Youngho Seo

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Correction of photon attenuation and collimator response for a body-contouring SPECT/CT imaging system
    Youngho Seo
    Department of Radiology, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107 1739, USA
    J Nucl Med 46:868-77. 2005
  2. pmc Quantitative accuracy of PET/CT for image-based kinetic analysis
    Youngho Seo
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0946, USA
    Med Phys 35:3086-9. 2008
  3. pmc In vivo microCT imaging of rodent cerebral vasculature
    Youngho Seo
    Center for Molecular and Functional Imaging, Department of Radiology, University of California, San Francisco, CA 94143, USA
    Phys Med Biol 53:N99-107. 2008
  4. pmc In vivo tumor grading of prostate cancer using quantitative 111In-capromab pendetide SPECT/CT
    Youngho Seo
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0946, USA
    J Nucl Med 51:31-6. 2010
  5. ncbi request reprint Rodent brain imaging with SPECT/CT
    Youngho Seo
    Department of Radiology, University of California, San Francisco, California 94143, USA
    Med Phys 34:1217-20. 2007
  6. ncbi request reprint Progress in SPECT/CT imaging of prostate cancer
    Youngho Seo
    Department of Radiology, University of California, San Francisco, California, USA
    Technol Cancer Res Treat 5:329-36. 2006
  7. ncbi request reprint Calculation and validation of the use of effective attenuation coefficient for attenuation correction in In-111 SPECT
    Youngho Seo
    Physics Research Laboratory, Department of Radiology, University of California, San Francisco, California 94143, USA
    Med Phys 32:3628-35. 2005
  8. pmc Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas
    Arun K Iyer
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
    Cancer Res 71:2428-32. 2011
  9. ncbi request reprint Partial-volume correction in PET: validation of an iterative postreconstruction method with phantom and patient data
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94107, USA
    J Nucl Med 48:802-10. 2007
  10. doi request reprint Correcting tumour SUV for enhanced bone marrow uptake: retrospective 18F-FDG PET/CT studies
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, USA
    Nucl Med Commun 29:359-66. 2008

Collaborators

Detail Information

Publications41

  1. ncbi request reprint Correction of photon attenuation and collimator response for a body-contouring SPECT/CT imaging system
    Youngho Seo
    Department of Radiology, University of California San Francisco, 185 Berry Street, San Francisco, CA 94107 1739, USA
    J Nucl Med 46:868-77. 2005
    ..In this article, we evaluate a novel iterative reconstruction algorithm using the SPECT/CT data obtained from phantoms and (111)In-capromab pendetide patient studies...
  2. pmc Quantitative accuracy of PET/CT for image-based kinetic analysis
    Youngho Seo
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0946, USA
    Med Phys 35:3086-9. 2008
    ..Within these constraints, the list-mode data acquired with the Biograph 16 PET/CT system are quantitatively accurate for image-based kinetic analysis...
  3. pmc In vivo microCT imaging of rodent cerebral vasculature
    Youngho Seo
    Center for Molecular and Functional Imaging, Department of Radiology, University of California, San Francisco, CA 94143, USA
    Phys Med Biol 53:N99-107. 2008
    ..g. iopromide) and therefore does not require specialized small animal specific contrast agent that has comparatively long in vivo residence time...
  4. pmc In vivo tumor grading of prostate cancer using quantitative 111In-capromab pendetide SPECT/CT
    Youngho Seo
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94143 0946, USA
    J Nucl Med 51:31-6. 2010
    ..We have developed an in vivo method to quantify antibody uptake using (111)In-capromab pendetide SPECT combined with CT (SPECT/CT). Our goal was to evaluate this method for potential grading of prostate tumors...
  5. ncbi request reprint Rodent brain imaging with SPECT/CT
    Youngho Seo
    Department of Radiology, University of California, San Francisco, California 94143, USA
    Med Phys 34:1217-20. 2007
    ..We have demonstrated a capability of imaging regions of cerebral blood flow deficit in MCAO rat brains in vivo using a pinhole SPECT dedicated to small animal imaging...
  6. ncbi request reprint Progress in SPECT/CT imaging of prostate cancer
    Youngho Seo
    Department of Radiology, University of California, San Francisco, California, USA
    Technol Cancer Res Treat 5:329-36. 2006
    ..There were also changes in interpretations for 4 of 12 studies although the changes were not sufficient to alter prognosis or the patient treatment plan...
