Eric M Snyder

Summary

Affiliation: University of Arizona
Country: USA

Publications

  1. pmc Variability in measures of exhaled breath na, influence of pulmonary blood flow and salivary na
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ 85721, USA
    Clin Med Insights Circ Respir Pulm Med 4:25-34. 2010
  2. pmc Genetics of beta2-adrenergic receptors and the cardiopulmonary response to exercise
    Eric M Snyder
    Department of Pharmacy Practice and Science, University of Arizona, Tucson AZ 85721, USA
    Exerc Sport Sci Rev 36:98-105. 2008
  3. pmc Influence of sildenafil on lung diffusion during exposure to acute hypoxia at rest and during exercise in healthy humans
    Eric M Snyder
    Department of Pharmacy Practice and Science, University of Arizona, 1703 E Mabel, Tucson, AZ 85721, USA
    Eur J Appl Physiol 103:421-30. 2008
  4. pmc Overnight hypoxic exposure and glucagon-like peptide-1 and leptin levels in humans
    Eric M Snyder
    Department of Pharmacy Practice and Science, University of Arizona, 1703 E Mabel, Tucson, AZ 85721, USA
    Appl Physiol Nutr Metab 33:929-35. 2008
  5. doi request reprint Effects of an inhaled β2-agonist on cardiovascular function and sympathetic activity in healthy subjects
    Eric M Snyder
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, 85721, USA
    Pharmacotherapy 31:748-56. 2011
  6. pmc Genetic variation of SCNN1A influences lung diffusing capacity in cystic fibrosis
    Sarah E Baker
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ, USA
    Med Sci Sports Exerc 44:2315-21. 2012
  7. doi request reprint Influence of genetic variation of the β2-adrenergic receptor on lung diffusion in patients with cystic fibrosis
    Brittany R Traylor
    Department of Pharmacy Practice and Science, University of Arizona, 1703 E Mabel, Tucson, AZ 85721, United States
    Pulm Pharmacol Ther 24:610-6. 2011
  8. pmc Genetic variation of αENaC influences lung diffusion during exercise in humans
    Sarah E Baker
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ 85721, United States
    Respir Physiol Neurobiol 179:212-8. 2011
  9. pmc Moderate intensity exercise mediates comparable increases in exhaled chloride as albuterol in individuals with cystic fibrosis
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ, USA Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA Electronic address
    Respir Med 109:1001-11. 2015
  10. doi request reprint Glycemic control influences lung membrane diffusion and oxygen saturation in exercise-trained subjects with type 1 diabetes: alveolar-capillary membrane conductance in type 1 diabetes
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, 1703 E Mabel, Tucson, AZ 85721, USA
    Eur J Appl Physiol 111:567-78. 2011

