Yu Xiao Yang

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. pmc Serum glucose and hemoglobin A1C levels at cancer diagnosis and disease outcome
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA Tel Aviv University, Tel Aviv, Israel Electronic address
    Eur J Cancer 59:90-8. 2016
  2. pmc Impact of Metformin on Advanced Pancreatic Cancer Survival: Too Little, Too Late?
    Yu Xiao Yang
    Division of Gastroenterology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Clin Cancer Res 22:1031-3. 2016
  3. pmc The effect of a physician-targeted intervention on metoclopramide prescribing practice
    Yu Xiao Yang
    Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA, USA
    Ther Clin Risk Manag 7:359-65. 2011
  4. pmc Chronic proton pump inihibitor therapy and calcium metabolism
    Yu Xiao Yang
    Division of Gastroenterology, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Curr Gastroenterol Rep 14:473-9. 2012
  5. ncbi request reprint Prevention and treatment of stress ulcers in critically ill patients
    Yu Xiao Yang
    Gastroenterology Division, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Semin Gastrointest Dis 14:11-9. 2003
  6. pmc Serial glycosylated hemoglobin levels and risk of colorectal neoplasia among patients with type 2 diabetes mellitus
    Yu Xiao Yang
    Department of Medicine, Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 722 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Cancer Epidemiol Biomarkers Prev 19:3027-36. 2010
  7. doi request reprint Safety of proton pump inhibitor exposure
    Yu Xiao Yang
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Gastroenterology 139:1115-27. 2010
  8. ncbi request reprint Proton pump inhibitor therapy and osteoporosis
    Yu Xiao Yang
    Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Curr Drug Saf 3:204-9. 2008
  9. doi request reprint Chronic statin therapy and the risk of colorectal cancer
    Yu Xiao Yang
    Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 17:869-76. 2008
  10. ncbi request reprint Chronic proton pump inhibitor therapy and the risk of colorectal cancer
    Yu Xiao Yang
    Division of Gastroenterology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6021, USA
    Gastroenterology 133:748-54. 2007

Collaborators

Detail Information

Publications59

  1. pmc Serum glucose and hemoglobin A1C levels at cancer diagnosis and disease outcome
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA Tel Aviv University, Tel Aviv, Israel Electronic address
    Eur J Cancer 59:90-8. 2016
    ..We aimed to evaluate associations between glucose, hemoglobin A1C (HbA1C), and survival among individuals with diabetes and diabetes associated cancers...
  2. pmc Impact of Metformin on Advanced Pancreatic Cancer Survival: Too Little, Too Late?
    Yu Xiao Yang
    Division of Gastroenterology and Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Clin Cancer Res 22:1031-3. 2016
    ..Future studies may need to consider its role in early-stage pancreatic cancer. See related article by Reni et al., p. 1076...
  3. pmc The effect of a physician-targeted intervention on metoclopramide prescribing practice
    Yu Xiao Yang
    Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA, USA
    Ther Clin Risk Manag 7:359-65. 2011
    ..Metoclopramide use is associated with serious and potentially irreversible neurologic side effects. However, it is often used for questionable or unclear indications in clinical practice...
  4. pmc Chronic proton pump inihibitor therapy and calcium metabolism
    Yu Xiao Yang
    Division of Gastroenterology, The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Curr Gastroenterol Rep 14:473-9. 2012
    ..Second, profound gastric acid suppression may reduce the bioavailability of calcium for intestinal absorption. I will review the published evidence regarding these potential links and discuss their clinical implications...
  5. ncbi request reprint Prevention and treatment of stress ulcers in critically ill patients
    Yu Xiao Yang
    Gastroenterology Division, Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA
    Semin Gastrointest Dis 14:11-9. 2003
    ..More potent acid suppression by proton pump inhibitors may offer additional benefit in the prevention of stress ulcer bleeding...
  6. pmc Serial glycosylated hemoglobin levels and risk of colorectal neoplasia among patients with type 2 diabetes mellitus
    Yu Xiao Yang
    Department of Medicine, Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 722 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Cancer Epidemiol Biomarkers Prev 19:3027-36. 2010
    ..We sought to determine whether glycemic control measured by serial hemoglobin A1c (HbA1c) was associated with the risk of colorectal adenoma...
