Genomes and Genes
Affiliation: Washington University School of Medicine
- Chemokine GPCR signaling inhibits β-catenin during zebrafish axis formationShu Yu Wu
Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, United States of America
PLoS Biol 10:e1001403. 2012..Our study delineates a novel negative, Gsk3β-independent control mechanism of β-catenin and implicates Ccr7 as a long-hypothesized GPCR regulating vertebrate axis formation...
- Gastrulation: making and shaping germ layersLila Solnica-Krezel
Department of Developmental Biology, Washington University School of Medicine in St Louis, St Louis, Missouri 63110, USA
Annu Rev Cell Dev Biol 28:687-717. 2012..Coordination of gastrulation movements with embryonic polarity involves regulation by anteroposterior and dorsoventral patterning systems of planar polarity signaling, expression of chemokines, and cell adhesion molecules...
- Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movementsDiane S Sepich
Department of Biological Sciences, Vanderbilt University, Nashville, TN 37212, USA
Development 138:543-52. 2011..Wnt/PCP signaling influences the polarity of the microtubule cytoskeleton and, conversely, microtubules are required for the asymmetric distribution of Wnt/PCP pathway components...
- Axis formation--beta-catenin catches a WntJason R Jessen
Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee 37235, USA
Cell 120:736-7. 2005..2005). This important work not only identifies a long-sought-after dorsalizing factor but also highlights the pivotal role of extracellular cofactors in specifying the activation of either canonical or noncanonical Wnt pathways...
- Initiation of convergence and extension movements of lateral mesoderm during zebrafish gastrulationDiane S Sepich
Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235 1634, USA
Dev Dyn 234:279-92. 2005....
- Hedgehog signaling induces arterial endothelial cell formation by repressing venous cell fateCharles Williams
Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA
Dev Biol 341:196-204. 2010..Collectively, these studies suggest that arterial endothelial cells are specified and formed via repressing venous cell fate at the lateral plate mesoderm by Hh signaling during vasculogenesis...
- Embryo morphogenesis: getting down to cells and moleculesLila Solnica-Krezel
Vanderbilt University, VU Station B 351634, Nashville, TN 37235 1634, USA
Development 130:4229-33. 2003