Sarah K Leonard

Summary

Affiliation: Wyeth Research
Country: USA

Publications

  1. doi request reprint Pharmacology of neuropeptide S in mice: therapeutic relevance to anxiety disorders
    Sarah K Leonard
    Depression and Anxiety Disorders, Discovery Neuroscience, Wyeth Research, CN8000, Princeton, NJ 08543, USA
    Psychopharmacology (Berl) 197:601-11. 2008
  2. doi request reprint Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist
    Robert H Ring
    Discovery Neuroscience, Wyeth Research, CN8000, Princeton, NJ 08543, USA
    Neuropharmacology 58:69-77. 2010
  3. ncbi request reprint Synthesis and pharmacological evaluation of substituted naphth[1,2,3-de]isoquinolines (dinapsoline analogues) as D1 and D2 dopamine receptor ligands
    Amjad M Qandil
    Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907, USA
    Bioorg Med Chem 11:1451-64. 2003

Collaborators

Detail Information

Publications3

  1. doi request reprint Pharmacology of neuropeptide S in mice: therapeutic relevance to anxiety disorders
    Sarah K Leonard
    Depression and Anxiety Disorders, Discovery Neuroscience, Wyeth Research, CN8000, Princeton, NJ 08543, USA
    Psychopharmacology (Berl) 197:601-11. 2008
    ..Neuropeptide S (NPS) and its receptor (NPSR) comprise a recently deorphaned G protein-coupled receptor system. Recent reports implicate NPS in the mediation of anxiolytic-like activity in rodents...
  2. doi request reprint Receptor and behavioral pharmacology of WAY-267464, a non-peptide oxytocin receptor agonist
    Robert H Ring
    Discovery Neuroscience, Wyeth Research, CN8000, Princeton, NJ 08543, USA
    Neuropharmacology 58:69-77. 2010
    ..A selective OTR antagonist also failed to block the effects of OT on immobility in the TST. The significance of these findings for shaping the clinical development of OTR agonists is discussed...
  3. ncbi request reprint Synthesis and pharmacological evaluation of substituted naphth[1,2,3-de]isoquinolines (dinapsoline analogues) as D1 and D2 dopamine receptor ligands
    Amjad M Qandil
    Department of Medicinal Chemistry and Molecular Pharmacology, School of Pharmacy and Pharmacal Sciences, Purdue University, West Lafayette, IN 47907, USA
    Bioorg Med Chem 11:1451-64. 2003
    ..Moreover, as rigid ligands in which small substituents can cause significant changes in selectivity, they are important tools for deriving 'differential' SARs of the dopamine receptor isoforms...