- Insulin attenuates vascular smooth muscle calcification but increases vascular smooth muscle cell phosphate transportCecilia C Low Wang
Research Service, Denver Veterans Affairs Medical Center, Denver, CO 80220, United States
Atherosclerosis 195:e65-75. 2007..This effect of insulin contrasts with its effect to induce phosphate transport in VSMC...
- Early growth response gene-1 expression in vascular smooth muscle cells effects of insulin and oxidant stressCecilia C Low Wang
Research Service, Denver Veterans Affairs Medical Center, Denver, Colorado
Am J Hypertens 19:366-72. 2006..In this study we examined the effects of insulin and oxidant stress on Egr-1 expression in vascular smooth muscle cells (VSMC), and identified mechanisms for these effects on Egr-1...
- Insulin affects vascular smooth muscle cell phenotype and migration via distinct signaling pathwaysCecilia C Low Wang
Veterans Affairs Research Service, Denver VA Medical Center, Denver, Colorado 80220, USA
Diabetes 52:2562-9. 2003..Thus, with impaired PI 3-kinase signaling and intact MAPK signaling, as seen in insulin resistance, insulin may lose its ability to maintain VSMC quiescence and instead promote VSMC migration...
- Molecular mechanisms of insulin resistance that impact cardiovascular biologyCecilia C Low Wang
Research Service of the Denver Veterans Affairs Medical Center, Denver, CO, USA
Diabetes 53:2735-40. 2004..Here we discuss some of the effects of insulin resistance and mechanisms of potentially detrimental influence of hyperinsulinemia in the presence of metabolic insulin resistance...