J David Dickman

Summary

Affiliation: Washington University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Three-dimensional organization of vestibular related eye movements to rotational motion in pigeons
    J D Dickman
    Department of Research, Central Institute for the Deaf, 818 South Euclid Avenue, 63110, St Louis, MO, USA
    Vision Res 40:2831-44. 2000
  2. ncbi request reprint Morphometry of otoconia in the utricle and saccule of developing Japanese quail
    J David Dickman
    Department of Otolaryngology, Washington University, 660 South Euclid, St Louis, MO 63110, USA
    Hear Res 188:89-103. 2004
  3. ncbi request reprint Dynamics of vestibular neurons during rotational motion in alert rhesus monkeys
    J David Dickman
    Department of Otolaryngology, Washington University, 660 S Euclid, St Louis, MO 63110, USA
    Exp Brain Res 155:91-101. 2004
  4. ncbi request reprint Recovery of gaze stability during vestibular regeneration
    Asim Haque
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neurophysiol 99:853-65. 2008
  5. ncbi request reprint Regeneration of vestibular otolith afferents after ototoxic damage
    Mridha Zakir
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 26:2881-93. 2006
  6. pmc Computation of egomotion in the macaque cerebellar vermis
    Dora E Angelaki
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Cerebellum 9:174-82. 2010
  7. pmc Regeneration of vestibular horizontal semicircular canal afferents in pigeons
    Asim Haque
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurophysiol 102:1274-86. 2009
  8. ncbi request reprint Vestibular signals in primate thalamus: properties and origins
    Hui Meng
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 27:13590-602. 2007
  9. ncbi request reprint Sensory convergence solves a motion ambiguity problem
    Aasef G Shaikh
    Department of Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Curr Biol 15:1657-62. 2005
  10. ncbi request reprint Purkinje cells in posterior cerebellar vermis encode motion in an inertial reference frame
    Tatyana A Yakusheva
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 54:973-85. 2007

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Three-dimensional organization of vestibular related eye movements to rotational motion in pigeons
    J D Dickman
    Department of Research, Central Institute for the Deaf, 818 South Euclid Avenue, 63110, St Louis, MO, USA
    Vision Res 40:2831-44. 2000
    ..Frequency responses of the horizontal, vertical, and torsional slow phase components exhibited high pass filter properties with dominant time constants of approximately 3 s...
  2. ncbi request reprint Morphometry of otoconia in the utricle and saccule of developing Japanese quail
    J David Dickman
    Department of Otolaryngology, Washington University, 660 South Euclid, St Louis, MO 63110, USA
    Hear Res 188:89-103. 2004
    ..In the utricular macula, large otoconia were concentrated in the lateral regions of the epithelium. In contrast, otoconia of various sizes were distributed uniformly across the surface of the saccular macula...
  3. ncbi request reprint Dynamics of vestibular neurons during rotational motion in alert rhesus monkeys
    J David Dickman
    Department of Otolaryngology, Washington University, 660 S Euclid, St Louis, MO 63110, USA
    Exp Brain Res 155:91-101. 2004
    ....
  4. ncbi request reprint Recovery of gaze stability during vestibular regeneration
    Asim Haque
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neurophysiol 99:853-65. 2008
    ..This was true even though the head-fixed VOR response recovered normally. Recovery of gaze stability coincided well with the three stage temporal sequence of morphologic regeneration previously described by our laboratory...
  5. ncbi request reprint Regeneration of vestibular otolith afferents after ototoxic damage
    Mridha Zakir
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 26:2881-93. 2006
    ..If true, adaptive plasticity in the central neural processing of motion information would be necessitated, because it is known that many vestibular-related behaviors fully recover during regeneration...
  6. pmc Computation of egomotion in the macaque cerebellar vermis
    Dora E Angelaki
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Cerebellum 9:174-82. 2010
    ..In addition, the role of visual cues in driving and/or modifying simple and complex spike activity, a process potentially critical for long-term adaptation, constitutes another important direction for future studies...
  7. pmc Regeneration of vestibular horizontal semicircular canal afferents in pigeons
    Asim Haque
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurophysiol 102:1274-86. 2009
    ..Plasticity in central vestibular neurons processing motion information seem to be required to explain the observed morphologic and response adaptations observed in regenerating vestibular systems...
