Affiliation: Washington University School of Medicine
- Multiplex proteomics analysis of gender-associated proteins in Brugia malayiDaojun Jiang
Department of Developmental Biology, Washington University School of Medicine, St Louis, MO 63110, USA
Int J Parasitol 42:841-50. 2012..ISH results were consistent with RNAi data for C. elegans that linked the homologues of the B. malayi proteins to gamete production and embryogenesis...
- Tissue and stage-specific distribution of Wolbachia in Brugia malayiKerstin Fischer
Infectious Diseases Division, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri, USA
PLoS Negl Trop Dis 5:e1174. 2011..Surprisingly, immunohistology and in situ hybridization techniques have not been widely used to monitor Wolbachia distribution during the filarial life cycle...
- Localization of gender-regulated gene expression in the filarial nematode Brugia malayiDaojun Jiang
Infectious Diseases Division, Department of Internal Medicine, Washington University School of Medicine, Campus Box 8051, 660 S Euclid Avenue, St Louis, MO 63110, USA
Int J Parasitol 38:503-12. 2008..Thus, ISH provides a means to independently confirm differential expression of genes identified by other methods. In addition, localization patterns provide insight regarding the function of known or novel genes in the parasite...
- Targeting protein-protein interactions for parasite controlChristina M Taylor
Department of Genetics, The Genome Center, Washington University School of Medicine, St Louis, Missouri, United States of America
PLoS ONE 6:e18381. 2011..malayi (H. sapiens parasite), which have extremely different modes of parasitism. As more genomes of pathogens are sequenced and PPI databases expanded, this methodology will become increasingly applicable...