Sudha Chaturvedi

Summary

Affiliation: Wadsworth Center
Country: USA

Publications

  1. pmc Molecular genetic analyses of mating pheromones reveal intervariety mating or hybridization in Cryptococcus neoformans
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, School of Public Health, State University of New York, Albany 12201 2002, USA
    Infect Immun 70:5225-35. 2002
  2. ncbi request reprint Selection of optimal host strain for molecular pathogenesis studies on Cryptococcus gattii
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208 2002, USA
    Mycopathologia 160:207-15. 2005
  3. doi request reprint Rapid real-time PCR assay for culture and tissue identification of Geomyces destructans: the etiologic agent of bat geomycosis (white nose syndrome)
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
    Mycopathologia 172:247-56. 2011
  4. pmc Morphological and molecular characterizations of psychrophilic fungus Geomyces destructans from New York bats with White Nose Syndrome (WNS)
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, USA
    PLoS ONE 5:e10783. 2010
  5. pmc Clonal genotype of Geomyces destructans among bats with White Nose Syndrome, New York, USA
    Sunanda S Rajkumar
    New York State Department of Health, Albany, New York, USA
    Emerg Infect Dis 17:1273-6. 2011
  6. ncbi request reprint Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulence
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    Mol Microbiol 55:1782-800. 2005
  7. pmc Transcription factor STE12alpha has distinct roles in morphogenesis, virulence, and ecological fitness of the primary pathogenic yeast Cryptococcus gattii
    Ping Ren
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, New York 12201 2002, USA
    Eukaryot Cell 5:1065-80. 2006
  8. pmc Extracellular fibrils of pathogenic yeast Cryptococcus gattii are important for ecological niche, murine virulence and human neutrophil interactions
    Deborah J Springer
    Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 5:e10978. 2010
  9. ncbi request reprint An efficient method for homologous gene reconstitution in Cryptococcus gattii using URA5 auxotrophic marker
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208 2002, USA
    Mycopathologia 162:401-9. 2006
  10. ncbi request reprint Characterization of Cu,Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: role in biology and virulence
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208 2002, USA
    Mol Microbiol 47:1681-94. 2003

Research Grants

  1. SUPEROXIDE DISMUTASE OF CRYPTOCOCCUS NEOFORMANS
    Sudha Chaturvedi; Fiscal Year: 2004
  2. Cryptococus neoformans SOD1p cellular trafficking
    Sudha Chaturvedi; Fiscal Year: 2005