Collaborators

Detail Information

Publications37

  1. pmc Variability in measures of exhaled breath na, influence of pulmonary blood flow and salivary na
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ 85721, USA
    Clin Med Insights Circ Respir Pulm Med 4:25-34. 2010
    ....
  2. pmc Genetics of beta2-adrenergic receptors and the cardiopulmonary response to exercise
    Eric M Snyder
    Department of Pharmacy Practice and Science, University of Arizona, Tucson AZ 85721, USA
    Exerc Sport Sci Rev 36:98-105. 2008
    ..This review is focused on how the gene that encodes the ADRB2 influences the cardiopulmonary response to exercise. In addition, we discuss possible interactions between ADRB2 and other genes important in exercise performance...
  3. pmc Influence of sildenafil on lung diffusion during exposure to acute hypoxia at rest and during exercise in healthy humans
    Eric M Snyder
    Department of Pharmacy Practice and Science, University of Arizona, 1703 E Mabel, Tucson, AZ 85721, USA
    Eur J Appl Physiol 103:421-30. 2008
    ..57 +/- 0.29 vs. 0.41 +/- 0.16, P = 0.04). These results suggest no effect of sildenafil on DLCO, but an improvement in DM when corrected for changes in VC during short-term hypoxic exposure with exercise...
  4. pmc Overnight hypoxic exposure and glucagon-like peptide-1 and leptin levels in humans
    Eric M Snyder
    Department of Pharmacy Practice and Science, University of Arizona, 1703 E Mabel, Tucson, AZ 85721, USA
    Appl Physiol Nutr Metab 33:929-35. 2008
    ..45; p < 0.05), but no relation between SaO2 and GLP-1. These data confirm that leptin increases with hypoxic exposure in humans. Further study is needed to determine the influence of hypoxia and altitude on GLP-1 levels...
  5. doi request reprint Effects of an inhaled β2-agonist on cardiovascular function and sympathetic activity in healthy subjects
    Eric M Snyder
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, 85721, USA
    Pharmacotherapy 31:748-56. 2011
    ..To determine the effect of a short-acting, inhaled β(2)-adrenergic receptor agonist, albuterol sulfate, administered by nebulization, on cardiovascular function and sympathetic activity in healthy individuals...
  6. pmc Genetic variation of SCNN1A influences lung diffusing capacity in cystic fibrosis
    Sarah E Baker
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ, USA
    Med Sci Sports Exerc 44:2315-21. 2012
    ....
  7. doi request reprint Influence of genetic variation of the β2-adrenergic receptor on lung diffusion in patients with cystic fibrosis
    Brittany R Traylor
    Department of Pharmacy Practice and Science, University of Arizona, 1703 E Mabel, Tucson, AZ 85721, United States
    Pulm Pharmacol Ther 24:610-6. 2011
    ....
  8. pmc Genetic variation of αENaC influences lung diffusion during exercise in humans
    Sarah E Baker
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ 85721, United States
    Respir Physiol Neurobiol 179:212-8. 2011
    ..These findings could be important in determining who may be susceptible to pulmonary edema in response to various clinical or environmental conditions...
  9. pmc Moderate intensity exercise mediates comparable increases in exhaled chloride as albuterol in individuals with cystic fibrosis
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ, USA Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA Electronic address
    Respir Med 109:1001-11. 2015
    ....
  10. doi request reprint Glycemic control influences lung membrane diffusion and oxygen saturation in exercise-trained subjects with type 1 diabetes: alveolar-capillary membrane conductance in type 1 diabetes
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, 1703 E Mabel, Tucson, AZ 85721, USA
    Eur J Appl Physiol 111:567-78. 2011
    ..02). These results demonstrate that there is a reduction in lung diffusing capacity in aerobically fit athletes with T1DM at peak exercise, but suggests that maintaining near-normoglycemia potentially averts lung diffusion impairments...
  11. doi request reprint Effects of exercise intensity compared to albuterol in individuals with cystic fibrosis
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ, USA Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA Electronic address
    Respir Med 109:463-74. 2015
    ..We sought to compare the therapeutic benefits of exercise and their prescribed bronchodilator albuterol...
  12. doi request reprint Impaired lung diffusing capacity for nitric oxide and alveolar-capillary membrane conductance results in oxygen desaturation during exercise in patients with cystic fibrosis
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, Arizona, USA
    J Cyst Fibros 10:45-53. 2011
    ....
  13. pmc Genetic variation of the alpha subunit of the epithelial Na+ channel influences exhaled Na+ in healthy humans
    William T Foxx-Lupo
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ 85721, United States
    Respir Physiol Neurobiol 179:205-11. 2011
    ..05). The results are consistent with the notion that genetic variation of ENaC influences β(2)-adrenergic receptor stimulated Na(+) clearance in the lungs, as there was a significant reduction in exhaled Na(+) over time in the AA group...