  8. ncbi request reprint Vestibular signals in primate thalamus: properties and origins
    Hui Meng
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 27:13590-602. 2007
    ..Thus, vestibular signals, which are supplied to the thalamus from both vestibular and cerebellar nuclei, are positioned for distribution to widespread cortical areas...
  9. ncbi request reprint Sensory convergence solves a motion ambiguity problem
    Aasef G Shaikh
    Department of Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Curr Biol 15:1657-62. 2005
    ..We conclude that, through integration of temporally matched, multimodal information, neurons derive the mathematical signals predicted by the equations describing the physics of the outside world...
  10. ncbi request reprint Purkinje cells in posterior cerebellar vermis encode motion in an inertial reference frame
    Tatyana A Yakusheva
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 54:973-85. 2007
    ....
  11. ncbi request reprint Vestibular gaze stabilization: different behavioral strategies for arboreal and terrestrial avians
    Asim Haque
    Deptartment of Anatomy and Neurobiology, Washington University School of Medicine, Campus Box 8108, 660 S Euclid, St Louis, MO 63110, USA
    J Neurophysiol 93:1165-73. 2005
    ..These results suggest that disparity between the stabilization strategies employed by these two birds may be attributed to differences in species-specific behavior and anatomy...
  12. pmc Behavioral state modulates the activity of brainstem sensorimotor neurons
    Kimberly L McArthur
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 31:16700-8. 2011
    ..These results demonstrate that vestibular processing in the brainstem is state dependent and lay the foundation for future studies to investigate the synaptic mechanisms responsible for these modifications...
  13. pmc Canal and otolith contributions to compensatory tilt responses in pigeons
    Kimberly L McArthur
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neurophysiol 100:1488-97. 2008
    ..These results suggest that distinct vestibular processing substrates exist for eye and head responses in pigeons and that these are likely different from the vestibular processing substrates observed in primates...
  14. ncbi request reprint Pursuit--vestibular interactions in brain stem neurons during rotation and translation
    Hui Meng
    Dept of Neurobiology, Box 8108, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    J Neurophysiol 93:3418-33. 2005
    ..These results extend previous observations for the neural processing of otolith signals within the premotor circuitry that generates the RVOR and smooth pursuit eye movements...
  15. ncbi request reprint Afferent innervation patterns of the pigeon horizontal crista ampullaris
    Asim Haque
    Department of Anatomy and Neurobiology Box 8108, Washington University School of Medicine, 660 S Euclid, St Louis, MO 63110, USA
    J Neurophysiol 96:3293-304. 2006
    ..Overall, the pigeon HCC morphology and innervation shares many common features with those of other animal classes...
  16. pmc Detection thresholds of macaque otolith afferents
    Xiong Jie Yu
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 32:8306-16. 2012
    ....
  17. pmc Posture, head stability, and orientation recovery during vestibular regeneration in pigeons
    J David Dickman
    Department of Anatomy and Neurobiology, Washington University, St Louis, MO 63110, USA
    J Assoc Res Otolaryngol 5:323-36. 2004
    ..Parallels in recovery were drawn to hair cell regeneration and afferent responsiveness, as inferred from present results and those in other investigations...
  18. ncbi request reprint Inactivation of semicircular canals causes adaptive increases in otolith-driven tilt responses
    Dora E Angelaki
    Department of Neurobiology, Washington University School of Medicine, 600 S Euclid Ave, St Louis, MO 63110, USA
    J Neurophysiol 87:1635-40. 2002
    ....
  19. ncbi request reprint Premotor neurons encode torsional eye velocity during smooth-pursuit eye movements
    Dora E Angelaki
    Department of Neurobiology, Washington University School of Medicine, and Hearing Research Department, Central Institute for the Deaf, St Louis, Missouri 63110, USA
    J Neurosci 23:2971-9. 2003
    ....
  20. pmc State-dependent sensorimotor processing: gaze and posture stability during simulated flight in birds
    Kimberly L McArthur
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neurophysiol 105:1689-700. 2011
    ..These results demonstrate that vestibular sensorimotor processing is not fixed but depends instead on the animal's behavioral state...
  21. ncbi request reprint Deficits and recovery in visuospatial memory during head motion after bilateral labyrinthine lesion
    Min Wei
    Department of Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neurophysiol 96:1676-82. 2006
    ..We conclude that intact labyrinthine signals are functionally useful for proper visuospatial memory updating during passive head and body movements...