  7. doi request reprint Safety of proton pump inhibitor exposure
    Yu Xiao Yang
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Gastroenterology 139:1115-27. 2010
    ..We summarize the data available on the putative adverse effects of PPI therapy and propose guidelines for clinicians who prescribe these agents to limit the potential for adverse outcomes in users of these effective therapeutic agents...
  8. ncbi request reprint Proton pump inhibitor therapy and osteoporosis
    Yu Xiao Yang
    Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, and Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Curr Drug Saf 3:204-9. 2008
    ....
  9. doi request reprint Chronic statin therapy and the risk of colorectal cancer
    Yu Xiao Yang
    Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Pharmacoepidemiol Drug Saf 17:869-76. 2008
    ..We sought to clarify whether long-term statin therapy has a chemopreventive effect on the risk of colorectal cancer (CRC) in a large, population-representative cohort...
  10. ncbi request reprint Chronic proton pump inhibitor therapy and the risk of colorectal cancer
    Yu Xiao Yang
    Division of Gastroenterology, University of Pennsylvania, Philadelphia, Pennsylvania 19104 6021, USA
    Gastroenterology 133:748-54. 2007
    ....
  11. ncbi request reprint Long-term proton pump inhibitor therapy and risk of hip fracture
    Yu Xiao Yang
    Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    JAMA 296:2947-53. 2006
    ..Proton pump inhibitors (PPIs) may interfere with calcium absorption through induction of hypochlorhydria but they also may reduce bone resorption through inhibition of osteoclastic vacuolar proton pumps...
  12. ncbi request reprint Insulin therapy and colorectal cancer risk among type 2 diabetes mellitus patients
    Yu Xiao Yang
    Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
    Gastroenterology 127:1044-50. 2004
    ..We aimed to determine whether insulin therapy might increase the risk of colorectal cancer among type 2 diabetes mellitus patients...
  13. ncbi request reprint Women with a prior diagnosis of breast cancer are not at an increased risk for subsequent colorectal cancer
    Radhika Srinivasan
    Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Am J Gastroenterol 100:2759-64. 2005
    ..Earlier studies regarding the risk of colorectal cancer in women with a prior diagnosis of breast cancer yielded conflicting results...
  14. pmc Risk of hip fracture associated with untreated and treated chronic hepatitis B virus infection
    Dana D Byrne
    Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    J Hepatol 61:210-8. 2014
    ..Our objectives were to determine whether untreated or treated CHB-infected persons are at increased risk for hip fracture compared to uninfected persons...
  15. ncbi request reprint Type 2 diabetes mellitus and the risk of colorectal cancer
    Yu Xiao Yang
    Division of Gastroenterology, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Clin Gastroenterol Hepatol 3:587-94. 2005
    ..However, epidemiologic evidence for this association is inconclusive. We conducted a population-based study to clarify this association...
  16. pmc Fibrate/Statin initiation in warfarin users and gastrointestinal bleeding risk
    Hedi Schelleman
    Center for Clinical Epidemiology and Biostatistics and Center for Education and Research on Therapeutics, University of Pennsylvania School of Medicine, Philadelphia, USA
    Am J Med 123:151-7. 2010
    ..To evaluate whether initiation of a fibrate or statin increases the risk of hospitalization for gastrointestinal bleeding in warfarin users...
  17. pmc A Clinical Prediction Model to Assess Risk for Pancreatic Cancer Among Patients With New-onset Diabetes
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA Tel Aviv University, Tel Aviv, Israel
    Gastroenterology . 2016
    ..Screening individuals with new-onset diabetes might therefore allow earlier diagnosis of PDA. We sought to develop and validate a PDA risk prediction model to identify high-risk individuals among those with new-onset diabetes...
  18. pmc Observed association between antidepressant use and pneumonia risk was confounded by comorbidity measures
    Sean Hennessy
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    J Clin Epidemiol 60:911-8. 2007
    ..A prior study suggested that antidepressants might increase the risk of hospitalization for pneumonia in the elderly. This study sought to confirm or refute this hypothesis...
  19. pmc Angiotensin-converting enzyme inhibitor therapy and colorectal cancer risk
    George A Makar
    Affiliations of authors Division of Gastroenterology GAM, Y XY and Center for Clinical Epidemiology and Biostatistics GAM, JHH, Y XY, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
    J Natl Cancer Inst 106:djt374. 2014
    ..Given their widespread use, we sought to determine whether exposure to these agents would have a secondary benefit on CRC incidence...