  14. doi request reprint Comparison of intra-arterial and manual auscultation of blood pressure during submaximal exercise in humans
    Courtney M Wheatley
    a Department of Pharmacy Practice and Science, University of Arizona, Tucson, AZ 85721, USA
    Appl Physiol Nutr Metab 38:537-44. 2013
    ....
  15. doi request reprint Exercise is medicine in cystic fibrosis
    Courtney M Wheatley
    Department of Pharmacy Practice and Science, University of Arizona, Tucson, USA
    Exerc Sport Sci Rev 39:155-60. 2011
    ....
  16. doi request reprint Age-related differences in propofol dosing for procedural sedation in the Emergency Department
    Asad E Patanwala
    Department of Pharmacy Practice and Science, College of Pharmacy, University of Arizona, Tucson, Arizona
    J Emerg Med 44:823-8. 2013
    ..Propofol dose requirements may differ in the elderly due to age-related changes in pharmacokinetic or pharmacodynamic variables...
  17. ncbi request reprint Ventilatory responses to hypoxia and high altitude during sleep in Aconcagua climbers
    Eric M Snyder
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Wilderness Environ Med 18:138-45. 2007
    ..We examined the changes in ventilation during sleep at high altitude using the LifeShirt monitoring system on 2 climbers who were attempting to summit Mount Aconcagua (6956 m)...
  18. ncbi request reprint Relationship between cardiac output and oxygen consumption during upright cycle exercise in healthy humans
    Kenneth C Beck
    Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester MN 55905, USA
    J Appl Physiol 101:1474-80. 2006
    ..VO2. We conclude that the CardOut vs. VO2 relationship is not always linear, and negative curvature in the relationship is associated with higher fitness levels in normal, non-elite-athletic subjects...
  19. ncbi request reprint Reduced rate of alveolar-capillary recruitment and fall of pulmonary diffusing capacity during exercise in patients with heart failure
    Lyle J Olson
    Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
    J Card Fail 12:299-306. 2006
    ..We hypothesized for patients with CHF that the rate of rise of exercise DLCO is reduced compared to healthy controls and falls near end-exercise consistent with progressive interstitial edema...
  20. ncbi request reprint The effect of 18 h of simulated high altitude on left ventricular function
    Jesper Kjaergaard
    Department of Cardiology, Copenhagen University Hospital Rigshospitalet, Copenhagen Ø, 2100, Denmark
    Eur J Appl Physiol 98:411-8. 2006
    ..The significant changes in filling pattern and IVRT in the setting of normal and unchanged systolic function, indicates that hypoxia induces mild diastolic dysfunction in young healthy individuals...
  21. ncbi request reprint Beta2-adrenergic receptor genotype and pulmonary function in patients with heart failure
    Eric M Snyder
    Division of Cardiovascular Diseases, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Chest 130:1527-34. 2006
    ..Common polymorphisms of the ADRB2 are associated with differences in ADRB2 function and therefore could differentially influence PF in patients with CHF...
  22. pmc Effects of acute changes in pulmonary wedge pressure on periodic breathing at rest in heart failure patients
    Thomas P Olson
    Mayo Clinic, College of Medicine, Rochester, MN 55905, USA
    Am Heart J 153:104.e1-7. 2007
    ..Although the mechanism(s) contributing to PB remain unclear, we examined whether changes in pulmonary wedge pressure (PWP) and pulmonary vascular resistance (PVR) alter PB in patients with established HF...
  23. ncbi request reprint Genotype related differences in beta2 adrenergic receptor density and cardiac function
    Eric M Snyder
    Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Med Sci Sports Exerc 38:882-6. 2006
    ..We sought to determine whether genetic variation of the ADRB2 influenced ADRB2 density and, consequently, resting cardiovascular function...
  24. ncbi request reprint Influence of beta2-adrenergic receptor genotype on airway function during exercise in healthy adults
    Eric M Snyder
    Gonda 5 369, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
    Chest 129:762-70. 2006
    ..There are known functional polymorphisms of the beta(2)AR, such as substitution of glycine for arginine at codon 16. We sought to determine if this variation in genotype differentially influences airway function during exercise...
  25. pmc Arg16Gly polymorphism of the beta2-adrenergic receptor is associated with differences in cardiovascular function at rest and during exercise in humans
    Eric M Snyder
    Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic and Foundation, 200 1st Street, SW, Rochester, MN 55905, USA
    J Physiol 571:121-30. 2006
    ..This may suggest possible genotype-related differences in baseline receptor function or density which causes phenotypic differences at rest that are sustained during short-term exercise...
  26. ncbi request reprint An open-circuit method for determining lung diffusing capacity during exercise: comparison to rebreathe
    Eric M Snyder
