Alan J Magill

Summary

Affiliation: Walter Reed Army Medical Center
Country: USA

Publications

  1. ncbi request reprint Malaria: diagnosis and treatment of falciparum malaria in travelers during and after travel
    Alan J Magill
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910, USA
    Curr Infect Dis Rep 8:35-42. 2006
  2. ncbi request reprint The prevention of malaria
    Alan J Magill
    Division of Communicable Diseases and Immunology, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
    Prim Care 29:815-42, v-vi. 2002
  3. ncbi request reprint Cutaneous leishmaniasis in the returning traveler
    Alan J Magill
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Infect Dis Clin North Am 19:241-66, x-xi. 2005
  4. pmc Use of a rhesus Plasmodium cynomolgi model to screen for anti-hypnozoite activity of pharmaceutical substances
    Gregory A Deye
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Am J Trop Med Hyg 86:931-5. 2012
  5. doi request reprint Prolonged protection provided by a single dose of atovaquone-proguanil for the chemoprophylaxis of Plasmodium falciparum malaria in a human challenge model
    Gregory A Deye
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    Clin Infect Dis 54:232-9. 2012
  6. pmc An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines
    Peng Zhang
    Division of Experimental Therapeutics and Division of Pathology, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Am J Trop Med Hyg 88:1138-45. 2013
  7. doi request reprint Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives
    Hiroaki Shiraki
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States
    J Med Chem 54:131-42. 2011
  8. ncbi request reprint Nontraumatic deaths during U.S. Armed Forces basic training, 1977-2001
    Stephanie L Scoville
    U S Army Center for Health Promotion and Preventive Medicine, Directorate of Epidemiology and Disease Surveillance, Aberdeen Proving Ground, Maryland, USA
    Am J Prev Med 26:205-12. 2004
  9. pmc Update on rapid diagnostic testing for malaria
    Clinton K Murray
    Infectious Disease Service, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
    Clin Microbiol Rev 21:97-110. 2008
  10. ncbi request reprint Application of 3D-QSAR for identification of descriptors defining bioactivity of antimicrobial peptides
    Jayendra B Bhonsle
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Med Chem 50:6545-53. 2007

