Charles B Simone

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. doi request reprint PET-Based Thoracic Radiation Oncology
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, University of Pennsylvania, 3400 Civic Center Boulevard, TRC 2 West, Philadelphia, PA 19104, USA Electronic address
    PET Clin 11:319-32. 2016
  2. doi request reprint Palliative care for patients with locally advanced and metastatic non-small cell lung cancer
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Ann Palliat Med 2:178-88. 2013
  3. pmc Photodynamic therapy for lung cancer and malignant pleural mesothelioma
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA Electronic address
    Semin Oncol 41:820-30. 2014
  4. doi request reprint Stereotactic body radiation therapy for lung cancer
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Chest 143:1784-90. 2013
  5. doi request reprint Definitive dose thoracic radiation therapy in oligometastatic non-small cell lung cancer: A hypothesis-generating study
    Eric P Xanthopoulos
    Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Currently at Department of Radiation Oncology, Columbia University Medical Center, New York, New York
    Pract Radiat Oncol 5:e355-63. 2015
  6. ncbi request reprint Analysis of the Relationship Between Response to Chemotherapy and Response to Radiation Therapy in Patients With Non-Small Cell Lung Cancer Receiving Sequential Treatment
    Genevieve Maquilan
    Perelman Center for Advanced Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA
    Am J Clin Oncol . 2016
  7. pmc An IR Navigation System for Pleural PDT
    Timothy C Zhu
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA
    Front Phys 3:. 2015
  8. doi request reprint Multi-Institutional Prospective Study of Reirradiation with Proton Beam Radiotherapy for Locoregionally Recurrent Non-Small Cell Lung Cancer
    Hann Hsiang Chao
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania
    J Thorac Oncol 12:281-292. 2017
  9. doi request reprint Applications of Fluorodeoxyglucose PET/Computed Tomography in the Assessment and Prediction of Radiation Therapy-related Complications
    Sina Houshmand
    Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    PET Clin 10:555-71. 2015
  10. doi request reprint Efficacy and safety of stereotactic body radiation therapy for the treatment of pulmonary metastases from sarcoma: A potential alternative to resection
    Brian C Baumann
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania
    J Surg Oncol 114:65-9. 2016

