John R Koethe

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Effects on mortality of a nutritional intervention for malnourished HIV-infected adults referred for antiretroviral therapy: a randomised controlled trial
    Suzanne Filteau
    Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    BMC Med 13:17. 2015
  2. pmc A 12 week longitudinal study of microbial translocation and systemic inflammation in undernourished HIV-infected Zambians initiating antiretroviral therapy
    Ashley Canipe
    Vanderbilt Institute for Global Health, Nashville, TN, USA
    BMC Infect Dis 14:521. 2014
  3. pmc Serum Phosphate Predicts Early Mortality among Underweight Adults Starting ART in Zambia: A Novel Context for Refeeding Syndrome?
    John R Koethe
    Centre for Infectious Diseases Research in Zambia, Plot 1275 Lubuto Road, P O Box 34681, Lusaka 10101, Zambia Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, A2200 MCN, 1161 21st Avenue South, Nashville, TN 37232 2582, USA Vanderbilt Institute for Global Health, 2525 West End Avenue, Suite 750, Nashville, TN 37203, USA
    J Nutr Metab 2013:545439. 2013
  4. pmc An association between adiposity and serum levels of macrophage inflammatory protein-1α and soluble CD14 in HIV-infected adults: results from a cross-sectional study
    John R Koethe
    Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN, USA
    Antivir Ther 18:729-33. 2013
  5. pmc Circulating interleukin-6, soluble CD14, and other inflammation biomarker levels differ between obese and nonobese HIV-infected adults on antiretroviral therapy
    John R Koethe
    Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN 37232 2582, USA
    AIDS Res Hum Retroviruses 29:1019-25. 2013
  6. pmc Self-reported dietary intake and appetite predict early treatment outcome among low-BMI adults initiating HIV treatment in sub-Saharan Africa
    John R Koethe
    Centre for Infectious Diseases Research in Zambia, Lusaka, Zambia
    Public Health Nutr 16:549-58. 2013
  7. pmc Serum leptin level mediates the association of body composition and serum C-reactive protein in HIV-infected persons on antiretroviral therapy
    John R Koethe
    Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2582, USA
    AIDS Res Hum Retroviruses 28:552-7. 2012
  8. pmc Physician specialization and women's primary care services in an urban HIV clinic
    John R Koethe
    Vandervilt University School of Medicine, Nashville, Tennessee 37232 2582, USA
    AIDS Patient Care STDS 22:373-80. 2008
  9. pmc An optimal body mass index range associated with improved immune reconstitution among HIV-infected adults initiating antiretroviral therapy
    John R Koethe
    Department of Medicine, Division of Infectious Diseases, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Clin Infect Dis 53:952-60. 2011
  10. pmc Nutrition and inflammation serum biomarkers are associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia
    John R Koethe
    Centre for Infectious Diseases Research in Zambia, Plot 1275 Lubuto Road, Lusaka, Zambia
    J Int AIDS Soc 14:19. 2011

Detail Information

Publications29

  1. pmc Effects on mortality of a nutritional intervention for malnourished HIV-infected adults referred for antiretroviral therapy: a randomised controlled trial
    Suzanne Filteau
    Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK
    BMC Med 13:17. 2015
    ..We hypothesized that short-course, high-dose vitamin and mineral supplementation in lipid nutritional supplements would decrease mortality...
  2. pmc A 12 week longitudinal study of microbial translocation and systemic inflammation in undernourished HIV-infected Zambians initiating antiretroviral therapy
    Ashley Canipe
    Vanderbilt Institute for Global Health, Nashville, TN, USA
    BMC Infect Dis 14:521. 2014
    ....
  3. pmc Serum Phosphate Predicts Early Mortality among Underweight Adults Starting ART in Zambia: A Novel Context for Refeeding Syndrome?
    John R Koethe
    Centre for Infectious Diseases Research in Zambia, Plot 1275 Lubuto Road, P O Box 34681, Lusaka 10101, Zambia Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, A2200 MCN, 1161 21st Avenue South, Nashville, TN 37232 2582, USA Vanderbilt Institute for Global Health, 2525 West End Avenue, Suite 750, Nashville, TN 37203, USA
    J Nutr Metab 2013:545439. 2013
    ..The association of low pretreatment serum phosphate level and early ART mortality among undernourished individuals may represent a variant of the refeeding syndrome. Further studies of cellular metabolism in this population are needed...
  4. pmc An association between adiposity and serum levels of macrophage inflammatory protein-1α and soluble CD14 in HIV-infected adults: results from a cross-sectional study
    John R Koethe
    Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN, USA
    Antivir Ther 18:729-33. 2013
    ....
  5. pmc Circulating interleukin-6, soluble CD14, and other inflammation biomarker levels differ between obese and nonobese HIV-infected adults on antiretroviral therapy
    John R Koethe
    Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, TN 37232 2582, USA
    AIDS Res Hum Retroviruses 29:1019-25. 2013
    ....