  7. ncbi request reprint Calculation and validation of the use of effective attenuation coefficient for attenuation correction in In-111 SPECT
    Youngho Seo
    Physics Research Laboratory, Department of Radiology, University of California, San Francisco, California 94143, USA
    Med Phys 32:3628-35. 2005
    ..Although these results are specific to 111In, the foundation could easily be extended to other multiple-energy isotopes...
  8. pmc Novel human single chain antibody fragments that are rapidly internalizing effectively target epithelioid and sarcomatoid mesotheliomas
    Arun K Iyer
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA
    Cancer Res 71:2428-32. 2011
    ....
  9. ncbi request reprint Partial-volume correction in PET: validation of an iterative postreconstruction method with phantom and patient data
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, San Francisco, CA 94107, USA
    J Nucl Med 48:802-10. 2007
    ..An iterative postreconstruction method was evaluated that corrects for PVEs without a priori knowledge of tumor size or background...
  10. doi request reprint Correcting tumour SUV for enhanced bone marrow uptake: retrospective 18F-FDG PET/CT studies
    Boon Keng Teo
    Department of Radiology, University of California, San Francisco, USA
    Nucl Med Commun 29:359-66. 2008
    ..We tested this hypothesis by quantifying total F-FDG uptake in the bone marrow of patients with visibly enhanced bone marrow uptake and computing its effect on tumour SUV...
  11. pmc Tumor dosimetry using [124I]m-iodobenzylguanidine microPET/CT for [131I]m-iodobenzylguanidine treatment of neuroblastoma in a murine xenograft model
    Youngho Seo
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
    Mol Imaging Biol 14:735-42. 2012
    ....
  12. pmc The effect of internalizing human single chain antibody fragment on liposome targeting to epithelioid and sarcomatoid mesothelioma
    Arun K Iyer
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA 94143, USA
    Biomaterials 32:2605-13. 2011
    ....
  13. pmc Biodistributions of 177Lu- and 111In-labeled 7E11 antibodies to prostate-specific membrane antigen in xenograft model of prostate cancer and potential use of 111In-7E11 as a pre-therapeutic agent for 177Lu-7E11 radioimmunotherapy
    Mei Hsiu Pan
    Center for Molecular and Functional Imaging, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143, USA
    Mol Imaging Biol 11:159-66. 2009
    ..To serve as a radioimmunotherapeutic agent, a kinetically inert conjugate is desired to maximize tumor uptake and tumor radiation dose with minimal nonspecific exposure to bone marrow and other major organs...
  14. pmc Targeting prostate cancer cells in vivo using a rapidly internalizing novel human single-chain antibody fragment
    Jiang He
    Department of Radiology and Biomedical Imaging, Center for Molecular and Functional Imaging, University of California at San Francisco, San Francisco, California 94143, USA
    J Nucl Med 51:427-32. 2010
    ..The objective of this study was to evaluate the tumor targeting of an internalizing human antibody fragment, a small-size platform, to provide high contrast in a mouse model of human prostate carcinoma...
  15. pmc Technological development and advances in single-photon emission computed tomography/computed tomography
    Youngho Seo
    Department of Radiology, University of California, San Francisco, San Francisco, CA, USA
    Semin Nucl Med 38:177-98. 2008
    ....
  16. pmc Multipinhole collimator with 20 apertures for a brain SPECT application
    Tzu Cheng Lee
    Physics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94107
    Med Phys 41:112501. 2014
    ..6 × 10(-5) to 1.6 × 10(-3)) for dopamine transporter (DaT) imaging of the striatum over the conventional SPECT parallel-hole collimators by use of custom-designed 20 multipinhole (20-MPH) collimators with apertures of 0.75 cm diameter...
  17. pmc Combining dynamic and ECG-gated ⁸²Rb-PET for practical implementation in the clinic
    George A Sayre
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94107, USA
    Nucl Med Commun 33:4-13. 2012
    ....
  18. pmc Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT
    Uttam Shrestha
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA USA
    IEEE Nucl Sci Symp Conf Rec (1997) 2014:. 2014
    ....
  19. pmc Mapping of lymphatic drainage from the prostate using filtered 99mTc-sulfur nanocolloid and SPECT/CT
    Youngho Seo
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, California 94107 1739, USA
    J Nucl Med 52:1068-72. 2011
    ..We have developed a practice procedure for prostate lymphoscintigraphy using SPECT/CT and filtered (99m)Tc-sulfur nanocolloid, as an alternative to the proprietary product (99m)Tc-Nanocoll, which is not approved in the United States...
  20. pmc Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems
    Swati S More
    Departments of Bioengineering and Therapeutic Sciences, UCSF School of Medicine and UCSF Benioff Children s Hospital, San Francisco, California 94158, USA
    Clin Cancer Res 17:2339-49. 2011
    ....
