Mark J Koury

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. ncbi request reprint New insights into erythropoiesis
    Mark J Koury
    Department of Medicine, Vanderbilt University, and Nashville Veterans Administration Medical Centers, Nashville, Tennessee 37232 6305, USA
    Curr Opin Hematol 9:93-100. 2002
  2. ncbi request reprint Erythropoietin: the story of hypoxia and a finely regulated hematopoietic hormone
    Mark J Koury
    Department of Medicine, VA Tennessee Valley Healthcare System and Vanderbilt University School of Medicine, Nashville, TN 37212, USA
    Exp Hematol 33:1263-70. 2005
  3. doi request reprint Tracking erythroid progenitor cells in times of need and times of plenty
    Mark J Koury
    Division of Hematology Oncology, Vanderbilt University School of Medicine, Nashville, Tennessee Electronic address
    Exp Hematol 44:653-63. 2016
  4. doi request reprint Abnormal erythropoiesis and the pathophysiology of chronic anemia
    Mark J Koury
    Division of Hematology Oncology, Vanderbilt University and Veterans Affairs Tennessee Valley Healthcare System, 777 Preston Research Building, Nashville, TN 37232, USA Electronic address
    Blood Rev 28:49-66. 2014
  5. doi request reprint How to approach chronic anemia
    Mark J Koury
    Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Hematology Am Soc Hematol Educ Program 2012:183-90. 2012
  6. ncbi request reprint Sugar coating extends half-lives and improves effectiveness of cytokine hormones
    Mark J Koury
    Vanderbilt University and Veterans Affairs Medical Center, 777 Preston Research Building, 2220 Pierce Avenue, Nashville, TN 37232 6307, USA
    Trends Biotechnol 21:462-4. 2003
  7. ncbi request reprint New insights into erythropoiesis: the roles of folate, vitamin B12, and iron
    Mark J Koury
    Department of Medicine, Vanderbilt University School of Medicine and Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee 37232, USA
    Annu Rev Nutr 24:105-31. 2004
  8. ncbi request reprint In vitro maturation of nascent reticulocytes to erythrocytes
    Mark J Koury
    Tennessee Valley Healthcare System Veterans Affairs Medical Center and Division of Hematology Oncology, Department of Medicine, 777 Preston Research Building, Vanderbilt University, Nashville, TN 37232 6307, USA
    Blood 105:2168-74. 2005
  9. pmc Adherence to macrophages in erythroblastic islands enhances erythroblast proliferation and increases erythrocyte production by a different mechanism than erythropoietin
    Melissa M Rhodes
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA
    Blood 111:1700-8. 2008
  10. pmc Bcl-x(L) prevents apoptosis of late-stage erythroblasts but does not mediate the antiapoptotic effect of erythropoietin
    Melissa M Rhodes
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37212, USA
    Blood 106:1857-63. 2005

