Qingxia Chen

Summary

Affiliation: Vanderbilt University
Country: USA

Publications

  1. pmc Theory and Inference for Regression Models with Missing Responses and Covariates
    Qingxia Chen
    Qingxia Chen is Assistant Professor, Department of Biostatistics, Vanderbilt University, Nashville, TN 37232, Email Joseph G Ibrahim is Professor, Department of Biostatistics, University of North Carolina, McGavran Greenberg Hall, Chapel Hill, NC 27599, Email Ming Hui Chen is Professor, Department of Statistics, University of Connecticut, 215 Glenbrook Road, U 4120, Storrs, CT 06269 4120, Email Pralay Senchaudhuri is Director of Cytel Software Corporation, Cambridge, MA 02139, Email
    J Multivar Anal 99:1302-1331. 2008
  2. pmc Too many covariates and too few cases? - a comparative study
    Qingxia Chen
    Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, 37232, TN, U S A
    Stat Med 35:4546-4558. 2016
  3. pmc Quantifying the average of the time-varying hazard ratio via a class of transformations
    Qingxia Chen
    Department of Biostatistics, Vanderbilt University, Nashville, TN, 37232, USA
    Lifetime Data Anal 21:259-79. 2015
  4. ncbi request reprint Semiparametric models for missing covariate and response data in regression models
    Qingxia Chen
    Department of Biostatistics, Vanderbilt University, Nashville, Tennessee 37232, USA
    Biometrics 62:177-84. 2006
  5. pmc Effectiveness of seasonal vaccine in preventing confirmed influenza-associated hospitalizations in community dwelling older adults
    H Keipp Talbot
    Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Infect Dis 203:500-8. 2011
  6. pmc Evaluating the case-positive, control test-negative study design for influenza vaccine effectiveness for the frailty bias
    H Keipp Talbot
    Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States Electronic address
    Vaccine 34:1806-9. 2016
  7. pmc Bayesian gamma frailty models for survival data with semi-competing risks and treatment switching
    Yuanye Zhang
    Novartis Institutes for BioMedical Research, Inc, 220 Massachusetts Avenue, Cambridge, MA, 02139, USA
    Lifetime Data Anal 20:76-105. 2014
  8. doi request reprint Effectiveness of influenza vaccine for preventing laboratory-confirmed influenza hospitalizations in adults, 2011-2012 influenza season
    H Keipp Talbot
    Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Clin Infect Dis 56:1774-7. 2013
  9. pmc The financial impact of health information exchange on emergency department care
    Mark E Frisse
    Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
    J Am Med Inform Assoc 19:328-33. 2012
  10. pmc The feasibility of text reminders to improve medication adherence in adolescents with asthma
    Kevin B Johnson
    Department of Biomedical Informatics at Vanderbilt University School of Medicine, Nashville, TN, USA Department of Pediatrics at Vanderbilt University School of Medicine, Nashville, TN, USA
    J Am Med Inform Assoc 23:449-55. 2016