  6. pmc Self-reported dietary intake and appetite predict early treatment outcome among low-BMI adults initiating HIV treatment in sub-Saharan Africa
    John R Koethe
    Centre for Infectious Diseases Research in Zambia, Lusaka, Zambia
    Public Health Nutr 16:549-58. 2013
    ..We assessed relationships between appetite, dietary intake and treatment outcome 12 weeks after ART initiation among HIV-infected adults with advanced malnutrition and immunosuppression...
  7. pmc Serum leptin level mediates the association of body composition and serum C-reactive protein in HIV-infected persons on antiretroviral therapy
    John R Koethe
    Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee 37232 2582, USA
    AIDS Res Hum Retroviruses 28:552-7. 2012
    ....
  8. pmc Physician specialization and women's primary care services in an urban HIV clinic
    John R Koethe
    Vandervilt University School of Medicine, Nashville, Tennessee 37232 2582, USA
    AIDS Patient Care STDS 22:373-80. 2008
    ..Our results show potential for improvements in care among both generalist and ID-specialist physicians treating HIV-positive women...
  9. pmc An optimal body mass index range associated with improved immune reconstitution among HIV-infected adults initiating antiretroviral therapy
    John R Koethe
    Department of Medicine, Division of Infectious Diseases, Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    Clin Infect Dis 53:952-60. 2011
    ....
  10. pmc Nutrition and inflammation serum biomarkers are associated with 12-week mortality among malnourished adults initiating antiretroviral therapy in Zambia
    John R Koethe
    Centre for Infectious Diseases Research in Zambia, Plot 1275 Lubuto Road, Lusaka, Zambia
    J Int AIDS Soc 14:19. 2011
    ..The relationship between nutrition and inflammation-related serum biomarkers and early treatment outcomes (e.g., less than 90 days) in this population is not well described...
  11. pmc Early immunologic response and subsequent survival among malnourished adults receiving antiretroviral therapy in Urban Zambia
    John R Koethe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    AIDS 24:2117-21. 2010
    ..To evaluate the relationship between early CD4(+) lymphocyte recovery on antiretroviral therapy (ART) and subsequent survival among low body mass index (BMI) HIV-1-infected adults...
  12. doi request reprint Dyspnea and hemoptysis in a 53-year-old woman with a history of breast cancer
    John R Koethe
    Department of Infectious Diseases, Vanderbilt University Medical Center, South Twenty First Ave and Garland Ave, Nashville, TN 37232, USA
    Chest 133:1248-51. 2008
  13. pmc Macronutrient supplementation for malnourished HIV-infected adults: a review of the evidence in resource-adequate and resource-constrained settings
    John R Koethe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    Clin Infect Dis 49:787-98. 2009
    ....
  14. pmc Association between weight gain and clinical outcomes among malnourished adults initiating antiretroviral therapy in Lusaka, Zambia
    John R Koethe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    J Acquir Immune Defic Syndr 53:507-13. 2010
    ..To describe the association between 6-month weight gain on antiretroviral therapy (ART) and subsequent clinical outcomes...
  15. pmc Nutritional aspects of HIV-associated wasting in sub-Saharan Africa
    John R Koethe
    Division of Infectious Diseases, Vanderbilt University, Nashville, TN 37232 2582, USA
    Am J Clin Nutr 91:1138S-1142S. 2010
    ..We close by highlighting priority areas for future research...
  16. pmc Serum phosphate predicts early mortality in adults starting antiretroviral therapy in Lusaka, Zambia: a prospective cohort study
    Douglas C Heimburger
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    PLoS ONE 5:e10687. 2010
    ..We assessed the association of serum phosphate with early mortality among HIV-infected adults with severe malnutrition and/or advanced immunosuppression...
  17. pmc Non-AIDS-defining events among HIV-1-infected adults receiving combination antiretroviral therapy in resource-replete versus resource-limited urban setting
    C William Wester
    Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    AIDS 25:1471-9. 2011
    ..To compare incidence and distribution of non-AIDS-defining events (NADEs) among HIV-1-infected adults receiving combination antiretroviral therapy (cART) in urban sub-Saharan African versus United States settings...
  18. pmc HIV testing service awareness and service uptake among female heads of household in rural Mozambique: results from a province-wide survey
    Heather N Paulin
    Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, 1611 21st Avenue South, A 2200, Medical Center North, Nashville, TN, USA
    BMC Public Health 15:132. 2015
    ..6%), poverty, and suboptimal health service access and utilization...
  19. pmc Higher Time-Updated Body Mass Index: Association With Improved CD4+ Cell Recovery on HIV Treatment
    John R Koethe
    Departments of Medicine and Biostatistics, Vanderbilt University School of Medicine, Nashville, TN Departments of Epidemiology and Medicine, Johns Hopkins University, Baltimore, MD Kaiser Permanente Northern California, Oakland, CA Southern Alberta HIV Clinic, Calgary, AB, Canada Department of Internal Medicine, Universidad Central del Caribe, Bayamon, Puerto Rico Department of Medicine, University of Alabama at Birmingham, Birmingham, AL Department of Biostatistics, Harvard School of Public Health, Boston, MA Kaiser Permanente, Mid Atlantic Permanente Research Institute, Rockville, MD and Veterans Affairs Connecticut Healthcare System, West Haven, and Yale University School of Medicine and Public Health, New Haven, CT
    J Acquir Immune Defic Syndr 73:197-204. 2016
    ..We assessed the longitudinal relationship between body mass index (BMI) and CD4 cell recovery on ART in a large, multisite cohort to identify potential physiologic links between adiposity and CD4 cell expansion...
