Keith R Thulborn

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. doi request reprint Quantitative Sodium MR Imaging: A Review of its Evolving Role in Medicine
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois at Chicago, 1801 West Taylor Street, Chicago IL60612 Electronic address
    Neuroimage . 2016
  2. doi request reprint My starting point: the discovery of an NMR method for measuring blood oxygenation using the transverse relaxation time of blood water
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois Medical Center at Chicago, Chicago, IL 60012, USA
    Neuroimage 62:589-93. 2012
  3. pmc Quantitative sodium MR imaging and sodium bioscales for the management of brain tumors
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimaging Clin N Am 19:615-24. 2009
  4. pmc MRI in the management of cerebrovascular disease to prevent stroke
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois Medical Center at Chicago, 1801 West Taylor Street, Suite 1307, Chicago, IL 60612, USA
    Neurol Clin 26:897-921, vii-viii. 2008
  5. ncbi request reprint Sodium MR imaging of acute and subacute stroke for assessment of tissue viability
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois at Chicago Medical Center, IL 60612, USA
    Neuroimaging Clin N Am 15:639-53, xi-xii. 2005
  6. ncbi request reprint Correlations of cortical activation and behavior during the application of newly learned categories
    Deborah M Little
    Department of Neurology and Rehabilitation and Anatomy and Cell Biology, Center for Stroke Research, University of Illinois at Chicago, Chicago, IL 60612, USA
    Brain Res Cogn Brain Res 25:33-47. 2005
  7. pmc Preserving the accuracy and resolution of the sodium bioscale from quantitative sodium MRI during intrasubject alignment across longitudinal studies
    Ian C Atkinson
    Center for Magnetic Resonance Research, University of Illinois, Chicago, Illinois, USA
    Magn Reson Med 68:751-61. 2012
  8. pmc Reproducibility of activation maps for longitudinal studies of visual function by functional magnetic resonance imaging
    Jing Ming
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
    Invest Ophthalmol Vis Sci 53:6153-63. 2012
  9. pmc Impact of gradient timing error on the tissue sodium concentration bioscale measured using flexible twisted projection imaging
    Aiming Lu
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL 60612, United States
    J Magn Reson 213:176-81. 2011
  10. ncbi request reprint Event-related fMRI of category learning: differences in classification and feedback networks
    Deborah M Little
    Center for Stroke Research, Department of Neurology and Rehabilitation, University of Illinois at Chicago, 60612, USA
    Brain Cogn 60:244-52. 2006

Research Grants

  1. TISSUE VIABILITY IN STROKE BY SODIUM MR IMAGING
    Keith Thulborn; Fiscal Year: 2002
  2. TISSUE VIABILITY IN STROKE BY SODIUM MR IMAGING
    Keith Thulborn; Fiscal Year: 2003