Collaborators

Detail Information

Publications34

  1. pmc Theory and Inference for Regression Models with Missing Responses and Covariates
    Qingxia Chen
    Qingxia Chen is Assistant Professor, Department of Biostatistics, Vanderbilt University, Nashville, TN 37232, Email Joseph G Ibrahim is Professor, Department of Biostatistics, University of North Carolina, McGavran Greenberg Hall, Chapel Hill, NC 27599, Email Ming Hui Chen is Professor, Department of Statistics, University of Connecticut, 215 Glenbrook Road, U 4120, Storrs, CT 06269 4120, Email Pralay Senchaudhuri is Director of Cytel Software Corporation, Cambridge, MA 02139, Email
    J Multivar Anal 99:1302-1331. 2008
    ..In addition, a theoretical investigation of bias for the CC method is also carried out. A simulation study and real dataset are given to illustrate the methodology...
  2. pmc Too many covariates and too few cases? - a comparative study
    Qingxia Chen
    Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, 37232, TN, U S A
    Stat Med 35:4546-4558. 2016
    ..Ridge regression and penalized logistic regression models that penalize all but the coefficient of the exposure may be considered in these types of studies. Copyright © 2016 John Wiley & Sons, Ltd...
  3. pmc Quantifying the average of the time-varying hazard ratio via a class of transformations
    Qingxia Chen
    Department of Biostatistics, Vanderbilt University, Nashville, TN, 37232, USA
    Lifetime Data Anal 21:259-79. 2015
    ..Statist Med 28:2473-2489, 2009), with a similar magnitude of power loss when the hazards cross. The proposed estimates and test statistics are applied to a colorectal cancer clinical trial. ..
  4. ncbi request reprint Semiparametric models for missing covariate and response data in regression models
    Qingxia Chen
    Department of Biostatistics, Vanderbilt University, Nashville, Tennessee 37232, USA
    Biometrics 62:177-84. 2006
    ..Maximum likelihood estimates are then obtained via the EM algorithm. Simulations are given to demonstrate the methodology, and a real data set from a melanoma cancer clinical trial is analyzed using the proposed methods...
  5. pmc Effectiveness of seasonal vaccine in preventing confirmed influenza-associated hospitalizations in community dwelling older adults
    H Keipp Talbot
    Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA
    J Infect Dis 203:500-8. 2011
    ..Current evidence supporting the effectiveness of influenza vaccine in preventing hospitalizations in older adults is insufficient...
  6. pmc Evaluating the case-positive, control test-negative study design for influenza vaccine effectiveness for the frailty bias
    H Keipp Talbot
    Departments of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States Electronic address
    Vaccine 34:1806-9. 2016
    ..Previous influenza vaccine effectiveness studies were criticized for their failure to control for frailty. This study was designed to see if the test-negative study design overcomes this bias...
  7. pmc Bayesian gamma frailty models for survival data with semi-competing risks and treatment switching
    Yuanye Zhang
    Novartis Institutes for BioMedical Research, Inc, 220 Massachusetts Avenue, Cambridge, MA, 02139, USA
    Lifetime Data Anal 20:76-105. 2014
    ..A simulation study is conducted to examine the empirical performance of DIC and LPML and as well as the posterior estimates. The proposed method is further applied to analyze data from a colorectal cancer study. ..
  8. doi request reprint Effectiveness of influenza vaccine for preventing laboratory-confirmed influenza hospitalizations in adults, 2011-2012 influenza season
    H Keipp Talbot
    Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Clin Infect Dis 56:1774-7. 2013
    ..Influenza vaccination was verified in 35% (6/17) of adults with influenza-associated hospitalizations compared to 64% (97/152) of test-negative controls; adjusted vaccine effectiveness was 71.4% (95% confidence interval, 17.1%-94.9%)...
  9. pmc The financial impact of health information exchange on emergency department care
    Mark E Frisse
    Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee 37203, USA
    J Am Med Inform Assoc 19:328-33. 2012
    ..To examine the financial impact health information exchange (HIE) in emergency departments (EDs)...
  10. pmc The feasibility of text reminders to improve medication adherence in adolescents with asthma
    Kevin B Johnson
    Department of Biomedical Informatics at Vanderbilt University School of Medicine, Nashville, TN, USA Department of Pediatrics at Vanderbilt University School of Medicine, Nashville, TN, USA
    J Am Med Inform Assoc 23:449-55. 2016
    ..The goal of this study was to assess the impact of MyMediHealth (MMH) - a website and a short messaging service (SMS)-based reminder system - on medication adherence and perceived self-efficacy in adolescents with asthma...
  11. pmc A study of transportability of an existing smoking status detection module across institutions
    Mei Liu
    Department of Biomedical Informatics, School of Medicine, Vanderbilt University, Nashville, TN, USA
    AMIA Annu Symp Proc 2012:577-86. 2012