Collaborators

Detail Information

Publications19

  1. pmc Molecular genetic analyses of mating pheromones reveal intervariety mating or hybridization in Cryptococcus neoformans
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, School of Public Health, State University of New York, Albany 12201 2002, USA
    Infect Immun 70:5225-35. 2002
    ..grubii is unrelated to, highly divergent from, or rarer than that in C. neoformans var. neoformans. These observations could form the basis for future studies on the role of intervariety mating in C. neoformans biology and virulence...
  2. ncbi request reprint Selection of optimal host strain for molecular pathogenesis studies on Cryptococcus gattii
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208 2002, USA
    Mycopathologia 160:207-15. 2005
    ..Based on these observations, we conclude that NIH444 should remain the strain of choice for understanding Cg pathogenesis, especially on the North American continent...
  3. doi request reprint Rapid real-time PCR assay for culture and tissue identification of Geomyces destructans: the etiologic agent of bat geomycosis (white nose syndrome)
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208, USA
    Mycopathologia 172:247-56. 2011
    ..destructans. Further trials and inter-laboratory comparisons of this novel assay are recommended to improve the diagnosis of bat geomycosis...
  4. pmc Morphological and molecular characterizations of psychrophilic fungus Geomyces destructans from New York bats with White Nose Syndrome (WNS)
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, USA
    PLoS ONE 5:e10783. 2010
    ..The fungus has been recovered sparsely despite plentiful availability of afflicted animals...
  5. pmc Clonal genotype of Geomyces destructans among bats with White Nose Syndrome, New York, USA
    Sunanda S Rajkumar
    New York State Department of Health, Albany, New York, USA
    Emerg Infect Dis 17:1273-6. 2011
    ..Multiple gene genealogic analyses were conducted on 16 fungal isolates from diverse sites in New York State during 2008-2010. The results are consistent with the clonal dispersal of a single G. destructans genotype...
  6. ncbi request reprint Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulence
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    Mol Microbiol 55:1782-800. 2005
    ..Thus, SOD1p and SOD2p play distinct roles in the biology and virulence of Cn var. gattii via independent modes of action...
  7. pmc Transcription factor STE12alpha has distinct roles in morphogenesis, virulence, and ecological fitness of the primary pathogenic yeast Cryptococcus gattii
    Ping Ren
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, New York 12201 2002, USA
    Eukaryot Cell 5:1065-80. 2006
    ..Thus, STE12alpha plays distinct roles in C. gattii morphogenesis, virulence, and ecological fitness...
  8. pmc Extracellular fibrils of pathogenic yeast Cryptococcus gattii are important for ecological niche, murine virulence and human neutrophil interactions
    Deborah J Springer
    Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 5:e10978. 2010
    ..Such ecological adaptation of C. gattii could play roles in enhanced virulence in mammalian hosts at least initially via inhibition of host PMN- mediated killing...
  9. ncbi request reprint An efficient method for homologous gene reconstitution in Cryptococcus gattii using URA5 auxotrophic marker
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208 2002, USA
    Mycopathologia 162:401-9. 2006
    ..This strategy was successfully used for the generation of Cg can2+CAN2/URA5 homologous reconstituted strains, which grew in ambient air to the wild-type level while can2 mutant exhibited severe growth defect under similar conditions...
  10. ncbi request reprint Characterization of Cu,Zn superoxide dismutase (SOD1) gene knock-out mutant of Cryptococcus neoformans var. gattii: role in biology and virulence
    Srinivas D Narasipura
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Ave, Albany, NY 12208 2002, USA
    Mol Microbiol 47:1681-94. 2003
    ..This report constitutes the first instance in which superoxide dismutase has been directly implicated in the virulence of a fungal pathogen...
  11. pmc Antifungal testing and high-throughput screening of compound library against Geomyces destructans, the etiologic agent of geomycosis (WNS) in bats
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 6:e17032. 2011
    ..Our results could provide a theoretical basis for future strategies aimed at the rehabilitation of most affected bat species and for decontamination of Gd in the cave environment...
  12. pmc Cryptococcus gattii in AIDS patients, southern California
    Sudha Chaturvedi
    Mycology Laboratory, Wadsworth Center, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    Emerg Infect Dis 11:1686-92. 2005
    ..The high prevalence of Cg was noteworthy, in view of its sporadic reports from AIDS patients in North America and its recent emergence as a primary pathogen on Vancouver Island, Canada...
  13. pmc Mycobiome of the bat white nose syndrome affected caves and mines reveals diversity of fungi and local adaptation by the fungal pathogen Pseudogymnoascus (Geomyces) destructans
    Tao Zhang
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 9:e108714. 2014
    ..These findings underscore the need for integrated disease control measures that target both bats and Pd in the hibernacula for the control of WNS. ..
  14. pmc Cryptococcus gattii: a resurgent fungal pathogen
    Vishnu Chaturvedi
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY 12208, USA
    Trends Microbiol 19:564-71. 2011
    ..Increased focus on epidemiology, ecological modeling and host-pathogen interactions is expected to yield a better understanding of this enigmatic yeast, and ultimately lead to better measures for its control...
  15. doi request reprint Development of an Agrobacterium-mediated transformation system for the cold-adapted fungi Pseudogymnoascus destructans and P. pannorum
    Tao Zhang
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, NY, USA
    Fungal Genet Biol 81:73-81. 2015
    ..The homologous recombination in transformants was 3.1% for Pd and 16.7% for Pp. The availability of a standardized ATMT system would allow future molecular genetic analyses of Pd and related cold-adapted fungi. ..
  16. pmc Real-time PCR assay for identification of Blastomyces dermatitidis in culture and in tissue
    Ketevan Sidamonidze
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, USA
    J Clin Microbiol 50:1783-6. 2012
    ..dermatitidis. No cross-reactivity was observed against other fungal DNA. The assay allowed rapid (5-h) identification of B. dermatitidis from culture and from clinical specimens...
  17. pmc Molecular characterization, biofilm analysis and experimental biofouling study of Fusarium isolates from recent cases of fungal keratitis in New York State
    Madhu Dyavaiah
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, NY 12208 2002, USA
    BMC Ophthalmol 7:1. 2007
    ..To characterize Fusarium isolates from recent cases of fungal keratitis in contact lens wearers, and to investigate fungal association with MoistureLoc solution...
  18. pmc Novel Trichoderma polysporum Strain for the Biocontrol of Pseudogymnoascus destructans, the Fungal Etiologic Agent of Bat White Nose Syndrome
    Tao Zhang
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America
    PLoS ONE 10:e0141316. 2015
    ..These results suggest that Tp WPM 39143 is a promising candidate for further evaluation as a biocontrol agent of Pd in WNS affected sites. ..
  19. pmc Carbon dioxide is a powerful inducer of monokaryotic hyphae and spore development in Cryptococcus gattii and carbonic anhydrase activity is dispensable in this dimorphic transition
    Ping Ren
    Mycology Laboratory, Wadsworth Center, New York State Department of Health, 120 New Scotland Avenue, Albany, New York, United States of America
    PLoS ONE 9:e113147. 2014
    ..Both can1 and can2 mutants retained full pathogenic potential in vitro and in vivo. These results provide insight into C. gattii adaptation for arboreal growth and production of infectious propagules by β-CA independent mechanism(s). ..

Research Grants2

  1. SUPEROXIDE DISMUTASE OF CRYPTOCOCCUS NEOFORMANS
    Sudha Chaturvedi; Fiscal Year: 2004
    ....
  2. Cryptococus neoformans SOD1p cellular trafficking
    Sudha Chaturvedi; Fiscal Year: 2005
    ..The results of this investigation are likely to substantially enhance our understanding of protein trafficking in pathogenic fungi in general, and possibly assist in search for new therapeutic targets. ..