Affiliation: Wayne State University
- A proposed injury threshold for mild traumatic brain injuryLiying Zhang
Bioengineering Center, Wayne State University, 818 W Hancock, Detroit, Michigan 48202, USA
J Biomech Eng 126:226-36. 2004..Predictions indicated that the shear stress around the brainstem region could be an injury predictor for concussion. Statistical analyses were performed to establish the new brain injury tolerance level...
- Material characterization and computer model simulation of low density polyurethane foam used in a rodent traumatic brain injury modelLiying Zhang
Department of Biomedical Engineering, Wayne State University, 818 W Hancock Street, Detroit, MI 48201, USA
J Neurosci Methods 198:93-8. 2011..However the stress resistance of used foam is reduced to 70% of the new foam. The FU_CHANG_FOAM material model in an FE solver has been found to be adequate to simulate this rate sensitive foam...
- Injury predictors for traumatic axonal injury in a rodent head impact acceleration modelYan Li
Department of Biomedical Engineering, Wayne State University, Detroit, Michigan 48202, USA
Stapp Car Crash J 55:25-47. 2011..Receiver operator characteristic curves were used to assess the predictive power of individual and paired injury predictors. TAI tolerance curves were also proposed in this study...
- Finite element analysis of controlled cortical impact-induced cell lossHaojie Mao
Bioengineering Center, Wayne State University, Detroit, Michigan 48201, USA
J Neurotrauma 27:877-88. 2010..More research is needed to examine other regions that do not have histological data for comparison with FE model predictions before this injury mechanism and the associated injury threshold can be fully established...
- Biomechanical response of the bovine pia-arachnoid complex to tensile loading at varying strain-ratesXin Jin
Bioengineering Center, Wayne State University, Detroit, MI 48201, USA
Stapp Car Crash J 50:637-49. 2006..Results from this study revealed the pia-arachnoid complex was rate-dependent and isotropic, suggesting that the pia-arachnoid complex can provide omnidirectional support and load bearing to the adjacent brain tissue during an impact...
- Application of a finite element model of the brain to study traumatic brain injury mechanisms in the ratHaojie Mao
Bioengineering Center, Wayne State University, USA
Stapp Car Crash J 50:583-600. 2006..5 or 2.5 mm and impactor diameters of 3 or 5 mm, and at an impact direction of about 23-30 degrees laterally. Simulation results indicate that intracranial strains best correlate with experimentally obtained injuries...
- Biomechanical response of the bovine pia-arachnoid complex to normal traction loading at varying strain ratesXin Jin
Bioengineering Center, Wayne State University, 818 West Hancock, Detroit, MI 48201, USA
Stapp Car Crash J 51:115-26. 2007..Results suggest that the PAC under traction loading is stiffer than brain tissue, rate dependent, and can be characterized as linearly elastic until failure. However, no regional difference was observed...
- Impaired axoplasmic transport is the dominant injury induced by an impact acceleration injury device: an analysis of traumatic axonal injury in pyramidal tract and corpus callosum of ratsSrinivasu Kallakuri
Department of Biomedical Engineering, Wayne State University, Detroit, MI 48201, USA
Brain Res 1452:29-38. 2012..Overall, IAT appears to be the dominant injury type induced by this model and injury in Py predominates that in CC...
- Biomechanical Responses of the Brain in Swine Subject to Free-Field BlastsKe Feng
Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA
Front Neurol 7:179. 2016..A positive correlation between IOP and its corresponding biomechanical responses of the brain was also observed. These experimental data can be used to validate computer models of bTBI...
- Quantitative electroencephalography in a swine model of blast-induced brain injuryChaoyang Chen
a Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA
Brain Inj . 2016..Electroencephalography (EEG) was used to examine brain activity abnormalities earlier after blast exposure using a swine model to develop a qEEG data analysis protocol...