  21. pmc Measurement of absolute myocardial blood flow in humans using dynamic cardiac SPECT and 99mTc-tetrofosmin: Method and validation
    Uttam Shrestha
    Department of Radiology and Biomedical Imaging, University of California, 185 Berry St, Suite 350, San Francisco, CA, 94143 0946, USA
    J Nucl Cardiol . 2015
    ..The objective of this study was to measure myocardial blood flow (MBF) in humans using 99mTc-tetrofosmin and dynamic single-photon emission computed tomography (SPECT)...
  22. pmc The Effect of Magnetic Field on Positron Range and Spatial Resolution in an Integrated Whole-Body Time-Of-Flight PET/MRI System
    Shih Ying Huang
    Physics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA 94143
    IEEE Nucl Sci Symp Conf Rec (1997) 2014:. 2014
    ..Simulations and experimental results show that the in-plane spatial resolution was slightly improved at field strength as low as 3 Tesla, especially when resolving signal from high-energy positron emitters in the air-tissue boundary...
  23. pmc Bone remodeling after MR imaging-guided high-intensity focused ultrasound ablation: evaluation with MR imaging, CT, Na(18)F-PET, and histopathologic examination in a swine model
    Matthew D Bucknor
    From the Department of Radiology and Biomedical Imaging, University of California San Francisco, 185 Berry St, Suite 350, San Francisco, CA 94107 5705
    Radiology 274:387-94. 2015
    ....
  24. doi request reprint Intravenous vasopressin for the prevention of nontarget gastrointestinal embolization during liver-directed cancer treatment: experimental study in a porcine model
    Jeremy C Durack
    Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Vasc Interv Radiol 23:1505-12. 2012
    ..The aim of this study was to evaluate the potential for intravenous vasopressin to reduce the risk of nontarget gastrointestinal embolization during transcatheter liver-directed cancer therapies in a porcine model...
  25. pmc Radiation dose estimation using preclinical imaging with 124I-metaiodobenzylguanidine (MIBG) PET
    Chang Lae Lee
    Department of Radiology and Biomedical Imaging, UCSF Physics Research Laboratory, University of California, San Francisco, San Francisco, California 94143, USA
    Med Phys 37:4861-7. 2010
    ..The aim of this work was to estimate human-equivalent internal radiation dose of 124I-MIBG using PET/CT data in a murine xenograft model...
  26. pmc Ictal lack of binding to brain parenchyma suggests integrity of the blood-brain barrier for 11C-dihydroergotamine during glyceryl trinitrate-induced migraine
    Christoph J Schankin
    1 Headache Group, Department of Neurology, University of California San Francisco, San Francisco, CA, USA 3 Department of Neurology, University Hospital Bern Inselspital, University of Bern, Bern, Switzerland 4 Headache Group, NIHR Wellcome Trust, King s Clinical Research Facility, King s College London, London, UK
    Brain 139:1994-2001. 2016
    ....
  27. doi request reprint Technical Note: Fast respiratory motion estimation using sorted singles without unlist processing: A feasibility study
    Jaewon Yang
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA
    Med Phys . 2017
    ..The study aims to demonstrate the feasibility of fast respiratory motion estimation using singles data available as a sorted format in list-mode files acquired in an integrated PET/MRI system for a proof-of-concept...
  28. pmc Improved trabecular bone structure of 20-month-old male spontaneously hypertensive rats
    Tzu Cheng Lee
    Physics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA
    Calcif Tissue Int 95:282-91. 2014
    ..The observation of the association of hypertension with BMD and bone strength in hypertensive rats warrants further investigations of bone mass and strength in elderly males with hypertension. ..
  29. pmc Design and performance evaluation of a 20-aperture multipinhole collimator for myocardial perfusion imaging applications
    Jason D Bowen
    Physics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA
    Phys Med Biol 58:7209-26. 2013
    ..Systematic analyses showed PH20 collimators present improved diagnostic imaging performance over LEHR collimators, requiring only collimator exchange on existing SPECT cameras for their use. ..
  30. pmc The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type
    Mariia O Yuneva
    G W Hooper Research Foundation, University of California, San Francisco, San Francisco, CA 94143, USA
    Cell Metab 15:157-70. 2012
    ..Our results suggest that the metabolic profiles of tumors are likely to depend on both the genotype and tissue of origin and have implications regarding the design of therapies targeting tumor metabolism...
  31. pmc Patient-Specific Method of Generating Parametric Maps of Patlak K(i) without Blood Sampling or Metabolite Correction: A Feasibility Study
    George A Sayre
    UCSF Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143 0628, USA
    Int J Mol Imaging 2011:185083. 2011
    ....