    ..Our results showed that the customized module achieved significantly higher F-measures at all levels of classification (i.e., sentence, document, patient) compared to the direct application of the cTAKES module to the Vanderbilt data...
  12. pmc Adjustment for missingness using auxiliary information in semiparametric regression
    Donglin Zeng
    Department of Biostatistics, University of North Carolina, USA
    Biometrics 66:115-22. 2010
    ..A set of real data is used to illustrate our approach...
  13. pmc Health information exchange usage in emergency departments and clinics: the who, what, and why
    Kevin B Johnson
    Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA
    J Am Med Inform Assoc 18:690-7. 2011
    ..Understanding approaches taken by existing successful exchanges can help new exchange efforts determine goals and plan implementations. The goal of this study was to explore characteristics of use and users of a successful regional HIE...
  14. pmc An assessment of pharmacists' readiness for paperless labeling: a national survey
    Yun Xian Ho
    Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Am Med Inform Assoc 21:43-8. 2014
    ..To assess the state of readiness for the adoption of paperless labeling among a nationally representative sample of pharmacies, including chain pharmacies, independent retail pharmacies, hospitals, and other rural or urban dispensing sites...
  15. pmc Human rhinovirus C associated with wheezing in hospitalised children in the Middle East
    E Kathryn Miller
    Department of Pediatrics, Vanderbilt University, Nashville, TN, USA
    J Clin Virol 46:85-9. 2009
    ..Few studies have investigated the disease burden and genetic diversity of human rhinoviruses (HRVs) in developing countries...
  16. pmc Safety and immunogenicity of trivalent inactivated influenza vaccine in infants
    Natasha B Halasa
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Infect Dis 197:1448-54. 2008
    ..Trivalent inactivated influenza vaccine (TIV) is not licensed for use in infants <6 months old, the group with the highest influenza hospitalization rates among children...
  17. pmc Estimating treatment effects with treatment switching via semicompeting risks models: an application to a colorectal cancer study
    Donglin Zeng
    Department of Biostatistics, CB 7420, University of North Carolina, Chapel Hill, North Carolina 27516, U S A
    Biometrika 99:167-184. 2012
    ..The proposed method is applied to data from a colorectal cancer clinical trial...
  18. pmc Assessing adolescent asthma symptoms and adherence using mobile phones
    Shelagh A Mulvaney
    School of Nursing, Vanderbilt University School of Medicine, Nashville, TN, United States
    J Med Internet Res 15:e141. 2013
    ..Ecological momentary assessment (EMA) of health behaviors using mobile phones offers a promising alternative to assessing adherence and collecting related data that can be clinically useful for adherence problem solving...
  19. pmc A novel approach to supporting relationship-centered care through electronic health record ergonomic training in preclerkship medical education
    Howard Silverman
    Dr Silverman is chair and professor, Department of Biomedical Informatics, and Professor, Departments of Family and Community Medicine and Bioethics and Medical Humanism, University of Arizona College of Medicine Phoenix, Phoenix, Arizona, and clinical professor of biomedical informatics, Arizona State University, Tempe, Arizona Dr Ho is research manager, Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, Tennessee Dr Kaib is assistant director, Doctoring Program, and Assistant Clinical Professor, Department of Family and Community Medicine, University of Arizona College of Medicine Phoenix, Phoenix, Arizona Dr Ellis is behavioral health director, Scottsdale Healthcare Family Medicine Residency and Scottsdale Healthcare NOAH Neighborhood Outreach Access to Health clinics, Scottsdale, Arizona, and Instructor, Department of Family and Community Medicine, University of Arizona College of Medicine Phoenix, Phoenix, Arizona Dr Moffitt is director, Doctoring Program, and associate professor of internal medicine, University of Arizona College of Medicine Phoenix, Phoenix, Arizona Dr Chen is assistant professor, Departments of Biostatistics and Biomedical Informatics, Vanderbilt University, Nashville, Tennessee Ms Nian is a biostatistician, Department of Biostatistics, Vanderbilt University Medical Center
    Acad Med 89:1230-4. 2014
    ..How can physicians incorporate the electronic health record (EHR) into clinical practice in a relationship-enhancing fashion ("EHR ergonomics")?..
  20. pmc User perspectives on the usability of a regional health information exchange
    Cynthia S Gadd
    Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee 37203, USA
    J Am Med Inform Assoc 18:711-6. 2011
    ..This grant-funded HIE had been deployed rapidly to address the imminent needs of the patient population and the need to draw wider participation from regional entities...
  21. pmc Gamma frailty transformation models for multivariate survival times
    Donglin Zeng
    Department of Biostatistics, University of North Carolina, 3105 D McGavran Greenberg Hall, Campus Box 7420, Chapel Hill, North Carolina, 27516, U S A
    Biometrika 96:277-291. 2009
