Zun Yi Wang

Summary

Affiliation: University of Wisconsin
Country: USA

Publications

  1. ncbi request reprint 5-HT5a receptors in the carotid body chemoreception pathway of rat
    Z Y Wang
    Department of Comparative Biosciences, University of Wisconsin Madison, 53706, USA
    Neurosci Lett 278:9-12. 2000
  2. ncbi request reprint Expression of 5-HT3 receptors in primary sensory neurons of the petrosal ganglion of adult rats
    Zun Yi Wang
    Department of Surgical Sciences, University of Wisconsin Madison, 53706, USA
    Auton Neurosci 95:121-4. 2002
  3. ncbi request reprint Chronic hypoxia-induced morphological and neurochemical changes in the carotid body
    Zun Yi Wang
    Department of Surgical Sciences, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Microsc Res Tech 59:168-77. 2002
  4. pmc Role of mast cells and protease-activated receptor-2 in cyclooxygenase-2 expression in urothelial cells
    Zun Yi Wang
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1127-35. 2009
  5. doi request reprint Lack of TRPV1 inhibits cystitis-induced increased mechanical sensitivity in mice
    Zun Yi Wang
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53719, USA
    Pain 139:158-67. 2008
  6. pmc Attenuation of cystitis and pain sensation in mice lacking fatty acid amide hydrolase
    Zun Yi Wang
    Department of Surgical Sciences, University of Wisconsin, Madison, WI, USA
    J Mol Neurosci 55:968-76. 2015
  7. pmc Activation of cannabinoid receptor 2 inhibits experimental cystitis
    Zun Yi Wang
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
    Am J Physiol Regul Integr Comp Physiol 304:R846-53. 2013
  8. ncbi request reprint Nerve growth factor mediates peripheral mechanical hypersensitivity that accompanies experimental cystitis in mice
    Simone Domit Guerios
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Dr, Madison, 53706, USA
    Neurosci Lett 392:193-7. 2006
  9. ncbi request reprint Estrogen-induced proliferation of urothelial cells is modulated by nerve growth factor
    Jian Teng
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
    Am J Physiol Renal Physiol 282:F1075-83. 2002
  10. ncbi request reprint Acute acrolein-induced cystitis in mice
    Dale E Bjorling
    Department of Surgical Sciences, School of Veterinary, University of Wisconsin, Madison, WI 53706, USA
    BJU Int 99:1523-9. 2007

