Young Joo Yi

Summary

Affiliation: University of Missouri
Country: USA

Publications

  1. doi request reprint Interference with the 19S proteasomal regulatory complex subunit PSMD4 on the sperm surface inhibits sperm-zona pellucida penetration during porcine fertilization
    Young Joo Yi
    Division of Animal Sciences, and Department of Obstetrics, Gynecology and Women s Health, University of Missouri Columbia, Columbia, MO, 65211, USA
    Cell Tissue Res 341:325-40. 2010
  2. pmc Identification of the inorganic pyrophosphate metabolizing, ATP substituting pathway in mammalian spermatozoa
    Young Joo Yi
    Division of Animal Sciences, University of Missouri Columbia, Columbia, Missouri, United States of America
    PLoS ONE 7:e34524. 2012
  3. doi request reprint Ubiquitin-activating enzyme (UBA1) is required for sperm capacitation, acrosomal exocytosis and sperm-egg coat penetration during porcine fertilization
    Y J Yi
    Division of Animal Sciences, Gynecology and Women s Health, University of Missouri Columbia, Columbia, MO, USA
    Int J Androl 35:196-210. 2012
  4. doi request reprint Sperm GIRK2-containing K+ inward rectifying channels participate in sperm capacitation and fertilization
    Young Joo Yi
    Division of Animal Sciences, University of Missouri Columbia, Columbia, MO, USA
    Syst Biol Reprod Med 57:296-308. 2011
  5. doi request reprint Inhibition of 19S proteasomal regulatory complex subunit PSMD8 increases polyspermy during porcine fertilization in vitro
    Young Joo Yi
    Division of Animal Sciences, and Department of Obstetrics and Gynecology, University of Missouri, Columbia, MO 65211, USA
    J Reprod Immunol 84:154-63. 2010
  6. ncbi request reprint Ubiquitin C-terminal hydrolase-activity is involved in sperm acrosomal function and anti-polyspermy defense during porcine fertilization
    Young Joo Yi
    Department of Anatomy, University of Missouri Columbia, Missouri 65211, USA
    Biol Reprod 77:780-93. 2007
  7. pmc Sperm proteasomes degrade sperm receptor on the egg zona pellucida during mammalian fertilization
    Shawn W Zimmerman
    Division of Animal Science, and Departments of Obstetrics, Gynecology, and Women s Health, University of Missouri Columbia, Columbia, Missouri, United States of America
    PLoS ONE 6:e17256. 2011
  8. pmc Transgenic pig carrying green fluorescent proteasomes
    Edward L Miles
    Division of Animal Sciences, National Swine Resource and Research Center, and Department of Obstetrics, Gynecology and Women s Health, University of Missouri, Columbia, MO 65211, USA
    Proc Natl Acad Sci U S A 110:6334-9. 2013
  9. ncbi request reprint Mechanism of sperm-zona pellucida penetration during mammalian fertilization: 26S proteasome as a candidate egg coat lysin
    Young Joo Yi
    Division of Animal Sciences, Departments of Obstetrics and Gynecology, University of Missouri Columbia, Columbia, MO 65211, USA
    Soc Reprod Fertil Suppl 63:385-408. 2007
  10. doi request reprint Carbohydrate-mediated binding and induction of acrosomal exocytosis in a boar sperm-somatic cell adhesion model
    Gary F Clark
    Department of Obstetrics, Gynecology, and Women s Health, Division of Reproductive and Perinatal Research, University of Missouri School of Medicine, Columbia, Missouri 65211, USA
    Biol Reprod 83:623-34. 2010

