Washington University School of Medicine

Summary

Organization: Washington University School of Medicine
Country: USA

Top Publications

  1. pmc Prediction of individual brain maturity using fMRI
    Nico U F Dosenbach
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Science 329:1358-61. 2010
  2. pmc Therapy related acute myeloid leukemia in breast cancer survivors, a population-based study
    Mike G Martin
    Division of Oncology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8007, Saint Louis, MO 63110, USA
    Breast Cancer Res Treat 118:593-8. 2009
  3. pmc Tumor-derived TGF-beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer
    Tricia A Moo-Young
    Laboratory for Biologic Cancer Therapy, Department of Surgery, Washington University School of Medicine, Saint Louis, MO 63110, USA
    J Immunother 32:12-21. 2009
  4. ncbi Deformable registration of abdominal kilovoltage treatment planning CT and tomotherapy daily megavoltage CT for treatment adaptation
    Deshan Yang
    Department of Radiation Oncology, Washington University, St Louis, Missouri 63110, USA
    Med Phys 36:329-38. 2009
  5. ncbi Mechanisms of life in the seventeenth century: Borelli, Perrault, Régis
    Dennis Des Chene
    Washington University in St Louis, Campus Box 1073, St Louis, MO 63130, USA
    Stud Hist Philos Biol Biomed Sci 36:245-60. 2005
  6. doi Low-temperature studies of electron transfer to the M side of YFH reaction centers from Rhodobacter capsulatus
    Christine Kirmaier
    Department of Chemistry, Washington University, St Louis, Missouri 63130 4889, USA
    J Phys Chem B 113:1132-42. 2009
  7. doi Urinary cysteinyl leukotriene E(4) is associated with increased risk for pain and acute chest syndrome in adults with sickle cell disease
    Joshua J Field
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Hematol 84:158-60. 2009
  8. pmc Mechanism of ATP-induced local and conducted vasomotor responses in isolated rat cerebral penetrating arterioles
    Hans H Dietrich
    Department of Neurosurgery, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    J Vasc Res 46:253-64. 2009
  9. doi The 2008 National Institute of Child Health and Human Development workshop report on electronic fetal monitoring: update on definitions, interpretation, and research guidelines
    George A Macones
    Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63110, USA
    Obstet Gynecol 112:661-6. 2008
  10. ncbi How low can I go? The impact of hypoglycemia on the immature brain
    Terrie Inder
    Department of Pediatrics, St Louis Children s Hospital, Washington University, St Louis, Missouri 63110, USA
    Pediatrics 122:440-1. 2008

Detail Information

Publications62

  1. pmc Prediction of individual brain maturity using fMRI
    Nico U F Dosenbach
    Department of Neurology, Washington University School of Medicine, St Louis, MO 63110, USA
    Science 329:1358-61. 2010
    ..The greatest relative contribution to predicting individual brain maturity was made by the weakening of short-range functional connections between the adult brain's major functional networks...
  2. pmc Therapy related acute myeloid leukemia in breast cancer survivors, a population-based study
    Mike G Martin
    Division of Oncology, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8007, Saint Louis, MO 63110, USA
    Breast Cancer Res Treat 118:593-8. 2009
    ..This association maybe explained by either greater chemotherapy exposure or an interaction between therapy and genetic predisposition...
  3. pmc Tumor-derived TGF-beta mediates conversion of CD4+Foxp3+ regulatory T cells in a murine model of pancreas cancer
    Tricia A Moo-Young
    Laboratory for Biologic Cancer Therapy, Department of Surgery, Washington University School of Medicine, Saint Louis, MO 63110, USA
    J Immunother 32:12-21. 2009
    ..Collectively, these observations further support the role of TGF-beta in the induction of Treg in pancreas adenocarcinoma...
  4. ncbi Deformable registration of abdominal kilovoltage treatment planning CT and tomotherapy daily megavoltage CT for treatment adaptation
    Deshan Yang
    Department of Radiation Oncology, Washington University, St Louis, Missouri 63110, USA
    Med Phys 36:329-38. 2009
    ..Compared to rigid alignment, the proposed method improves volume matching by over 60% for the critical organs and reduces the prostate landmark registration errors by 50%...
