Affiliation: University of Texas Southwestern Medical Center
- Synapsins regulate use-dependent synaptic plasticity in the calyx of Held by a Ca2+/calmodulin-dependent pathwayJianyuan Sun
Center for Basic Neuroscience, University of Texas Southwestern Medical Center, 6000 Harry Hines Boulevard, Dallas, TX 75390 9111, USA
Proc Natl Acad Sci U S A 103:2880-5. 2006..Our results show that synapsins boost the release probability during high-frequency stimulation and suggest that this effect involves Ca2+/calmodulin-dependent phosphorylation of synapsins...
- A dual-Ca2+-sensor model for neurotransmitter release in a central synapseJianyuan Sun
Department of Neuroscience, The University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Nature 450:676-82. 2007..We propose a dual-Ca2+-sensor model of release that quantitatively describes the contributions of synchronous and asynchronous release under conditions of different presynaptic Ca2+ dynamics...
- Genetic analysis of synaptotagmin 2 in spontaneous and Ca2+-triggered neurotransmitter releaseZhiping P Pang
Department of Molecular Genetics, Center for Basic Neuroscience, Howard Hughes Medical Institute, UT Southwestern Medical Center, Dallas, TX 75390 9111, USA
EMBO J 25:2039-50. 2006....
- Dual modes of Munc18-1/SNARE interactions are coupled by functionally critical binding to syntaxin-1 N terminusMikhail Khvotchev
Department of Neuroscience, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
J Neurosci 27:12147-55. 2007..Viewed together, our data indicate that binding of Munc18 to the syntaxin N terminus unites different modes of Munc18/SNARE interactions and is essential for exocytic membrane fusion...