David R Johnson
Affiliation: Walter Reed Army Medical Center
- In vitro gene regulatory networks predict in vivo function of liverYouping Deng
Rush University Medical Center, Chicago, IL 60612, USA
BMC Syst Biol 4:153. 2010..However, the degree to which we can extend in vitro results to in vivo activity and possible mechanisms of action remains to be fully addressed...
- Potential for occupational exposure to engineered carbon-based nanomaterials in environmental laboratory studiesDavid R Johnson
U S Army Engineer Research and Development Center, Environmental Laboratory, Vicksburg, Mississippi 39180, USA
Environ Health Perspect 118:49-54. 2010..g., presence of natural organic matter (NOM)]...
- Tungsten effects on phosphate-dependent biochemical pathways are species and liver cell line dependentDavid R Johnson
Environmental Laboratory, US Army Engineer Research and Development Center, Vicksburg, Mississippi 39180, USA
Toxicol Sci 116:523-32. 2010..In conclusion, these data indicate that tungsten produces complex results that must be carefully interpreted in the context of their respective animal models, as well as the phenotype of the cell lines (i.e., normal vs. cancerous)...
- Fate and toxicity of CuO nanospheres and nanorods used in Al/CuO nanothermites before and after combustionAlan J Kennedy
U S Army Engineer Research and Development Center, Environmental Laboratory, Building 3270, EP R, 3909 Halls Ferry Road, Vicksburg, Mississippi 39180, United States
Environ Sci Technol 47:11258-67. 2013..This study illustrates the importance of considering the fate and toxicology of nanoparticles in context with their relevant in-use applications. ..
- Tungsten toxicity, bioaccumulation, and compartmentalization into organisms representing two trophic levelsAlan J Kennedy
US Army Engineer Research and Development Center, Vicksburg, Mississippi 39180, United States
Environ Sci Technol 46:9646-52. 2012..Finally, synchrotron mapping provided evidence of tungsten in the inner layer of the snail shell, suggesting potential use of snail shells as a biomonitoring tool for metal contamination...
- Predicting chemical bioavailability using microarray gene expression data and regression modeling: A tale of three explosive compoundsPing Gong
Environmental Laboratory, US Army Engineer Research and Development Center, Vicksburg, MS, 39180, USA
BMC Genomics 17:205. 2016..In the present study, we further compared 18 different regression models and performed variable selection simultaneously with parameter estimation...
- Assessing the fate and effects of nano aluminum oxide in the terrestrial earthworm, Eisenia fetidaJessica G Coleman
U S Army Engineer Research and Development Center, Environmental Laboratory, 3909 Halls Ferry Road Vicksburg, Mississippi 39180, USA
Environ Toxicol Chem 29:1575-80. 2010..Results of the present study indicate that nano-sized Al2O3 may impact reproduction and behavior of E. fetida, although at high levels unlikely to be found in the environment...