  5. ncbi Mechanisms of life in the seventeenth century: Borelli, Perrault, Régis
    Dennis Des Chene
    Washington University in St Louis, Campus Box 1073, St Louis, MO 63130, USA
    Stud Hist Philos Biol Biomed Sci 36:245-60. 2005
    ..That he can do so while taking over, sometimes word for word, Perrault's accounts of animal motion shows that mechanistic explanation and mechanistic ontology could easily part company...
  6. doi Low-temperature studies of electron transfer to the M side of YFH reaction centers from Rhodobacter capsulatus
    Christine Kirmaier
    Department of Chemistry, Washington University, St Louis, Missouri 63130 4889, USA
    J Phys Chem B 113:1132-42. 2009
    ....
  7. doi Urinary cysteinyl leukotriene E(4) is associated with increased risk for pain and acute chest syndrome in adults with sickle cell disease
    Joshua J Field
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Am J Hematol 84:158-60. 2009
    ..1, 95% CI 1.8-27.5, P = 0.005; ACS: risk ratio 12.2, 95% CI 2.1-69.8, P = 0.005)...
  8. pmc Mechanism of ATP-induced local and conducted vasomotor responses in isolated rat cerebral penetrating arterioles
    Hans H Dietrich
    Department of Neurosurgery, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63110, USA
    J Vasc Res 46:253-64. 2009
    ..We analyzed the mechanism of ATP-induced local vasomotor responses and their effect on conducted vasomotor responses in rat cerebral penetrating arterioles...
  9. doi The 2008 National Institute of Child Health and Human Development workshop report on electronic fetal monitoring: update on definitions, interpretation, and research guidelines
    George A Macones
    Department of Obstetrics and Gynecology, Washington University in St Louis, St Louis, Missouri 63110, USA
    Obstet Gynecol 112:661-6. 2008
    ..A three-tier system for fetal heart rate tracing interpretation is also described. Lastly, prioritized topics for future research are provided...
  10. ncbi How low can I go? The impact of hypoglycemia on the immature brain
    Terrie Inder
    Department of Pediatrics, St Louis Children s Hospital, Washington University, St Louis, Missouri 63110, USA
    Pediatrics 122:440-1. 2008
  11. doi Practical applications of magnetic resonance in congenital heart disease
    Fernando R Gutierrez
    Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Boulevard, St Louis, MO 63110, USA
    Magn Reson Imaging Clin N Am 16:403-35, v. 2008
    ..An understanding of the pathophysiology and imaging characteristics of various congenital heart lesions is essential for effective implementation and accurate interpretation of the cardiac magnetic resonance examination...
  12. doi Do adherence variables predict outcome in an online program for the prevention of eating disorders?
    Jamie L Manwaring
    Department of Psychology, Washington University in St Louis, St Louis, MO 63130 4899, USA
    J Consult Clin Psychol 76:341-6. 2008
    ..Results can be used to inform future development and tailoring of prevention interventions to maximize effectiveness and facilitate dissemination...
  13. pmc Attenuated response to in vivo mechanical loading in mice with conditional osteoblast ablation of the connexin43 gene (Gja1)
    Susan K Grimston
    Division of Bone and Mineral Disease, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Bone Miner Res 23:879-86. 2008
    ..We tested this hypothesis in vivo in a model of genetic deficiency of the Cx43 gene (Gja1)...
  14. doi Is there a better way to biopsy the prostate? Prospects for a novel transrectal systematic biopsy approach
    Gerald L Andriole
    Division of Urologic Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Urology 70:22-6. 2007
    ..Its reproducibility from operator to operator suggests that it may be useful for guiding rebiopsy of specific locations within the prostate and for providing targeted focal prostate cancer therapy...
  15. doi Internal rotation and taping of the lower extremities for closed pelvic reduction
    Michael J Gardner
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Orthop Trauma 23:361-4. 2009
    ..We present a technique of internal rotation and taping of the lower extremities as an alternative or supplemental pelvic closed reduction method...