  32. pmc Quantitative analysis of hypertrophic myocardium using diffusion tensor magnetic resonance imaging
    Nicholas Tran
    University of California, Department of Radiology and Biomedical Imaging, Physics Research Laboratory, 185 Berry Street, STE 350, San Francisco, United States
    J Med Imaging (Bellingham) 3:046001. 2016
    ..8 deg compared with 34.8 deg and 51.8 deg, respectively, in the normal hearts. Results demonstrate significantly altered myocardial fiber and laminar sheet structure in rats with hypertensive LVH...
  33. ncbi request reprint 18F Fluorocholine Dynamic Time-of-Flight PET/MR Imaging in Patients with Newly Diagnosed Intermediate- to High-Risk Prostate Cancer: Initial Clinical-Pathologic Comparisons
    Joon Young Choi
    From the Departments of Radiology and Biomedical Imaging J Y C, J Y, S M N, S B, J K, Y S, Radiation Oncology A J C, Y S, Anatomic Pathology J P S, and Urology H G N, P R C, University of California, San Francisco, San Francisco, Calif and Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon ro, Gangnam Gu, Seoul 06351, Republic of Korea J Y C
    Radiology . 2016
    ..sup>© RSNA, 2016 Online supplemental material is available for this article...
  34. doi request reprint Hybrid ZTE/Dixon MR-based Attenuation Correction for Quantitative Uptake Estimation of Pelvic Lesions in PET/MRI
    Andrew P Leynes
    Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA
    Med Phys . 2017
    ..This study introduces a new hybrid ZTE/Dixon MR-based attenuation correction (MRAC) method including bone density estimation for PET/MRI and quantifies the effects of bone attenuation on metastatic lesions uptake in the pelvis...
  35. pmc Temperature dependent operation of PSAPD-based compact gamma camera for SPECT imaging
    Sangtaek Kim
    Physics Research Laboratory, University of California, San Francisco, San Francisco, CA 94107 USA
    IEEE Trans Nucl Sci 58:2169-2174. 2011
    ..All PSAPD evaluations were conducted with an applied bias voltage that allowed the highest gain at a given temperature...
  36. pmc Differential Requirements for eIF4E Dose in Normal Development and Cancer
    Morgan L Truitt
    Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA
    Cell 162:59-71. 2015
    ..Our findings indicate eIF4E is maintained at levels in excess for normal development that are hijacked by cancer cells to drive a translational program supporting tumorigenesis...
  37. pmc Image reconstruction in higher dimensions: myocardial perfusion imaging of tracer dynamics with cardiac motion due to deformation and respiration
    Uttam M Shrestha
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA Structural Biology and Imaging Department, Lawrence Berkeley National Laboratory, Berkeley, CA, USA
    Phys Med Biol 60:8275-301. 2015
    ..Additionally, there is a trade-off between the number of gates and the number of projections per gate to achieve high contrast images. ..
  38. pmc Patient-specific dosimetry using pretherapy [¹²⁴I]m-iodobenzylguanidine ([¹²⁴I]mIBG) dynamic PET/CT imaging before [¹³¹I]mIBG targeted radionuclide therapy for neuroblastoma
    Shih Ying Huang
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, 94143 0946, USA
    Mol Imaging Biol 17:284-94. 2015
    ....
  39. doi request reprint Preclinical SPECT and SPECT/CT
    Youngho Seo
    Radiological Associate of Sacramento, University of California, San Francisco, CA, USA
    Recent Results Cancer Res 187:193-220. 2013
    ..Several of these advances as well as several specific applications in oncology are highlighted and areas needing further improvement are identified...
  40. pmc Functional imaging for prostate cancer: therapeutic implications
    Carina Mari Aparici
    Department of Radiology and Biomedical Imaging, University of California, and Nuclear Medicine Service, San Francisco Veterans Affairs Medical Center, San Francisco, CA 94107, USA
    Semin Nucl Med 42:328-42. 2012
    ..In this review article, we present the rationale of using functional radionuclide imaging and the therapeutic implications for each of radionuclide imaging agent that have been studied in human subjects...
  41. pmc Selective activation of p53-mediated tumour suppression in high-grade tumours
    Melissa R Junttila
    University of California San Francisco, Department of Pathology and Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94143 0502, USA
    Nature 468:567-71. 2010
    ..Importantly, the failure of low-level oncogenic Kras to engage p53 reveals inherent limits in the capacity of p53 to restrain early tumour evolution and in the efficacy of therapeutic p53 restoration to eradicate cancers...