Wei Wang

Summary

Affiliation: University of Illinois
Country: USA

Publications

  1. pmc In utero bisphenol A exposure disrupts germ cell nest breakdown and reduces fertility with age in the mouse
    Wei Wang
    Department of Comparative Biosciences, University of Illinois, 2001 S Lincoln Ave, Urbana, IL 61802, USA Electronic address
    Toxicol Appl Pharmacol 276:157-64. 2014
  2. pmc Di (2-ethylhexyl) phthalate inhibits growth of mouse ovarian antral follicles through an oxidative stress pathway
    Wei Wang
    Department of Comparative Biosciences, University of Illinois, 2001 S Lincoln Ave, Urbana, IL 61802, USA
    Toxicol Appl Pharmacol 258:288-95. 2012
  3. pmc Mono-(2-ethylhexyl) phthalate induces oxidative stress and inhibits growth of mouse ovarian antral follicles
    Wei Wang
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Biol Reprod 87:152. 2012
  4. pmc Bisphenol A inhibits cultured mouse ovarian follicle growth partially via the aryl hydrocarbon receptor signaling pathway
    Ayelet Ziv-Gal
    Department of Comparative Biosciences, University of Illinois, Urbana, IL, USA Electronic address
    Reprod Toxicol 42:58-67. 2013
  5. pmc Methoxychlor induces atresia by altering Bcl2 factors and inducing caspase activity in mouse ovarian antral follicles in vitro
    Mallikarjuna S Basavarajappa
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Reprod Toxicol 34:545-51. 2012
  6. pmc Di-n-butyl phthalate disrupts the expression of genes involved in cell cycle and apoptotic pathways in mouse ovarian antral follicles
    Zelieann R Craig
    Department of Comparative Biosciences, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Biol Reprod 88:23. 2013
  7. pmc Mono(2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles
    Patrick R Hannon
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois
    Biol Reprod 92:120. 2015
  8. pmc Di(2-ethylhexyl) phthalate inhibits antral follicle growth, induces atresia, and inhibits steroid hormone production in cultured mouse antral follicles
    Patrick R Hannon
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, 2001 S Lincoln Ave, Urbana, IL 61802, USA Electronic address
    Toxicol Appl Pharmacol 284:42-53. 2015
  9. doi request reprint Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling
    Zelieann R Craig
    Department of Comparative Biosciences, University of Illinois, 2001 S Lincoln Avenue, Urbana, Illinois 61802, USA
    Reproduction 142:633-46. 2011
  10. pmc Methoxychlor inhibits growth and induces atresia through the aryl hydrocarbon receptor pathway in mouse ovarian antral follicles
    Mallikarjuna S Basavarajappa
    Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Reprod Toxicol 34:16-21. 2012

Collaborators

  • Ayelet Ziv-Gal
  • Jackye Peretz
  • Jodi A Flaws
  • Patrick R Hannon
  • Zelieann R Craig
  • Mallikarjuna S Basavarajappa
  • Changqing Zhou
  • Katherine E Brannick
  • Rupesh K Gupta
  • Isabel Hern├índez-Ochoa
  • Bethany N Karman

