Neil A Zakai
Affiliation: University of Vermont
- D-dimer and the Risk of Stroke and Coronary Heart Disease. The REasons for Geographic and Racial Differences in Stroke (REGARDS) StudyNeil A Zakai
Neil A Zakai, MD MSc, University of Vermont College of Medicine, 208 South Park Drive, Colchester, VT 05446, USA, Tel 1 802 6563154, Fax 1 802 656 8965, E mail
Thromb Haemost . 2016..These findings highlight potential different pathophysiology of vascular disease by disease site and race suggesting potential further studies targeting haemostasis in primary prevention of vascular disease...
- Venous thrombosis risk assessment in medical inpatients: the medical inpatients and thrombosis (MITH) studyN A Zakai
University of Vermont College of Medicine and Fletcher Allen Health Care, Colchester, VT 05446, USA
J Thromb Haemost 11:634-41. 2013..We sought to define the risk factors present at admission for venous thromboembolism (VTE) in medical inpatients and develop a risk model for clinical use...
- Hemoglobin decline, function, and mortality in the elderly: the cardiovascular health studyNeil A Zakai
Departments of Medicine and Pathology, University of Vermont, Burlington, Vermont College of Medicine, USA
Am J Hematol 88:5-9. 2013..These data may allow clinicians to identify at-risk elderly individuals for early intervention to improve the quality and quantity of life...
- Total tissue factor pathway inhibitor and venous thrombosis. The Longitudinal Investigation of Thromboembolism EtiologyNeil A Zakai
Department of Medicine and Pathology, Colchester Research Facility, University of Vermont College of Medicine, Colchester, VT 05446, USA
Thromb Haemost 104:207-12. 2010..93 (1.05, 3.53). Further addition of D-dimer and BMI to this model decreased the OR to 1.70 (0.98, 2.93). Low TFPI did not demonstrate greater than additive interaction with other VTE risk factors...
- Association of coagulation-related and inflammation-related genes and factor VIIc levels with stroke: the Cardiovascular Health StudyN A Zakai
Department of Medicine, University of Vermont, Burlington, VT, USA
J Thromb Haemost 9:267-74. 2011..Thrombosis and inflammation are critical in stroke etiology, but associations of coagulation and inflammation gene variants with stroke, and particularly factor VII levels, are inconclusive...
- Racial differences in venous thromboembolismN A Zakai
Department of Medicine and Pathology, College of Medicine, University of Vermont, Colchester, VT 05446, USA
J Thromb Haemost 9:1877-82. 2011..While differences in VTE by race due to genetic predisposition will probably always be present, understanding the reasons for racial differences in VTE will help providers develop strategies to minimize VTE in all populations...
- Metabolic syndrome, inflammation, and incident heart failure in the elderly: the cardiovascular health studyTakeki Suzuki
Department of Medicine, University of Vermont College of Medicine, Burlington, VT, USA
Circ Heart Fail 1:242-8. 2008..We evaluated whether combining inflammation markers and MetS provided additive information for incident CHF and if incorporating inflammation markers to the MetS definition added prognostic information...
- Correlates of anemia in American blacks and whites: the REGARDS Renal Ancillary StudyNeil A Zakai
Department of Medicine, University of Vermont, Burlington, VT, USA
Am J Epidemiol 169:355-64. 2009..Race differences in anemia prevalence were not explained by the factors studied. Future research into the causes and consequences of anemia in different racial groups is needed...
- American Heart Association's Life's Simple 7 and risk of venous thromboembolism: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) studyNels C Olson
Department of Pathology, University of Vermont College of Medicine, Burlington, VT N C O, M C, N A Z
J Am Heart Assoc 4:e001494. 2015..The metric includes body mass index (BMI), blood pressure, cholesterol, glucose, physical activity (PA), cigarette smoking, and diet. We hypothesized a lower risk of venous thromboembolism (VTE) with favorable Life's Simple 7 scores...
- A prospective study of anemia status, hemoglobin concentration, and mortality in an elderly cohort: the Cardiovascular Health StudyNeil A Zakai
Department of Medicine, University of Vermont College of Medicine and Fletcher Allen Health Care, Burlington, USA
Arch Intern Med 165:2214-20. 2005..Anemia is viewed as a negative prognostic factor in the elderly population; its independent impact on survival is unclear...
- Anemia is associated with the progression of white matter disease in older adults with high blood pressure: the cardiovascular health studyMarco Inzitari
Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Am Geriatr Soc 56:1867-72. 2008..To investigate whether anemia predicts worsening white matter hyperintensities (WMHs) in older community-dwellers...
- Detection of chronic kidney disease with creatinine, cystatin C, and urine albumin-to-creatinine ratio and association with progression to end-stage renal disease and mortalityCarmen A Peralta
Department of Medicine, San Francisco VA Medical Center, San Francisco, California, USA
JAMA 305:1545-52. 2011..A triple-marker approach for chronic kidney disease (CKD) evaluation has not been well studied...
- Measures of Kidney Disease and the Risk of Venous Thromboembolism in the REGARDS (Reasons for Geographic and Racial Differences in Stroke) StudyKatharine L Cheung
Larner College of Medicine, University of Vermont, Burlington, VT Electronic address
Am J Kidney Dis . 2017..Kidney disease has been associated with venous thromboembolism (VTE) risk, but results conflict and there is little information regarding blacks...
- Activated partial thromboplastin time and risk of future venous thromboembolismNeil A Zakai
Department of Medicine, Brown University and Boston University, Providence, RI, USA
Am J Med 121:231-8. 2008..Lower activated partial thromboplastin times are associated with higher levels of some coagulation factors and may represent a procoagulant tendency...
- Validating laboratory results in a national observational cohort study without field centers: the Reasons for Geographic and Racial Differences in Stroke cohortSarah R Gillett
Department of Medicine, University of Vermont College of Medicine, 208 South Park Dr, Colchester, VT 05446, USA
Clin Biochem 47:243-6. 2014..Pre-analytical factors resulting from this study design may affect the results of some laboratory assays. We investigated the impact of REGARDS processing on a variety of analytes...
- Why is my patient anemic?Locke J Bryan
University of Vermont College of Medicine, 111 Colchester Avenue, Smith Room 244, Burlington, VT 05401, USA
Hematol Oncol Clin North Am 26:205-30, vii. 2012..Often the cause of anemia is straightforward; however, the cause can be challenging, requiring a thorough knowledge of both hematology and general medicine...