Chia Yen Wu

Summary

Affiliation: University of Delaware
Country: USA

Publications

  1. pmc Identification of the phosphorylation sites in the survival motor neuron protein by protein kinase A
    Chia Yen Wu
    Department of Biological Sciences, University of Delaware, Newark, DE, USA
    Biochim Biophys Acta 1814:1134-9. 2011
  2. pmc Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent
    Chia Yen Wu
    Nemours Biomedical Research, Alfred I, duPont Hospital for Children, Wilmington, DE, USA
    BMC Cell Biol 10:40. 2009
  3. pmc Efficient differentiation of mouse embryonic stem cells into motor neurons
    Chia Yen Wu
    Nemours Biomedical Research, Alfred I duPont Hospital for Children, USA
    J Vis Exp . 2012
  4. pmc Proteomic assessment of a cell model of spinal muscular atrophy
    Chia Yen Wu
    Department of Biological Science, University of Delaware, Newark, DE, USA
    BMC Neurosci 12:25. 2011

Detail Information

Publications4

  1. pmc Identification of the phosphorylation sites in the survival motor neuron protein by protein kinase A
    Chia Yen Wu
    Department of Biological Sciences, University of Delaware, Newark, DE, USA
    Biochim Biophys Acta 1814:1134-9. 2011
    ..Mutagenesis of this subset of PKA-phosphorylated sites in SMN affects association of SMN with Gemin2 and Gemin8. This result indicates that phosphorylation of SMN by PKA may play a role in regulation of the in vivo function of SMN...
  2. pmc Increased susceptibility of spinal muscular atrophy fibroblasts to camptothecin is p53-independent
    Chia Yen Wu
    Nemours Biomedical Research, Alfred I, duPont Hospital for Children, Wilmington, DE, USA
    BMC Cell Biol 10:40. 2009
    ..Here, we examine the potential mechanism of camptothecin sensitivity in SMA fibroblasts...
  3. pmc Efficient differentiation of mouse embryonic stem cells into motor neurons
    Chia Yen Wu
    Nemours Biomedical Research, Alfred I duPont Hospital for Children, USA
    J Vis Exp . 2012
    ..Our two-step differentiation protocol provides an efficient way to differentiate mES cells into spinal motor neurons...
  4. pmc Proteomic assessment of a cell model of spinal muscular atrophy
    Chia Yen Wu
    Department of Biological Science, University of Delaware, Newark, DE, USA
    BMC Neurosci 12:25. 2011
    ..Proteomic and western blot analyses were used to probe protein expression alterations in this cell-culture model of SMA that could be relevant to the disease...