Kathleen C Torkko

Summary

Affiliation: University of Colorado Denver
Country: USA

Publications

  1. doi request reprint Prostate Biopsy Markers of Inflammation are Associated with Risk of Clinical Progression of Benign Prostatic Hyperplasia: Findings from the MTOPS Study
    Kathleen C Torkko
    Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado Electronic address
    J Urol 194:454-61. 2015
  2. doi request reprint VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men
    Kathleen C Torkko
    Department of Pathology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado 80045, USA
    Clin Cancer Res 14:3223-9. 2008
  3. ncbi request reprint B7-H4 (DD-O110) is overexpressed in high risk uterine endometrioid adenocarcinomas and inversely correlated with tumor T-cell infiltration
    Takashi Miyatake
    Department of Pathology, University of Colorado at Denver and Health Sciences Center, 12800 E 19th Ave Aurora, CO 80010, USA
    Gynecol Oncol 106:119-27. 2007
  4. doi request reprint ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease
    Meenakshi Singh
    Department of Pathology, University of Colorado Health Sciences Center, Aurora, CO 80045, USA
    Mod Pathol 21:912-23. 2008
  5. doi request reprint Detection of B7-H4 and p53 in pancreatic cancer: potential role as a cytological diagnostic adjunct
    Nida S Awadallah
    Division of Gastroenterology, Department of Internal Medicine, University of Colorado at Denver and Health Science Center, Aurora, CO 80045, USA
    Pancreas 36:200-6. 2008
  6. pmc Pseudolumen size and perimeter in prostate cancer: correlation with patient outcome
    Kenneth A Iczkowski
    Department of Pathology, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    Prostate Cancer 2011:693853. 2011
  7. ncbi request reprint B7-h4 expression in a range of breast pathology: correlation with tumor T-cell infiltration
    Kimberly C Mugler
    Department of Pathology, University of Colorado at Denver and Health Sciences Center, 12800 East 19th Avenue, Aurora, CO 80045, USA
    Appl Immunohistochem Mol Morphol 15:363-70. 2007
  8. doi request reprint Preoperative prediction of unifocal, unilateral, margin-negative, and small volume prostate cancer
    Kenneth A Iczkowski
    Department of Pathology, University of Colorado Health Science Center, Denver, Colorado 80045, USA
    Urology 71:1166-71. 2008
  9. pmc Reduced expression of GDF-15 is associated with atrophic inflammatory lesions of the prostate
    James R Lambert
    Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado
    Prostate 75:255-65. 2015
  10. pmc Anterior tumors of the prostate: diagnosis and significance
    Priya N Werahera
    University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA
    Can J Urol 20:6897-906. 2013

