Affiliation: Virginia Commonwealth University
- Examining the latent class structure of CO2 hypersensitivity using time course trajectories of panic response systemsRoxann Roberson-Nay
Virginia Commonwealth University, Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Richmond, VA, USA Electronic address
J Behav Ther Exp Psychiatry 47:68-76. 2015..The goal of the current study was to explore the latent class trajectories of three primary response systems theoretically associated with CO2 hypersensitivity: subjective anxiety, panic symptoms, and respiratory rate (fR)...
- Characteristics of individuals meeting criteria for new onset panic attacks following exposure to a typhoonRoxann Roberson-Nay
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA Electronic address
Psychiatry Res 209:574-8. 2013....
- Evidence for distinct genetic effects associated with response to 35% CO₂Roxann Roberson-Nay
Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA 23298, USA
Depress Anxiety 30:259-66. 2013..People with a history of panic attacks or panic disorder are particularly prone to anxious response, suggesting that CO2 hypersensitivity is a robust risk marker of panic spectrum vulnerability...
- Childhood separation anxiety disorder and adult onset panic attacks share a common genetic diathesisRoxann Roberson-Nay
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia 23298, USA
Depress Anxiety 29:320-7. 2012....
- A latent class approach to the external validation of respiratory and non-respiratory panic subtypesR Roberson-Nay
Department of Psychiatry, Virginia Commonwealth University, Virginia Institute for Psychiatric and Behavioral Genetics, P O Box 980489, Richmond, VA 23298, USA
Psychol Med 42:461-74. 2012..e. severity) dimension only; or (3) qualitatively from one another...
- Carbon dioxide hypersensitivity in separation-anxious offspring of parents with panic disorderRoxann Roberson-Nay
Virginia Commonwealth University, Department of Psychiatry, Richmond, VA, USA
Biol Psychiatry 67:1171-7. 2010..This study examines the influence of familial risk for PD on CO(2) responses in children with SAD. We hypothesized that offspring with SAD of parents with PD would have distinct CO(2) responses...
- Increased amygdala activity during successful memory encoding in adolescent major depressive disorder: An FMRI studyRoxann Roberson-Nay
Section on Development and Affective Neuroscience, National Institute of Mental Health Intramural Research Program, Bethesda, Maryland, USA
Biol Psychiatry 60:966-73. 2006..This study tests the hypothesis that adolescent MDD is associated with abnormal amygdala activity during evocative-face viewing...
- Panic disorder and its subtypes: a comprehensive analysis of panic symptom heterogeneity using epidemiological and treatment seeking samplesR Roberson-Nay
Virginia Commonwealth University, PO Box 980489, Richmond, VA 23298, USA
Psychol Med 41:2411-21. 2011..The present study represents the most comprehensive examination of phenotypic variance in PD with and without agoraphobia for the purpose of identifying clinically relevant and etiologically meaningful subtypes...
- Response to 5% carbon dioxide in children and adolescents: relationship to panic disorder in parents and anxiety disorders in subjectsDaniel S Pine
Section on Development and Affective Neuroscience, National Institute of Mental Health Intramural Research Program, Bethesda, MD 20817, USA
Arch Gen Psychiatry 62:73-80. 2005..Exaggerated responses to CO(2) inhalation have been reported in adults with PD and their unaffected adult relatives, as well as in clinic-referred children with anxiety disorders...
- A developmental examination of amygdala response to facial expressionsAmanda E Guyer
National Institutes of Health NIH, Bethesda, MD 20892 2670, USA
J Cogn Neurosci 20:1565-82. 2008....
- Striatal functional alteration in adolescents characterized by early childhood behavioral inhibitionAmanda E Guyer
Emotional Development and Affective Neuroscience Branch, National Institute of Mental Health, National Institutes of Health NIH, Bethesda, Maryland 20892, USA
J Neurosci 26:6399-405. 2006....
- Stress responsivity and HPA axis activity in juveniles: results from a home-based CO2 inhalation studyThomas A Terleph
NIMH, NIH, Bldg 15 K, Rm 110, MSC 2670, Bethesda, MD 20817 2670, USA
Am J Psychiatry 163:738-40. 2006..The current home-based study tested the hypothesis that parental panic disorder and offspring response to CO(2) are associated with elevated cortisol levels in juvenile offspring...
- Limbic hyperactivation during processing of neutral facial expressions in children with bipolar disorderBrendan A Rich
Mood and Anxiety Program, National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892 2670, USA
Proc Natl Acad Sci U S A 103:8900-5. 2006..Results implicate deficient emotion-attention interactions in the pathophysiology of BD in youth and suggest that developmental psychobiology approaches to chronic mental illness have broad applicability...
- Neural activation during encoding of emotional faces in pediatric bipolar disorderDaniel P Dickstein
Division of Intramural Research Program, National Institute of Mental Health, Pediatrics and Developmental Neuropsychiatry Branch, Bethesda, MD 20892 2670, USA
Bipolar Disord 9:679-92. 2007..To begin to address these limitations, the current study tests the hypothesis that pediatric BD (PBD) subjects exhibit altered neural activation during encoding of emotional faces compared to typically developing controls...
