Hongmei Yang

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Statistical estimation & inference of cell counts from ELISPOT limiting dilution assays
    Hongmei Yang
    Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Biopharm Stat 23:921-36. 2013
  2. pmc B cell responses to H5 influenza HA in human subjects vaccinated with a drifted variant
    Jane Baer
    David H Smith Center for Vaccine Biology and Immunology, Aab Institute for Biomedical Sciences, Department of Microbiology and Immunology, Rochester, NY, USA
    Vaccine 28:907-15. 2010
  3. pmc High-resolution temporal response patterns to influenza vaccine reveal a distinct human plasma cell gene signature
    Alicia D Henn
    Department of Medicine, Division of Nephrology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Sci Rep 3:2327. 2013
  4. pmc Increase in IFNγ(-)IL-2(+) cells in recent human CD4 T cell responses to 2009 pandemic H1N1 influenza
    Jason M Weaver
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 8:e57275. 2013
  5. pmc Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization
    Aarthi Sundararajan
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 7:e34377. 2012
  6. pmc B cell response and hemagglutinin stalk-reactive antibody production in different age cohorts following 2009 H1N1 influenza virus vaccination
    Mark Y Sangster
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Clin Vaccine Immunol 20:867-76. 2013
  7. pmc CD4+ T-cell expansion predicts neutralizing antibody responses to monovalent, inactivated 2009 pandemic influenza A(H1N1) virus subtype H1N1 vaccine
    Jennifer L Nayak
    Department of Pediatrics, Department of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Infect Dis 207:297-305. 2013
  8. pmc Developmentally determined reduction in CD31 during gestation is associated with CD8+ T cell effector differentiation in preterm infants
    Kristin M Scheible
    University of Rochester, Department of Pediatrics, 601 Elmwood Avenue, Rochester, NY 14642, United States Electronic address
    Clin Immunol 161:65-74. 2015
  9. pmc Hearing function in patients living with HIV/AIDS
    Amneris E Luque
    1Infectious Diseases Division, Department of Medicine, 2Department of Otolaryngology, 3Center for Navigation and Communication Sciences, and 4Center for Integrative Bioinformatics and Experimental Mathematics, Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Ear Hear 35:e282-90. 2014
  10. pmc Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM
    Tâm D Quách
    Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Immunol 186:4640-8. 2011

Collaborators

Detail Information

Publications11

  1. pmc Statistical estimation & inference of cell counts from ELISPOT limiting dilution assays
    Hongmei Yang
    Department of Biostatistics and Computational Biology, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Biopharm Stat 23:921-36. 2013
    ..Thus, the t -test or the Wilcoxon Rank Sum test can be applied to detect group differences. These methods are compared through simulations and application to real data. ..
  2. pmc B cell responses to H5 influenza HA in human subjects vaccinated with a drifted variant
    Jane Baer
    David H Smith Center for Vaccine Biology and Immunology, Aab Institute for Biomedical Sciences, Department of Microbiology and Immunology, Rochester, NY, USA
    Vaccine 28:907-15. 2010
    ..These observations suggest prior vaccination against H5 influenza HA induces cellular immune responses that cross-react among drifted variants, without precluding a response to new, or existing HA strains...
  3. pmc High-resolution temporal response patterns to influenza vaccine reveal a distinct human plasma cell gene signature
    Alicia D Henn
    Department of Medicine, Division of Nephrology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Sci Rep 3:2327. 2013
    ..With robust statistical methods, time-varying response characteristics of individual subjects were effectively captured along with a shared plasma cell gene signature. ..
  4. pmc Increase in IFNγ(-)IL-2(+) cells in recent human CD4 T cell responses to 2009 pandemic H1N1 influenza
    Jason M Weaver
    David H Smith Center for Vaccine Biology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 8:e57275. 2013
    ....
  5. pmc Host differences in influenza-specific CD4 T cell and B cell responses are modulated by viral strain and route of immunization
    Aarthi Sundararajan
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
    PLoS ONE 7:e34377. 2012
    ..Our findings emphasize the importance of immunization strategy for demonstrating inherent host differences in CD4 T cell and B cell responses...
  6. pmc B cell response and hemagglutinin stalk-reactive antibody production in different age cohorts following 2009 H1N1 influenza virus vaccination
    Mark Y Sangster
    David H Smith Center for Vaccine Biology and Immunology, Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, USA
    Clin Vaccine Immunol 20:867-76. 2013
    ..They also emphasize the need to clarify how the level of circulating stalk-reactive Abs relates to resistance to influenza...
  7. pmc CD4+ T-cell expansion predicts neutralizing antibody responses to monovalent, inactivated 2009 pandemic influenza A(H1N1) virus subtype H1N1 vaccine
    Jennifer L Nayak
    Department of Pediatrics, Department of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, NY 14642, USA
    J Infect Dis 207:297-305. 2013
    ....
  8. pmc Developmentally determined reduction in CD31 during gestation is associated with CD8+ T cell effector differentiation in preterm infants
    Kristin M Scheible
    University of Rochester, Department of Pediatrics, 601 Elmwood Avenue, Rochester, NY 14642, United States Electronic address
    Clin Immunol 161:65-74. 2015
    ....
  9. pmc Hearing function in patients living with HIV/AIDS
    Amneris E Luque
    1Infectious Diseases Division, Department of Medicine, 2Department of Otolaryngology, 3Center for Navigation and Communication Sciences, and 4Center for Integrative Bioinformatics and Experimental Mathematics, Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    Ear Hear 35:e282-90. 2014
    ....
  10. pmc Anergic responses characterize a large fraction of human autoreactive naive B cells expressing low levels of surface IgM
    Tâm D Quách
    Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    J Immunol 186:4640-8. 2011
    ....
  11. pmc Frequencies of human influenza-specific antibody secreting cells or plasmablasts post vaccination from fresh and frozen peripheral blood mononuclear cells
    Shuya Y Kyu
    Division of Pulmonary and Critical Care Medicine, NY 14642, USA
    J Immunol Methods 340:42-7. 2009
    ..43, 0.28, 0.28 respectively). These results demonstrate feasibility of testing whether antigen-specific ASC from frozen PBMC are an early biomarker of long-term antibody responses in multi-center vaccine trials...