Hongwei Xie

Summary

Affiliation: Waters Corporation
Country: USA

Publications

  1. doi Characterization of protein impurities and site-specific modifications using peptide mapping with liquid chromatography and data independent acquisition mass spectrometry
    Hongwei Xie
    Biopharmaceutical Sciences, Waters Corporation, 34 Maple Street, Massachusetts 01757, USA
    Anal Chem 81:5699-708. 2009
  2. ncbi Characterization of a recombinant influenza vaccine candidate using complementary LC-MS methods
    Hongwei Xie
    Department of Biopharmaceutical Sciences, Waters Corporation, Milford, MA 01757, USA
    Curr Pharm Biotechnol 12:1568-79. 2011
  3. doi Characterization of glycoprotein digests with hydrophilic interaction chromatography and mass spectrometry
    Martin Gilar
    Waters Corporation, Milford, MA 01757, USA
    Anal Biochem 417:80-8. 2011
  4. doi Utility of retention prediction model for investigation of peptide separation selectivity in reversed-phase liquid chromatography: impact of concentration of trifluoroacetic acid, column temperature, gradient slope and type of stationary phase
    Martin Gilar
    Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, USA
    Anal Chem 82:265-75. 2010

Detail Information

Publications4

  1. doi Characterization of protein impurities and site-specific modifications using peptide mapping with liquid chromatography and data independent acquisition mass spectrometry
    Hongwei Xie
    Biopharmaceutical Sciences, Waters Corporation, 34 Maple Street, Massachusetts 01757, USA
    Anal Chem 81:5699-708. 2009
    ..LC-eluted peptides were successfully sequenced and covered 97% target protein sequences. Protein impurities and site-specific modifications (e.g., M-oxidation and N-deamidation) were identified and quantified...
  2. ncbi Characterization of a recombinant influenza vaccine candidate using complementary LC-MS methods
    Hongwei Xie
    Department of Biopharmaceutical Sciences, Waters Corporation, Milford, MA 01757, USA
    Curr Pharm Biotechnol 12:1568-79. 2011
    ..These methods can contribute to the monitoring of vaccine quality especially as it pertains to product comparability studies to evaluate the impact of production process changes...
  3. doi Characterization of glycoprotein digests with hydrophilic interaction chromatography and mass spectrometry
    Martin Gilar
    Waters Corporation, Milford, MA 01757, USA
    Anal Biochem 417:80-8. 2011
    ..The analysis of site-specific glycan microheterogeneity was illustrated for the CD44 fusion protein...
  4. doi Utility of retention prediction model for investigation of peptide separation selectivity in reversed-phase liquid chromatography: impact of concentration of trifluoroacetic acid, column temperature, gradient slope and type of stationary phase
    Martin Gilar
    Waters Corporation, 34 Maple Street, Milford, Massachusetts 01757, USA
    Anal Chem 82:265-75. 2010
    ..The trends suggested by calculated retention coefficients were confirmed using a set of synthetic peptides with specifically designed sequences...