Harsharan K Singh
Affiliation: University of North Carolina
- Negative-staining electron microscopy of the urine for the detection of polyomavirus infectionsHarsharan K Singh
Electron Microscopy Services, UNC Hospitals, Department of Pathology and Laboratory Medicine, Campus Box 7525 UNC CH School of Medicine, The University of North Carolina at Chapel Hill, 27599, USA
Ultrastruct Pathol 30:329-38. 2006..EM can be used alone or in combination with urine cytology or PCR assays...
- Fine needle aspiration biopsy of soft tissue sarcomas: utility and diagnostic challengesHarsharan K Singh
Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Adv Anat Pathol 11:24-37. 2004....
- Presence of urinary Haufen accurately predicts polyomavirus nephropathyHarsharan K Singh
School of Medicine, University of North Carolina, Department of Pathology and Laboratory Medicine, Nephropathology Laboratory, Chapel Hill, NC 27599 7525, USA
J Am Soc Nephrol 20:416-27. 2009..It suggests that the detection of Haufen may serve as a noninvasive means to diagnose BK polyomavirus nephropathy in the urine...
- Diagnostic significance of peritubular capillary basement membrane multilaminations in kidney allografts: old concepts revisitedGeorge Liapis
Division of Nephropathology, Department of Pathology, University of North Carolina School of Medicine at Chapel Hill, Chapel Hill, NC 27599 7525, USA
Transplantation 94:620-9. 2012..Injury to peritubular capillaries and capillary basement membrane multilamination (PTCL) is a hallmark of antibody-mediated chronic renal allograft rejection. However, the predictive diagnostic value of PTCL is incompletely studied...
- Split-sample analysis of discarded cells from liquid-based Pap smear sampling devicesAllen C Rinas
Cytotechnology Program, Department of Allied Health Sciences, University of North Carolina at Chapel Hill, USA
Acta Cytol 50:55-62. 2006..Boxborough, Massachusetts, U.S.A) Pap smears in order to evaluate both the number and significance of cells that are routinely discarded with these devices after liquid-based specimens are collected...
- Polyomavirus nephropathy: quantitative urinary polyomavirus-Haufen testing accurately predicts the degree of intrarenal viral diseaseHarsharan K Singh
1 Division of Nephropathology, Department of Pathology and Laboratory Medicine, The University of North Carolina School of Medicine, Chapel Hill, NC 2 Division of Nephrology and Hypertension, Department of Medicine, The University of North Carolina, Chapel Hill, NC 3 Division of Abdominal Transplant Surgery, Department of Surgery, The University of North Carolina, Chapel Hill, NC
Transplantation 99:609-15. 2015..This article evaluates whether a quantitative PV-Haufen analysis, that is, the number of PV-Haufen shed per milliliter urine, predicts PVN disease grades and the severity of intrarenal PV replication...
- The oncogenic potential of BK-polyomavirus is linked to viral integration into the human genomeDaniel J Kenan
Division of Nephropathology, Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA
J Pathol 237:379-89. 2015..It is likely that dysregulation of large T-antigen, with persistent over-expression in non-lytic cells, promotes cell growth, genetic instability and neoplastic transformation...
- Polyomaviruses and disease: is there more to know than viremia and viruria?Volker Nickeleit
Division of Nephropathology, Department of Pathology and Laboratory Medicine, The University of North Carolina, Chapel Hill, North Carolina, USA
Curr Opin Organ Transplant 20:348-58. 2015..The emerging roles of polyomaviruses in oncogenesis, salivary gland disease, and post-bone marrow transplantation as well as novel Polyomavirus strains are highlighted...
- Polyomavirus nephropathy: morphology, pathophysiology, and clinical managementVolker Nickeleit
Department of Pathology, Nephropathology Laboratory, The University of North Carolina, Chapel Hill, North Carolina 27599 7525, USA
Curr Opin Nephrol Hypertens 12:599-605. 2003..The review will highlight the morphological, pathophysiological and clinical aspects of BK-virus nephropathy. New patient management strategies are discussed...
- Urine cytology findings of polyomavirus infectionsHarsharan K Singh
University of North Carolina at Chapel Hill, USA
Adv Exp Med Biol 577:201-12. 2006..The detection of decoy cells is compared to other techniques applicable to assess the activation of polyomaviruses in the urine (polymerase chain reaction (PCR) and EM)...
- Latent and productive polyomavirus infections of renal allografts: morphological, clinical, and pathophysiological aspectsVolker Nickeleit
University of North Carolina at Chapel Hill, USA
Adv Exp Med Biol 577:190-200. 2006..Special emphasis is placed on the clinical and pathophysiological significance of different histological stages of BKN...