressions, cell proliferation and apoptosis of T lymphocytes from asthmatic patients...
  56. ncbi Neutrophils promote experimental choroidal neovascularization
    Jiehao Zhou
    The Arnold and Mabel Beckman Macular Research Center, Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Mol Vis 11:414-24. 2005
    ..To investigate the role of neutrophils in the development of laser induced experimental choroidal neovascularization (CNV)...
  57. pmc Ligand-induced partitioning of human CXCR1 chemokine receptors with lipid raft microenvironments facilitates G-protein-dependent signaling
    Xuanmao Jiao
    Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, NIH, 12441 Parklawn Drive, Twinbrook II, Rockville, Maryland 20852, USA
    Mol Cell Biol 25:5752-62. 2005
    ..Our results suggest a novel mechanism by which ligand binding to CXCR1 promotes lipid raft partitioning of receptors and facilitates activation of heterotrimeric G-proteins...
  58. ncbi Target-specific catecholamine elevation induced by anticonvulsant thalamic deep brain stimulation
    Wendy C Ziai
    Division of Neurosciences Critical Care, The John s Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Epilepsia 46:878-88. 2005
    ....
  59. ncbi Structure, expression, and transcriptional regulation of the Strongylocentrotus franciscanus spec gene family encoding intracellular calcium-binding proteins
    Jeffrey T Villinski
    Department of Biochemistry and Molecular Biology, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 117, Houston 77030, USA
    Dev Genes Evol 215:410-22. 2005
    ..Our results show that the evolution of spec cis-regulatory elements is highly dynamic and that substantial alterations can occur when maintaining or grossly modifying gene expression patterns...
  60. ncbi [The expression of hypoxia inducible factor-1,2 alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau gene]
    Kan Gong
    Department of Urology, The First Hospital of Peking University, Institute of Urology, Peking University, Beijing 100034, China
    Zhonghua Wai Ke Za Zhi 43:390-3. 2005
    ..To evaluate the expression of hypoxia inducible factor (HIF)-1alpha, 2alpha in sporadic clear cell renal cell carcinoma and their relationships to the mutations of von Hippel-Lindau (VHL) gene...
  61. ncbi [Analysis of biallelic inactivation of the von Hippel-Lindau tumor suppressor gene VHL in patients of renal cell carcinoma patient]
    Ning Liu
    Department of Urology, The First Hospital, Peking University, Beijing 100034, China
    Zhonghua Wai Ke Za Zhi 43:115-7. 2005
    ..To investigate biallelic inactivation of the von Hippel-Lindau tumor suppressor gene (VHL) in patient of renal cell carcinoma (RCC) patient...
  62. ncbi The tumor-specific hyperactive forms of cyclin E are resistant to inhibition by p21 and p27
    Hannah Wingate
    Department of Experimental Radiation Oncology, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
    J Biol Chem 280:15148-57. 2005
    ..Thus, the LMW forms of cyclin E may contribute to tumorigenesis through their resistance to the inhibitory activities of p21 and p27 while sequestering these CKIs from the full-length cyclin E...
  63. ncbi Cooling to 10 degrees C and treatment with Cyclosporine A improve cerebral recovery following prolonged hypothermic circulatory arrest in a chronic porcine model
    Justus T Strauch
    Department of Cardiothoracic Surgery, Mount Sinai School of Medicine, New York University, New York, NY, USA
    Eur J Cardiothorac Surg 27:74-80. 2005
    ..This study was undertaken to assess whether cooling to 10 degrees C and/or treatment with Cyclosporine A (CsA) can reduce neurological injury during prolonged hypothermic circulatory arrest (HCA) in a chronic animal model...
  64. ncbi [Establishment and characteristics of orthotopically transplanted model of human primary malignant small intestinal lymphoma in nude mice]
    Qiu zhen Liu
    Department of Hepatobiliary Surgery, No 202 Hospital of PLA, Shenyang 110003, China
    Zhonghua Zhong Liu Za Zhi 26:461-4. 2004
    ..To establish orthotopically transplanted model of human malignant small intestinal lymphoma in nude mice and analyze their biologic characteristics...
  65. ncbi ProbID: a probabilistic algorithm to identify peptides through sequence database searching using tandem mass spectral data
    Ning Zhang
    Institute for Systems Biology, Seattle, WA 98103, USA
    Proteomics 2:1406-12. 2002
    ..The software is publicly available for use and evaluation at http://www.systemsbiology.org/research/software/proteomics/ProbID...