  16. pmc Transposons that clean up after themselves
    Douglas L Chalker
    Biology Department, Washington University in St, Louis, One Brookings Drive, St, Louis, MO 63130, USA
    Genome Biol 10:224. 2009
    ..A transposon in the germline genome of the ciliate Oxytricha uses its transposase to remove itself, as well as other germline-limited DNA, from the differentiating somatic genome during development...
  17. doi Selecting for extinction: nonrandom disease-associated extinction homogenizes amphibian biotas
    Kevin G Smith
    Tyson Research Center, Washington University in St Louis, 6750 Tyson Valley Rd, Eureka, MO 63025, USA
    Ecol Lett 12:1069-78. 2009
    ....
  18. doi Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli
    David A Hunstad
    Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Annu Rev Microbiol 64:203-21. 2010
    ..Advances in both in vitro and animal models of cystitis promise to provide insights into the bacterial and host transcriptional and biochemical pathways that define these pathogenic stages...
  19. pmc Combinatorial analysis for sequence and spatial motif discovery in short sequence fragments
    Ronald Jackups
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    IEEE/ACM Trans Comput Biol Bioinform 7:524-36. 2010
    ..Last, we discuss implications of motif analysis for problems involving short sequences in other families of proteins...
  20. doi When meaning matters, look but don't touch: the effects of posture on reading
    Christopher C Davoli
    Department of Psychology, Washington University, Campus Box 1125, One Brookings Drive, St Louis, MO 63130, USA
    Mem Cognit 38:555-62. 2010
    ..Readers are encouraged to be aware of this trade-off when choosing how to read a text, since both kinds of processing can be beneficial for reading...
  21. pmc Concordance of commercial data sources for neighborhood-effects studies
    Christine M Hoehner
    Department of Surgery and The Alvin J Siteman Cancer Center, School of Medicine, Washington University, St Louis, MO, USA
    J Urban Health 87:713-25. 2010
    ..6%), employee size (weighted kappa = 0.63), and sales volume (weighted kappa = 0.04). Researchers should cautiously interpret findings when using these commercial databases to yield measures of the neighborhood environment...
  22. pmc Patient responses to genetic information: studies of patients with hereditary cancer syndromes identify issues for use of genetic testing in nephrology practice
    Kimberly A Kaphingst
    Social and Behavioral Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA
    Semin Nephrol 30:203-14. 2010
    ..Examining whether and how these prior findings relate to the context of hereditary kidney disease is an important area for future research...
  23. pmc RET signaling is required for survival and normal function of nonpeptidergic nociceptors
    Judith P Golden
    Washington University Pain Center, Department of Anesthesiology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Neurosci 30:3983-94. 2010
    ..8 CKO mice. The results of this study identify the physiological role of endogenous Ret signaling in the survival and function of nociceptors...
  24. pmc In vivo lens deficiency of the R49C alphaA-crystallin mutant
    Usha P Andley
    Ophthalmology and Visual Sciences, Washington University in St Louis School of Medicine, 660 S Euclid Ave, Box 8096, St Louis, MO 63110, USA
    Exp Eye Res 90:699-702. 2010
    ..The death of fiber cells caused by this mutation may ultimately lead to loss of retinal integrity and blindness...
  25. pmc A possibility of nutriceuticals as an anti-aging intervention: activation of sirtuins by promoting mammalian NAD biosynthesis
    Shin Ichiro Imai
    Department of Developmental Biology, Washington University School of Medicine, Campus Box 8103, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Pharmacol Res 62:42-7. 2010
    ..Based on these recent findings, the possibility of sirtuin-targeted nutriceutical development will be discussed...
  26. pmc A vestibular sensation: probabilistic approaches to spatial perception
    Dora E Angelaki
    Department of Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Neuron 64:448-61. 2009
    ..This review highlights what is currently known about the role of vestibular information in these processes, the computations necessary to obtain the appropriate signals, and the benefits that have emerged thus far...