- The Inventory of Callous-Unemotional Traits (ICU) in Children: Reliability and HeritabilityAshlee A Moore
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, P O Box 980489, Richmond, VA, 23298, USA
Behav Genet . 2016..This is the first study to account for measurement error while examining the heritability of CU traits, furthering our understanding of psychopathy in children...
- Fear conditioning in adolescents with anxiety disorders: results from a novel experimental paradigmJennifer Y F Lau
Mood and Anxiety Disorders Program, National Institute of Mental Health National Institutes of Health, 15K North Drive, MSC 2670, Bethesda, MD 20892 2670, USA
J Am Acad Child Adolesc Psychiatry 47:94-102. 2008..Adult data suggest that anxiety disorders involve elevated fear but intact differential conditioning. We used a novel paradigm to assess fear conditioning in pediatric anxiety patients...
- The Twin Study of Negative Valence Emotional ConstructsDever M Carney
Virginia Institute for Psychiatric and Behavioral Genetics and Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, USA
Twin Res Hum Genet 19:456-64. 2016..The findings will potentially expand our understanding of the mechanisms by which genetic and environmental factors contribute to individual differences in NVS phenotypes and provide new insights into underlying risk factors for IDs. ..
- Longitudinal course of panic disorder with and without agoraphobia using the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)William Nay
Virginia Commonwealth University, Department of Psychiatry, P O Box 980253, Richmond, VA 23298 0253, USA
Psychiatry Res 208:54-61. 2013..Similarly, the current study suggests clinicians pay particular attention to concurrent factors relevant to relapse in PD/PDA that may also be clinically addressed (e.g., co-morbid MDD/GAD and nicotine dependence)...
- Validation of candidate anxiety disorder genes using a carbon dioxide challenge taskJeanne E Savage
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, VA, USA Electronic address
Biol Psychol 109:61-6. 2015..The use of endophenotypic markers is a promising avenue for gene identification in anxiety and other complex disorders. ..
- The genetics of anxiety-related negative valence system traitsJeanne E Savage
Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond, Virginia
Am J Med Genet B Neuropsychiatr Genet . 2016..Thus, more research is required to provide a firm understanding of the genetic aspects of anxiety-related NVS constructs. © 2016 Wiley Periodicals, Inc...
- Longitudinal Stability of Genetic and Environmental Influences on Irritability: From Childhood to Young AdulthoodRoxann Roberson-Nay
From the Department of Psychiatry and the Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University, Richmond the Section on Bipolar Spectrum Disorders, Division of Intramural Research Programs, NIMH, Bethesda, Md and the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm
Am J Psychiatry 172:657-64. 2015..This study examined the temporal pattern of genetic and environmental effects on irritability using data from a prospective, four-wave longitudinal twin study...
- Associations among trauma, posttraumatic stress disorder, cannabis use, and cannabis use disorder in a nationally representative epidemiologic sampleSalpi Kevorkian
Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University
Psychol Addict Behav 29:633-8. 2015..Longitudinal research investigating patterns of onset of these events/disorders is needed...
- Development of an abbreviated Social Phobia and Anxiety Inventory (SPAI) using item response theory: the SPAI-23Roxann Roberson-Nay
Virginia Commonwealth University, Department of Psychiatry, Richmond, VA 23298 0489, USA
Psychol Assess 19:133-45. 2007..The SPAI-23 has considerable practical benefits, including a screening of both social and agoraphobic anxiety as well as decreased assessment and scoring time...
- Attention alters neural responses to evocative faces in behaviorally inhibited adolescentsKoraly Perez-Edgar
Department of Psychology, George Mason University, USA
Neuroimage 35:1538-46. 2007..These patterns of reactivity may help sustain early temperamental biases over time and contribute to the observed relation between BI and anxiety...
- Memory deficits in children with and at risk for anxiety disordersRoma A Vasa
Johns Hopkins University School of Medicine, Baltimore, Maryland 21211, USA
Depress Anxiety 24:85-94. 2007..These findings are relevant to understanding the phenomenology of childhood anxiety disorders and may provide insights into the neural circuits underlying these disorders...
- Does major depressive disorder in parents predict specific fears and phobias in offspring?Matthew G Biel
Department of Child and Adolescent Psychiatry, NYU Child Study Center, NYU School of Medicine, New York University, New York, USA
Depress Anxiety 25:379-82. 2008..Elevated rates of specific fears in offspring of parents with MDD+anxiety disorder may be a function of more severe parental psychopathology, increased genetic loading, or unmeasured environmental influences...
- Parenting behaviors in parents with anxiety disordersSamuel M Turner
Maryland Center for Anxiety Disorders, Department of Psychology, University of Maryland, College Park, MD 20742, USA
Behav Res Ther 41:541-54. 2003..The results are discussed in terms of how parenting behaviors might influence the development of maladaptive anxiety via social learning and information transfer, and their heuristic implications...