Monica Sala-Rabanal

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. pmc Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3
    Monica Sala-Rabanal
    Department of Cell Biology and Physiology, and Center for Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Mol Pharm 10:1450-8. 2013
  2. pmc Molecular mechanisms of EAST/SeSAME syndrome mutations in Kir4.1 (KCNJ10)
    Monica Sala-Rabanal
    Department of Cell Biology and Physiology, Washington University, St Louis, Missouri 63110, USA
    J Biol Chem 285:36040-8. 2010
  3. pmc Role of a Hydrophobic Pocket in Polyamine Interactions with the Polyspecific Organic Cation Transporter OCT3
    Dan C Li
    From the Department of Cell Biology and Physiology, and the Center for the Investigation of Membrane Excitability Diseases CIMED, Washington University School of Medicine, St Louis, Missouri 63110
    J Biol Chem 290:27633-43. 2015
  4. pmc Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway Diseases
    Monica Sala-Rabanal
    Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Mediators Inflamm 2015:497387. 2015
  5. pmc Differential mechanisms of CantĂș syndrome-associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel
    Paige E Cooper
    Department of Cell Biology and Physiology, and Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, Saint Louis, MO 63110 Department of Cell Biology and Physiology, and Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, Saint Louis, MO 63110
    J Gen Physiol 146:527-40. 2015
  6. pmc Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation
    Zeynep Yurtsever
    Biochemistry Program, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 287:42138-49. 2012

Collaborators

  • Harley T Kurata
  • Misty J Eaton
  • Colin G Nichols
  • Paige E Cooper
  • Dan C Li
  • Zeynep Yurtsever
  • Sun Joo Lee
  • David T Randolph
  • Arthur G Romero
  • Michael J Holtzman
  • Richard F Heier
  • Anand C Patel
  • Suzanne M Scheaffer
  • Tom J Brett
  • Yael G Alevy
  • William T Roswit

Detail Information

Publications6

  1. pmc Polyamine transport by the polyspecific organic cation transporters OCT1, OCT2, and OCT3
    Monica Sala-Rabanal
    Department of Cell Biology and Physiology, and Center for Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Mol Pharm 10:1450-8. 2013
    ..The identification of OCTs as polyamine transport systems may contribute to further understanding of the mechanisms involved in polyamine homeostasis and aid in the design of polyamine-like OCT-targeted drugs...
  2. pmc Molecular mechanisms of EAST/SeSAME syndrome mutations in Kir4.1 (KCNJ10)
    Monica Sala-Rabanal
    Department of Cell Biology and Physiology, Washington University, St Louis, Missouri 63110, USA
    J Biol Chem 285:36040-8. 2010
    ..These results provide an explanation for the molecular defects that underlie the EAST/SeSAME syndrome...
  3. pmc Role of a Hydrophobic Pocket in Polyamine Interactions with the Polyspecific Organic Cation Transporter OCT3
    Dan C Li
    From the Department of Cell Biology and Physiology, and the Center for the Investigation of Membrane Excitability Diseases CIMED, Washington University School of Medicine, St Louis, Missouri 63110
    J Biol Chem 290:27633-43. 2015
    ..The residues identified here are key contributors to both the observed differences between OCT3 and OCT1 and to the mechanisms of substrate recognition by OCTs in general. ..
  4. pmc Novel Roles for Chloride Channels, Exchangers, and Regulators in Chronic Inflammatory Airway Diseases
    Monica Sala-Rabanal
    Department of Cell Biology and Physiology, Washington University School of Medicine, St Louis, MO 63110, USA Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, St Louis, MO 63110, USA
    Mediators Inflamm 2015:497387. 2015
    ....
  5. pmc Differential mechanisms of CantĂș syndrome-associated gain of function mutations in the ABCC9 (SUR2) subunit of the KATP channel
    Paige E Cooper
    Department of Cell Biology and Physiology, and Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, Saint Louis, MO 63110 Department of Cell Biology and Physiology, and Center for the Investigation of Membrane Excitability Diseases, Washington University School of Medicine, Saint Louis, MO 63110
    J Gen Physiol 146:527-40. 2015
    ..The results indicate that these three CS mutations all lead to overactive K(ATP) channels, but at least two mechanisms underlie the observed gain of function: decreased ATP inhibition and enhanced MgADP activation...
  6. pmc Self-cleavage of human CLCA1 protein by a novel internal metalloprotease domain controls calcium-activated chloride channel activation
    Zeynep Yurtsever
    Biochemistry Program, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Biol Chem 287:42138-49. 2012
    ..These data provide both a mechanistic basis for CLCA1 self-cleavage and a novel mechanism for regulation of chloride channel activity specific to the mucosal interface...