Detail Information

Publications12

  1. pmc In utero bisphenol A exposure disrupts germ cell nest breakdown and reduces fertility with age in the mouse
    Wei Wang
    Department of Comparative Biosciences, University of Illinois, 2001 S Lincoln Ave, Urbana, IL 61802, USA Electronic address
    Toxicol Appl Pharmacol 276:157-64. 2014
    ..These results indicate that in utero exposure to low doses of BPA during a critical ovarian developmental window interferes with early ovarian development and reduces fertility with age...
  2. pmc Di (2-ethylhexyl) phthalate inhibits growth of mouse ovarian antral follicles through an oxidative stress pathway
    Wei Wang
    Department of Comparative Biosciences, University of Illinois, 2001 S Lincoln Ave, Urbana, IL 61802, USA
    Toxicol Appl Pharmacol 258:288-95. 2012
    ..Collectively, these data suggest that DEHP inhibits follicle growth by inducing production of ROS and by decreasing the expression and activity of SOD1...
  3. pmc Mono-(2-ethylhexyl) phthalate induces oxidative stress and inhibits growth of mouse ovarian antral follicles
    Wei Wang
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois 61802, USA
    Biol Reprod 87:152. 2012
    ..This may lead to decreased expression of cell-cycle regulators and antiapoptotic regulators and increased expression of proapoptotic factors, which then may lead to inhibition of follicle growth...
  4. pmc Bisphenol A inhibits cultured mouse ovarian follicle growth partially via the aryl hydrocarbon receptor signaling pathway
    Ayelet Ziv-Gal
    Department of Comparative Biosciences, University of Illinois, Urbana, IL, USA Electronic address
    Reprod Toxicol 42:58-67. 2013
    ..These data suggest that BPA may inhibit follicle growth partially via the AHR pathway, whereas its effects on estradiol synthesis likely involve other mechanisms. ..
  5. pmc Methoxychlor induces atresia by altering Bcl2 factors and inducing caspase activity in mouse ovarian antral follicles in vitro
    Mallikarjuna S Basavarajappa
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Reprod Toxicol 34:545-51. 2012
    ..At 48-96 h, MXC induced morphological atresia. At 24-96 h, MXC increased caspase activities. These data suggest that MXC may induce atresia by altering Bcl2 factors and inducing caspase activities in antral follicles...
  6. pmc Di-n-butyl phthalate disrupts the expression of genes involved in cell cycle and apoptotic pathways in mouse ovarian antral follicles
    Zelieann R Craig
    Department of Comparative Biosciences, College of Veterinary Medicine, University of Illinois, Urbana, IL 61802, USA
    Biol Reprod 88:23. 2013
    ..These data suggest that DBP targets antral follicles and alters the expression of cell cycle and apoptosis factors, causes cell cycle arrest, decreases E(2), and triggers atresia, depending on dose...
  7. pmc Mono(2-ethylhexyl) phthalate accelerates early folliculogenesis and inhibits steroidogenesis in cultured mouse whole ovaries and antral follicles
    Patrick R Hannon
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, Illinois
    Biol Reprod 92:120. 2015
    ..Collectively, MEHP mediates the effect of DEHP on accelerated folliculogenesis via overactivating PI3K signaling and inhibits steroidogenesis by decreasing steroidogenic enzyme levels. ..
  8. pmc Di(2-ethylhexyl) phthalate inhibits antral follicle growth, induces atresia, and inhibits steroid hormone production in cultured mouse antral follicles
    Patrick R Hannon
    Department of Comparative Biosciences, University of Illinois at Urbana Champaign, 2001 S Lincoln Ave, Urbana, IL 61802, USA Electronic address
    Toxicol Appl Pharmacol 284:42-53. 2015
    ..Collectively, DEHP directly alters antral follicle functionality by inhibiting growth, inducing atresia, and inhibiting steroidogenesis...
  9. doi request reprint Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling
    Zelieann R Craig
    Department of Comparative Biosciences, University of Illinois, 2001 S Lincoln Avenue, Urbana, Illinois 61802, USA
    Reproduction 142:633-46. 2011
    ..g. dichlorodiphenyltrichloroethane and methoxychlor), plasticizers (e.g. bisphenol A and phthalates), dioxins, polychlorinated biphenyls, and polycyclic aromatic hydrocarbons (e.g. benzo[a]pyrene)...
  10. pmc Methoxychlor inhibits growth and induces atresia through the aryl hydrocarbon receptor pathway in mouse ovarian antral follicles
    Mallikarjuna S Basavarajappa
    Comparative Biosciences, University of Illinois at Urbana Champaign, Urbana, IL 61802, USA
    Reprod Toxicol 34:16-21. 2012
    ..Collectively, these data show that MXC may act through the AHR pathway to inhibit follicle growth and induce atresia in antral follicles of the ovary...
  11. pmc Bisphenol A exposure inhibits germ cell nest breakdown by reducing apoptosis in cultured neonatal mouse ovaries
    Changqing Zhou
    Department of Comparative Biosciences, University of Illinois, Urbana, IL 61802, USA Electronic address
    Reprod Toxicol 57:87-99. 2015
    ..Our results indicate that in vitro BPA exposure significantly inhibits germ cell nest breakdown by altering the expression of key ovarian apoptotic genes, but not by interfering with the oxidative stress pathway. ..
  12. pmc The effects of in utero bisphenol A exposure on reproductive capacity in several generations of mice
    Ayelet Ziv-Gal
    Department of Comparative Biosciences, University of Illinois, Urbana, IL, USA Electronic address
    Toxicol Appl Pharmacol 284:354-62. 2015
    ..Collectively, these data suggest that BPA exposure affects reproductive function in female mice and that some effects may be transgenerational in nature...