  27. pmc Molecular parameters of hyperthermia for radiosensitization
    Tej K Pandita
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63108, USA
    Crit Rev Eukaryot Gene Expr 19:235-51. 2009
    ..Thus, hyperthermia influences several molecular parameters involved in sensitizing tumor cells to radiation and can enhance the potential of targeted radiotherapy...
  28. pmc Association of area socioeconomic status and breast, cervical, and colorectal cancer screening: a systematic review
    Sandi L Pruitt
    Division of Health Behavior Research, Washington University School of Medicine, Campus Box 8504, 4444 Forest Park Avenue, Suite 6700, St Louis, MO 63108, USA
    Cancer Epidemiol Biomarkers Prev 18:2579-99. 2009
    ..A systematic review of existing studies is timely to identify conceptual and methodologic limitations and to provide a basis for future research directions and policy...
  29. doi Does treatment (nonoperative and operative) improve the two-year quality of life in patients with adult symptomatic lumbar scoliosis: a prospective multicenter evidence-based medicine study
    Keith H Bridwell
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Spine (Phila Pa 1976) 34:2171-8. 2009
    ..Prospective observational cohort study with matched and unmatched comparisons. Level II evidence...
  30. doi Gastric afferents project to the aldosterone-sensitive HSD2 neurons of the NTS
    Jung Won Shin
    Department of Anatomy and Neurobiology, Washington University School of Medicine, St Louis, MO 63110, USA
    Brain Res 1301:34-43. 2009
    ..Similarly, no afferent inputs from the liver or portal vein were found. In conclusion, HSD2 neurons receive an input mainly from the stomach and these results are considered as potential sites affecting sodium intake...
  31. ncbi Post-exercise heart rate recovery in HIV-positive individuals on highly active antiretroviral therapy. Early indicator of cardiovascular disease?
    W T Cade
    Division of Endocrinology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63108 2212, USA
    HIV Med 9:96-100. 2008
    ..Nothing is known regarding HRR in individuals infected with HIV on highly active antiretroviral therapy (HAART)...
  32. ncbi The effect of disability on the net worth of elderly people
    Martha N Ozawa
    Department of Social Policy, George Warren Brown School of Social Work, Washington University, St Louis, MO 63130, USA
    J Aging Soc Policy 19:21-38. 2007
    ....
  33. ncbi Immune regulation of viral infection and vice versa
    Herbert W Virgin
    Department of Pathology and Immunology, Center for Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Immunol Res 32:293-315. 2005
    ..Two concepts drive our approach: (1) the simultaneous analysis of immune and viral mechanisms allows novel insights, and (2) genetic tests in vivo are necessary to establish mechanisms...
  34. ncbi von Willebrand factor: two sides of a coin
    J E Sadler
    Howard Hughes Medical Institute, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Thromb Haemost 3:1702-9. 2005
    ..More research is needed to understand how VWF function is regulated, and to enable physicians to use this knowledge for the benefit of their patients...
  35. pmc Genetic epidemiology of diabetes
    M Alan Permutt
    Department of Endocrinology, Metabolism and Lipid Research, Washington University School of Medicine, St Louis, Missouri 63110 1010, USA
    J Clin Invest 115:1431-9. 2005
    ..In this review, we discuss the epidemiology of diabetes and the current understanding of the genetic bases of obesity and diabetes and provide suggestions for accelerated accumulation of clinically useful genetic information...
  36. ncbi Pulmonary embolism after ECT
    Daniel Mamah
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110 1093, USA
    J ECT 21:39-40. 2005
    ..We review the literature, discussing risk factors relevant to the pathophysiology of PE and making suggestions about the management of patients with suspicious symptoms...
  37. ncbi The value of ThinPrep and cytospin preparation in pleural effusion cytological diagnosis of mesothelioma and adenocarcinoma
    Lourdes R Ylagan
    The Lauren V Ackerman Laboratory of Surgical Pathology, Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Diagn Cytopathol 32:137-44. 2005
    ..Most cytological features evaluated, 20 of 25 (mesothelioma) and 19 of 22 (adenocarcinoma), can be seen in both preparation techniques...