  20. ncbi request reprint Association between model for end-stage liver disease and spontaneous bacterial peritonitis
    Keith L Obstein
    Department of Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Gastroenterol 102:2732-6. 2007
    ..To determine whether a greater Model for End-Stage Liver Disease (MELD) score is associated with a greater risk of spontaneous bacterial peritonitis (SBP)...
  21. ncbi request reprint Proton-pump inhibitor use and the risk for community-acquired pneumonia
    Monika Sarkar
    University of Pennsylvania, Philadelphia, Pennsylvania 19104 6021, USA
    Ann Intern Med 149:391-8. 2008
    ..Recent studies suggest that proton-pump inhibitors (PPIs) may increase the risk for community-acquired pneumonia (CAP)...
  22. pmc Metformin and survival in pancreatic cancer: a retrospective cohort study
    Allen L Hwang
    From the Division of Gastroenterology, Hospital at the University of Pennsylvania and Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA
    Pancreas 42:1054-9. 2013
    ..Our aim was to determine the effect of metformin exposure on survival in patients with advanced pancreatic adenocarcinoma (PAC)...
  23. doi request reprint Gastroesophageal reflux and sleep events in obstructive sleep apnea
    Yu Xiao Yang
    aDepartment of Medicine, Division of Gastroenterology bDepartment of Medicine, Division of Sleep Medicine cCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Eur J Gastroenterol Hepatol 25:1017-23. 2013
    ..Gastroesophageal reflux disease (GERD) and obstructive sleep apnea (OSA) often coexist. We sought to determine the presence and direction of any association between GERD and sleep events in patients with OSA...
  24. pmc Risk of hip fracture associated with hepatitis C virus infection and hepatitis C/human immunodeficiency virus coinfection
    Vincent Lo Re
    Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Hepatology 56:1688-98. 2012
    ..56; 95% CI: 2.93-4.32; males, 18-39 years: HR, 2.40; 95% CI: 2.02-2.84)...
  25. pmc Insulin therapy and colorectal adenomas in patients with diabetes mellitus
    Patricia Wong
    Division of Gastroenterology, Hospital of the University of Pennsylvania, Philadelphia, USA
    Cancer Epidemiol Biomarkers Prev 21:1833-40. 2012
    ..The aim of this study was to evaluate the association between exogenous insulin therapy and adenoma formation, accounting for duration of therapy and location and stage of the adenoma...
  26. pmc Hip fracture risk in patients with a diagnosis of pernicious anemia
    Nathan A Merriman
    Division of Gastroenterology, Center for Clinical Epidemiology and Biostatistics, Philadelphia, Pennsylvania 19104 6021, USA
    Gastroenterology 138:1330-7. 2010
    ..Pernicious anemia (PA) is characterized by vitamin B-12 deficiency and achlorhydria, both of which have a detrimental effect on bone strength. The principle aim of this study was to determine the risk of hip fracture in patients with PA...
  27. doi request reprint A Risk Prediction Model for Sporadic CRC Based on Routine Lab Results
    Ben Boursi
    Division of Gastroenterology, Perelman School of Medicine at the University of Pennsylvania, 733 Blockley Hall, 423 Guardian Drive, Philadelphia, PA, 19104 6021, USA
    Dig Dis Sci 61:2076-86. 2016
    ..Current risk scores for colorectal cancer (CRC) are based on demographic and behavioral factors and have limited predictive values...
  28. pmc Association of Itraconazole, a Hedgehog Inhibitor, and Bladder Cancer
    Ronac Mamtani
    Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania Electronic address
    J Urol 196:343-8. 2016
    ..Itraconazole, an antifungal, is the only azole known to be a potent Hh pathway antagonist. We evaluated whether itraconazole use is associated with bladder cancer risk or progression...
  29. pmc Prevalence of diagnosed chronic hepatitis B infection among U.S. Medicaid enrollees, 2000-2007
    Dana D Byrne
    Division of Infectious Diseases, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine, University of Pennsylvania, Philadelphia
    Ann Epidemiol 24:418-23. 2014
    ..S. Medicaid programs of California, Florida, New York, Ohio, and Pennsylvania between 2000 and 2007. As part of our analyses, we confirmed the accuracy of CHB diagnoses within the Medicaid database...
