Affiliation: University of Hawaii
- Are depressive symptoms a risk factor for mortality in elderly Japanese American men?: the Honolulu-Asia Aging StudyJunji Takeshita
The Honolulu Asia Aging Study, Kuakini Medical Center, 4th Floor, 1356 Lusitana Street, Honolulu, HI 96813, USA
Am J Psychiatry 159:1127-32. 2002..This study determined the influence of depressive symptoms on subsequent mortality of all causes...
- Cerebrovascular pathology and dementia in autopsied Honolulu-Asia Aging Study participantsLon White
Kuakini Medical Center, 846 S Hotel Street, Honolulu, HI 96813, USA
Ann N Y Acad Sci 977:9-23. 2002..The cerebrovascular lesion type most essentially and inclusively related to dementia was multiple microinfarction...
- The effect of social engagement on incident dementia: the Honolulu-Asia Aging StudyJane S Saczynski
Laboratory of Epidemiology, Demography and Biometry, National Institute on Aging, Bethesda, MD 20892 9205, USA
Am J Epidemiol 163:433-40. 2006..12, 3.13). Although low social engagement in late life is associated with risk of dementia, levels of late-life social engagement may already have been modified by the dementing process and may be associated with prodromal dementia...
- White matter lesions on brain magnetic resonance imaging scan and 5-year cognitive decline: the Honolulu-Asia aging studyMichiko Inaba
Department of Geriatric Medicine, John A Hartford Center of Excellence in Geriatrics, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA
J Am Geriatr Soc 59:1484-9. 2011..To study white matter lesions (WMLs) and 5-year cognitive decline in elderly Japanese-American men...
- Recent clinical-pathologic research on the causes of dementia in late life: update from the Honolulu-Asia Aging StudyLon White
Honolulu Asia Aging Study, Kuakini Medical Center, Honolulu, HI, USA
J Geriatr Psychiatry Neurol 18:224-7. 2005..The results suggest that clinical diagnosis of dementia made during life may fail to reflect the pathogenic complexity of this condition in very elderly persons...
- Brain lesions at autopsy in older Japanese-American men as related to cognitive impairment and dementia in the final years of life: a summary report from the Honolulu-Asia aging studyLon White
Pacific Health Research Institute and Kuakini Medical System, PHRI Bishop Street Tower, 700 Bishop Street, Suite 900, Honolulu, Hawaii 96813, USA
J Alzheimers Dis 18:713-25. 2009..6% and co-dominant lesions (most often Alzheimer and microvascular) in 14.2%. These or one or more of the other lesion types were observed in 87.9% of the demented or definitely impaired decedents...
- Relevance of cardiovascular risk factors and ischemic cerebrovascular disease to the pathogenesis of Alzheimer disease: a review of accrued findings from the Honolulu-Asia Aging StudyLon White
Pacific Health Research Institute and Kuakini Medical Center, 846 S Hotel Street, Honolulu, HI 96813, USA
Alzheimer Dis Assoc Disord 20:S79-83. 2006
- MRI volumetric analysis techniques, including hippocampus extraction, based on data from the Honolulu Asia Aging Study (HAAS)Sajung Yun
Pacific Health Research Institute, John A Burns School of Medicine, Kuakni Medical Center, Honolulu, Hawaii, USA
Ethn Dis 20:S1-104-6. 2010..The purpose of this study is to develop and apply methods for volumetric analyses of magnetic resonance imaging (MRI) data for future comparisons with autopsy findings from the same subjects...
- Performance on the CERAD neuropsychology battery of two samples of Japanese-American elders: norms for persons with and without dementiaGerda G Fillenbaum
Center for the Study of Aging and Human Development, Box 3003, Duke University Medical Center, Durham, NC 27710, USA
J Int Neuropsychol Soc 11:192-201. 2005..This battery is useful for comparative epidemiological studies of dementia in minority populations...
- Dementia screening: can a second administration reduce the number of false positives?Daryl Fujii
Hawaii State Hospital, Kaneohe, Hawaii 96744, USA
Am J Geriatr Psychiatry 11:462-5. 2003..Of particular interest is reducing false positives that may generate an unnecessary referral for a dementia work-up...
- The relation between apolipoprotein A-I and dementia: the Honolulu-Asia aging studyJane S Saczynski
Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, Bethesda, MD 20892, USA
Am J Epidemiol 165:985-92. 2007..These results raise the possibility that different lipoprotein components of cholesterol may be differentially associated with dementia...
- Exercise and cognitive functionHelen Petrovitch
Lancet Neurol 4:690-1. 2005
- Correlates of hippocampal neuron number in Alzheimer's disease and ischemic vascular dementiaChris Zarow
University of Southern California, Rancho Los Amigos National Rehabilitation Center, Downey, CA 90242, USA
Ann Neurol 57:896-903. 2005..Reductions in magnetic resonance imaging-derived hippocampal volume reflect loss, rather than shrinkage, of CA1 neurons...
- Variability in midlife systolic blood pressure is related to late-life brain white matter lesions: the Honolulu-Asia Aging studyRichard J Havlik
Laboratory of Epidemiology, Demography, and Biometry, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, MD 20892, USA
Stroke 33:26-30. 2002..Besides the associations with advanced age and high blood pressure (BP), variability in systolic BP (SBP) and the resulting changes in blood flow to the deep arteries of the brain may be contributing factors...