Collaborators

Detail Information

Publications28

  1. doi request reprint PET-Based Thoracic Radiation Oncology
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, University of Pennsylvania, 3400 Civic Center Boulevard, TRC 2 West, Philadelphia, PA 19104, USA Electronic address
    PET Clin 11:319-32. 2016
    ..This article details the current uses of PET/CT in thoracic radiation oncology with a focus on lung cancer and describes expected future roles of PET/CT for thoracic tumors. ..
  2. doi request reprint Palliative care for patients with locally advanced and metastatic non-small cell lung cancer
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Ann Palliat Med 2:178-88. 2013
    ....
  3. pmc Photodynamic therapy for lung cancer and malignant pleural mesothelioma
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA Electronic address
    Semin Oncol 41:820-30. 2014
    ....
  4. doi request reprint Stereotactic body radiation therapy for lung cancer
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA
    Chest 143:1784-90. 2013
    ..This code is described, and its implications for patient care are discussed...
  5. doi request reprint Definitive dose thoracic radiation therapy in oligometastatic non-small cell lung cancer: A hypothesis-generating study
    Eric P Xanthopoulos
    Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania Currently at Department of Radiation Oncology, Columbia University Medical Center, New York, New York
    Pract Radiat Oncol 5:e355-63. 2015
    ..We report comparative outcomes in oligometastatic non-small cell lung cancer (NSCLC) treated with and without definitive, conventionally fractionated thoracic radiation therapy...
  6. ncbi request reprint Analysis of the Relationship Between Response to Chemotherapy and Response to Radiation Therapy in Patients With Non-Small Cell Lung Cancer Receiving Sequential Treatment
    Genevieve Maquilan
    Perelman Center for Advanced Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA
    Am J Clin Oncol . 2016
    ..We examine whether induction chemotherapy response predicts thoracic radiotherapy response in locally advanced or oligometastatic non-small cell lung cancer...
  7. pmc An IR Navigation System for Pleural PDT
    Timothy C Zhu
    Department of Radiation Oncology, School of Medicine, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA
    Front Phys 3:. 2015
    ..Preliminary data from a phantom shows superior light uniformity using this method. Light fluence uniformity from patient treatments is also shown with and without the correction method...
  8. doi request reprint Multi-Institutional Prospective Study of Reirradiation with Proton Beam Radiotherapy for Locoregionally Recurrent Non-Small Cell Lung Cancer
    Hann Hsiang Chao
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania
    J Thorac Oncol 12:281-292. 2017
    ..Proton radiotherapy (PRT) is ideally suited to minimize toxicity to previously irradiated organs. We report the safety/feasibility of PRT for NSCLC reirradiation in a prospective multi-institutional study...
  9. doi request reprint Applications of Fluorodeoxyglucose PET/Computed Tomography in the Assessment and Prediction of Radiation Therapy-related Complications
    Sina Houshmand
    Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA
    PET Clin 10:555-71. 2015
    ..This article discusses the role of PET/CT, and especially FDG-PET/CT, in radiotherapy complications. ..
  10. doi request reprint Efficacy and safety of stereotactic body radiation therapy for the treatment of pulmonary metastases from sarcoma: A potential alternative to resection
    Brian C Baumann
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, Pennsylvania
    J Surg Oncol 114:65-9. 2016
    ..We hypothesize that stereotactic body radiotherapy (SBRT) can be an alternative to surgery that can achieve high rates of local control (LC) with limited toxicity...
  11. doi request reprint Stage migration in planning PET/CT scans in patients due to receive radiotherapy for non-small-cell lung cancer
    Geoffrey A Geiger
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Perelman Center for Advanced Medicine, Philadelphia, PA
    Clin Lung Cancer 15:79-85. 2014
    ....
  12. doi request reprint PDT: What's Past Is Prologue
    Keith A Cengel
    University of Pennsylvania, Philadelphia, Pennsylvania
    Cancer Res 76:2497-9. 2016
    ..Cancer Res; 76(9); 2497-9. ©2016 AACRSee related article by Dougherty et al., Cancer Res 1978;38:2628-35Visit the Cancer Research 75(th) Anniversary timeline. ..
  13. doi request reprint Acupuncture for Dyspnea in Lung Cancer: Results of a Feasibility Trial
    Joshua Bauml
    Abramson Cancer Center at the University of Pennsylvania, Philadelphia, PA Division of Hematology Oncology, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
    Integr Cancer Ther 15:326-32. 2016
    ..This pilot study aimed to evaluate the feasibility and preliminary effectiveness of acupuncture for dyspnea among patients with LC...
  14. pmc Establishing the feasibility of the dosimetric compliance criteria of RTOG 1308: phase III randomized trial comparing overall survival after photon versus proton radiochemotherapy for inoperable stage II-IIIB NSCLC
    Tawfik Giaddui
    Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA
    Radiat Oncol 11:66. 2016
    ..To establish the feasibility of the dosimetric compliance criteria of the RTOG 1308 trial through testing against Intensity Modulation Radiation Therapy (IMRT) and Passive Scattering Proton Therapy (PSPT) plans...
  15. pmc Circulating Tumor Cells, DNA, and mRNA: Potential for Clinical Utility in Patients With Melanoma
    Melody J Xu
    Department of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Oncologist 21:84-94. 2016
