- GPCR endocytosis confers uniformity in responses to chemically distinct ligandsNikoleta G Tsvetanova
Mol Pharmacol . 2016..Based on these findings, we propose that GPCR signaling from endosomes functions as a biological noise filter to enhance reliability of cognate ligand detection...
- The secretory pathway in control of endoplasmic reticulum homeostasisNikoleta G Tsvetanova
Department of Psychiatry, University of California at San Francisco, San Francisco, CA, USA
Small Gtpases 4:28-33. 2013..Other small GTPases of the Ypt family also interacted with the unprocessed RNA. Here we speculate about the possible mechanism behind this novel secretory pathway-dependent regulation of endoplasmic reticulum homeostasis...
- The yeast Rab GTPase Ypt1 modulates unfolded protein response dynamics by regulating the stability of HAC1 RNANikoleta G Tsvetanova
Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA
PLoS Genet 8:e1002862. 2012..Our findings establish that Ypt1 contributes to regulation of UPR signaling dynamics by promoting the decay of HAC1 RNA, suggesting a potential regulatory mechanism for linking vesicle trafficking to the UPR and ER homeostasis...
- Proteome-wide search reveals unexpected RNA-binding proteins in Saccharomyces cerevisiaeNikoleta G Tsvetanova
Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
PLoS ONE 5:. 2010..Our results suggest that many more RBPs still remain to be identified and provide a set of candidates for further investigation...