Detail Information

Publications34

  1. doi request reprint Quantitative Sodium MR Imaging: A Review of its Evolving Role in Medicine
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois at Chicago, 1801 West Taylor Street, Chicago IL60612 Electronic address
    Neuroimage . 2016
    ..The final challenge is for the technology to be supplied on clinical ≥3T scanners...
  2. doi request reprint My starting point: the discovery of an NMR method for measuring blood oxygenation using the transverse relaxation time of blood water
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois Medical Center at Chicago, Chicago, IL 60012, USA
    Neuroimage 62:589-93. 2012
    ..This mechanism was subsequently shown to be the basis of localized MR signal changes associated with local brain function. This connection led to the fMRI revolution in human brain mapping...
  3. pmc Quantitative sodium MR imaging and sodium bioscales for the management of brain tumors
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimaging Clin N Am 19:615-24. 2009
    ..These suggestions are speculative and still being examined, but are presented to challenge the medical community to be receptive to changes in the standard of care when that standard continues to fail...
  4. pmc MRI in the management of cerebrovascular disease to prevent stroke
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois Medical Center at Chicago, 1801 West Taylor Street, Suite 1307, Chicago, IL 60612, USA
    Neurol Clin 26:897-921, vii-viii. 2008
    ..These MRI procedures are demonstrated by clinical cases of advanced cerebrovascular pathology in which treatment varied from medical management to surgical intervention...
  5. ncbi request reprint Sodium MR imaging of acute and subacute stroke for assessment of tissue viability
    Keith R Thulborn
    Center for Magnetic Resonance Research, University of Illinois at Chicago Medical Center, IL 60612, USA
    Neuroimaging Clin N Am 15:639-53, xi-xii. 2005
    ..With infarction, baseline TSC values of less than 45 mmol/L increase at variable rates to approximately 70 mmol/L, allowing monitoring of the progression of stroke pathophysiology...
  6. ncbi request reprint Correlations of cortical activation and behavior during the application of newly learned categories
    Deborah M Little
    Department of Neurology and Rehabilitation and Anatomy and Cell Biology, Center for Stroke Research, University of Illinois at Chicago, Chicago, IL 60612, USA
    Brain Res Cogn Brain Res 25:33-47. 2005
    ..These initial stages of recruitment are followed by specialization across the same network which is observed as a reduction in activation with continued improvements in behavioral performance...
  7. pmc Preserving the accuracy and resolution of the sodium bioscale from quantitative sodium MRI during intrasubject alignment across longitudinal studies
    Ian C Atkinson
    Center for Magnetic Resonance Research, University of Illinois, Chicago, Illinois, USA
    Magn Reson Med 68:751-61. 2012
    ..0 T demonstrating this registration approach to sodium data illustrate preservation of quantification accuracy during alignment of sodium magnetic resonance images acquired from the same subject during different imaging sessions...
  8. pmc Reproducibility of activation maps for longitudinal studies of visual function by functional magnetic resonance imaging
    Jing Ming
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
    Invest Ophthalmol Vis Sci 53:6153-63. 2012
    ....
  9. pmc Impact of gradient timing error on the tissue sodium concentration bioscale measured using flexible twisted projection imaging
    Aiming Lu
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL 60612, United States
    J Magn Reson 213:176-81. 2011
    ..The measured timing errors can be corrected prospectively or retrospectively to obtain accurate TSC values...
  10. ncbi request reprint Event-related fMRI of category learning: differences in classification and feedback networks
    Deborah M Little
    Center for Stroke Research, Department of Neurology and Rehabilitation, University of Illinois at Chicago, 60612, USA
    Brain Cogn 60:244-52. 2006
    ..However as learning progresses the networks change. This finding suggests that the cognitive strategies also change during prototype-distortion learning...
  11. pmc PCr/ATP ratio mapping of the human head by simultaneously imaging of multiple spectral peaks with interleaved excitations and flexible twisted projection imaging readout trajectories at 9.4 T
    Aiming Lu
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Magn Reson Med 69:538-44. 2013
    ..The phosphocreatine/γ-adenosine triphosphate ratio calculated for brain parenchyma (1-2) and the superficial temporalis muscle (3-5) are in agreement with literature values...
  12. pmc Clinically constrained optimization of flexTPI acquisition parameters for the tissue sodium concentration bioscale
    Ian C Atkinson
    Center for MR Research, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Magn Reson Med 66:1089-99. 2011