    ....
  16. doi request reprint A moving target: Image guidance for stereotactic body radiation therapy for early-stage non-small cell lung cancer
    Michael N Corradetti
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania Electronic address
    Pract Radiat Oncol 3:307-15. 2013
    ....
  17. doi request reprint Impact of PET staging in limited-stage small-cell lung cancer
    Eric P Xanthopoulos
    Department of Radiation Oncology, Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Thorac Oncol 8:899-905. 2013
    ..Although positron emission tomography computed tomography (PET-CT) has been widely used for small-cell lung cancer (SCLC) staging, no study has examined the clinical impact of PET staging in limited-stage (LS) SCLC...
  18. doi request reprint Evaluation of motion mitigation using abdominal compression in the clinical implementation of pencil beam scanning proton therapy of liver tumors
    Liyong Lin
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA, USA
    Med Phys . 2016
    ..This study reports a planning preparation workflow that can be used for beam angle selection and the evaluation of the efficacy of abdominal compression (AC) to mitigate motion...
  19. doi request reprint A Comparison of Dose Metrics to Predict Local Tumor Control for Photofrin-mediated Photodynamic Therapy
    Haixia Qiu
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA
    Photochem Photobiol . 2017
    ..Comparing dosimetric quantities, [1 O2 ]rx outperformed both PDT dose and fluence in predicting tumor response and correlating with LCR. This article is protected by copyright. All rights reserved...
  20. doi request reprint A Review of Shared Decision-Making and Patient Decision Aids in Radiation Oncology
    Kristina Demas Woodhouse
    Department of Radiation Oncology, Perelman School of Medicine at the University of Pennsylvania, 3400 Civic Center Blvd, TRC 2 West, Philadelphia, PA, 19104, USA
    J Cancer Educ . 2017
    ..Finally, this article reviews the findings from decision aid studies in radiation oncology and offers various strategies to effectively implement shared decision-making into clinical practice...
  21. pmc Definitive surgery and intraoperative photodynamic therapy: a prospective study of local control and survival for patients with pleural dissemination of non-small cell lung cancer
    Charles B Simone
    Department of Radiation Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Proc SPIE Int Soc Opt Eng 8931:. 2014
    ....
  22. doi request reprint Use of Survivorship Care Plans and Analysis of Patient-Reported Outcomes in Multinational Patients With Lung Cancer
    Abigail T Berman
    University of Pennsylvania, Philadelphia, PA
    J Oncol Pract 12:e527-35. 2016
    ..Patient-reported outcomes (PROs) have been shown to be prognostic for survival. We have analyzed emerging patterns of longitudinal PROs collected in the development of survivorship care plans (SCPs)...
  23. pmc Immunotherapy in locally-advanced non-small cell lung cancer: releasing the brakes on consolidation?
    Abigail T Berman
    Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Transl Lung Cancer Res 5:138-42. 2016
    ..Despite the promising findings of this trial, numerous questions regarding immunotherapy for LA-NSCLC remain, and several additional immunotherapy trials are underway or planned in this patient population. ..
  24. doi request reprint Prospective study of proton beam radiation therapy for adjuvant and definitive treatment of thymoma and thymic carcinoma: Early response and toxicity assessment
    Jennifer Vogel
    Hospital of the University of Pennsylvania, Department of Radiation Oncology, Philadelphia, United States Electronic address
    Radiother Oncol 118:504-9. 2016
    ..However, toxicity may reduce its overall benefit. We hypothesized that double-scattering proton beam therapy (DS-PT) can achieve excellent local control with limited toxicity in patients with thymic malignancies...
  25. doi request reprint The use of proton therapy in the treatment of lung cancers
    Charles B Simone
    From the Department of Radiation Oncology, University of Pennsylvania, Philadelphia, PA and Department of Radiation Oncology, University of Washington Medical Center, Seattle, WA
    Cancer J 20:427-32. 2014
    ..This review discusses the rationales for and current uses of proton therapy to treat lung cancer, and it highlights key studies of proton therapy to treat early-stage and locally advanced NSCLC. ..
  26. pmc Measuring the Physiologic Properties of Oral Lesions Receiving Fractionated Photodynamic Therapy
    Shannon M Gallagher-Colombo
    Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
    Photochem Photobiol 91:1210-8. 2015
    ..Results establish that the integration of DRS into PDT of early-stage oral disease is feasible, and motivates further studies to evaluate its predictive and dosimetric value. ..
  27. doi request reprint Palliative radiotherapy for advanced malignancies in a changing oncologic landscape: guiding principles and practice implementation
    Joshua A Jones
    Perelman Center for Advanced Medicine, 3400 Civic Center Boulevard, TRC 2 West, Philadelphia, PA 19104, USA
    Ann Palliat Med 3:192-202. 2014
    ....
  28. pmc Tracking viable circulating tumor cells (CTCs) in the peripheral blood of non-small cell lung cancer (NSCLC) patients undergoing definitive radiation therapy: pilot study results
    Jay F Dorsey
    Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
    Cancer 121:139-49. 2015
    ..However, to the authors' knowledge, the effect of radiation therapy (RT) on CTCs in patients with non-small cell lung cancer (NSCLC) has not been previously explored...