  38. ncbi Abnormalities of glucose metabolism associated with atypical antipsychotic drugs
    John W Newcomer
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    J Clin Psychiatry 65:36-46. 2004
    ..The purpose of this article is to review the association between antipsychotic medications and obesity, insulin resistance, and diabetes, including the mechanisms through which these changes might be effected...
  39. ncbi Characterization and direct quantitation of cerebroside molecular species from lipid extracts by shotgun lipidomics
    Xianlin Han
    Division of Bioorganic Chemistry and Molecular Pharmacology, Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    J Lipid Res 46:163-75. 2005
    ..This method was demonstrated to have a greater than 1,000-fold linear dynamic range in the low concentration region; therefore, it should have a wide range of applications in studies of the cellular sphingolipid lipidome...
  40. ncbi Linkage disequilibrium of the brain-derived neurotrophic factor Val66Met polymorphism in children with a prepubertal and early adolescent bipolar disorder phenotype
    Barbara Geller
    Department of Psychiatry, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    Am J Psychiatry 161:1698-700. 2004
    ..Transmission of the brain-derived neurotrophic factor (BDNF) Val66 allele in children with a prepubertal and early adolescent bipolar disorder phenotype was examined...
  41. ncbi Depression and late mortality after myocardial infarction in the Enhancing Recovery in Coronary Heart Disease (ENRICHD) study
    Robert M Carney
    Department of Psychiatry, Behavioral Medicine Center, Washington University School of Medicine, St Louis, MO 63108, USA
    Psychosom Med 66:466-74. 2004
    ..It also examines the relationship between change in depression and late mortality...
  42. ncbi Hypopigmentation from imatinib mesylate (Gleevec)
    William J Grossman
    St Louis Children s Hospital, Hale Irwin Center for Hematology and Oncology, Washington University School of Medicine, 660 S Euclid Ave, St Louis, MO 63110, USA
    J Pediatr Hematol Oncol 26:214. 2004
  43. ncbi Detection of primary lung tumors in rodents by magnetic resonance imaging
    Joel R Garbow
    Department of Chemistry, Washington University, St Louis, Missouri, USA
    Cancer Res 64:2740-2. 2004
    ....
  44. ncbi The Monakow concept of diaschisis: origins and perspectives
    Stanley Finger
    Department of Psychology, Washington University, St Louis, MO 63130 4899, USA
    Arch Neurol 61:283-8. 2004
    ..Credit is given to Monakow for drawing needed attention to the dynamics of the nervous system, remote lesion effects, and recovery of function, even though the fine details or specifics of his theory have had a mixed reception...
  45. ncbi Challenges of implementing pharmacogenetics in the critical care environment
    Bradley D Freeman
    Department of Surgery, Washington University School of Medicine, 660 S Euclid Avenue, Box 8109, St Louis, Missouri 63110, USA
    Nat Rev Drug Discov 3:88-93. 2004
  46. ncbi Etiology and clinical course of abdominal pain in senior patients: a prospective, multicenter study
    Lawrence M Lewis
    Washington University, St Louis, MO 63110, USA
    J Gerontol A Biol Sci Med Sci 60:1071-6. 2005
    ..The authors describe the epidemiology and clinical course of older persons examined in emergency departments (EDs) for abdominal pain...
  47. ncbi The vitamin D prodrugs 1alpha(OH)D2, 1alpha(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells
    Alex J Brown
    Renal Division, Washington University School of Medicine, St Louis, MO 63110, USA
    Nephrol Dial Transplant 21:644-50. 2006
    ..In previous studies, 1alpha(OH)D3, a vitamin D prodrug, inhibited PTH secretion in cultured bovine parathyroid cells, but it was unclear whether 1alpha(OH)D3 itself or an active metabolite produced this inhibition...