Collaborators

Detail Information

Publications23

  1. ncbi request reprint 5-HT5a receptors in the carotid body chemoreception pathway of rat
    Z Y Wang
    Department of Comparative Biosciences, University of Wisconsin Madison, 53706, USA
    Neurosci Lett 278:9-12. 2000
    ..The present study provides direct evidence that 5-HT5a receptors are expressed in the CB, PG and SCG, which all likely play fundamental roles in arterial chemoreception...
  2. ncbi request reprint Expression of 5-HT3 receptors in primary sensory neurons of the petrosal ganglion of adult rats
    Zun Yi Wang
    Department of Surgical Sciences, University of Wisconsin Madison, 53706, USA
    Auton Neurosci 95:121-4. 2002
    ..As many TH-positive neurons in PG innervate type I cells in the carotid body, the coexistence of 5-HT3 receptor and TH in some neurons suggests that this receptor may play a role in carotid body chemoreception...
  3. ncbi request reprint Chronic hypoxia-induced morphological and neurochemical changes in the carotid body
    Zun Yi Wang
    Department of Surgical Sciences, University of Wisconsin Madison, Madison, Wisconsin 53706, USA
    Microsc Res Tech 59:168-77. 2002
    ..During CH the sensitivity of the CB chemoreceptors to hypoxia is increased but the mechanisms by which the many CH-induced structural and neurochemical changes affect the sensitivity of CB to hypoxia remains to be established...
  4. pmc Role of mast cells and protease-activated receptor-2 in cyclooxygenase-2 expression in urothelial cells
    Zun Yi Wang
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, Wisconsin 53719, USA
    Am J Physiol Regul Integr Comp Physiol 297:R1127-35. 2009
    ..These data indicate that there are functional interactions among mast cells, PAR-2 activation, and increased expression of COX-2 in bladder inflammation...
  5. doi request reprint Lack of TRPV1 inhibits cystitis-induced increased mechanical sensitivity in mice
    Zun Yi Wang
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53719, USA
    Pain 139:158-67. 2008
    ..Also, TRPV1 participates in development of visceral pain, as reflected by referred increased mechanosensitivity in peripheral tissues in the presence of visceral inflammation...
  6. pmc Attenuation of cystitis and pain sensation in mice lacking fatty acid amide hydrolase
    Zun Yi Wang
    Department of Surgical Sciences, University of Wisconsin, Madison, WI, USA
    J Mol Neurosci 55:968-76. 2015
    ..Therefore, FAAH could be a therapeutic target to treat clinical symptoms of painful inflammatory bladder diseases. ..
  7. pmc Activation of cannabinoid receptor 2 inhibits experimental cystitis
    Zun Yi Wang
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, Madison, WI 53706, USA
    Am J Physiol Regul Integr Comp Physiol 304:R846-53. 2013
    ..The results of the current study indicate that CB2 is a potential therapeutic target for treatment of bladder inflammation and pain in patients...
  8. ncbi request reprint Nerve growth factor mediates peripheral mechanical hypersensitivity that accompanies experimental cystitis in mice
    Simone Domit Guerios
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, 2015 Linden Dr, Madison, 53706, USA
    Neurosci Lett 392:193-7. 2006
    ..This model of visceral pain causes increased sensitivity to peripheral application of mechanical stimuli. This effect is at least partially mediated by NGF, and the bladder may be the source of NGF in this process...
  9. ncbi request reprint Estrogen-induced proliferation of urothelial cells is modulated by nerve growth factor
    Jian Teng
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
    Am J Physiol Renal Physiol 282:F1075-83. 2002
    ..1 microl/ml). These data indicate that the effects of ER activation on HUC proliferation at least partly involve activation of trkA by NGF...
  10. ncbi request reprint Acute acrolein-induced cystitis in mice
    Dale E Bjorling
    Department of Surgical Sciences, School of Veterinary, University of Wisconsin, Madison, WI 53706, USA
    BJU Int 99:1523-9. 2007
    ....
  11. pmc Bacterial cystitis is accompanied by increased peripheral thermal sensitivity in mice
    Dale E Bjorling
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA
    J Urol 179:759-63. 2008
    ..Visceral inflammation and pain associated with chemical cystitis produce increased sensitivity to noxious stimuli in the sacral dermatomes. We determined whether a similar sensitization occurs in response to bacterial cystitis...
  12. pmc Tumor necrosis factor-α induces expression and release of interleukin-6 by human urothelial cells
    Zun Yi Wang
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53719, USA
    Inflamm Res 60:525-32. 2011
    ....
  13. pmc Inhibition of fatty acid amide hydrolase suppresses referred hyperalgesia induced by bladder inflammation
    Fabiola Voznika Merriam
    Department of Surgical Sciences, School of Veterinary Medicine, Medical College of Wisconsin, Milwaukee, WI 53706, USA
    BJU Int 108:1145-9. 2011
    ....
  14. pmc Lidocaine prevents referred hyperalgesia associated with cystitis
    Simone D Guerios
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA
    Neurourol Urodyn 28:455-60. 2009
    ..This study was performed to determine whether intrathecal or intravesical administration of lidocaine prior, or subsequent, to induction of chemical cystitis in rats would block referred mechanical hyperalgesia...
  15. pmc Cannabinoid receptor 2 is increased in acutely and chronically inflamed bladder of rats
    Fabiola Voznika Merriam
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    Neurosci Lett 445:130-4. 2008
    ..CB2 receptors may be a viable target for pharmacological treatment of bladder inflammation and associated pain...
  16. pmc Blockade of NGF and trk receptors inhibits increased peripheral mechanical sensitivity accompanying cystitis in rats
    Simone D Guerios
    Department of Surgical Sciences, School of Veterinary Medicine, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin, USA
    Am J Physiol Regul Integr Comp Physiol 295:R111-22. 2008
    ..These results suggest that the bladder-derived NGF acting via trk receptors at least partially mediates peripheral sensitization to mechanical stimuli associated with acute and subacute acrolein-induced cystitis...
  17. pmc CB1 cannabinoid receptor agonist prevents NGF-induced sensitization of TRPV1 in sensory neurons
    Thomas S McDowell
    Department of Anesthesiology, School of Medicine and Public Health, University of Wisconsin Madison, 600 Highland Avenue, Madison, WI 53792 3272, USA
    Neurosci Lett 551:34-8. 2013
    ..These results support the hypothesis that cannabinoids, acting through CB1 receptors, may produce analgesia in part by preventing NGF-induced sensitization of TRPV1 in afferent nociceptor nerve endings...
  18. ncbi request reprint Ultrastructural basement membrane topography of the bladder epithelium
    George A Abrams
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53711, USA
    Urol Res 31:341-6. 2003
    ..This information provides a rational basis for design of nanostructured biomaterials to produce composite grafts for repair or replacement of segments of the urinary tract...
  19. pmc Models of inflammation of the lower urinary tract
    Dale E Bjorling
    Department of Surgical Sciences, University of Wisconsin Madison, Madison, WI, USA
    Neurourol Urodyn 30:673-82. 2011
    ..Comparative and translational studies are required if the full potential of findings obtained with animal models to improve prevention and treatment of lower urinary tract inflammation in people is to be realized...
  20. ncbi request reprint Postnatal growth of the carotid body
    Zun Yi Wang
    Department of Surgical Sciences, SVM, University of Wisconsin Madison, 2015 Linden Drive, Madison, WI 53706, USA
    Respir Physiol Neurobiol 149:181-90. 2005
    ..Taken together, the CB undergoes significant morphological and functional changes during the postnatal period over at least 1 month. This process can be altered by oxygen concentration in ambient air...
  21. pmc Roles of estrogen receptor alpha and beta in modulating urothelial cell proliferation
    Jian Teng
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, WI 53706, USA
    Endocr Relat Cancer 15:351-64. 2008
    ..Increased expression of ERalpha may contribute to early induction of cyclin D1 and cyclin E during the cell cycle in bladder cancer cells...
  22. pmc The G protein-coupled receptor GPR30 inhibits human urothelial cell proliferation
    Jian Teng
    Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin 53706, USA
    Endocrinology 149:4024-34. 2008
    ..These results suggest that GPR30-mediated inhibition of urothelial cell proliferation is the result of decreased cyclin D1 by down-regulation of activation protein-1 signaling...
  23. ncbi request reprint Enhancement of the antiangiogenic activity of interleukin-12 by peptide targeted delivery of the cytokine to alphavbeta3 integrin
    Erin B Dickerson
    Department of Medical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison, Wisconsin, USA
    Mol Cancer Res 2:663-73. 2004
    ....