Wenjun Bao

Summary

Affiliation: U.S. Environmental Protection Agency
Country: USA

Publications

  1. ncbi request reprint A database for tracking toxicogenomic samples and procedures
    Wenjun Bao
    Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Reprod Toxicol 19:411-9. 2005
  2. ncbi request reprint Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides
    Amber K Goetz
    Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 215:274-84. 2006
  3. ncbi request reprint Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides
    Douglas B Tully
    Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 215:260-73. 2006
  4. doi request reprint Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays
    Barbara A Wetmore
    The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709 2137, USA
    Toxicol Sci 132:327-46. 2013
  5. doi request reprint Use of short-term transcriptional profiles to assess the long-term cancer-related safety of environmental and industrial chemicals
    Russell S Thomas
    The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 112:311-21. 2009
  6. ncbi request reprint Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data
    Jennifer Fostel
    LIMT Lockheed Martin Information Technology LMIT, Research Triangle Park, NC 27709, USA
    Toxicol Sci 88:585-601. 2005
  7. ncbi request reprint Evaluation of external RNA controls for the assessment of microarray performance
    Weida Tong
    National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Rd, Jefferson, Arkansas 72079, USA
    Nat Biotechnol 24:1132-9. 2006
  8. pmc The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
    Leming Shi
    National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA
    Nat Biotechnol 24:1151-61. 2006
  9. pmc Comparison of transcriptional responses in liver tissue and primary hepatocyte cell cultures after exposure to hexahydro-1, 3, 5-trinitro-1, 3, 5-triazine
    Edward J Perkins
    US Army Engineer Research and Development Center, 3909 Halls Ferry Road, Vicksburg, MS, USA
    BMC Bioinformatics 7:S22. 2006
  10. pmc The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies
    Leming Shi
    National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    BMC Bioinformatics 9:S10. 2008

Detail Information

Publications11

  1. ncbi request reprint A database for tracking toxicogenomic samples and procedures
    Wenjun Bao
    Reproductive Toxicology Division, National Health and Environmental Effects Research Laboratory, Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Reprod Toxicol 19:411-9. 2005
    ..The user-friendly interface provides easy procedures for researchers to add, edit, save, delete, and navigate different records. Finally, TSP facilitates exporting microarray data into public databases...
  2. ncbi request reprint Gene expression profiling in the liver of CD-1 mice to characterize the hepatotoxicity of triazole fungicides
    Amber K Goetz
    Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 215:274-84. 2006
    ..Based on these results, we expanded on our original hypothesis that triazole hepatotoxicity was mediated by CYP induction, to include additional XME genes, many of which are modulated by CAR and PXR...
  3. ncbi request reprint Gene expression profiling in liver and testis of rats to characterize the toxicity of triazole fungicides
    Douglas B Tully
    Office of Research and Development, U S Environmental Protection Agency, Research Triangle Park, NC 27711, USA
    Toxicol Appl Pharmacol 215:260-73. 2006
    ..Triazoles also affected expression of multiple genes involved in steroid hormone metabolism in the two tissues. Thus, gene expression profiles helped identify possible toxicological mechanisms of the triazole fungicides...
  4. doi request reprint Relative impact of incorporating pharmacokinetics on predicting in vivo hazard and mode of action from high-throughput in vitro toxicity assays
    Barbara A Wetmore
    The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709 2137, USA
    Toxicol Sci 132:327-46. 2013
    ....
  5. doi request reprint Use of short-term transcriptional profiles to assess the long-term cancer-related safety of environmental and industrial chemicals
    Russell S Thomas
    The Hamner Institutes for Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Toxicol Sci 112:311-21. 2009
    ....
  6. ncbi request reprint Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data
    Jennifer Fostel
    LIMT Lockheed Martin Information Technology LMIT, Research Triangle Park, NC 27709, USA
    Toxicol Sci 88:585-601. 2005
    ..To illustrate the utility of the CEBS-DD, we present an example of integrating data from two proteomics and transcriptomics studies of the response to acute acetaminophen toxicity (A. N. Heinloth et al., 2004, Toxicol. Sci. 80, 193-202)...
  7. ncbi request reprint Evaluation of external RNA controls for the assessment of microarray performance
    Weida Tong
    National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Rd, Jefferson, Arkansas 72079, USA
    Nat Biotechnol 24:1132-9. 2006
    ..This multiplatform investigation of the behavior and utility of ERCs provides a basis for articulating specific recommendations for their future use in evaluating assay performance across multiple platforms...
  8. pmc The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements
    Leming Shi
    National Center for Toxicological Research, US Food and Drug Administration, Jefferson, Arkansas 72079, USA
    Nat Biotechnol 24:1151-61. 2006
    ..This study provides a resource that represents an important first step toward establishing a framework for the use of microarrays in clinical and regulatory settings...
  9. pmc Comparison of transcriptional responses in liver tissue and primary hepatocyte cell cultures after exposure to hexahydro-1, 3, 5-trinitro-1, 3, 5-triazine
    Edward J Perkins
    US Army Engineer Research and Development Center, 3909 Halls Ferry Road, Vicksburg, MS, USA
    BMC Bioinformatics 7:S22. 2006
    ..In this work, we compare transcriptional responses in livers of Sprague-Dawley rats and primary hepatocyte cells after exposure to RDX to determine how faithfully the in vitro model system reflects in vivo responses...
  10. pmc The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies
    Leming Shi
    National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Road, Jefferson, AR 72079, USA
    BMC Bioinformatics 9:S10. 2008
    ..The resultant variety of existing and emerging methods exacerbates confusion and continuing debate in the microarray community on the appropriate choice of methods for identifying reliable DEG lists...
  11. ncbi request reprint Performance comparison of one-color and two-color platforms within the MicroArray Quality Control (MAQC) project
    Tucker A Patterson
    National Center for Toxicological Research, US Food and Drug Administration, 3900 NCTR Rd, Jefferson, Arkansas 72079, USA
    Nat Biotechnol 24:1140-50. 2006
    ....