Timothy W Collette

Summary

Affiliation: U.S. Environmental Protection Agency
Country: USA

Publications

  1. doi request reprint Metabolite profiles of repeatedly sampled urine from male fathead minnows (Pimephales promelas) contain unique lipid signatures following exposure to anti-androgens
    Timothy W Collette
    U S EPA, National Exposure Research Laboratory, Athens, GA 30605, USA Electronic address
    Comp Biochem Physiol Part D Genomics Proteomics 19:190-8. 2016
  2. ncbi request reprint The role of Raman spectroscopy in the analytical chemistry of potable water
    Timothy W Collette
    UlS Environmental Protection Agency, National Exposure Research Laboratory, Athens, GA 30605, USA
    J Environ Monit 4:27-34. 2002
  3. ncbi request reprint Analysis of hydroponic fertilizer matrixes for perchlorate: comparison of analytical techniques
    Timothy W Collette
    United States Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, 960 College Station Road, Athens, GA 30605, USA
    Analyst 128:88-97. 2003
  4. doi request reprint Impacts of an anti-androgen and an androgen/anti-androgen mixture on the metabolite profile of male fathead minnow urine
    Timothy W Collette
    Office of Research and Development, National Exposure Research Laboratory, U S Environmental Protection Agency, 960 College Station Rd, Athens, Georgia 30605, USA
    Environ Sci Technol 44:6881-6. 2010
  5. doi request reprint Use of gene expression, biochemical and metabolite profiles to enhance exposure and effects assessment of the model androgen 17β-trenbolone in fish
    Drew R Ekman
    U S Environmental Protection Agency, Athens, Georgia, USA
    Environ Toxicol Chem 30:319-29. 2011
  6. doi request reprint Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin
    John M Davis
    National Exposure Research Laboratory, US Environmental Protection Agency, Athens, Georgia
    Environ Toxicol Chem 35:2493-2502. 2016
  7. doi request reprint Impacts of 17α-ethynylestradiol exposure on metabolite profiles of zebrafish (Danio rerio) liver cells
    Quincy Teng
    National Exposure Research Laboratory, US Environmental Protection Agency, Athens, GA 30605, United States
    Aquat Toxicol 130:184-91. 2013
  8. ncbi request reprint Raman spectroscopy-based metabolomics for differentiating exposures to triazole fungicides using rat urine
    Daniel P Cherney
    U S Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, Athens, Georgia 30605, USA
    Anal Chem 79:7324-32. 2007
  9. ncbi request reprint Degradation of chlorpyrifos in aqueous chlorine solutions: pathways, kinetics, and modeling
    Stephen E Duirk
    National Exposure Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Athens, Georgia 30605, USA
    Environ Sci Technol 40:546-51. 2006
  10. doi request reprint Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action
    Gerald T Ankley
    USEPA, National Health and Environmental Effects Research Lab, Duluth, MN, USA
    Aquat Toxicol 92:168-78. 2009