  48. ncbi Ethical aspects of placebo groups in pain trials: lessons from psychiatry
    Elna M Nagasako
    Washington University School of Medicine, St Louis, MO 63110, USA
    Neurology 65:S59-65. 2005
    ..A review of these themes in the psychiatric research literature suggests possible strategies for analysis of this issue in the area of pain research...
  49. ncbi Morphology of breast implant fold flaw failure
    Harold J Brandon
    Department of Plastic Surgery, Washington University, One Brooking Drive, St Louis, Missouri, MO 63130 4899, USA
    J Long Term Eff Med Implants 16:441-50. 2006
    ..The microscopy analysis demonstrates that there are several different types of shell failure patterns that can be produced by a fold or wrinkle in a silicone gel breast implant...
  50. ncbi Differential methylation hybridization array of endometrial cancers reveals two novel cancer-specific methylation markers
    Israel Zighelboim
    Department of Obstetrics and Gynecology, Washington University School of Medicine and Siteman Cancer Center, St Louis, Missouri 63110, USA
    Clin Cancer Res 13:2882-9. 2007
    ..To identify novel endometrial cancer-specific methylation markers and to determine their association with clinicopathologic variables and survival outcomes...
  51. ncbi Diminished zonula occludens-1 expression in the failing human heart
    James G Laing
    Department of Internal Medicine, Washington University School of Medicine, St Louis, MO 63110, USA
    Cardiovasc Pathol 16:159-64. 2007
    ..Here, we determined whether expression of ZO-1 is altered in patients with heart failure...
  52. pmc Algebraic correction methods for computational assessment of clone overlaps in DNA fingerprint mapping
    Michael C Wendl
    Genome Sequencing Center, Washington University, St Louis, MO 63108, USA
    BMC Bioinformatics 8:127. 2007
    ..A methodology providing both improved accuracy and computational economy is required...
  53. ncbi Retinal pigment epithelial tear after intravitreal ranibizumab for subfoveal CNV secondary to AMD
    Rajendra S Apte
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO 63110, USA
    Int Ophthalmol 27:59-61. 2007
    ..To report a case of retinal pigment epithelial tear following intravitreal ranibizumab injection for subfoveal choroidal neovascularization...
  54. ncbi Complications of invasive subdural electrode monitoring at St. Louis Children's Hospital, 1994-2005
    James M Johnston
    Department of Neurosurgery and Division of Pediatric and Developmental Neurology, St Louis Children s Hospital, Washington University, St Louis, Missouri 63110, USA
    J Neurosurg 105:343-7. 2006
    ..The purpose of this study was to better define the incidence of complications associated with placement of subdural electrodes for localization of seizure foci and functional mapping in children...
  55. ncbi Drug insight: vitamin D analogs in the treatment of secondary hyperparathyroidism in patients with chronic kidney disease
    Alex J Brown
    Renal Division, Washington University School of Medicine, St Louis, MO, USA
    Nat Clin Pract Endocrinol Metab 3:134-44. 2007
    ....
  56. ncbi Cognitive change in Parkinson disease
    James E Galvin
    Department of Neurology, Alzheimer Disease Research Center, Washington University School of Medicine, St Louis, MO 63108, USA
    Alzheimer Dis Assoc Disord 20:302-10. 2006
    ..This review will examine the clinical, cognitive, neuropsychiatric features of cognitive deficits associated with PD, discuss their pathologic basis and propose avenues for future research...
  57. pmc Cigarette smoking and the risk for alcohol use disorders among adolescent drinkers
    Richard A Grucza
    Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Alcohol Clin Exp Res 30:2046-54. 2006
    ..We sought to address this issue using data from a nationally representative U.S. sample of adolescents and young adults. Specifically, we analyzed the relationship between cigarette smoking, drinking, and AUDs...
  58. ncbi Quantifying the usefulness of CT in evaluating seniors with abdominal pain
    Lawrence M Lewis
    Campus Box 8072, Division of Emergency Medicine, School of Medicine, Washington University, St Louis, MO 63110, USA
    Eur J Radiol 61:290-6. 2007
    ....