  30. ncbi request reprint Risk of colorectal cancer in women with a prior diagnosis of gynecologic malignancy
    Radhika Srinivasan
    Department of Medicine, Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Clin Gastroenterol 41:291-6. 2007
    ..Earlier studies regarding the risk of colorectal cancer (CRC) in women with a prior diagnosis of gynecologic malignancies have revealed conflicting results. We sought to further clarify this association...
  31. pmc No increased risk of myocardial infarction among patients with ulcerative colitis or Crohn's disease
    Mark T Osterman
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Gastroenterol Hepatol 9:875-80. 2011
    ..We aimed to determine the risk of first-time acute MI in patients with ulcerative colitis (UC) or Crohn's disease (CD) compared with patients from general practice...
  32. pmc Findings on serial surveillance colonoscopy in patients with low-risk polyps on initial colonoscopy
    Jocelyne Miller
    Division of Gastroenterology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    J Clin Gastroenterol 44:e46-50. 2010
    ..This study describes the prevalence of adenomatous polyps at serial follow-up exams after a colonoscopy finding 1 to 2 small tubular adenomas...
  33. pmc Parkinson's disease and colorectal cancer risk-A nested case control study
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA, USA Tel Aviv University, Tel Aviv, Israel
    Cancer Epidemiol 43:9-14. 2016
    ..We sought to evaluate the association between Parkinson's disease and CRC...
  34. ncbi request reprint An association between newly diagnosed cutaneous T cell lymphoma and prior impetigo: a nested case-control study
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA
    Arch Dermatol Res 308:661-664. 2016
    ..09, 95 % CI 0.35-3.37). Our results suggest a possible association between SA colonization and CTCL initiation that might serve as an important etiological factor for the disease...
  35. doi request reprint Reappraisal of risk factors for monoclonal gammopathy of undetermined significance
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    Am J Hematol 91:581-4. 2016
    ..Am. J. Hematol. 91:581-584, 2016. © 2016 Wiley Periodicals, Inc. ..
  36. pmc Height as an independent anthropomorphic risk factor for colorectal cancer
    Ben Boursi
    aDepartment of Epidemiology and Biostatistics, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine bDivision of Gastroenterology cDivision of Hematology Medical Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA dThe Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center eTel Aviv University, Tel Aviv, Israel
    Eur J Gastroenterol Hepatol 26:1422-7. 2014
    ..None of those studies adjusted the association for known risk factors, such as diabetes mellitus and chronic exposure to aspirin/NSAIDs. Only two studies evaluated the risk among male individuals...
  37. doi request reprint Pernicious anemia and colorectal cancer risk - A nested case-control study
    Ben Boursi
    Division of Gastroenterology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA Tel Aviv University, Tel Aviv, Israel
    Dig Liver Dis 48:1386-1390. 2016
    ..Hypergastrinemia was shown to stimulate colonic epithelial cell proliferation...
  38. pmc Disentangling the Association between Statins, Cholesterol, and Colorectal Cancer: A Nested Case-Control Study
    Ronac Mamtani
    Division of Hematology Oncology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
    PLoS Med 13:e1002007. 2016
    ..We hypothesized that these findings may be due to systematic bias and examined the independent association of colorectal cancer risk with statin use, serum cholesterol, and change in cholesterol concentration...
  39. pmc Ion channel blockers and glioblastoma risk and outcome: a nested case-control and retrospective cohort studies
    Ben Boursi
    Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Pharmacoepidemiol Drug Saf 25:1179-1185. 2016
    ..We sought to evaluate the association between the use of specific ion channel blockers such as digoxin, amiodarone, diltiazem and verapamil and GBM risk and survival...
  40. doi request reprint Anti-depressant therapy and cancer risk: a nested case-control study
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA The Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur Neuropsychopharmacol 25:1147-57. 2015
    ..Odds ratios (ORs) and 95% CIs were estimated for each anti-depressant class using conditional logistic-regression analysis, adjusted for potential confounders, such as obesity, smoking history and alcohol consumption...
  41. pmc Recurrent antibiotic exposure may promote cancer formation--Another step in understanding the role of the human microbiota?
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA The Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Tel Aviv University, Tel Aviv, Israel
    Eur J Cancer 51:2655-64. 2015
    ..In a recent animal model, tumour susceptibility was transmitted using faecal transplantation. Our aim was to evaluate possible association between antibiotic exposure and cancer risk...
