C A Holland-Staley
Affiliation: William Beaumont Hospital
- Genetic diversity and response to IFN of the NS3 protease gene from clinical strains of the hepatitis C virusC A Holland-Staley
Infectious Disease Research, Henry Ford Hospital, Detroit, Michigan, USA
Arch Virol 147:1385-406. 2002..However, 1b strains demonstrated an overall drop in the number of positions that were mutated. This study demonstrates significant differences among natural strains that may pose a problem for structure based drug development...