  59. ncbi One year of caloric restriction in humans: feasibility and effects on body composition and abdominal adipose tissue
    Susan B Racette
    Department of Medicine, Washington University School of Medicine, St Louis, MO 63108 2212, USA
    J Gerontol A Biol Sci Med Sci 61:943-50. 2006
    ..The objectives of this study were to determine the feasibility of prolonged CR in nonobese adults and to compare the effects of CR- and exercise-induced weight loss on body composition and abdominal adiposity...
  60. pmc A model for the pharmacological treatment of crouzon syndrome
    Chad A Perlyn
    Division of Plastic Surgery and Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Neurosurgery 59:210-5; discussion 210-5. 2006
    ..The purpose of this study was to develop a pharmacological strategy using tyrosine kinase inhibition as a novel treatment for craniosynostotic syndromes caused by constitutive FGFR activation...
  61. ncbi Pediatric lung transplantation
    Charles B Huddleston
    Washington University School of Medicine, St Louis Children s Hospital, St Louis, Missouri 63110, USA
    Semin Pediatr Surg 15:199-207. 2006
    ..The major causes of mortality late following lung transplantation are bronchiolitis obliterans, infections, and malignancy. The development of newer immunosuppressant drugs may offer hope for better results in the future...
  62. ncbi Item-specific control of automatic processes: stroop process dissociations
    Larry L Jacoby
    Department of Psychology, Washington University, St Louis, Missouri 63130 4899, USA
    Psychon Bull Rev 10:638-44. 2003
    ..The results (1) indicate that item-specific, as opposed to general, mechanisms can reduce the influence of word-reading processes on Stroop performance and (2) demonstrate the PD procedure's utility in studying Stroop phenomena..

Research Grants62

  1. Dementia of Parkinson Type: Clinicopathologic Phenotype
    James Galvin; Fiscal Year: 2004
    ..The ADRC and the Department of Neurology at Washington University School of Medicine provide the candidate with an outstanding environment to develop his skills as an independent ..
  2. THE ROLE OF SULFATIDES IN ALZHEIMER'S DISEASE
    Xianlin Han; Fiscal Year: 2007
    ..abstract_text> ..
  3. Omega-3 for Depression and Other Cardiac Risk Factors
    Robert Carney; Fiscal Year: 2007
    ..abstract_text> ..
  4. GIS and Breast Cancer Screening in Saint Louis
    Mario Schootman; Fiscal Year: 2004
    ..abstract_text> ..
  5. Depression & Mortality Following Myocardial Infarction
    Robert Carney; Fiscal Year: 2005
    ..abstract_text> ..
  6. Multilevel Model of Breast Cancer Follow-up Care
    Mario Schootman; Fiscal Year: 2005
    ..abstract_text> ..
  7. PREDICTORS OF RELAPSE TO SMOKING IN LUNG CANCER
    Mario Schootman; Fiscal Year: 2005
    ..abstract_text> ..
  8. Geography of Amputations Among African Americans
    Mario Schootman; Fiscal Year: 2005
    ..abstract_text> ..
  9. Gis, multilevel modeling and breast cancer screening
    Mario Schootman; Fiscal Year: 2002
    ..Few studies focusing on breast cancer screening have taken this approach, which we, and others feel is warranted. ..
  10. CARDIAC RISK MARKERS AND UNREMITTING DEPRESSION IN ACUTE CORONARY SYNDROME
    Robert M Carney; Fiscal Year: 2010
    ..Participants will be recruited from three St. Louis area hospitals affiliated with Washington University School of Medicine. One hundred seventy patients, who meet the DSM-IV criteria for a current major depressive ..
  11. CARDIAC RISK MARKERS AND UNREMITTING DEPRESSION IN ACUTE CORONARY SYNDROME
    Robert Carney; Fiscal Year: 2009
    ..Participants will be recruited from three St. Louis area hospitals affiliated with Washington University School of Medicine. One hundred seventy patients, who meet the DSM-IV criteria for a current major depressive ..
  12. DEPRESSION, SLEEP DISORDERS AND CORONARY HEART DISEASE
    Robert Carney; Fiscal Year: 2002
    ....