    ..Simulation studies show that the proposed estimation procedure provides asymptotically efficient estimates and yields good inferential properties for small sample sizes. The method is illustrated using data from a cardiovascular study...
  22. pmc Assessment of parental acceptance of a potential cytomegalovirus vaccine for adolescent females
    Tiffany J Petty
    Meharry Medical College, Nashville, TN, USA
    Vaccine 28:5686-90. 2010
    ..These findings provide initial data on factors that are likely to influence parental acceptance of a CMV vaccine for adolescent girls...
  23. pmc Influenza in older adults: impact of vaccination of school children
    H Keipp Talbot
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, United States
    Vaccine 27:1923-7. 2009
    ..59, 2.04) in the intervention county and 1.53 (95% CI 0.71, 2.34) in the control county. These rates did not differ significantly except in the subgroup aged 50 -- 64 years where rates in the intervention county were significantly lower...
  24. doi request reprint Potential impact of acceleration of the pertussis vaccine primary series for infants
    Myrick C Shinall
    School of Medicine, Divinity School, Vanderbilt University, Nashville, Tennessee, USA
    Pediatrics 122:1021-6. 2008
    ....
  25. pmc Bayesian modeling and inference for clinical trials with partial retrieved data following dropout
    Qingxia Chen
    Department of Biostatistics, Vanderbilt University, Nashville, TN 37232, USA
    Stat Med 32:4180-95. 2013
    ..We examine various properties of the proposed model. We develop an efficient Markov chain Monte Carlo sampling algorithm. We analyze in detail via the proposed method a real dataset from a clinical trial...
  26. ncbi request reprint Providers' beliefs, attitudes, and behaviors before implementing a computerized pneumococcal vaccination reminder
    Judith W Dexheimer
    Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA
    Acad Emerg Med 13:1312-8. 2006
    ..The emergency department (ED) has been recommended as a suitable setting for offering pneumococcal vaccination; however, implementations of ED vaccination programs remain scarce...
  27. pmc Bayesian Case-deletion Model Complexity and Information Criterion
    Hongtu Zhu
    Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599
    Stat Interface 7:531-542. 2014
    ..We illustrate the proposed methodology on linear mixed models with simulations and a real data example...
  28. pmc Human metapneumovirus in hospitalized children in Amman, Jordan
    Syed Asad Ali
    Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, USA
    J Med Virol 82:1012-6. 2010
    ..Longer surveillance studies are needed to better understand the seasonal epidemiology of HMPV and to assess if co-infection with HMPV and RSV leads to more severe illness...
  29. doi request reprint Performing without a net: transitioning away from a health information technology-rich training environment
    Kevin Johnson
    Vanderbilt University, Nashville, Tennessee, USA
    Acad Med 83:1179-86. 2008
    ..The authors conducted this study to determine how transitioning from an HIT-rich environment affects practitioners' self-perceptions of competence, practice efficiency, and patient safety...
  30. pmc Joint modeling of longitudinal and survival data with missing and left-censored time-varying covariates
    Qingxia Chen
    Department of Biostatistics, Vanderbilt University, Nashville, TN, 37232, U S A Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, 37232, U S A
    Stat Med 33:4560-76. 2014
    ..A Bayesian analysis is conducted on the MACS data using the proposed joint model. The proposed method is shown to improve the precision of estimates when compared with alternative methods...
  31. pmc Extracting and integrating data from entire electronic health records for detecting colorectal cancer cases
    Hua Xu
    Department of Biomedical Informatics, Vanderbilt University, School of Medicine, Nashville, TN, USA
    AMIA Annu Symp Proc 2011:1564-72. 2011
    ..996 for document level concept identification, and 0.93 for patient level case detection...
  32. doi request reprint Pentoxifylline lowers plasminogen activator inhibitor 1 levels in obese individuals: a pilot study
    James A S Muldowney
    Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA
    Angiology 63:429-34. 2012
    ..These findings suggest that these markers of cardiovascular risk are differentially regulated in obesity and that PAI-1 levels can be reduced by pentoxifylline in this population...
  33. pmc Suboptimal inhibition of platelet cyclooxygenase-1 by aspirin in metabolic syndrome
    James P Smith
    Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA
    Hypertension 59:719-25. 2012
    ..In conclusion, metabolic syndrome, which places patients at high risk for thrombotic cardiovascular events, strongly and uniquely associates with less effective inhibition of platelet COX-1 by aspirin...
  34. pmc Impact of generic substitution decision support on electronic prescribing behavior
    Shane P Stenner
    Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Am Med Inform Assoc 17:681-8. 2010
    ..To evaluate the impact of generic substitution decision support on electronic (e-) prescribing of generic medications...