  22. ncbi request reprint Vestibular convergence patterns in vestibular nuclei neurons of alert primates
    J David Dickman
    Department of Research, Central Institute for the Deaf, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurophysiol 88:3518-33. 2002
    ....
  23. ncbi request reprint Properties of cerebellar fastigial neurons during translation, rotation, and eye movements
    Aasef G Shaikh
    Department of Anatomy and Neurobiology, Box 8108, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neurophysiol 93:853-63. 2005
    ..These response properties suggest that the rostral FN represents a main processing center of otolith-driven information for inertial motion detection and spatial orientation...
  24. pmc Response dynamics and tilt versus translation discrimination in parietoinsular vestibular cortex
    Sheng Liu
    Department of Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Cereb Cortex 21:563-73. 2011
    ..Thus, although yaw rotation responses in PIVC appear little processed compared with other central vestibular neurons, translation and tilt responses suggest a further processing of linear acceleration signals in thalamocortical circuits...
  25. ncbi request reprint Spatial tuning and dynamics of vestibular semicircular canal afferents in rhesus monkeys
    Asim Haque
    Department of Otolaryngology, Washington University School of Medicine, 660 South Euclid, St Louis, MO 63110, USA
    Exp Brain Res 155:81-90. 2004
    ....
  26. ncbi request reprint Caspase inhibitors promote vestibular hair cell survival and function after aminoglycoside treatment in vivo
    Jonathan I Matsui
    Division of Biology and Biomedical Sciences, Washington University in St Louis, St Louis, Missouri 63110, USA
    J Neurosci 23:6111-22. 2003
    ..These findings suggest that inhibiting the activation of caspases promotes the survival of hair cells and protects against vestibular function deficits after aminoglycoside treatment...
  27. ncbi request reprint Gravity or translation: central processing of vestibular signals to detect motion or tilt
    Dora E Angelaki
    Department of Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    J Vestib Res 13:245-53. 2003
    ..These results provide the first step in further understanding multisensory convergence in normal gravity, as this task is fundamental to our appreciation of neurovestibular adaptation to altered gravity...
  28. pmc Otopetrin 1 is required for otolith formation in the zebrafish Danio rerio
    Inna Hughes
    Department of Molecular Biology and Pharmacology, Washington University Medical School, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Dev Biol 276:391-402. 2004
    ..These studies demonstrate that Otop1 has an essential and conserved role in the timing of formation and the size and shape of the developing otolith...
  29. ncbi request reprint Neurons compute internal models of the physical laws of motion
    Dora E Angelaki
    Department of Neurobiology, Washington University School of Medicine, Saint Louis, Missouri 63110, USA
    Nature 430:560-4. 2004
    ..We show that the firing rates of these populations of neurons reflect the computations necessary to construct an internal model representation of the physical equations of motion...
  30. pmc Long-term deficits in motion detection thresholds and spike count variability after unilateral vestibular lesion
    Xiong Jie Yu
    Department of Neuroscience, Baylor College of Medicine, Houston, Texas Department of Anatomy and Neurobiology, Washington University, St Louis, Missouri and
    J Neurophysiol 112:870-89. 2014
    ..These findings suggest that, after compensation, a single labyrinth is sufficient to recover motion sensitivity and normal thresholds for the otolith, but not the semicircular canal, system. ..
  31. ncbi request reprint Afferent innervation of the utricular macula in pigeons
    Xiaohong Si
    Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, Jackson, Mississippi 39211, USA
    J Neurophysiol 89:1660-77. 2003
    ..The cellular organization and innervation patterns of the utricular maculae in birds appear to represent an organ in adaptive evolution, different from that observed for amphibians or mammals...
  32. pmc Magnetoreception in an avian brain in part mediated by inner ear lagena
    Le Qing Wu
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Curr Biol 21:418-23. 2011
    ..We also found, through ablation studies, that much of the observed pathway appears to receive magnetic information from the pigeon lagena receptor organs...
  33. ncbi request reprint Separate Na,K-ATPase genes are required for otolith formation and semicircular canal development in zebrafish
    Brian Blasiole
    Department of Pharmacology, Penn State University College of Medicine, H078, Hershey, PA 17033, USA
    Dev Biol 294:148-60. 2006
    ..Our results highlight zebrafish gene knockdown-mRNA rescue as an approach that can be used to dissect the functional properties of zebrafish and mammalian Na,K-ATPase genes...