Collaborators

Detail Information

Publications15

  1. doi request reprint Interference with the 19S proteasomal regulatory complex subunit PSMD4 on the sperm surface inhibits sperm-zona pellucida penetration during porcine fertilization
    Young Joo Yi
    Division of Animal Sciences, and Department of Obstetrics, Gynecology and Women s Health, University of Missouri Columbia, Columbia, MO, 65211, USA
    Cell Tissue Res 341:325-40. 2010
    ..The recognition of substrates on the ZP by the 19S proteasomal regulatory complex is essential for the success of porcine/mammalian fertilization in vitro...
  2. pmc Identification of the inorganic pyrophosphate metabolizing, ATP substituting pathway in mammalian spermatozoa
    Young Joo Yi
    Division of Animal Sciences, University of Missouri Columbia, Columbia, Missouri, United States of America
    PLoS ONE 7:e34524. 2012
    ....
  3. doi request reprint Ubiquitin-activating enzyme (UBA1) is required for sperm capacitation, acrosomal exocytosis and sperm-egg coat penetration during porcine fertilization
    Y J Yi
    Division of Animal Sciences, Gynecology and Women s Health, University of Missouri Columbia, Columbia, MO, USA
    Int J Androl 35:196-210. 2012
    ..In summary, it appears that de novo protein ubiquitination involving UBA1 contributes to sperm capacitation and acrosomal function during fertilization...
  4. doi request reprint Sperm GIRK2-containing K+ inward rectifying channels participate in sperm capacitation and fertilization
    Young Joo Yi
    Division of Animal Sciences, University of Missouri Columbia, Columbia, MO, USA
    Syst Biol Reprod Med 57:296-308. 2011
    ..Altogether, studies in two different mammalian species point to a conserved mechanism by which the GIRK2 inward-rectifying K(+) ion channels support sperm function during fertilization...
  5. doi request reprint Inhibition of 19S proteasomal regulatory complex subunit PSMD8 increases polyspermy during porcine fertilization in vitro
    Young Joo Yi
    Division of Animal Sciences, and Department of Obstetrics and Gynecology, University of Missouri, Columbia, MO 65211, USA
    J Reprod Immunol 84:154-63. 2010
    ....
  6. ncbi request reprint Ubiquitin C-terminal hydrolase-activity is involved in sperm acrosomal function and anti-polyspermy defense during porcine fertilization
    Young Joo Yi
    Department of Anatomy, University of Missouri Columbia, Missouri 65211, USA
    Biol Reprod 77:780-93. 2007
    ..We conclude that sperm-acrosomal UCHs are involved in sperm-ZP interactions and antipolyspermy defense. Modulation of UCH activity could facilitate the management of polyspermy during IVF and provide insights into male infertility...
  7. pmc Sperm proteasomes degrade sperm receptor on the egg zona pellucida during mammalian fertilization
    Shawn W Zimmerman
    Division of Animal Science, and Departments of Obstetrics, Gynecology, and Women s Health, University of Missouri Columbia, Columbia, Missouri, United States of America
    PLoS ONE 6:e17256. 2011
    ..Thus, the sperm borne 26S proteasome is a candidate zona lysin in mammals. This new paradigm has implications for contraception and assisted reproductive technologies in humans, as well as animals...
  8. pmc Transgenic pig carrying green fluorescent proteasomes
    Edward L Miles
    Division of Animal Sciences, National Swine Resource and Research Center, and Department of Obstetrics, Gynecology and Women s Health, University of Missouri, Columbia, MO 65211, USA
    Proc Natl Acad Sci U S A 110:6334-9. 2013
    ..This mammal carrying green fluorescent proteasomes will be useful for studies of fertilization and wherever the ubiquitin-proteasome system plays a role in cellular function or pathology...
  9. ncbi request reprint Mechanism of sperm-zona pellucida penetration during mammalian fertilization: 26S proteasome as a candidate egg coat lysin
    Young Joo Yi
    Division of Animal Sciences, Departments of Obstetrics and Gynecology, University of Missouri Columbia, Columbia, MO 65211, USA
    Soc Reprod Fertil Suppl 63:385-408. 2007
    ..Such observations could possibly lead to the development of novel non-hormonal contraceptives, improvement of infertility diagnostics and optimization of assisted reproduction...
  10. doi request reprint Carbohydrate-mediated binding and induction of acrosomal exocytosis in a boar sperm-somatic cell adhesion model
    Gary F Clark
    Department of Obstetrics, Gynecology, and Women s Health, Division of Reproductive and Perinatal Research, University of Missouri School of Medicine, Columbia, Missouri 65211, USA
    Biol Reprod 83:623-34. 2010
    ..This cell adhesion model will be useful for investigating the molecular basis of gamete binding and the induction of acrosomal exocytosis in the pig...
  11. doi request reprint Sperm-surface ATP in boar spermatozoa is required for fertilization: relevance to sperm proteasomal function
    Young Joo Yi
    Division of Animal Sciences, University of Missouri Columbia, Columbia, MO 65211 5300, USA
    Syst Biol Reprod Med 55:85-96. 2009
    ..Altogether, the present data provide an important missing piece of evidence in support of the ssATP-dependent, proteasomal-proteolytic model of sperm-ZP interactions...
  12. doi request reprint Identification and characterization of RING-finger ubiquitin ligase UBR7 in mammalian spermatozoa
    Shawn W Zimmerman
    Division of Animal Sciences, University of Missouri, Columbia, MO, 65211 5300, USA
    Cell Tissue Res 356:261-78. 2014
    ..These data provide the first evidence of ubiquitin ligase activity in mammalian spermatozoa and indicate UBR7 involvement in spermiogenesis...
  13. ncbi request reprint Proteolytic activity of the 26S proteasome is required for the meiotic resumption, germinal vesicle breakdown, and cumulus expansion of porcine cumulus-oocyte complexes matured in vitro
    Young Joo Yi
    Division of Animal Sciences, University of Missouri Columbia, Columbia, MO 65211, USA
    Biol Reprod 78:115-26. 2008
    ..We conclude that proteasomal proteolysis has multiple functions in the progression of oocyte meiosis beyond GV and metaphase I stage, polar body extrusion, and cumulus expansion...
  14. ncbi request reprint Mechanism of extracellular ubiquitination in the mammalian epididymis
    Kathleen M Baska
    Division of Animal Sciences, University of Missouri Columbia, Columbia, Missouri, USA
    J Cell Physiol 215:684-96. 2008
    ..This study provides evidence that the activity of the ubiquitin system is not limited to the intracellular environment, contributing to a greater understanding of the sperm maturation process during epididymal passage...
  15. pmc Regulation of mitochondrial genome inheritance by autophagy and ubiquitin-proteasome system: implications for health, fitness, and fertility
    Won Hee Song
    Division of Animal Science, and Departments of Obstetrics, Gynecology and Women s Health, University of Missouri, Columbia, MO 65211 5300, USA
    Biomed Res Int 2014:981867. 2014
    ..Altogether, the study of sperm mitophagy after fertilization has implications in the timing of evolution and developmental and reproductive biology and in human health, fitness, and management of mitochondrial disease. ..