    ..4 and 3.0T. The effect of signal loss during data collection on sodium quantification bias and image signal-to-noise ratio are discussed...
  13. ncbi request reprint Prototype-distortion category learning: a two-phase learning process across a distributed network
    Deborah M Little
    Center for Stroke Research, Department of Neurology and Rehabilitation, University of Illinois at Chicago, 60612, USA
    Brain Cogn 60:233-43. 2006
    ....
  14. pmc Quantitative sodium imaging with a flexible twisted projection pulse sequence
    Aiming Lu
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    Magn Reson Med 63:1583-93. 2010
    ..6 +/- 0.6 micromol/g wet weight and 27.6 +/- 1.2 micromol/g wet weight, respectively...
  15. doi request reprint Vital signs and cognitive function are not affected by 23-sodium and 17-oxygen magnetic resonance imaging of the human brain at 9.4 T
    Ian C Atkinson
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Magn Reson Imaging 32:82-7. 2010
    ..To evaluate the effect of 23-sodium ((23)Na) and 17-oxygen ((17)O) magnetic resonance imaging (MRI) at 9.4 (T) on vital signs and cognitive function of the human brain...
  16. doi request reprint Feasibility of mapping the tissue mass corrected bioscale of cerebral metabolic rate of oxygen consumption using 17-oxygen and 23-sodium MR imaging in a human brain at 9.4 T
    Ian C Atkinson
    Center for Magnetic Resonance Research, University of Illinois at Chicago, IL 60612, USA
    Neuroimage 51:723-33. 2010
    ..The proposed technique is demonstrated in the human brain using a 9.4 T MR scanner optimized for human brain imaging...
  17. doi request reprint Investigating the consistency of brain activation using individual trial analysis of high-resolution fMRI in the human primary visual cortex
    Ajay K Nemani
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 47:1417-24. 2009
    ..The implication of this observation for neuroplasticity and behavioral consistency at the level of functional units is discussed...
  18. ncbi request reprint Neural basis for the processes that underlie visually guided and internally guided force control in humans
    David E Vaillancourt
    School of Kinesiology, Department of Neurology, University of Illinois at Chicago, Chicago, Illinois 60608, USA
    J Neurophysiol 90:3330-40. 2003
    ..In contrast, a localized network in the prefrontal cortex retrieves force output from memory during internally guided actions...
  19. pmc Vertebrobasilar Flow Evaluation and Risk of Transient Ischaemic Attack and Stroke study (VERiTAS): rationale and design
    Sepideh Amin-Hanjani
    Department of Neurosurgery, Neuropsychiatric Institute, University of Illinois at Chicago, Chicago, IL 60612 5970, USA
    Int J Stroke 5:499-505. 2010
    ..Preliminary studies indicate that stroke risk in vertebrobasilar disease is strongly related to haemodynamic compromise, which can be measured noninvasively using quantitative magnetic resonance angiography...
  20. doi request reprint Detection of intracranial in-stent restenosis using quantitative magnetic resonance angiography
    Sepideh Amin-Hanjani
    Department of Neurosurgery, Neuropsychiatric Institute MC 799, University of Illinois at Chicago, Chicago, IL 60612 5970, USA
    Stroke 41:2534-8. 2010
    ..We examined the value of serial vessel flow measurements using quantitative magnetic resonance angiography (QMRA) in detection of ISR...
  21. ncbi request reprint Estimation and classification of fMRI hemodynamic response patterns
    Robert D Gibbons
    Center for Health Statistics, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 22:804-14. 2004
    ..The procedure is demonstrated on real data from an event-related design experiment of visually guided saccades and shown to be an effective alternative to existing methods...
  22. ncbi request reprint Changing patterns of brain activation during category learning revealed by functional MRI
    Deborah M Little
    Center for Magnetic Resonance Research, College of Medicine, University of Illinois, Room 1193, MC 707, 1801 W Taylor Street, Chicago, IL 60612, USA
    Brain Res Cogn Brain Res 22:84-93. 2004
    ..Of the two proposed mechanisms for learning, that of strengthened connectivity on a given network and that of selection of different networks, our data supports the former...
  23. doi request reprint Characterization and correction of system delays and eddy currents for MR imaging with ultrashort echo-time and time-varying gradients
    Ian C Atkinson
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, IL 60612, USA
    Magn Reson Med 62:532-7. 2009
    ..The ability of the proposed technique to reproducibly characterize small fixed delays (<50 micros) and short-time constant (<1 ms) eddy currents is demonstrated...
  24. doi request reprint Feasibility of 39-potassium MR imaging of a human brain at 9.4 Tesla
    Ian C Atkinson
    Center for Magnetic Resonance Research, University of Illinois, Chicago, Illinois, USA
    Magn Reson Med 71:1819-25. 2014