  42. pmc Thyroid dysfunction, thyroid hormone replacement and colorectal cancer risk
    Ben Boursi
    Division of Gastroenterology BB, YXY, Center for Clinical Epidemiology and Biostatistics BB, KH, RM, YXY, Department of Biostatistics and Epidemiology BB, KH, RM, YXY, Division of Hematology Oncology RM, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel BB
    J Natl Cancer Inst 107:djv084. 2015
    ..We sought to determine the risk of developing CRC in patients with thyroid dysfunction, with and without thyroid hormone replacement (THR)...
  43. pmc Digoxin use and the risk for colorectal cancer
    Ben Boursi
    Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA, USA Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, USA Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA The Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Tel Aviv University, Tel Aviv, Israel
    Pharmacoepidemiol Drug Saf 23:1147-53. 2014
    ..Cardiac glycosides affect several pathways central for tumor formation. We sought to evaluate the association between digoxin use and colorectal cancer (CRC) risk...
  44. pmc The effect of past antibiotic exposure on diabetes risk
    Ben Boursi
    Perelman School of Medicine at the University of PennsylvaniaPhiladelphia, Pennsylvania, USAThe Integrated Cancer Prevention CenterTel Aviv Sourasky Medical Center, Tel Aviv, IsraelTel Aviv UniversityTel Aviv, Israel Perelman School of Medicine at the University of PennsylvaniaPhiladelphia, Pennsylvania, USAThe Integrated Cancer Prevention CenterTel Aviv Sourasky Medical Center, Tel Aviv, IsraelTel Aviv UniversityTel Aviv, Israel Perelman School of Medicine at the University of PennsylvaniaPhiladelphia, Pennsylvania, USAThe Integrated Cancer Prevention CenterTel Aviv Sourasky Medical Center, Tel Aviv, IsraelTel Aviv UniversityTel Aviv, Israel
    Eur J Endocrinol 172:639-48. 2015
    ..Antibiotic therapy can alter the microbiota, and is commonly used in western countries. We sought to evaluate whether past antibiotic exposure increases diabetes risk...
  45. doi request reprint Impact of antibiotic exposure on the risk of colorectal cancer
    Ben Boursi
    Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA The Integrated Cancer Prevention Center, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel Tel Aviv University, Tel Aviv, Israel
    Pharmacoepidemiol Drug Saf 24:534-42. 2015
    ..Our aim was to evaluate the association between the type and cumulative duration of antibiotic exposure and CRC risk...
  46. pmc Diagnosis of pernicious anemia and the risk of pancreatic cancer
    Pari Shah
    From the Department of Medicine, Gastroenterology and Nutrition Service, Memorial Sloan Kettering Cancer Center, New York, NY and Division of Gastroenterology, Department of Medicine, and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
    Pancreas 43:422-6. 2014
    ..Pernicious anemia (PA) is a clinical condition characterized by chronic hypergastrinemia. The aim of this study was to determine if PA is a risk factor for pancreatic cancer...
  47. ncbi request reprint Videofluoroscopic studies of swallowing dysfunction and the relative risk of pneumonia
    Lana Pikus
    Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce St, Philadelphia 19104, USA
    AJR Am J Roentgenol 180:1613-6. 2003
    ..The purpose of our investigation was to determine the relationship between the degree of swallowing dysfunction observed on barium studies and the likelihood of developing pneumonia in a large series of patients...
  48. ncbi request reprint Cholecystectomy and the risk of colorectal cancer
    Theresa Shao
    Division of Gastroenterology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Am J Gastroenterol 100:1813-20. 2005
    ..However, the clinical evidence and the underlying mechanism for this association are still inconclusive. We conducted a population-based study to further clarify this association...
  49. doi request reprint Type 2 diabetes mellitus and survival in pancreatic adenocarcinoma: a retrospective cohort study
    Allen Hwang
    Department of Gastroenterology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA
    Cancer 119:404-10. 2013
    ..Our aim was to determine the effect of varying durations of pre-existing T2DM on survival in patients with PAC...
  50. ncbi request reprint Incidence and prevalence of abnormal liver associated enzymes in patients with atrial fibrillation in a routine clinical care population
    George A Makar
    Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Pharmacoepidemiol Drug Saf 17:43-51. 2008
    ..The aim of this study was to estimate the prevalence and incidence of alanine aminotransferase (ALT) elevations in a cohort with AF...
