Christy S Carter

Summary

Affiliation: Wake Forest University School of Medicine
Country: USA

Publications

  1. ncbi request reprint Assessment of physical function in aging rodents: a strategy for improving preclinical testing
    C S Carter
    Department of Internal Medicine, Section on Gerontology and Geriatrics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Exp Aging Res 27:271-82. 2001
  2. ncbi request reprint Physical performance and longevity in aged rats
    Christy S Carter
    Department of Internal Medicine, Section on Gerontology and Geriatrics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 57:B193-7. 2002
  3. ncbi request reprint Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats
    Christy S Carter
    Sticht Center on Aging, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 59:416-23. 2004
  4. ncbi request reprint Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span
    William E Sonntag
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157 1083, USA
    Endocrinology 146:2920-32. 2005
  5. pmc Differential effects of late-life initiation of low-dose enalapril and losartan on diastolic function in senescent Fischer 344 x Brown Norway male rats
    Leanne Groban
    Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1009, USA
    Age (Dordr) 34:831-43. 2012
  6. ncbi request reprint A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan
    Christy S Carter
    Dept Internal Medicine, Section on Gerontology and Geriatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157 1083, USA
    Trends Genet 18:295-301. 2002
  7. ncbi request reprint Growth hormone replacement attenuates diastolic dysfunction and cardiac angiotensin II expression in senescent rats
    Leanne Groban
    Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1009, USA
    J Gerontol A Biol Sci Med Sci 61:28-35. 2006
  8. pmc Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability
    Michelle M Adams
    Department of Neurobiology and Anatomy, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Exp Neurol 211:141-9. 2008
  9. ncbi request reprint Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging
    William E Sonntag
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston Salem, NC 27157 1083, USA
    Ageing Res Rev 4:195-212. 2005
  10. ncbi request reprint Models of growth hormone and IGF-1 deficiency: applications to studies of aging processes and life-span determination
    Christy S Carter
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1083, USA
    J Gerontol A Biol Sci Med Sci 57:B177-88. 2002