    ..To demonstrate the feasibility of performing 39-potassium MR imaging of a human brain...
  25. ncbi request reprint Survival and early differentiation of human neural stem cells transplanted in a nonhuman primate model of stroke
    Ben Z Roitberg
    Department of Neurosurgery, University of Illinois, Chicago, Illinois 60612, USA
    J Neurosurg 105:96-102. 2006
    ..Neural cell transplantation has been proposed as a treatment after stroke. The purpose of this study was to establish if human neural stem cells (HNSCs) could survive in the nonhuman primate brain after an ischemic event...
  26. ncbi request reprint Safety of human MRI at static fields above the FDA 8 T guideline: sodium imaging at 9.4 T does not affect vital signs or cognitive ability
    Ian C Atkinson
    Center for Magnetic Resonance Research, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Magn Reson Imaging 26:1222-7. 2007
    ..To assess whether exposure to a 9.4 T static magnetic field during sodium imaging at 105.92 MHz affects human vital signs and cognitive function...
  27. doi request reprint An FMRI study of saccadic and smooth-pursuit eye movement control in patients with age-related macular degeneration
    Deborah M Little
    Department of Neurology and Rehabilitation, University of Illinois at Chicago College of Medicine, Chicago, Illinois 60612, USA
    Invest Ophthalmol Vis Sci 49:1728-35. 2008
    ..To compare the cortical networks that underlie oculomotor function in patients with age-related macular degeneration (AMD) with those in normally sighted control subjects, using functional magnetic resonance imaging (fMRI)...
  28. ncbi request reprint Subthalamic nucleus and internal globus pallidus scale with the rate of change of force production in humans
    David E Vaillancourt
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 23:175-86. 2004
    ..In contrast, movements that require the internal regulation of the rate of change of force are associated with increased metabolic demand from the subthalamic nucleus and internal segment of the globus pallidus...
  29. pmc Vascular perfusion of choroidal melanoma by 3.0 tesla magnetic resonance imaging
    Bruce M Buerk
    Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, Illinois, USA
    Trans Am Ophthalmol Soc 102:209-15; discussion 215-7. 2004
    ..Specifically, we have examined lesion size and magnitude of maximum contrast enhancement in a series of intraocular melanomas before and during therapy...
  30. ncbi request reprint Magnetic resonance imaging of diffuse cerebral vasculitis associated with acute retinal necrosis
    Gary W Chung
    Department of Ophthalmology, University of Illinois at Chicago, 60612, USA
    Arch Ophthalmol 122:1719-20. 2004
  31. ncbi request reprint The cross-modal interaction between pain-related and saccade-related cerebral activation: a preliminary study by event-related functional magnetic resonance imaging
    Jiro Kurata
    Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Anesth Analg 101:449-56, table of contents. 2005
    ..In contrast, V-related activation was attenuated in PV. We propose that pain caused cross-modal suppression on the oculomotor activity and that an oculomotor task enhanced pain-related activation by triggering attention toward pain...
  32. ncbi request reprint Pursuit and saccadic eye movement subregions in human frontal eye field: a high-resolution fMRI investigation
    Caterina Rosano
    Neurobehavioral Studies Program, Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA
    Cereb Cortex 12:107-15. 2002
    ..These findings localize distinct pursuit and saccadic subregions of FEF in humans and demonstrate a high degree of homology in the organization of these FEF subregions in the human and the macaque monkey...
  33. ncbi request reprint Software for efficient visualization and analysis of multiple, large, multi-dimensional data sets from magnetic resonance imaging
    Steve Uttecht
    Department of Electrical Engineering, University of Pittsburgh, Pittsburgh, PA 15213, USA
    Comput Med Imaging Graph 26:73-89. 2002
    ..CliniViewer is compared to AnalyzeAVW and NIH Image, two popular MR image analysis tools. CliniViewer allows efficient clinical analysis of multiple images and maps from comprehensive clinical imaging protocols...
  34. ncbi request reprint Early decay of pain-related cerebral activation in functional magnetic resonance imaging: comparison with visual and motor tasks
    Jiro Kurata
    Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh, Pennsylvania 15213 2582, USA
    Anesthesiology 96:35-44. 2002
    ..The authors characterized the temporal evolution of such activation in comparison to that by conventional visual and motor tasks using functional magnetic resonance imaging...

Research Grants2

  1. TISSUE VIABILITY IN STROKE BY SODIUM MR IMAGING
    Keith Thulborn; Fiscal Year: 2002
    ..abstract_text> ..
  2. TISSUE VIABILITY IN STROKE BY SODIUM MR IMAGING
    Keith Thulborn; Fiscal Year: 2003
    ..abstract_text> ..