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Malaria: diagnosis and treatment of falciparum malaria in travelers during and after travel
    Alan J Magill
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, 503 Robert Grant Ave, Silver Spring, MD 20910, USA
    Curr Infect Dis Rep 8:35-42. 2006
    ..The availability of atovaquone-proguanil, a safe and well tolerated oral drug, should prompt a reconsideration of current treatment recommendations that discourage empiric treatment on clinical suspicion alone...
  2. ncbi request reprint The prevention of malaria
    Alan J Magill
    Division of Communicable Diseases and Immunology, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910, USA
    Prim Care 29:815-42, v-vi. 2002
    ..In this article, the author focuses on practical uses of currently available prevention tools...
  3. ncbi request reprint Cutaneous leishmaniasis in the returning traveler
    Alan J Magill
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Infect Dis Clin North Am 19:241-66, x-xi. 2005
    ..All three of these syndromes have been documented in returning travelers. This article focuses on cutaneous leishmaniasis with some comment on mucosal leishmaniasis...
  4. pmc Use of a rhesus Plasmodium cynomolgi model to screen for anti-hypnozoite activity of pharmaceutical substances
    Gregory A Deye
    Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    Am J Trop Med Hyg 86:931-5. 2012
    ..The rhesus macaque-P. cynomolgi model remains a useful tool for screening drugs with anti-hypnozoite activity. Tinidazole and pyrazinamide require further investigation as agents to enable dose reduction of primaquine...
  5. doi request reprint Prolonged protection provided by a single dose of atovaquone-proguanil for the chemoprophylaxis of Plasmodium falciparum malaria in a human challenge model
    Gregory A Deye
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, USA
    Clin Infect Dis 54:232-9. 2012
    ..We conducted a randomized, placebo-controlled, double-blind trial to establish the efficacy of atovaquone-proguanil to prevent malaria with the goal of simulating weekly dosing in a human Plasmodium falciparum challenge model...
  6. pmc An in vivo drug screening model using glucose-6-phosphate dehydrogenase deficient mice to predict the hemolytic toxicity of 8-aminoquinolines
    Peng Zhang
    Division of Experimental Therapeutics and Division of Pathology, Walter Reed Army Institute of Research, Silver Spring, MD, USA
    Am J Trop Med Hyg 88:1138-45. 2013
    ..These results suggest that this model is suitable for evaluation of selected 8-AQ type candidate antimalarial drugs for their hemolytic potential...
  7. doi request reprint Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives
    Hiroaki Shiraki
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, Maryland 20910, United States
    J Med Chem 54:131-42. 2011
    ..The new compounds showed no significant causal prophylactic activity in mice infected with Plasmodium berghei sporozoites, but are substantially less toxic than 2 and 3 in mouse tests...
  8. ncbi request reprint Nontraumatic deaths during U.S. Armed Forces basic training, 1977-2001
    Stephanie L Scoville
    U S Army Center for Health Promotion and Preventive Medicine, Directorate of Epidemiology and Disease Surveillance, Aberdeen Proving Ground, Maryland, USA
    Am J Prev Med 26:205-12. 2004
    ..A Recruit Mortality Registry, linked to the Department of Defense Medical Mortality Registry, was created to provide comprehensive medical surveillance data for deaths occurring during enlisted basic military training...
  9. pmc Update on rapid diagnostic testing for malaria
    Clinton K Murray
    Infectious Disease Service, Brooke Army Medical Center, 3851 Roger Brooke Drive, Fort Sam Houston, TX 78234, USA
    Clin Microbiol Rev 21:97-110. 2008
    ..This review highlights RDTs, including challenges in assessing their performance, internationally available RDTs, their effectiveness in various health care settings, and the selection of RDTs for different health care systems...
  10. ncbi request reprint Application of 3D-QSAR for identification of descriptors defining bioactivity of antimicrobial peptides
    Jayendra B Bhonsle
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Med Chem 50:6545-53. 2007
    ..These results support the hypothesis that, for any particular AMP, organism selectivity and potency are controlled by the chemical composition of the target cell membrane...
  11. pmc Review: Malaria chemoprophylaxis for travelers to Latin America
    Laura C Steinhardt
    Malaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Prevention and Control, Atlanta, Georgia 30333, USA
    Am J Trop Med Hyg 85:1015-24. 2011
    ..Primaquine should be strongly considered for nonpregnant, G6PD-nondeficient patients traveling to vivax-endemic areas of Latin America, and it has the added benefit of being the only drug to protect against malaria relapses...
  12. pmc Plasmodium falciparum infection during suppressive prophylaxis with mefloquine does not induce an antibody response to merozoite surface protein-1(42)
    James E Moon
    Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 7500, USA
    Am J Trop Med Hyg 84:825-9. 2011
    ..We conclude that malaria infection during suppressive prophylaxis does not induce antibody response to the blood-stage antigen MSP1(42) in a malaria-naïve study population...
  13. ncbi request reprint Malaria causal prophylactic activity of imidazolidinedione derivatives
    Jian Guan
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA
    J Med Chem 50:6226-31. 2007
    ..The results suggest the metabolites, s-triazine derivatives 7, may be the active species of the new carboxamides 5a-c and 6a-c prepared in this study...
  14. ncbi request reprint Anemia in parasite- and recombinant protein-immunized aotus monkeys infected with Plasmodium falciparum
    Trevor R Jones
    Malaria Program, Naval Medical Research Center, Silver Spring, Maryland 20910, USA
    Am J Trop Med Hyg 66:672-9. 2002
    ..Partial immunity-whether induced by repeated immunization with whole parasites or with vaccine-seems important to the development of anemia...
