Affiliation: University of Chicago
- Autism as a paradigmatic complex genetic disorderJeremy Veenstra-Vanderweele
Departments of Psychiatry, The University of Chicago, Illinois 60637, USA
Annu Rev Genomics Hum Genet 5:379-405. 2004..However, it is essential that the restricted interests of patients with autism not be reflected in overly restrictive genetic approaches if we are to better understand the genetics of autism in the most expeditious and thorough manner...
- Transmission disequilibrium studies of the serotonin 5-HT2A receptor gene (HTR2A) in autismJeremy Veenstra-Vanderweele
Laboratory of Developmental Neuroscience, Child and Adolescent Psychiatry, Department of Psychiatry, University of Chicago, Chicago, Illinois 60637, USA
Am J Med Genet 114:277-83. 2002..No evidence was found for unequal transmission of haplotypes; however, power analysis reveals low power to detect a parent-of-origin effect in this sample size...
- Genome-wide association study identifies ITGB3 as a QTL for whole blood serotoninLauren A Weiss
Department of Human Genetics, The University of Chicago, Chicago, IL 60637, USA
Eur J Hum Genet 12:949-54. 2004..8 x 10(-5)). This variant explained the evidence for linkage in this region when included as a covariate in the linkage analysis (change in LOD from 1.87 to 0.16), indicating that ITGB3 may be an important serotonin QTL...
- Mutation screening and transmission disequilibrium study of ATP10C in autismSoo Jeong Kim
Laboratory of Developmental Neuroscience, Child and Adolescent Psychiatry, Department of Psychiatry MC3077, University of Chicago, Chicago, Illinois 60637, USA
Am J Med Genet 114:137-43. 2002....
- Knockout mouse points to second form of tryptophan hydroxylaseJeremy Veenstra-Vanderweele
Department of Psychiatry, The University of Chicago, Chicago, Illinois 60637, USA
Mol Interv 3:72-5, 50. 2003..Veenstra-Vanderweele and Cook discuss the ramifications of these findings and what they might mean for designing drugs that target the expression and activity of TPH in differing tissues...
- Genetics of childhood disorders: XLVI. Autism, part 5: genetics of autismJeremy Veenstra-Vanderweele
Department of Psychiatry, University of Chicago, USA
J Am Acad Child Adolesc Psychiatry 42:116-8. 2003
- Molecular genetics of the platelet serotonin system in first-degree relatives of patients with autismSarah Cross
Pritzker School of Medicine, University of Chicago, Chicago, IL, USA
Neuropsychopharmacology 33:353-60. 2008..046). These initial studies of indices of the 5-HT system with several single-nucleotide polymorphisms at loci in this system generate hypotheses for testing in other samples...