Detail Information

Publications13

  1. doi request reprint Metabolite profiles of repeatedly sampled urine from male fathead minnows (Pimephales promelas) contain unique lipid signatures following exposure to anti-androgens
    Timothy W Collette
    U S EPA, National Exposure Research Laboratory, Athens, GA 30605, USA Electronic address
    Comp Biochem Physiol Part D Genomics Proteomics 19:190-8. 2016
    ..In addition, GC-MS allowed us to identify several lipids (e.g., certain saturated fatty acids) in mFHM urine as candidate markers of exposure to androgen receptor antagonists. ..
  2. ncbi request reprint The role of Raman spectroscopy in the analytical chemistry of potable water
    Timothy W Collette
    UlS Environmental Protection Agency, National Exposure Research Laboratory, Athens, GA 30605, USA
    J Environ Monit 4:27-34. 2002
    ..The goal of this article is to give the environmental scientist with no specialized knowledge of the topic just enough theory and background to evaluate the utility of this rapidly developing analytical tool...
  3. ncbi request reprint Analysis of hydroponic fertilizer matrixes for perchlorate: comparison of analytical techniques
    Timothy W Collette
    United States Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, 960 College Station Road, Athens, GA 30605, USA
    Analyst 128:88-97. 2003
    ..This ore, which is the only well-established natural source of perchlorate, is mined and used, albeit minimally, as a nitrogen source in some fertilizer products...
  4. doi request reprint Impacts of an anti-androgen and an androgen/anti-androgen mixture on the metabolite profile of male fathead minnow urine
    Timothy W Collette
    Office of Research and Development, National Exposure Research Laboratory, U S Environmental Protection Agency, 960 College Station Rd, Athens, Georgia 30605, USA
    Environ Sci Technol 44:6881-6. 2010
    ..The relative occurrence of male-like nuptial tubercles in female FHM exposed to TB and to the mixtures of TB and CA supported the metabolomics data...
  5. doi request reprint Use of gene expression, biochemical and metabolite profiles to enhance exposure and effects assessment of the model androgen 17β-trenbolone in fish
    Drew R Ekman
    U S Environmental Protection Agency, Athens, Georgia, USA
    Environ Toxicol Chem 30:319-29. 2011
    ..Furthermore, TRB appeared to induce the hepatic metabolome of females to become more like that of males at both high test concentrations of TRB (472 ng/L) and more environmentally relevant levels (33 ng/L)...
  6. doi request reprint Linking field-based metabolomics and chemical analyses to prioritize contaminants of emerging concern in the Great Lakes basin
    John M Davis
    National Exposure Research Laboratory, US Environmental Protection Agency, Athens, Georgia
    Environ Toxicol Chem 35:2493-2502. 2016
    ..Environ Toxicol Chem 2016;35:2493-2502. Published 2016 Wiley Periodicals Inc. on behalf of SETAC. This article is a US Government work and, as such, is in the public domain in the United States of America...
  7. doi request reprint Impacts of 17α-ethynylestradiol exposure on metabolite profiles of zebrafish (Danio rerio) liver cells
    Quincy Teng
    National Exposure Research Laboratory, US Environmental Protection Agency, Athens, GA 30605, United States
    Aquat Toxicol 130:184-91. 2013
    ..The results of this study demonstrate the potential of cell-based metabolomics to assess chemical exposure and toxicity for regulatory application...
  8. ncbi request reprint Raman spectroscopy-based metabolomics for differentiating exposures to triazole fungicides using rat urine
    Daniel P Cherney
    U S Environmental Protection Agency, Office of Research and Development, National Exposure Research Laboratory, Athens, Georgia 30605, USA
    Anal Chem 79:7324-32. 2007
    ..Results from multivariate data analysis demonstrated that the Raman method compares favorably with NMR in regard to the ability to differentiate responses from these three contaminants...
  9. ncbi request reprint Degradation of chlorpyrifos in aqueous chlorine solutions: pathways, kinetics, and modeling
    Stephen E Duirk
    National Exposure Research Laboratory, Office of Research and Development, US Environmental Protection Agency, Athens, Georgia 30605, USA
    Environ Sci Technol 40:546-51. 2006
    ....
  10. doi request reprint Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action
    Gerald T Ankley
    USEPA, National Health and Environmental Effects Research Lab, Duluth, MN, USA
    Aquat Toxicol 92:168-78. 2009
    ..Although our project is focused specifically on EDCs in fish, we believe that the basic conceptual approach has utility for systematically assessing exposure and effects of chemicals with other MOA across a variety of biological systems...
  11. doi request reprint Push-through direct injection NMR: an optimized automation method applied to metabolomics
    Quincy Teng
    National Exposure Research Laboratory, U S EPA, 960 College Station Road, Athens, GA 30605, USA
    Analyst 137:2226-32. 2012
    ..While simple in concept and setup, this new method provides a substantial improvement over current approaches...
  12. doi request reprint Chlorpyrifos transformation by aqueous chlorine in the presence of bromide and natural organic matter
    Stephen E Duirk
    Office of Research and Development, National Exposure Research Laboratory, U S Environmental Protection Agency, Athens, GA 30605, USA
    J Agric Food Chem 56:1328-35. 2008
    ..A mechanistic model was used to adequately predict the loss of CP as well as the formation of CPO and the hydrolysis product 3,5,6-trichloro-2-pyridinol (TCP) in the presence of the ACC water...
  13. ncbi request reprint Monitoring the speciation of aqueous free chlorine from pH 1 to 12 with Raman spectroscopy to determine the identity of the potent low-pH oxidant
    Daniel P Cherney
    U S Environmental Protection Agency, National Exposure Research Laboratory, 960 College Station Rd, Athens, Georgia 30605, USA
    Appl Spectrosc 60:764-72. 2006
    ..These and other results reported here argue strongly that Cl2(aq) is the correct form of the potent low-pH oxidant in aqueous free-chlorine solutions...