  20. pmc Cardiometabolic risk factors among HIV patients on antiretroviral therapy
    James N Kiage
    Department of Medicine, Division of Epidemiology, Vanderbilt University, Nashville, TN 37203, USA
    Lipids Health Dis 12:50. 2013
    ..HIV and combination antiretroviral therapy (cART) may increase cardiovascular disease (CVD) risk. We assessed the early effects of cART on CVD risk markers in a population with presumed low CVD risk...
  21. pmc A cluster randomized trial of routine HIV-1 viral load monitoring in Zambia: study design, implementation, and baseline cohort characteristics
    John R Koethe
    Centre for Infectious Disease Research in Zambia, Lusaka, Zambia
    PLoS ONE 5:e9680. 2010
    ....
  22. pmc Superior Glucose Tolerance and Metabolomic Profiles, Independent of Adiposity, in HIV-Infected Women Compared With Men on Antiretroviral Therapy
    John R Koethe
    From the Division of Infectious Diseases JRK, TRS Department of Biostatistics CAJ, BES, Vanderbilt University School of Medicine, Nashville, TN and Sanford Burnham Prebys Metabolomics Core at the Southeast Center for Integrated Metabolomics, University of Florida CP, JC, Gainesville, FL
    Medicine (Baltimore) 95:e3634. 2016
    ..The relationship between sex and plasma metabolite levels did not significantly differ according to HIV-status among obese subjects, suggesting the observed sex-differences may not be specific to HIV infection. ..
  23. pmc From Wasting to Obesity: The Contribution of Nutritional Status to Immune Activation in HIV Infection
    John R Koethe
    Division of Infectious Diseases Vanderbilt Institute for Global Health, Nashville, Tennessee
    J Infect Dis 214:S75-82. 2016
    ....
  24. pmc Effects on anthropometry and appetite of vitamins and minerals given in lipid nutritional supplements for malnourished HIV-infected adults referred for antiretroviral therapy: results from the NUSTART randomized controlled trial
    Andrea M Rehman
    Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom Mwanza Research Centre, National Institute for Medical Research, Mwanza, Tanzania University Teaching Hospital, Lusaka, Zambia Vanderbilt University School of Medicine, Nashville, TN Department of Gastroenterology, Queen Mary University of London, London, United Kingdom and Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark
    J Acquir Immune Defic Syndr 68:405-12. 2015
    ..The evidence base for effects of nutritional interventions for malnourished HIV-infected patients starting antiretroviral therapy (ART) is limited and inconclusive...
  25. doi request reprint Acute kidney injury after placement of an antibiotic-impregnated cement spacer during revision total knee arthroplasty
    Travis J Menge
    Department of Orthopaedic Surgery, Vanderbilt University School of Medicine, MCE South Tower, Nashville, Tennessee 37232 8774, USA
    J Arthroplasty 27:1221-7.e1-2. 2012
    ..00-1.52; P = .049). Routine monitoring of serum creatinine and measurement of serum aminoglycoside levels in response to a threshold creatinine rise may be warranted after the placement of an aminoglycoside-containing ACS...
  26. pmc Rising Obesity Prevalence and Weight Gain Among Adults Starting Antiretroviral Therapy in the United States and Canada
    John R Koethe
    1 Vanderbilt University School of Medicine, Nashville, Tennessee
    AIDS Res Hum Retroviruses 32:50-8. 2016
    ..The high prevalence of obesity we observed among ART-exposed HIV-infected adults in North America may contribute to health complications in the future. ..
  27. pmc The metabolic and cardiovascular consequences of obesity in persons with HIV on long-term antiretroviral therapy
    John R Koethe
    aDivision of Infectious DiseasesbDepartment of MedicinecDepartment of BiostatisticsdDepartment of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    AIDS 30:83-91. 2016
    ..This study assessed the effect of obesity on metabolic and cardiovascular disease risk factors in HIV-infected adults on antiretroviral therapy with sustained virologic suppression...
  28. ncbi request reprint Association of T Cell and Macrophage Activation with Arterial Vascular Health in HIV
    Heather N Grome
    1 Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee
    AIDS Res Hum Retroviruses . 2016
    ..Both innate and cellular immune activation appear to promote arterial vascular disease in HIV-infected persons on ART using differing mechanisms...
  29. doi request reprint HIV testing service awareness and service uptake among female heads of household in rural Mozambique: results from a province-wide survey
    Heather N Paulin
    Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, 1611 21st Avenue South, A 2200, Medical Center North, Nashville, TN, USA
    BMC Public Health 15:1388. 2015
    ..6%), poverty, and suboptimal health service access and utilization...