  13. Radiation Therapy in Older Breast Cancer Patients
    Mario Schootman; Fiscal Year: 2002
    ..Results will identify reasons for rural-urban differences in XRT use and may guide development of interventions that address modifiable factors associated with underutilization of XRT among rural women. ..
  14. Schizophrenia, Prefrontal Cortex, and Emotion Regulation
    Deanna M Barch; Fiscal Year: 2011
    ..This information can help us to design interventions that may help to improve social and occupational function and quality of life among individuals with schizophrenia. ..
  15. 1/5-Cognitive Neuroscience Task Reliability & Clinical Applications Consortium
    Deanna M Barch; Fiscal Year: 2010
    ..Thus, we need to improve our methods for detecting and enhancing cognitive function in schizophrenia in order to help individuals with this illness lead more productive and fulfilling lives. ..
  16. 1/5-Cognitive Neuroscience Task Reliability & Clinical Applications Consortium
    Deanna Barch; Fiscal Year: 2009
    ..Thus, we need to improve our methods for detecting and enhancing cognitive function in schizophrenia in order to help individuals with this illness lead more productive and fulfilling lives. ..
  17. 1/5-Cognitive Neuroscience Task Reliability & Clinical Applications Consortium
    Deanna M Barch; Fiscal Year: 2010
    ..Thus, we need to improve our methods for detecting and enhancing cognitive function in schizophrenia in order to help individuals with this illness lead more productive and fulfilling lives. ..
  18. Schizophrenia, Prefrontal Cortex, and Emotion Regulation
    Deanna M Barch; Fiscal Year: 2010
    ..This information can help us to design interventions that may help to improve social and occupational function and quality of life among individuals with schizophrenia. ..
  19. Schizopherenia, Prefrontal Cortex & Emotion Regulation
    Deanna Barch; Fiscal Year: 2007
    ..Such deficits are core aspects of schizophrenia that lead to functional disability, and thus a better understanding of their nature and causes is central to our attempts to better prevent and treat this illness. ..
  20. Novel noninvasive assessment of cytochrome P450 activity
    Evan Kharasch; Fiscal Year: 2009
    ..This approach may identify inter-individual variability in drug disposition and response; permit more individualized dosing, and reduces the cost of drug interaction studies. ..
  21. Novel noninvasive assessment of cytochrome P450 activity
    Evan Kharasch; Fiscal Year: 2007
    ..This approach may identify inter-individual variability in drug disposition and response; permit more individualized dosing, and reduces the cost of drug interaction studies. ..
  22. ADDICTION THERAPY: METABOLISM AND TRANSPORT-MEDIATED DRUG INTERACTIONS
    Evan D Kharasch; Fiscal Year: 2010
    ..It is also relevant to creating a better basic understanding of how drugs enter the brain and are inactivated by the body, and how therapeutic drugs affect healthy and ill individuals. ..
  23. Methadone and HIV drug interactions
    Evan D Kharasch; Fiscal Year: 2010
    ..It is also relevant to creating a better basic understanding of how drugs enter the brain and are inactivated by the body, and how therapeutic drugs affect healthy and ill individuals. ..
  24. ANESTHETIC RENAL METABOLISM--MECHANISMS AND CONSEQUENCES
    Evan Kharasch; Fiscal Year: 2002
    ..More broadly, resulting biochemical and clinical insights will be applicable to the numerous other nephrotoxic haloalkenes that are ubiquitous environmental contaminants. ..
  25. Novel noninvasive assessment of cytochrome P450 activity
    Evan Kharasch; Fiscal Year: 2002
    ..abstract_text> ..
  26. Methadone and HIV drug interactions
    Evan Kharasch; Fiscal Year: 2005
    ..abstract_text> ..
  27. Opioids in Cancer Pain & Drug Abuse: Optimizing Therapy
    Evan Kharasch; Fiscal Year: 2007
    ..Successful identification of the mechanism of HIV/AIDS drug interactions will improve the therapy of HIV/AIDS. ..