  15. ncbi request reprint Phase I dose escalation safety and immunogenicity trial of Plasmodium falciparum apical membrane protein (AMA-1) FMP2.1, adjuvanted with AS02A, in malaria-naïve adults at the Walter Reed Army Institute of Research
    Mark E Polhemus
    Walter Reed Army Institute of Research, Silver Spring, MD, United States
    Vaccine 25:4203-12. 2007
    ..1/AS02A in an endemic population in the Republic of Mali...
  16. ncbi request reprint De novo design of selective antibiotic peptides by incorporation of unnatural amino acids
    Rickey P Hicks
    Division of Experimental Therapeutics, Walter Reed Army Institute of Research 503 Robert Grant Avenue, Silver Spring, Maryland 20910, USA
    J Med Chem 50:3026-36. 2007
    ..The methods and results of this investigation are described below...
  17. ncbi request reprint Drug-free holidays: pre-travel versus during travel malaria chemoprophylaxis
    G Dennis Shanks
    Am J Trop Med Hyg 77:1-2. 2007
    ..Treatment regimens of antimalarial drugs taken prior to travel could protect persons for up to one month of exposure. We urge additional testing of pre-travel malaria chemoprophylaxis regimens...
  18. ncbi request reprint Epidemiology and spatial analysis of malaria in the Northern Peruvian Amazon
    Christian T Bautista
    US Naval Medical Research Center Detachment, Lima, Peru
    Am J Trop Med Hyg 75:1216-22. 2006
    ..Modest targeted control efforts directed at identified high-risk areas may have significant impact on malaria transmission in this region...
  19. pmc Devices for rapid diagnosis of Malaria: evaluation of prototype assays that detect Plasmodium falciparum histidine-rich protein 2 and a Plasmodium vivax-specific antigen
    J Russ Forney
    United States Military Academy, West Point, New York, USA
    J Clin Microbiol 41:2358-66. 2003
    ..vivax were 0.8907 and 0.8522, respectively. These findings indicate that assays for rapid diagnosis have the potential to enhance diagnostic capabilities in those instances in which skilled microscopy is not readily available...
  20. ncbi request reprint Traveling with infants and children. Part IV: insect avoidance and malaria prevention
    William M Stauffer
    Regions Hospital Center for International Health and International Travel Clinic, 640 Jackson Street, St Paul, Minnesota 55101, USA
    J Travel Med 10:225-40. 2003
  21. ncbi request reprint Rapid diagnostic devices for malaria: field evaluation of a new prototype immunochromatographic assay for the detection of Plasmodium falciparum and non-falciparum Plasmodium
    Chansuda Wongsrichanalai
    Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Am J Trop Med Hyg 69:26-30. 2003
    ..malariae; thus, specificity for non-falciparum Plasmodium was 100%. These results suggest improved performance over NOW ICT predecessors...
  22. ncbi request reprint Polymorphism of the Plasmodium falciparum multidrug resistance and chloroquine resistance transporter genes and in vitro susceptibility to aminoquinolines in isolates from the Peruvian Amazon
    Maria Cecilia Huaman
    Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan
    Am J Trop Med Hyg 70:461-6. 2004
    ..The pfcrt mutation K76T, associated with CQ resistance, was identified in all the isolates tested. Sequence analysis of codons 72-76 in the pfcrt gene showed the haplotypes SVMNT and CVMNT...
  23. ncbi request reprint Efficacy of sulfadoxine-pyrimethamine and mefloquine for the treatment of uncomplicated Plasmodium falciparum malaria in the Amazon basin of Peru
    Alan J Magill
    Naval Medical Research Center Detachment Lima, Peru
    Rev Soc Bras Med Trop 37:279-81. 2004
    ....
  24. pmc White blood cell counts and malaria
    F Ellis McKenzie
    Fogarty International Center, National Institutes of Health, Bethesda, Maryland 20892, USA
    J Infect Dis 192:323-30. 2005
    ..For instance, in the present study, use of this conventional approach would have overestimated average asexual parasite densities in the P. falciparum-infected patients in Thailand by nearly one-third...
  25. pmc Sources of variability in determining malaria parasite density by microscopy
    Wendy Prudhomme O'Meara
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
    Am J Trop Med Hyg 73:593-8. 2005
    ..We discuss the implications of this analysis for field studies and clinical trials...
  26. pmc Fever in patients with mixed-species malaria
    F Ellis McKenzie
    Fogarty International Center, National Institutes of Health, Bethesda, MD 20892, USA
    Clin Infect Dis 42:1713-8. 2006
    ..Clinical symptoms of mixed-species malaria infections have been variously reported as both less severe and more severe than those of single-species infections...
  27. ncbi request reprint Visceral leishmaniasis: clinical observations in 4 US army soldiers deployed to Afghanistan or Iraq, 2002-2004
    Otha Myles
    Arch Intern Med 167:1899-901. 2007
  28. ncbi request reprint Anemia and antibodies to the 19-kDa fragment of MSP1 during Plasmodium falciparum infection in Aotus monkeys
    Alfonso S Gozalo
    US Naval Medical Research Center Detachment, Lima, Peru
    Comp Med 57:396-401. 2007
    ..The results of this study suggest that antibody to the 19-kDa carboxy-terminal fragment of MSP1 plays a role in preventing the development of anemia, an important complication often associated with malaria...
  29. ncbi request reprint Primaquine: report from CDC expert meeting on malaria chemoprophylaxis I
    David R Hill
    National Travel Health Network and Centre, London School of Hygiene and Tropical Medicine Mortimer Market Centre, London, England
    Am J Trop Med Hyg 75:402-15. 2006
    ..The adult dose for primary prophylaxis is 30 mg daily begun 1 day before travel and continued for 7 days after return. This review will examine the evidence for these recommendations...
  30. ncbi request reprint Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum
    John C Wootton
    Computational Biology Branch, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894 6075, USA
    Nature 418:320-3. 2002
    ..The presence of linkage disequilibrium provides a basis for mapping genes under drug selection in P. falciparum...