Detail Information

Publications16

  1. ncbi request reprint Assessment of physical function in aging rodents: a strategy for improving preclinical testing
    C S Carter
    Department of Internal Medicine, Section on Gerontology and Geriatrics, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Exp Aging Res 27:271-82. 2001
    ....
  2. ncbi request reprint Physical performance and longevity in aged rats
    Christy S Carter
    Department of Internal Medicine, Section on Gerontology and Geriatrics, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 57:B193-7. 2002
    ....
  3. ncbi request reprint Angiotensin-converting enzyme inhibition, body composition, and physical performance in aged rats
    Christy S Carter
    Sticht Center on Aging, Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    J Gerontol A Biol Sci Med Sci 59:416-23. 2004
    ..These results suggest that ACE inhibition may prevent age-related declines in physical performance, which may be mediated by a reduction in body fat mass...
  4. ncbi request reprint Adult-onset growth hormone and insulin-like growth factor I deficiency reduces neoplastic disease, modifies age-related pathology, and increases life span
    William E Sonntag
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston Salem, North Carolina 27157 1083, USA
    Endocrinology 146:2920-32. 2005
    ....
  5. pmc Differential effects of late-life initiation of low-dose enalapril and losartan on diastolic function in senescent Fischer 344 x Brown Norway male rats
    Leanne Groban
    Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1009, USA
    Age (Dordr) 34:831-43. 2012
    ....
  6. ncbi request reprint A critical analysis of the role of growth hormone and IGF-1 in aging and lifespan
    Christy S Carter
    Dept Internal Medicine, Section on Gerontology and Geriatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157 1083, USA
    Trends Genet 18:295-301. 2002
    ..Here, we critique the current mammalian models of GH/IGF-1 deficiency and discuss the actions of GH/IGF-1 on biological aging and lifespan...
  7. ncbi request reprint Growth hormone replacement attenuates diastolic dysfunction and cardiac angiotensin II expression in senescent rats
    Leanne Groban
    Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157 1009, USA
    J Gerontol A Biol Sci Med Sci 61:28-35. 2006
    ..Age-related decreases in GH and IGF-1 may contribute to the decline in diastolic function of aging, in part through alterations in renin-angiotensin system-mediated ventricular remodeling...
  8. pmc Caloric restriction and age affect synaptic proteins in hippocampal CA3 and spatial learning ability
    Michelle M Adams
    Department of Neurobiology and Anatomy, Wake Forest University Health Sciences, Winston Salem, NC 27157, USA
    Exp Neurol 211:141-9. 2008
    ..This age-related decrease and CR-induced stabilization are likely to affect CA3 synaptic plasticity and, as a result, hippocampal function...
  9. ncbi request reprint Growth hormone and insulin-like growth factor-1 (IGF-1) and their influence on cognitive aging
    William E Sonntag
    Department of Physiology and Pharmacology, Wake Forest University Health Sciences, Winston Salem, NC 27157 1083, USA
    Ageing Res Rev 4:195-212. 2005
    ..While these observations offer valuable insight into the influence of growth hormone and IGF-1 on neuronal events in the aged mammal, additional functional studies are required to link these changes to cognitive improvements...
  10. ncbi request reprint Models of growth hormone and IGF-1 deficiency: applications to studies of aging processes and life-span determination
    Christy S Carter
    Department of Physiology and Pharmacology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1083, USA
    J Gerontol A Biol Sci Med Sci 57:B177-88. 2002
    ..Finally, we propose an integrated explanation of growth hormone and IGF-1's contribution to the aging phenotype and life-span determination...
  11. ncbi request reprint Growth, metabolism, and blood pressure disturbances during aging in transgenic rats with altered brain renin-angiotensin systems
    Sherry O Kasper
    Hypertension and Vascular Disease Center, Physiology and Pharmacology Department, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1032, USA
    Physiol Genomics 23:311-7. 2005
    ..These data implicate glial angiotensinogen in the regulation of body metabolism as well as hormonal mechanisms regulating blood pressure...
  12. ncbi request reprint Lifelong caloric restriction and interleukin-6 secretion from adipose tissue: effects on physical performance decline in aged rats
    Tongjian You
    Department of Exercise and Nutrition Sciences, School of Public Health and Health Professions, The State University of New York at Buffalo, 214A Kimball Tower, Buffalo, NY 14214, USA
    J Gerontol A Biol Sci Med Sci 62:1082-7. 2007
    ..Therefore, CR may be an effective intervention for improving functional status into advanced age and is perhaps mediated via a reduction in adipose tissue-generated proinflammatory cytokine production...
  13. ncbi request reprint Effects of short-term GH supplementation and treadmill exercise training on physical performance and skeletal muscle apoptosis in old rats
    Emanuele Marzetti
    Department of Aging and Geriatrics, Institute on Aging, Division of Biology of Aging, University of Florida, 1600 SW Archer Road, Gainesville, FL 32610, USA
    Am J Physiol Regul Integr Comp Physiol 294:R558-67. 2008
    ..In contrast, short-term administration of GH late in life does not provide any protection against functional decline or muscle aging and may even accelerate apoptosis in slow-twitch muscles, such as the soleus...
  14. ncbi request reprint Angiotensin-converting enzyme inhibition intervention in elderly persons: effects on body composition and physical performance
    Christy S Carter
    University of Florida, Department of Aging and Geriatric Research, 1329 SW 16th St PO Box 100143, Gainesville FL, 32610 0143, USA
    J Gerontol A Biol Sci Med Sci 60:1437-46. 2005
    ..Promising pharmacoepidemiological studies and experimental evidence in animals suggest that there are appropriate models in which to study this effect...
  15. ncbi request reprint Anabolic effects of testosterone are preserved during inhibition of 5alpha-reductase
    Stephen E Borst
    Geriatric Research, Education, and Clinical Center, Veterans Affairs Medical Center, Gainesville, Florida 32608 1197, USA
    Am J Physiol Endocrinol Metab 293:E507-14. 2007
    ..Our study demonstrates that the effects of testosterone on muscle and bone can be separated from the prostate effects and provides a testable strategy for combating sarcopenia and osteopenia in older hypogonadal men...
  16. ncbi request reprint Molecular mechanisms of life- and health-span extension: role of calorie restriction and exercise intervention
    Christy S Carter
    Department of Aging and Geriatric Research, Division of Biology of Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA
    Appl Physiol Nutr Metab 32:954-66. 2007
    ....