Elizabeth R Smith

Summary

Affiliation: University of Miami
Country: USA

Publications

  1. pmc Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression
    Elizabeth R Smith
    Department of Cell Biology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Papanicolaou Building, Room 415 M877 1550 NW 10th Avenue, Miami, FL, 33136, USA
    BMC Cell Biol 18:8. 2017
  2. pmc White spotting variant mouse as an experimental model for ovarian aging and menopausal biology
    Elizabeth R Smith
    Sylvester Comprehensive Cancer Center, Department ofMedicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Menopause 19:588-96. 2012
  3. pmc Nuclear entry of activated MAPK is restricted in primary ovarian and mammary epithelial cells
    Elizabeth R Smith
    Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 5:e9295. 2010
  4. pmc Follicle Depletion Provides a Permissive Environment for Ovarian Carcinogenesis
    Ying Wang
    Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida, USA Department of Cell Biology, University of Miami School of Medicine, Miami, Florida, USA
    Mol Cell Biol 36:2418-30. 2016
  5. pmc Differential requirement for Dab2 in the development of embryonic and extra-embryonic tissues
    Robert Moore
    Department of Cell Biology, University of Miami Miller School of Medicine, Miami, 33136, FL, USA
    BMC Dev Biol 13:39. 2013
  6. pmc Cyclooxygenase-1 inhibition prolongs postnatal ovarian follicle lifespan in mice
    Elizabeth R Smith
    Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida
    Biol Reprod 89:103. 2013
  7. pmc Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol
    Wensi Tao
    Department of Cell Biology, Molecular Cell and Developmental Biology Graduate Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136
    J Lipid Res 57:809-17. 2016
  8. pmc Disabled-2 Determines Commitment of a Pre-adipocyte Population in Juvenile Mice
    Wensi Tao
    Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, 33136, USA
    Sci Rep 6:35947. 2016
  9. pmc Hormonal induction and roles of Disabled-2 in lactation and involution
    Wensi Tao
    Sylvester Comprehensive Cancer Center, and Department of Cell Biology, Graduate Program in Molecular Cell and Developmental Biology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 9:e110737. 2014
  10. pmc Cell adhesion and sorting in embryoid bodies derived from N- or E-cadherin deficient murine embryonic stem cells
    Robert Moore
    Sylvester Comprehensive Cancer Center and Department of Cell Biology, University of Miami School of Medicine, Miami, FL 33136, USA
    Biol Open 3:121-8. 2014