Collaborators

Detail Information

Publications23

  1. doi request reprint Prostate Biopsy Markers of Inflammation are Associated with Risk of Clinical Progression of Benign Prostatic Hyperplasia: Findings from the MTOPS Study
    Kathleen C Torkko
    Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado Electronic address
    J Urol 194:454-61. 2015
    ..Factors associated with worsening of benign prostatic hyperplasia are not well understood. We measured inflammatory markers from prostate biopsies to study if inflammation is related to clinical progression of benign prostatic hyperplasia...
  2. doi request reprint VDR and SRD5A2 polymorphisms combine to increase risk for prostate cancer in both non-Hispanic White and Hispanic White men
    Kathleen C Torkko
    Department of Pathology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado 80045, USA
    Clin Cancer Res 14:3223-9. 2008
    ..This study tested the interactions of VDR (CDX2, FokI) and SRD5A2 (V89L, A49T) polymorphisms, and their associations with prostate cancer...
  3. ncbi request reprint B7-H4 (DD-O110) is overexpressed in high risk uterine endometrioid adenocarcinomas and inversely correlated with tumor T-cell infiltration
    Takashi Miyatake
    Department of Pathology, University of Colorado at Denver and Health Sciences Center, 12800 E 19th Ave Aurora, CO 80010, USA
    Gynecol Oncol 106:119-27. 2007
    ..B7-H4 expression was evaluated in apoptotic tumor cells...
  4. doi request reprint ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease
    Meenakshi Singh
    Department of Pathology, University of Colorado Health Sciences Center, Aurora, CO 80045, USA
    Mod Pathol 21:912-23. 2008
    ..It may help identify women who would most benefit from chemotherapy. Furthermore, if expression of ZEB1 in type II endometrial cancers could be reversed, it might be exploited as therapy for these highly aggressive tumors...
  5. doi request reprint Detection of B7-H4 and p53 in pancreatic cancer: potential role as a cytological diagnostic adjunct
    Nida S Awadallah
    Division of Gastroenterology, Department of Internal Medicine, University of Colorado at Denver and Health Science Center, Aurora, CO 80045, USA
    Pancreas 36:200-6. 2008
    ..This study compared p53 expression with B7-H4, a novel cancer biomarker, in pancreatic ductal adenocarcinoma (PDA) resection specimens and in a pilot series of endoscopic ultrasound-guided fine-needle aspirations (EUS-FNAs)...
  6. pmc Pseudolumen size and perimeter in prostate cancer: correlation with patient outcome
    Kenneth A Iczkowski
    Department of Pathology, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
    Prostate Cancer 2011:693853. 2011
    ..015), space size was smaller (P = .11), perimeters were smaller (P = .04), and perimeter/size ratio was higher (P = .02). In conclusion, digitally measured pseudolumen size and shape may associate with outcome...
  7. ncbi request reprint B7-h4 expression in a range of breast pathology: correlation with tumor T-cell infiltration
    Kimberly C Mugler
    Department of Pathology, University of Colorado at Denver and Health Sciences Center, 12800 East 19th Avenue, Aurora, CO 80045, USA
    Appl Immunohistochem Mol Morphol 15:363-70. 2007
    ..002). The cellular distribution of B7-H4 appears altered in the spectrum of normal to malignant breast. Its overexpression may help cancers avoid immune detection...
  8. doi request reprint Preoperative prediction of unifocal, unilateral, margin-negative, and small volume prostate cancer
    Kenneth A Iczkowski
    Department of Pathology, University of Colorado Health Science Center, Denver, Colorado 80045, USA
    Urology 71:1166-71. 2008
    ..Subtotal gland ablation by minimally invasive therapies such as cryotherapy demands preoperative prediction of unifocal, unilateral, margin-negative, and small volume (less than 0.5 mL) cancer...
  9. pmc Reduced expression of GDF-15 is associated with atrophic inflammatory lesions of the prostate
    James R Lambert
    Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado
    Prostate 75:255-65. 2015
    ..Growth differentiation factor-15 (GDF-15) is highly expressed in the prostate and has been associated with inflammation and tumorigenesis...
  10. pmc Anterior tumors of the prostate: diagnosis and significance
    Priya N Werahera
    University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado, USA
    Can J Urol 20:6897-906. 2013
    ..Consequently, tumors originating from the anterior apical region and transition zones may be under-sampled. We examined whether addition of transrectal anterior biopsy (TAB) would improve efficacy of prostate biopsies...
  11. doi request reprint p16(INK4a) is superior to high-risk human papillomavirus testing in cervical cytology for the prediction of underlying high-grade dysplasia
    Panduka Samarawardana