Collaborators

Detail Information

Publications20

  1. ncbi request reprint New insights into erythropoiesis
    Mark J Koury
    Department of Medicine, Vanderbilt University, and Nashville Veterans Administration Medical Centers, Nashville, Tennessee 37232 6305, USA
    Curr Opin Hematol 9:93-100. 2002
    ..In reticulocyte maturation, regulated degradation of internal organelles involves a lipoxygenase, whereas survival requires the antiapoptotic protein Bcl-x...
  2. ncbi request reprint Erythropoietin: the story of hypoxia and a finely regulated hematopoietic hormone
    Mark J Koury
    Department of Medicine, VA Tennessee Valley Healthcare System and Vanderbilt University School of Medicine, Nashville, TN 37212, USA
    Exp Hematol 33:1263-70. 2005
    ....
  3. doi request reprint Tracking erythroid progenitor cells in times of need and times of plenty
    Mark J Koury
    Division of Hematology Oncology, Vanderbilt University School of Medicine, Nashville, Tennessee Electronic address
    Exp Hematol 44:653-63. 2016
    ..Clinical applications of information learned from studies of erythropoietic expansion, in terms of current therapies for anemia, are reviewed. ..
  4. doi request reprint Abnormal erythropoiesis and the pathophysiology of chronic anemia
    Mark J Koury
    Division of Hematology Oncology, Vanderbilt University and Veterans Affairs Tennessee Valley Healthcare System, 777 Preston Research Building, Nashville, TN 37232, USA Electronic address
    Blood Rev 28:49-66. 2014
    ....
  5. doi request reprint How to approach chronic anemia
    Mark J Koury
    Division of Hematology Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Hematology Am Soc Hematol Educ Program 2012:183-90. 2012
    ....
  6. ncbi request reprint Sugar coating extends half-lives and improves effectiveness of cytokine hormones
    Mark J Koury
    Vanderbilt University and Veterans Affairs Medical Center, 777 Preston Research Building, 2220 Pierce Avenue, Nashville, TN 37232 6307, USA
    Trends Biotechnol 21:462-4. 2003
    ....
  7. ncbi request reprint New insights into erythropoiesis: the roles of folate, vitamin B12, and iron
    Mark J Koury
    Department of Medicine, Vanderbilt University School of Medicine and Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee 37232, USA
    Annu Rev Nutr 24:105-31. 2004
    ..Erythroblast heme levels regulate uptake of iron and globin synthesis such that iron deficiency causes anemia by retarded production rates with smaller, less hemoglobinized erythrocytes...
  8. ncbi request reprint In vitro maturation of nascent reticulocytes to erythrocytes
    Mark J Koury
    Tennessee Valley Healthcare System Veterans Affairs Medical Center and Division of Hematology Oncology, Department of Medicine, 777 Preston Research Building, Vanderbilt University, Nashville, TN 37232 6307, USA
    Blood 105:2168-74. 2005
    ....
  9. pmc Adherence to macrophages in erythroblastic islands enhances erythroblast proliferation and increases erythrocyte production by a different mechanism than erythropoietin
    Melissa M Rhodes
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA
    Blood 111:1700-8. 2008
    ..These results suggest a mechanism for the development of anemias associated with abnormal macrophage function and for reduced responsiveness of those anemias to erythropoietin therapy...
  10. pmc Bcl-x(L) prevents apoptosis of late-stage erythroblasts but does not mediate the antiapoptotic effect of erythropoietin
    Melissa M Rhodes
    Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37212, USA
    Blood 106:1857-63. 2005
    ..Bcl-x(L) is not required for heme synthesis and does not mediate the antiapoptotic effects of erythropoietin, but it prevents ineffective erythropoiesis due to apoptosis in late-stage, hemoglobin-synthesizing erythroblasts...
  11. pmc Eto2/MTG16 and MTGR1 are heteromeric corepressors of the TAL1/SCL transcription factor in murine erythroid progenitors
    Ying Cai
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Biochem Biophys Res Commun 390:295-301. 2009
    ..These results identify Eto2 and Mtgr1 as authentic interaction partners of Tal1 and suggest they act as heteromeric corepressors of this bHLH transcription factor during erythroid differentiation...
  12. pmc Stress reticulocytes lose transferrin receptors by an extrinsic process involving spleen and macrophages
    Melissa M Rhodes
    Departments of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee
    Am J Hematol 91:875-82. 2016
    ..Am. J. Hematol. 91:875-882, 2016. © 2016 Wiley Periodicals, Inc. ..
  13. ncbi request reprint S-Adenosylhomocysteine: a better indicator of vascular disease than homocysteine?
    Conrad Wagner
    Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Am J Clin Nutr 86:1581-5. 2007
    ....
  14. pmc Recruitment of the SWI/SNF protein Brg1 by a multiprotein complex effects transcriptional repression in murine erythroid progenitors
    Zhixiong Xu
    Department of Medicine, Vanderbilt University, Nashville, TN 37232, USA
    Biochem J 399:297-304. 2006
    ..2, and most likely other genes, is actively repressed until the terminal differentiation of erythroid progenitors...
  15. ncbi request reprint Relationship between plasma S-adenosylhomocysteine concentration and glomerular filtration rate in children
    Kathy Jabs
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA
    Metabolism 55:252-7. 2006
    ..We suggest that plasma Hcy elevations that have been linked to vascular disease may be due to elevated SAH resulting from renal insufficiency...
  16. ncbi request reprint Macrophage apolipoprotein E reduces atherosclerosis and prevents premature death in apolipoprotein E and scavenger receptor-class BI double-knockout mice
    Hong Yu
    Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37232 6300, USA
    Arterioscler Thromb Vasc Biol 26:150-6. 2006
    ..The current study examines the ability of macrophage apoE to improve the dyslipidemia, reduce atherosclerosis, and rescue the lethal phenotype of DKO mice...
  17. pmc Maturational loss of the vitamin C transporter in erythrocytes
    James M May
    Department of Medicine, Vanderbilt University School of Medicine, 715 Preston Research Building, Nashville, TN 37232 6303, USA
    Biochem Biophys Res Commun 360:295-8. 2007
    ..Rates of specific ascorbate transport correlated with the presence of the SVCT2. These results show that mature erythrocytes fail to concentrate ascorbate due to the loss of SVCT2 during maturation in the bone marrow...
  18. ncbi request reprint Plasma S-adenosylhomocysteine versus homocysteine as a marker for vascular disease
    Conrad Wagner
    J Nutr 138:980; author reply 981. 2008
  19. ncbi request reprint Mechanism of protein sorting during erythroblast enucleation: role of cytoskeletal connectivity
    James C M Lee
    Department of Biological Engineering, University of Missouri Columbia, USA
    Blood 103:1912-9. 2004
    ..Further, we suggest that the enhanced rigidity of reticulocyte membranes observed in earlier investigations results, at least in part, from increased connectivity of GPA with the spectrin-based skeleton...
  20. pmc Nuclear substructure reorganization during late-stage erythropoiesis is selective and does not involve caspase cleavage of major nuclear substructural proteins
    Sharon Wald Krauss
    Life Sciences Division, University of California Lawrence Berkeley National Laboratory, Bldg 74, 1 Cyclotron Rd, Berkeley, CA 94720, USA
    Blood 106:2200-5. 2005
    ..These findings imply that nuclear condensation and extrusion during terminal erythroid differentiation involve novel mechanisms that do not entail major activation of apoptotic machinery...