Detail Information

Publications15

  1. pmc Nuclear envelope structural proteins facilitate nuclear shape changes accompanying embryonic differentiation and fidelity of gene expression
    Elizabeth R Smith
    Department of Cell Biology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Papanicolaou Building, Room 415 M877 1550 NW 10th Avenue, Miami, FL, 33136, USA
    BMC Cell Biol 18:8. 2017
    ..Here we further investigated the morphological changes of nuclei that accompany this differentiation...
  2. pmc White spotting variant mouse as an experimental model for ovarian aging and menopausal biology
    Elizabeth R Smith
    Sylvester Comprehensive Cancer Center, Department ofMedicine, University of Miami Miller School of Medicine, Miami, FL 33136, USA
    Menopause 19:588-96. 2012
    ....
  3. pmc Nuclear entry of activated MAPK is restricted in primary ovarian and mammary epithelial cells
    Elizabeth R Smith
    Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 5:e9295. 2010
    ..The MAPK/ERK1/2 serine kinases are primary mediators of the Ras mitogenic signaling pathway. Phosphorylation by MEK activates MAPK/ERK in the cytoplasm, and phospho-ERK is thought to enter the nucleus readily to modulate transcription...
  4. pmc Follicle Depletion Provides a Permissive Environment for Ovarian Carcinogenesis
    Ying Wang
    Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida, USA Department of Cell Biology, University of Miami School of Medicine, Miami, Florida, USA
    Mol Cell Biol 36:2418-30. 2016
    ..This finding suggests that follicle depletion provides a permissive ovarian environment for oncogenic transformation of epithelial cells, presenting a mechanism for the increased ovarian cancer risk in postmenopausal women. ..
  5. pmc Differential requirement for Dab2 in the development of embryonic and extra-embryonic tissues
    Robert Moore
    Department of Cell Biology, University of Miami Miller School of Medicine, Miami, 33136, FL, USA
    BMC Dev Biol 13:39. 2013
    ..To further clarify the in vivo roles of Dab2 in development and physiology, we designed a new floxed allele to delete dab2 gene...
  6. pmc Cyclooxygenase-1 inhibition prolongs postnatal ovarian follicle lifespan in mice
    Elizabeth R Smith
    Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, Florida
    Biol Reprod 89:103. 2013
    ..The current study suggests that inhibition of cyclooxygenase-1 may be able to delay ovarian aging and modulate menopausal timing. ..
  7. pmc Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol
    Wensi Tao
    Department of Cell Biology, Molecular Cell and Developmental Biology Graduate Program, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136
    J Lipid Res 57:809-17. 2016
    ..We conclude that the combination of Arh and Dab2 is responsible for the majority of adaptor function in LDLR endocytosis and LDLR-mediated cholesterol homeostasis. ..
  8. pmc Disabled-2 Determines Commitment of a Pre-adipocyte Population in Juvenile Mice
    Wensi Tao
    Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, 33136, USA
    Sci Rep 6:35947. 2016
    ..The finding provides evidence for a limited pre-adipocyte population in juvenile mammals and the requirement of Dab2 in the regulation of Ras/MAPK signal in the commitment of the precursor cells to adipose tissues...
  9. pmc Hormonal induction and roles of Disabled-2 in lactation and involution
    Wensi Tao
    Sylvester Comprehensive Cancer Center, and Department of Cell Biology, Graduate Program in Molecular Cell and Developmental Biology, University of Miami Miller School of Medicine, Miami, Florida, United States of America
    PLoS ONE 9:e110737. 2014
    ..We conclude that Dab2 expression is induced by hormones and Dab2 plays a role in modulating TGF-beta signaling to enhance apoptotic clearance of mammary epithelial cells during involution. ..
  10. pmc Cell adhesion and sorting in embryoid bodies derived from N- or E-cadherin deficient murine embryonic stem cells
    Robert Moore
    Sylvester Comprehensive Cancer Center and Department of Cell Biology, University of Miami School of Medicine, Miami, FL 33136, USA
    Biol Open 3:121-8. 2014
    ....
  11. pmc The primitive endoderm segregates from the epiblast in β1 integrin-deficient early mouse embryos
    Robert Moore
    Department of Cell Biology, University of Miami School of Medicine, Miami, Florida, USA
    Mol Cell Biol 34:560-72. 2014
    ....
  12. pmc Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice
    Wensi Tao
    Sylvester Comprehensive Cancer Center and Department of Cell Biology, Graduate Program in Cell and Developmental Biology, University of Miami School of Medicine Miami, FL, USA
    Front Cell Dev Biol 4:129. 2016
    ..The studies of mutant mice established that Dab2 plays multiple physiological roles through its endocytic functions and modulation of signal pathways...
  13. pmc Nuclear envelope structural defect underlies the main cause of aneuploidy in ovarian carcinogenesis
    Callinice D Capo-chichi
    Sylvester Comprehensive Cancer Center University of Miami, Miami, Florida, 33136, USA
    BMC Cell Biol 17:37. 2016
    ..Following up, we investigated the mechanisms of lamin A/C-suppression in promoting aneuploidy and synergy with p53 inactivation...
  14. pmc Ovarian ageing, follicle depletion, and cancer: a hypothesis for the aetiology of epithelial ovarian cancer involving follicle depletion
    Elizabeth R Smith
    Department of Medicine, University of Miami School of Medicine, Miami, FL, USA
    Lancet Oncol 9:1108-11. 2008
    ....
  15. pmc Increased expression of Syne1/nesprin-1 facilitates nuclear envelope structure changes in embryonic stem cell differentiation
    Elizabeth R Smith
    Sylvester Comprehensive Cancer Center, Department of Medicine, and Department of Obstetrics and Gynecology, University of Miami School of Medicine, Miami, Florida, USA
    Dev Dyn 240:2245-55. 2011
    ..We conclude that the nuclear envelope structural change accompanying differentiation likely participates in promoting the differential chromatin organization of the differentiated cells...