  51. pmc Risk of community-acquired pneumonia in patients with a diagnosis of pernicious anemia: a population-based retrospective cohort study
    Christopher V Almario
    aCedars Sinai Center for Outcomes Research and Education CS CORE bDepartment of Medicine, Division of Gastroenterology, Cedars Sinai Medical Center cDepartment of Medicine, Division of Digestive Diseases, University of California Los Angeles, Los Angeles, California dDepartment of Medicine, Division of Gastroenterology, Hospital of the University of Pennsylvania eDepartment of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Eur J Gastroenterol Hepatol 27:1259-64. 2015
    ..We conducted a population-based study to determine whether individuals with PA are at an increased risk for community-acquired pneumonia (CAP)...
  52. pmc Detection of circulating pancreas epithelial cells in patients with pancreatic cystic lesions
    Andrew D Rhim
    Division of Gastroenterology, Department of Internal Medicine, Pancreatic Cancer Center, University of Michigan Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan Gastroenterology Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Electronic address
    Gastroenterology 146:647-51. 2014
    ..These findings indicate that cancer cells are present in the circulation of patients before tumors are detected, which might be used in risk assessment...
  53. ncbi request reprint Corticosteroids in Crohn's disease
    Yu Xiao Yang
    Department of Medicine, Hospital of the University of Pennsylvania, University of Pennsylvania School of Medicine, Philadelphia 19104 4283, USA
    Am J Gastroenterol 97:803-23. 2002
    ..Alternative classes of medical therapy for Crohn's disease, including modified corticosteroids and a group of new biological therapies, have proven to be efficacious in the management of active and/or quiescent Crohn's disease...
  54. doi request reprint Peptide Receptor Radionuclide Therapy-Induced Hepatotoxicity in Patients With Metastatic Neuroendocrine Tumors
    Brian P Riff
    From the Division of Gastroenterology, Department of Radiology, and Division of Medical Oncology, Hospital of the University of Pennsylvania, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA Clinic of Radiology and Nuclear Medicine, Division of Nuclear Medicine, University Basel Hospital, Basel, Switzerland
    Clin Nucl Med 40:845-50. 2015
    ..Renal dysfunction, anemia, and thrombocytopenia are well-described treatment-related toxicities. However, hepatotoxicity is not well recognized...
  55. pmc Proton pump inhibitors on pancreatic cancer risk and survival
    Malcolm D Kearns
    Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA Electronic address
    Cancer Epidemiol 46:80-84. 2017
    ..Proton pump inhibitor (PPI) therapy is known to cause hypergastrinemia. We sought to determine the association between PPI therapy and the risk of developing pancreatic cancer as well as survival following pancreatic cancer diagnosis...
  56. ncbi request reprint Association between proton pump inhibitor use and spontaneous bacterial peritonitis
    Mical S Campbell
    Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA
    Dig Dis Sci 53:394-8. 2008
    ..22 (95% confidence interval: 0.52-2.87) and 1.05 (0.43-2.57), respectively. In conclusion, we did not find a positive association between PPI use and spontaneous bacterial peritonitis...
  57. pmc Hypochlorhydria and achlorhydria are associated with false-positive secretin stimulation testing for Zollinger-Ellison syndrome
    Pari Shah
    Division of Gastroenterology and Nutrition, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Pancreas 42:932-6. 2013
    ..Case series have documented false-positive SST in patients with achlorhydria. This study reviews our experience with SST in hypochlorhydric and achlorhydric patients...
  58. pmc Risks and benefits of menopausal hormone therapy in postmenopausal Chinese women
    Irene H Su
    University of California, San Diego, Department of Reproductive Medicine, La Jolla, CA, USA
    Menopause 19:931-41. 2012
    ..The aim of this study was to assess risks and benefits of conjugated equine estrogens (CEE) and medroxyprogesterone acetate (MPA) in postmenopausal Chinese women...
  59. ncbi request reprint Barrett's esophagus in 2008: an update
    Richard K Wood
    Division of Gastroenterology, Department of Medicine and Center for Clinical Epidemiology and Biostatistics University of Pennsylvania School of Medicine, Pennsylvania 19104 6021, USA
    Keio J Med 57:132-8. 2008
    ..The advent of various endoscopic ablative therapies has provided a promising alternative to surgery for Barrett's patients with high grade dysplasia (HGD)...