Kanda S Ramasamy
Affiliation: Valeant Pharmaceuticals International
- Solid-phase parallel synthesis of 4-beta-D-ribofuranosylpyrazolo[4,3-d]pyrimidine nucleosidesKanda S Ramasamy
R and D Division, Valeant Pharmaceuticals, Costa Mesa, California 92626, USA
Nucleosides Nucleotides Nucleic Acids 24:1947-70. 2005..Cleavage of the products from the solid support with 30% HFIP in a parallel fashion yielded nucleoside libraries simultaneously, and they were analyzed and characterized by high-throughput LC-MS...
- Synthesis of pyrrolo[2,3-d]pyrimidine nucleoside derivatives as potential anti-HCV agentsChamakura V N S Varaprasad
Drug Discovery, Valeant Pharmaceuticals Research and Development, 3300 Hyland Avenue, Costa Mesa, CA 92626, USA
Bioorg Chem 35:25-34. 2007..Among the compounds examined 4-methylthio (18) and 5-carboxamide oxime derivatives (23 and 27) of Toyocamycin were found to have good activity and selectivity...