- Mental health symptoms among rural-to-urban migrants in China: a comparison with their urban and rural counterpartsXiaoming Li
Pediatric Prevention Research Center, Carmen and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Hutzel Building 5th Floor W534, 4707 Saint Antoine St, Detroit, MI 48201, USA
World Health Popul 11:24-38. 2009..To examine the mental health symptoms among rural-to-urban migrants in China, in comparison with representative samples of their counterparts in the rural areas from where they emigrated and urban communities to which they immigrated...
- Lifetime incidences of traumatic events and mental health among children affected by HIV/AIDS in rural ChinaXiaoming Li
Carman and Ann Adams Department of Pediatrics Prevention Research Center, Wayne State University School of Medicine, Detroit, MI 48201, USA
J Clin Child Adolesc Psychol 38:731-44. 2009..The data in the current study suggested that children affected by HIV/AIDS in China are exposed to more trauma and suffer more adjustment problems than children who do not experience HIV/AIDS in their families...
- HIV/AIDS-related sexual risk behaviors among rural residents in China: potential role of rural-to-urban migrationXiaoming Li
Prevention Research Center, Carman and Ann Adams Department of Pediatrics, School of Medicine, Wayne State University, Detroit, MI, USA
AIDS Educ Prev 19:396-407. 2007..These findings underscore the importance for HIV/AIDS education and prevention efforts targeting the migrant population in urban destinations as well as the return-migrant population in rural areas...
- Parent-adolescent sex communication in ChinaLiying Zhang
Prevention Research Center, Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, MI 48201 2196, USA
Eur J Contracept Reprod Health Care 12:138-47. 2007....
- Stigmatization experienced by rural-to-urban migrant workers in China: findings from a qualitative studyXiaoming Li
Prevention Research Center, Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan 48201 2196, USA
World Health Popul 9:29-43. 2007..The current study is a necessary first step to assess the potential impact of stigmatization on both the physical and psychological well-being of rural-to-urban migrant workers...
- Effect of social cognitive theory-based HIV education prevention program among high school students in Nanjing, ChinaXiaoming Li
Carman and Ann Adams Department of Pediatrics, Prevention Research Center, Wayne State University School of Medicine, Detroit, MI 48201, USA
Health Educ Res 26:419-31. 2011..Findings from this study support the feasibility and initial efficacy of the cultural adaptation of FOK HIV prevention program among high school students in China...
- Psychometric evaluation of the Trauma Symptoms Checklist for Children (TSCC) among children affected by HIV/AIDS in ChinaXiaoming Li
Carman and Ann Adams Department of Pediatrics Prevention Research Center, Wayne State University School of Medicine, Detroit, MI, USA
AIDS Care 21:261-70. 2009....
- Neuronal Injury and Glial Changes Are Hallmarks of Open Field Blast Exposure in Swine Frontal LobeSrinivasu Kallakuri
Department of Biomedical Engineering, Wayne State University, Detroit, Michigan, United States of America
PLoS ONE 12:e0169239. 2017..We postulate that the observed acute injury changes may progress to chronic periods after blast and may contribute to short and long-term neuronal degeneration and glial mediated inflammation...
- Correlation of mechanical impact responses and biomarker levels: A new model for biomarker evaluation in TBIYan Li
Department of Biomedical Engineering, Wayne State University, 818 W Hancock Street, Detroit, MI 48201, United States
J Neurol Sci 359:280-6. 2015..The model used in this study showed a unique ability in elucidating the relationship between biomarker levels and severity of the mechanical trauma to the brain...
- AIDS orphanages in China: reality and challengesQun Zhao
Carman and Ann Adams Department of Pediatrics, Pediatric Prevention Research Center, Wayne State University School of Medicine, Detroit, Michigan 48201 2196, USA
AIDS Patient Care STDS 23:297-303. 2009..Implications for intervention programs include continuing support from the government and nongovernmental organizations, improvements in administrative styles, and the need of incorporating psychological support within the institutions...
- Quantitative relationship between axonal injury and mechanical response in a rodent head impact acceleration modelYan Li
Department of Biomedical Engineering, Wayne State University, Detroit, Michigan 48201, USA
J Neurotrauma 28:1767-82. 2011..25-m drop in the Marmarou model may not always result in a severe injury, and TAI level is related to the linear and angular acceleration response of the rat head during impact, not necessarily the drop height...