    Department of Pathology, Stony Brook University Medical Center, Stony Brook, New York 11794 8691, USA
    Cancer Cytopathol 118:146-56. 2010
    ....
  12. pmc Digital quantification of five high-grade prostate cancer patterns, including the cribriform pattern, and their association with adverse outcome
    Kenneth A Iczkowski
    Department of Pathology, University of Colorado, Denver School of Medicine, Aurora, CO 80045, USA
    Am J Clin Pathol 136:98-107. 2011
    ..The cribriform pattern has particularly adverse implications for outcome...
  13. pmc Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers
    Hamid H Gari
    Department of Pathology, University of Colorado School of Medicine, Aurora, CO, USA
    Oncotarget 7:15757-71. 2016
    ....
  14. ncbi request reprint Clinical staging of prostate cancer: a computer-simulated study of transperineal prostate biopsy
    E David Crawford
    Radiation Oncology, Department of Pathology, University of Colorado Health Sciences Center at Fitzsimons, Aurora, CO 80045, USA
    BJU Int 96:999-1004. 2005
    ..To identify the precise location of prostate cancer within the gland and thus possibly permit more aggressive therapy of the lesion, while potentially sparing the noncancerous gland from ablative therapy...
  15. ncbi request reprint Trials of new germ cell immunohistochemical stains in 93 extragonadal and metastatic germ cell tumors
    Kenneth A Iczkowski
    Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, FL 32608, USA
    Hum Pathol 39:275-81. 2008
    ..For embryonal carcinoma, OCT3/4 was superior to PLAP and more specific than CD30. D2-40 is recommended to discriminate between seminoma and embryonal carcinoma...
  16. ncbi request reprint Human papillomavirus testing and molecular markers of cervical dysplasia and carcinoma
    Donna Dehn
    Department of Pathology, University of Colorado at Denver and Health Sciences Center, Aurora, Colorado 80045, USA
    Cancer 111:1-14. 2007
    ....
  17. ncbi request reprint B7-H4 overexpression in ovarian tumors
    Barbara Tringler
    Department of Pathology, University of Colorado Health Sciences Center, B 216, 4200 East Ninth Avenue, Denver, CO 80262, USA
    Gynecol Oncol 100:44-52. 2006
    ....
  18. pmc Cooperative Dynamics of AR and ER Activity in Breast Cancer
    Nicholas C D'Amato
    Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, Colorado
    Mol Cancer Res 14:1054-1067. 2016
    ..In addition, single-agent efficacy may be possible in tumors resistant to traditional endocrine therapy, as clinical specimens of recurrent disease demonstrate AR expression in tumors with absent or refractory ER...
  19. ncbi request reprint Steroid receptor coactivator AIB1 in endometrial carcinoma, hyperplasia and normal endometrium: Correlation with clinicopathologic parameters and biomarkers
    Nicole N Balmer
    Department of Pathology, University of Colorado Health Sciences Center, Denver, CO 80045, USA
    Mod Pathol 19:1593-605. 2006
    ..Future studies correlating expression with response to hormonal therapy may be beneficial...
  20. ncbi request reprint Association of RNASEL variants with prostate cancer risk in Hispanic Caucasians and African Americans
    Stacie J Shook
    Department of Cellular and Structural Biology, The University of Texas Health Science Center, San Antonio, Texas 78229 3900, USA
    Clin Cancer Res 13:5959-64. 2007
    ..The RNASEL gene at 1q25 has been identified as a hereditary prostate cancer susceptibility gene, but to date, no study has investigated the role of RNASEL variants in Hispanic Caucasian men with prostate cancer...
  21. ncbi request reprint Association between an estrogen receptor alpha gene polymorphism and the risk of prostate cancer in black men
    Javier Hernandez
    Department of Urology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA
    J Urol 175:523-7. 2006
    ..Studies suggest that SNPs within ESR1 may be associated with an increased risk of prostate cancer. We evaluated the association of the XbaI and PvuII ESR1 SNPs and prostate cancer risk in 3 different racial/ethnic populations...
  22. ncbi request reprint Inflammation as a target for prostate cancer chemoprevention: pathological and laboratory rationale
    M Scott Lucia
    Department of Pathology and Preventive Medicine and Biometrics, Unibersity of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Urol 171:S30-4; discussion S35. 2004
    ..We review the literature addressing a potential causal role for chronic or recurrent inflammation or infection in the development of prostate cancer...
  23. ncbi request reprint Laterally directed biopsies detect more clinically threatening prostate cancer: computer simulated results
    Nozomu Kawata
    Department Urology, Nihon University School of Medicine, Tokyo, Japan
    Prostate 57:118-28. 2003
    ....