    Department of Internal Medicine, Division of Cardiovascular Disease, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    J Appl Physiol 99:1985-91. 2005
    ..The method is linearly associated with cardiac output, suggesting increased alveolar-capillary recruitment, and values were similar to the traditional rebreathe method...
  27. ncbi request reprint Impact of preload and afterload on global and regional right ventricular function and pressure: a quantitative echocardiography study
    Jesper Kjaergaard
    Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    J Am Soc Echocardiogr 19:515-21. 2006
    ..Several quantitative echocardiographic measures of global and regional right ventricular (RV) function have been proposed, but knowledge of the impact of increases in preload and afterload is limited...
  28. ncbi request reprint Beta-2 adrenergic receptor polymorphisms and the forearm blood flow response to mental stress
    Zhong Liu
    Dept of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Clin Auton Res 16:105-12. 2006
    ..Furthermore, the Arg16/Gly beta2-receptor polymorphism has no significant influence on the FBF or cardiovascular responses to mental stress...
  29. pmc Dietary sodium restriction and beta2-adrenergic receptor polymorphism modulate cardiovascular function in humans
    John H Eisenach
    Department of Anaesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Physiol 574:955-65. 2006
    ..This study provides evidence that dietary Na+ modulates effects of the Arg16Gly polymorphism on cardiovascular function...
  30. ncbi request reprint Isovolumic acceleration measured by tissue Doppler echocardiography is preload independent in healthy subjects
    Morten Dalsgaard
    Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
    Echocardiography 24:572-9. 2007
    ..IVA is believed to be less dependent on preload than previously proposed estimates. IVA has been measured at different locations, and studies have shown conflicting results...
  31. ncbi request reprint Short-term hypoxic exposure at rest and during exercise reduces lung water in healthy humans
    Eric M Snyder
    Departments of Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Appl Physiol (1985) 101:1623-32. 2006
    ..baseline). These data suggest that 17 h of hypoxic exposure at rest or with exercise resulted in a decrease in lung water in healthy humans...
  32. ncbi request reprint Repeat length polymorphism of the serotonin transporter gene influences pulmonary artery pressure in heart failure
    Thomas P Olson
    Mayo Clinic, College of Medicine, Rochester, MN 55905, USA
    Am Heart J 153:426-32. 2007
    ..This study examined the influence of a repeat length polymorphism in the promoter region of the 5-HTT gene on PAP between patients with HF and healthy control participants...
  33. ncbi request reprint Arginine 16 glycine beta2-adrenoceptor polymorphism and cardiovascular structure and function in patients with heart failure
    Robert Wolk
    Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Am Soc Echocardiogr 20:290-7. 2007
    ..In patients with CHF, but not in demographically matched healthy persons, the Arg16Gly polymorphism of the ADRB2 exerts important effects on cardiovascular structure and function, neurohormonal activation, and exercise tolerance...
  34. doi request reprint Human phenylethanolamine N-methyltransferase genetic polymorphisms and exercise-induced epinephrine release
    Yuan Ji
    Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Mayo Foundation, Rochester, Minnesota 55905, USA
    Physiol Genomics 33:323-32. 2008
    ..Our studies suggest that functionally significant variant sequence in the human PNMT gene might contribute to individual variation in levels of circulating epinephrine during exercise...
  35. pmc The relationship between resting lung-to-lung circulation time and peak exercise capacity in chronic heart failure patients
    Norman R Morris
    School of Physiotherapy and Exercise Science, Gold Coast Campus, Griffith University, Queensland, Australia
    J Card Fail 13:389-94. 2007
    ..A prolonged circulation time has been suggested as an index of increased severity of CHF. The aim of this study was to investigate the relationship between resting lung-to-lung circulation time (LLCT) and VO2peak in CHF...
  36. ncbi request reprint Genetic variation of the beta2-adrenergic receptor is associated with differences in lung fluid accumulation in humans
    Eric M Snyder
    Department of Internal Medicine, Mayo Clinic College of Medicine, 200 1st St, SW, Rochester, MN 55905, USA
    J Appl Physiol (1985) 102:2172-8. 2007
    ..Gly16, respectively, means+/-SD). These data suggest that subjects homozygous for Arg at amino acid 16 of the beta2AR have a greater susceptibility for lung fluid accumulation relative to subjects homozygous for Gly at this position...
  37. ncbi request reprint Blood pressure variation in healthy humans: a possible interaction with beta-2 adrenergic receptor genotype and renal epithelial sodium channels
    Eric M Snyder
    Division of Cardiovascular Diseases, Department of Internal Medicine, Gonda 5 369, Mayo Clinic and Foundation, 200 1st Street, SW, Rochester, MN 55905, USA
    Med Hypotheses 65:296-9. 2005
    ....