- Life improvement, life satisfaction, and care arrangement among AIDS orphans in rural Henan, ChinaQun Zhao
Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
J Assoc Nurses AIDS Care 20:122-32. 2009..Results suggested that perceived life improvements may have resulted from access to basic needs in extremely poor communities...
- Intraoperative brain shift prediction using a 3D inhomogeneous patient-specific finite element modelJingwen Hu
Bioengineering Center, Wayne State University, Detroit, Michigan 48201, USA
J Neurosurg 106:164-9. 2007....
- Concussion in professional football: comparison with boxing head impacts--part 10David C Viano
Mild Traumatic Brain Injury Committee, National Football League, New York, New York, USA
Neurosurgery 57:1154-72; discussion 1154-72. 2005..Olympic boxers threw four different punches at an instrumented Hybrid III dummy and responses were compared with laboratory-reconstructed NFL concussions...
- Influence of impact speed on head and brain injury outcome in vulnerable road user impacts to the car hoodRikard Fredriksson
Autoliv Research, 447 83 Vårgårda, Sweden
Stapp Car Crash J 51:155-67. 2007..A 10 km/h reduction in head impact velocity, as in automatic braking, allowed 20 mm less under-hood clearance with maintained head protection of the vulnerable road user...
- Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistanceJeff Holzbeierlein
Department of Urology, Genitourinary Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
Am J Pathol 164:217-27. 2004..The specific pathways of reactivation provide opportunities for classification of resistant tumors and targeted therapies...
- Polychlorinated biphenyls contamination in women with breast cancerCorinne J Charlier
Clinical Toxicology Laboratory, Liege University Hospital, Tour II 5, CHU Sart Tilman, B 4000 Liege, Belgium
Clin Chim Acta 347:177-81. 2004..The aim of the study was to compare PCBs contamination in women suffering from breast cancer with presumably healthy women...
- Mild traumatic brain injury: neuroimaging of sports-related concussionCecilia V Mendez
Veterans Affairs Mid Atlantic Mental Illness Research, Education, and Clinical Center, Winston Salem, North Carolina 28144, USA
J Neuropsychiatry Clin Neurosci 17:297-303. 2005
- Concussion in professional football: brain responses by finite element analysis: part 9David C Viano
ProBiomechanics, LLC, Bloomfield Hills, Michigan 48304 2952, USA
Neurosurgery 57:891-916; discussion 891-916. 2005..This study compares brain responses with physician determined signs and symptoms of concussion to investigate tissue-level injury mechanisms...
- QSAR modeling of the blood-brain barrier permeability for diverse organic compoundsLiying Zhang
The Laboratory for Molecular Modeling, School of Pharmacy, University of North Carolina at Chapel Hill, CB 7360, Chapel Hill, North Carolina 27599 7360, USA
Pharm Res 25:1902-14. 2008..Development of externally predictive Quantitative Structure-Activity Relationship (QSAR) models for Blood-Brain Barrier (BBB) permeability...
- The acceptability of an injectable, once-a-month male contraceptive in ChinaLiying Zhang
National Research Institute for Population and Family Planning, Research Center of Social Medicine, Beijing 100081, China
Contraception 73:548-53. 2006....
- Modeling prostate specific antigen kinetics in patients on active surveillanceLiying Zhang
Division of Clinical Trials and Epidemiology, and Department of Radiation Oncology, and Division of Urology, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
J Urol 176:1392-7; discussion 1397-8. 2006..Prostate specific antigen doubling time was used to stratify patients into groups at low and high risk for progression. The prostate specific antigen kinetics in these 2 groups were modeled...
- Premarital sexual activities among students in a university in Beijing, ChinaLiying Zhang
Center of Social Research, National Research Institute for Family Planning, No 12, Dahuisi, Haidian District, Beijing 100081, China
Sex Transm Dis 29:212-5. 2002..Sexually transmitted diseases are becoming a serious public health problem in China. College students are recognized as one of the age groups most affected...